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Grants and contracts awarded to Yale School of Medicine

Medicine@Yale, 2010 - November

Contents

November 2009 — February 2010

Federal

  • Karen Anderson, NIH, Exploring Novel Targeting Strategies for AIDS Protozoal Pathogens, 4 years, $1,655,000
  • Susan Baserga, NIH, The Architecture and Function of RNPs Required for Ribosome Biogenesis, 4 years, $1,779,285
  • Christopher Breuer, NIH, Investigating the Mechanisms of Vascular Neotissue Formation in Engineered Tissue, 5 years, $2,068,750
  • Arthur Broadus, NIH, Ihh and PTHrP Regulate Articular Chondrocyte Maintenance, 2 years, $409,613
  • Paul Cleary, NIH, National AIDS Prevention Research Centers Proposed Multi-Level Intervention Planning Workshop, 1 year, $88,835
  • Marie Egan, NIH, CFTR and the Immune Response, 5 years, $2,068,750
  • Barbara Ehrlich, Department of the Army, Strategies to Prevent Chemotherapy-Induced Peripheral Neuropathy, 2 years, $620,625
  • Jack Elias, NIH, BRP-39/YKL-40 in TH2 Inflammation and Asthma, 4 years, $1,655,000
  • Erol Fikrig, NIH, Interactions between Anaplasma phagocytophilum andIxodes scapularis, 5 years, $2,068,750
  • John Hwa, NIH, Pharmacogenetics of the Human Prostacyclin Receptor, 4 years, $1,656,491
  • Dewan Hyder, NIH, Energetics of Neuronal Populations by fMRI, 5 years, $2,068,750
  • Celina Juliano, NIH, Determining piwi Function using in vivo Imaging of Stem Cells in Hydra, 3 years, $143,670
  • Susan Kaech, NIH, iCyt Reflection Cell-Sorter: High-End Instrumentation Grant Program, 1 year, $898,724
  • Cathryn Kubera, NIH, Role of GLUK6 in Cerebellar Circuitry Development,3 years, $137,330
  • Brett Lindenbach, NIH, Molecular Determinants of Hepatitis C Virus Assembly, 5 years, $2,068,750
  • Laura Niklason, NIH, Lung Tissue Engineering, 4 years, $2,577,329
  • Pasko Rakic, NIH, Neurogenetic Processes in the Fetal Brain, 5 years, $5,406,186
  • Nancy Ruddle, NIH, Lymphatic Vessel Imaging, 2 years, $455,125
  • Kristin Rudenga, NIH, Influence of Physiological Significance, Preference, and Stress on Taste Coding, 2 years, $51,210
  • Gary Rudnick, NIH, Neurotransmitter Transporters, 5 years, $1,655,000
  • Joseph Santos-Sacchi, NIH, Structural Correlates of Prestin Activity, 5 years, $1,758,440
  • Mark Shlomchik, NIH, Mechanisms of Autoimmune Activation and Regulation by Innate Immune Receptors, 5 years, $768,890; NIH, Image Stream Analyzer, 1 year, $455,000
  • Karen Smith, NIH, The Role of Astrocytes in Cortical Interneuron Development, 4 years, $676,869
  • Dieter Söll, NSF, Expanding the Genetic Code with Phosphoserine and Phosphotyrosine, 3 years, $555,397
  • Jane Taylor, NIH, Cognitive Dysfunction after Chronic Cocaine Use, 5 years, $1,415,000
  • Susumu Tomita, NIH, Mechanism for Regulating Kainate-Type Glutamate Receptor Activity, 5 years, $2,068,750
  • Anthony Van den Pol, NIH, Response Properties of Hypothalamic MCH Neurons, 5 years, $1,810,155

