Andrew Koo, MD
Hospital ResidentCards
About
Research
Publications
2025
SLAMF1 as a Risk Biomarker for Nontraumatic SAH: Evidence From a Multiomics Study.
Renedo D, Koo A, Sujijantarat N, Clocchiatti-Tuozzo S, Huo S, Acosta J, Hebert R, Gunel M, Sansing L, Sheth K, Falcone G, Matouk C, Rivier C. SLAMF1 as a Risk Biomarker for Nontraumatic SAH: Evidence From a Multiomics Study. Stroke 2025 PMID: 41221640, DOI: 10.1161/strokeaha.125.052604.Peer-Reviewed Original ResearchMendelian randomizationSubarachnoid hemorrhage riskIncident SAH casesNontraumatic subarachnoid hemorrhageSubarachnoid hemorrhageUK BiobankSmoking statusClinical priorityPrevention strategiesCellular expression profilesCox proportional hazards analysisProportional hazards analysisRisk predictionCis-protein quantitative trait lociCD4 naive cellsSAH casesRisk biomarkersSubarachnoid hemorrhage pathophysiologyAdaptive immune responsesHuman hematopoietic progenitorsFollow-upQuantitative trait lociSingle-cell transcriptome analysisRiskCerebrovascular eventsImpact of frailty on morbidity and mortality in traumatic blunt cerebrovascular injury
Smith W, Serrato P, Ghanekar S, Owolo E, Fathima B, Padmanaban V, Koo A, Shankar G, Stapleton C, Rabinov J, Matouk C, Elsamadicy A, Patel A, Sujijantarat N. Impact of frailty on morbidity and mortality in traumatic blunt cerebrovascular injury. Clinical Neurology And Neurosurgery 2025, 259: 109208. PMID: 41161149, DOI: 10.1016/j.clineuro.2025.109208.Peer-Reviewed Original ResearchConceptsBlunt cerebrovascular injuryTrauma Quality ProgramsIn-Hospital MortalityNon-routine dischargeBlunt cerebrovascular injury patientsNon-frailPredictors of adverse eventsAmerican CollegeBCVI patientsMotor vehicle traumaAdverse eventsPredominant mechanism of injuryCritical care populationEffect of frailtyCerebrovascular injuryMechanism of injuryMultivariate logistic regressionImpact of frailtyCare populationIndependent predictorsClinical outcomesPre-frailLow severity injuriesFive-item modified frailty indexPre-frail patientsImmune Characterization of Intracranial Aneurysms Using Noninvasive Endoluminal Biopsy With High-Dimensional Single-Cell Phenotyping
Antonios J, Gultekin B, Theriault B, Yalcin K, Miyagishima D, Adenu-Mensah N, Sujijantarat N, Koo A, Haynes J, Cedeno P, Johnson M, Hebert R, Matouk C, Barak T, Gunel M. Immune Characterization of Intracranial Aneurysms Using Noninvasive Endoluminal Biopsy With High-Dimensional Single-Cell Phenotyping. Neurology 2025, 105: e214185. PMID: 40997288, DOI: 10.1212/wnl.0000000000214185.Peer-Reviewed Original ResearchConceptsIntracranial aneurysmsEndoluminal biopsyImmune landscapeImmune characterizationSubarachnoid hemorrhageGroup 1Characterization of intracranial aneurysmsDilation of cerebral arteriesPathological dilatationProspective observational cohort studyUpregulation of CD38Neutrophil-dominated inflammationImmune regulatory mechanismsAssociated with aneurysm growthYale-New Haven HospitalPathological dilatations of cerebral arteriesFisher's exact testObservational cohort studyImmune-based biomarkersUnruptured intracranial aneurysmsNo significant associationImmune signaturesImmunomodulatory therapyHLA-DRNeutrophil predominanceProcedure duration predicts outcomes more than prehospital delay in endovascular stroke treatment
Saad H, Koo A, Grossberg J, Tianwen M, Howard B, Sowlat M, Baba B, Chacon A, Jabbour P, Rai A, Dye J, Alaraj A, Cawley C, Tong F, Akbik F, Pabaney A, Ezzeldin M, Fiorella D, Yoshimura S, Kim J, Goyal N, Arthur A, Fragata I, Siddiqui F, Mascitelli J, Matouk C, Maier I, Park M, Levitt M, Grandhi R, Psychogios M, Wolfe S, Starke R, Shaban A, Samaniego E, Tanweer O, Romano D, Navia P, Cuellar H, Polifka A, Osbun J, Moss M, Limaye K, Mokin M, Brinjikji W, Daglioglu E, Williamson R, Altschul D, Ogilvy C, Crosa R, Gory B, Paul A, Kan P, Casagrande W, Chowdhry S, Stiefel M, Spiotta A, Alawieh A. Procedure duration predicts outcomes more than prehospital delay in endovascular stroke treatment. Journal Of NeuroInterventional Surgery 2025, jnis-2025-023906. PMID: 40973492, DOI: 10.1136/jnis-2025-023906.Peer-Reviewed Original ResearchAcute ischemic strokeModified Rankin ScaleStroke systemsEndovascular thrombectomyStroke systems of carePropensity score matchingSystems of careFunctional outcomesMarginal effects modelsSymptomatic intracranial hemorrhage rateRate of functional independencePrehospital delayIntracranial hemorrhage rateAssociated with functional outcomeInter-center differencesInternational stroke centersFunctional independenceHigher RatesEndovascular stroke treatmentHemorrhage ratePatient outcomesProcedure durationRetrospective analysisStroke centersRankin ScaleCarotid Revascularization in the Modern Era: A Comparative Review of Carotid Endarterectomy, Carotid Angioplasty and Stenting, and Transcarotid Artery Revascularization