Non-Federal

  • Vikki Abrahams, Burroughs Wellcome Fund, The Role of Placental Nod-Like Receptors in Infection-Associated Preterm Labor, 1 year, $50,000
  • Kyung-Heup Ahn, NARSAD, GABA–Dopamine Interactions and Psychosis, 2 years, $59,310
  • Emily Ansell, American Foundation for Suicide Prevention, Personality Disorders and Suicidal Behaviors: A Prospective Study of Associations, Mediators, and Moderators, 2 years, $85,000
  • Xiaoxiao Bai, Epilepsy Foundation of America, Neuroimaging Biomarkers of Network Dysfunction in Childhood Absence Epilepsy, 1 year, $45,000
  • Mounira Banasr, NARSAD, Implications of Glial Changes in the Development of Depressive-Like Behaviors, 2 years, $60,000
  • Diana Beardsley, ITP Foundation, Fcy Balance in Immune Thrombocytopenia, 1 year, $19,110
  • Vineet Bhandari, Washington University in St. Louis, Screening for Genetic Causes of Neonatal Respiratory Distress, 1 year, $10,450
  • Thomas Biederer, NARSAD, Neuronal Functions and Biochemical Pathways of SynCAM-Mediated Synapse Organization, 2 years, $60,000
  • Michael Bloch, NARSAD, Pilot Study of a Potent NMDA Receptor Antagonist in the Treatment of Obsessive-Compulsive Disorder, 2 years, $59,890
  • Angelique Bordey, McKnight Endowment Fund for Neuroscience,Cognitive Deficits in Tuberous Sclerosis Complex, 3 years, $300,000
  • Elizabeth Bradley, Avram Corporation, Master in Healthcare and Hospital Administration (MHA) Program, Ethiopia, 1 year, $324,195
  • Sonia Caprio, American Diabetes Association, Inc., Insulin Resistance in Obese Youth with Prediabetes, 4 years, $144,000
  • Richard Carson, Wyeth Pharmaceuticals Inc., Receptor Occupancy Assessed with PET in Nonhuman Primates II, 7 months, $348,339
  • Heidi Chen, American Urogynecologic Society, Using Quantitative Sensory Testing of the Sensory Distribution of the Pudendal Nerve in Predicting Success of Sacral Neuromodulation, 1 year, $10,000
  • Jersey Chen, American Heart Association, Geographic Variation in Imaging with Cardiac Stress Testing, 2 years, $104,720
  • Lara Chepenik, NARSAD, Interhemispheric Connectivity and Rapid Cycling in Bipolar Disorder, 2 years, $60,000
  • Jaehyuk Choi, American Skin Association, A Forward Genetic Screen for Tumor Suppressor Genes using Transposon Mutagenesis in Mouse Skin, 1 year, $15,000
  • Young Choi, Dong-A Pharmaceutical Company, Emerging Role of Estrogen Receptor and Isoforms in Breast Cancer, 3 years, $105,000
  • Joseph Craft, American Autoimmune Related Diseases Association, Inc., Follicular Helper T Cells in SLE, 1 year, $10,000
  • Pietro De Camilli, Lowe Syndrome Trust, Novel Interactors of the Lowe Syndrome Protein OCRL, 2 years, $120,000
  • Sachin Desai, Gerber Foundation, The Effectiveness of Rotavirus Vaccine in Preventing Hospitalization of Young Children, 1 year, $20,000
  • Ronald Duman, Hope for Depression Research Foundation, Influence of Isolation Stress on Cell Proliferation and Neurotrophic Factor Signaling: Reversal by Opiate Drug Treatments, 2 years, $110,000
  • Andrew Epstein, University of Pennsylvania, Comparative Effectiveness of Cardiovascular Devices and Medicare Cost Growth, 3 years, $34,268
  • David Feliciano, Epilepsy Foundation of America, Electrophysiological Analysis of a Malformation of Cortical Development, 1 year, $45,000
  • John Geibel, Institute for OneWorld Health, Proposed Research to be Conducted in Preliminary Phase of the Joint Yale/IOWH Program on Employment of Calcimimetics as a Treatment for ADI, 1 year, $120,000
  • Joel Gelernter, Butler Hospital, Childhood Maltreatment: Risk and Resilience, 4 years, $55,871
  • John Giuliano Jr., Children’s Hospital Corporation, Novel Influenza A (H1N1) Surveillance Registry, 9 months, $21,600
  • Rosana Gonzalez-Colaso, Physician Assistant Education Association,Putting Physician Assistants on the Map: Geographic Analysis of Workforce Capacity, 1 year, $7,000
  • Bonnie Gould Rothberg, LAM Treatment Alliance, Mechanisms of Benign Metastasis in Kidney AMLS, 1 year, $60,000
  • David Hafler, National Multiple Sclerosis Society, Collaborative Multiple Sclerosis Research Center Award, 5 years, $742,500; University of California, San Francisco, A Haplotype Map for Multiple Sclerosis, 18 months, $142,624
  • Jonas Hannestad, NARSAD, The Effect of Citalopram on Inflammation-Induced Depressive Symptoms, 2 years, $45,850
  • Robert Heimer, State of CT Department of Public Health, Emerging Infections, 2 years, $3,922,258
  • Erica Herzog, Scleroderma Foundation, Semaphorin 7A Mediated Effects on Fibrocyte Biology, 2 years, $150,000
  • Mark Horowitz, Maine Medical Center Research Institute,Interdisciplinary Study of Marrow Adiposity, Mineral Metabolism, and Energy Balance, 1 year, $124,125
  • Steven Kerfoot, Multiple Sclerosis Society of Canada, Identification of Cellular Interactions through which B Cells Drive Central Nervous System Autoimmune Disease in vivo, 6 years, $260,000
  • Tae Hoon Kim, Harvard University, Integrative Systems Biology Approaches to Auditory Hair Cell Regeneration, 5 years, $413,750
  • Anthony Koleske, Breast Cancer Alliance, Inc., Inhibition of Breast Cancer Invasiveness via Targeting of an Arg Contactin Switch, 1 year, $100,000
  • Diane Krause, Community Foundation for Southeast Michigan, SRF and Myelodysplasia, 2 years, $50,000
  • Gary Kupfer, St. Baldrick’s Foundation, The Yale Pediatric Oncology Psychological Service, 1 year, $50,000
  • Tukiet Lam, University of Chicago, Proteomic Assays of Neuronal Protein Palmitoylation, 1 year, $24,337
  • Forrester Lee, Robert Wood Johnson Foundation, Summer Medical and Dental Education Program, 2 years, $567,686
  • Soo Hee Lee, Jane Coffin Childs Memorial Fund, Function and Mechanism of Action of a Novel Argonaute-Like Protein in the Mitochondrion of Trypanosoma brucei, 21 months, $82,000
  • Chiang-Shan Li, NARSAD, Neural Predictors of Anti-Depressant Efficacy in Obsessive-Compulsive Disorder, 2 years, $60,000
  • John MacMicking, Burroughs Wellcome Fund, Support to Present Seminar Speaker, Harmit Malik, 6 months, $1,000
  • Mark Mamula, Genentech Foundation for Biomedical Sciences,Molecular Probes for the Detection of Isoaspartyl in Proteins, 1 year, $80,000
  • David Matuskey, NARSAD, Genetic Vulnerability to Paranoia: An [11C]PHNO D2High PET Study in Human Cocaine Use, 2 years, $60,000
  • James McPartland, NARSAD, Neural Correlates of Social Perception in Autism, 2 years, $60,000
  • Pramod Mistry, Shire Human Genetics Therapies, Inc., Mechanisms of the Effect of Velaglucetase vs. Imiglucetase Enzyme Replacement Therapy in Authentic Mouse Model of Type 1 Gaucher Disease, 2 years, $393,506
  • Deepak Narayan, American Society of Maxillofacial Surgeons,Hemangiomas are Stem Cell Tumors of Pericyte Origin, 1 year, $6,390