Amllay A, Koo A, Renedo D, Padmanaban V, Teasdale B, Hebert R, Arat A, Duda T, Schindler J, Stapleton C, Rabinov J, Patel A, Matouk C, Sujijantarat N. Carotid Revascularization in the Modern Era: A Comparative Review of Carotid Endarterectomy, Carotid Angioplasty and Stenting, and Transcarotid Artery Revascularization. Seminars In Neurology 2025 PMID: 40889763, DOI: 10.1055/a-2685-3141.Peer-Reviewed Original ResearchTranscarotid artery revascularizationCarotid endarterectomyArtery revascularizationCarotid angioplastyRevascularization strategyIndividual risk-benefit assessmentTF-CASOptimal medical therapyGold standard procedureCarotid artery stenosisCompared to carotid endarterectomyAcute ischemic strokeRisk-benefit assessmentAsymptomatic patientsSymptomatic patientsSurgical riskCarotid revascularization strategiesMedical therapySurgical interventionSurgical techniqueCarotid revascularizationClinical indicationsArtery stenosisRevascularizationPatientsCharacterizing Stroke Clots Using Single‐Cell Sequencing
Renedo D, Barak T, DeLong J, Acosta J, Sujijantarat N, Koo A, Rivier C, Clocchiatti-Tuozzo S, Huo S, Antonios J, Giles J, Falcone G, Sheth K, Hebert R, Gunel M, Sansing L, Navaratnam D, Matouk C. Characterizing Stroke Clots Using Single‐Cell Sequencing. Journal Of The American Heart Association 2025, 14: ejaha/2025/041738-t. PMID: 40878981, PMCID: PMC12553457, DOI: 10.1161/jaha.125.041738.Peer-Reviewed Original ResearchConceptsMulti-marker analysisGene expressionMulti-marker Analysis of GenoMic AnnotationCell type-specific gene expressionT cellsGenome-wide association studiesGene expression of cellsSingle-cell RNA sequencingPotential biomarkersTIMP1Genes associated with atherosclerosisHLA-DRB1*01Single-cell sequencingExpression of genesUpregulated expression of genesGene expression profilesCarotid atherosclerosisGenome annotationCD8 T cellsUpregulated expressionImmune cell compositionAssociation studiesNatural killer cellsImmune cell populationsLarge vessel occlusion strokeGlobal gender representation in neurointerventional surgery: a natural language processing analysis of journal publications
Renedo D, Koo A, Amllay A, Sujijantarat N, Fathima B, Haynes J, Falcone G, Sheth K, Fadel S, Johnson M, Hebert R, Rivier C, Matouk C. Global gender representation in neurointerventional surgery: a natural language processing analysis of journal publications. Journal Of NeuroInterventional Surgery 2025, jnis-2025-023956. PMID: 40813072, DOI: 10.1136/jnis-2025-023956.Peer-Reviewed Original ResearchNatural language processingNatural language processing methodsExtract metadataNatural language processing analysisLanguage processingArtificial intelligenceFemale last authorshipAcademic publishingAuthorship ratesFemale first authorshipAuthor affiliationJournal publicationsInstitutional affiliationFirst authorshipRepresentationSurgery journalsAPIAuthorshipProcess analysisMetadataFemale authorshipJournalsIntelligenceE-057 Impact of preoperative nutritional status on morbidity and mortality in elderly adults undergoing carotid endarterectomy
Koo A, Menon S, Reeves B, Stogniy S, Hebert R, Matouk C. E-057 Impact of preoperative nutritional status on morbidity and mortality in elderly adults undergoing carotid endarterectomy. 2025, a130.1-a130. DOI: 10.1136/jnis-2025-snis.173.Peer-Reviewed Original ResearchE-167 Single session middle meningeal artery embolization and surgical evacuation for chronic subdural hematoma
Koo A, Stogniy S, Elsamadicy A, Menon S, Renedo D, Reeves B, Sujijantarat N, Hebert R, de Havenon A, Sheth K, Matouk C. E-167 Single session middle meningeal artery embolization and surgical evacuation for chronic subdural hematoma. 2025, a204-a205. DOI: 10.1136/jnis-2025-snis.282.Peer-Reviewed Original ResearchE-090 Acute ischemic stroke risk following cardiac interventions in the United States from 2016 to 2021
Koo A, Zhou L, Hameed I, Rivier C, Clocchiatti-Tuozzo S, Kamel H, Falcone G, Ney J, Sharma R, Matouk C, Yaghi S, Sheth K, de Havenon A. E-090 Acute ischemic stroke risk following cardiac interventions in the United States from 2016 to 2021. 2025, a153-a155. DOI: 10.1136/jnis-2025-snis.206.Peer-Reviewed Original Research
News
News
- September 29, 2025Source: Neurology
Immune Characterization of Intracranial Aneurysms Using Noninvasive Endoluminal Biopsy With High-Dimensional Single-Cell Phenotyping
- August 15, 2025Source: Journal of NeuroInterventional Surgery
Global gender representation in neurointerventional surgery: a natural language processing analysis of journal publications
Get In Touch
Contacts
Email