  • Joseph Piepmeier, Voices Against Brain Cancer, Targeted Delivery of Nanoparticle-Based Combination Therapy for Glioblastoma, 1 year, $50,587
  • Christopher Pittenger, NARSAD, Deconstructing Habits: The Differential Contributions of Striatal Subregions to Procedural Learning, 2 years, $60,000
  • Valerie Reinke, Stanford University, Global Identification of Transcription Factor Binding Sites in C. elegans, 9 months, $1,590,767
  • Lawrence Rizzolo, International Retinal Research Foundation, Co-Maturation RPE and Retinal Neurons Derived from Stem Cells, 1 year, $100,000
  • Frederick Romberg, American Heart Association, High-Resolution Time-Frequency Analysis of Neurovascular Responses to Ischemic Challenges, 6 months, $11,000
  • Carla Rothlin, Crohn’s & Colitis Foundation of America, Role of TAM Receptor Signaling in Intestinal Mucosal Homeostasis, 3 years, $386,100
  • Gerard Sanacora, Merck Sharp & Dohme, In vivo Evaluation of Drug Effects on Glutamate Neurotransmission using Magnetic Resonance Spectroscopy, 2 years, $483,403
  • Mark Shlomchik, University of Florida, B Cell Developmental Defects in Murine Memory, 1 year, $280,793; University of Massachusetts,Activation and Regulation of Autoimmunity by Innate Immune Sensing Pathways, 5 years, $2,247,390
  • Patrick Skosnik, NARSAD, Cannabis Use and Schizophrenia-Related Biomarkers: A Longitudinal Study, 2 years, $60,000
  • Karen Smith, NARSAD, Postnatal Inhibitory Neuron Maturation, 2 years, $60,000
  • Michael Stankewich, National Ataxia Foundation, Molecular Mechanisms of Beta 3 Spectrin in Spinocerebellar Ataxis 5 (SCA5), 1 year, $35,000
  • Philip Stein, Genzyme Corporation, Comprehensive Fellowship Training in Lysosomal Diseases, 18 months, $106,438
  • Hanna Stevens, NARSAD, Prenatal Stress and the Development of Inhibitory Interneurons, 2 years, $60,000
  • Stephen Strittmatter, Christopher and Dana Reeve Foundation, PET Imaging of Axonal Regeneration after Spinal Cord Injury, 1 year, $62,334
  • Dorothy Stubbe, Campagna Associates, LLP, Forensic Evaluations, 7 months, $17,250
  • Suman Tandon, American Heart Association, Effect of Cardiac Resynchronization Therapy on Myocardial Mechanics and Flow: Evaluation with 3D 82Rb PET/CT, 2 years, $110,000
  • Cenk Tek, NARSAD, A Pilot Trial of Acute N-Acetylcysteine Effects on Working Memory in Schizophrenia, 2 years, $60,000
  • Whitney Tolpinrud, American Skin Association, Mechanistic Elucidation of Photopheresis, A Treatment of Cutaneous T Cell Lymphoma, 1 year, $7,000
  • Tamara Vanderwal, American Academy of Child and Adolescent Psychiatry, Neurophysiological Correlates of Treatment with Guanfacine in Children with ADD, 6 months, $9,000
  • Hongwei Wang, Richard & Susan Smith Family Foundation, Structure and Mechanism of the Human RISC-Loading Complex, 3 years, $300,000
  • Sherman Weissman, University of Massachusetts, Gene Expression in Mature Neutrophils, 1 year, $49,999
  • Yong Xiong, March of Dimes, Molecular Dissection of Fanconi Anemia, 2 years, $150,000
  • Qin Yan, Breast Cancer Alliance, Inc., Roles of Histone Demethylase JARIDIB in Breast Cancer, 2 years, $125,000
  • Xiaoyong Yang, American Diabetes Association, Inc., Regulation of Metabolic Homeostasis by Cyclic O-GlcNAc Modification, 3 years, $400,200
  • Yawei Zhang, American Cancer Society, Inc., Epidemiology Study of Thyroid Cancer, 5 years, $1,020,000
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