Xiao Xu, PhD, MA
Associate Professor Adjunct of Obstetrics, Gynecology & Reproductive SciencesCards
Contact Info
Obstetrics, Gynecology & Reproductive Sciences
310 Cedar Street, LSOG 205B, PO Box 208063
New Haven, CT 06510
United States
About
Titles
Associate Professor Adjunct of Obstetrics, Gynecology & Reproductive Sciences
Biography
Dr. Xiao Xu is an Associate Professor in the Department of Obstetrics, Gynecology and Reproductive Sciences at Yale School of Medicine, and a faculty member of Yale Cancer Center and Yale Cancer Outcomes, Public Policy and Effectiveness Research Center (COPPER). As a health economist and health services researcher, her work seeks to promote the delivery of high-quality and high-value care. Her research focuses on examining and identifying factors that influence the quality, outcomes, and value of care, with a focus on women's health care. Her recent studies examined hospital and geographic variation in care utilization, costs, and patient outcomes; comparative effectiveness and cost effectiveness of alternative treatment strategies; and gender and racial/ethnic disparities in health and health care. Dr. Xu is also actively involved in the teaching of medical students, clinical residents/fellows, and postgraduate/postdoctoral fellows. She mentors trainees on research design and methodology, and lectures on methods of data collection, data analysis, and cost effectiveness evaluation.
Dr. Xu has served as a principal investigator or co-investigator on multiple research grants funded by the National Institutes of Health (NIH), Agency for Healthcare Research and Quality (AHRQ), and various research foundations. She received honorable mention for the Aetna Susan B. Anthony Award for excellence in research on older women and public health from the American Public Health Association (Gerontological Health Section) in 2005, the Frank J. McDevitt Excellence in Research Award in Policy Research from the Blue Cross Blue Shield of Michigan Foundation in 2008 and 2011, and the Carol Weisman & Gary Chase Gender-Based Research Award from the AcademyHealth in 2017. Dr. Xu is a member of the American College of Obstetricians and Gynecologists, AcademyHealth, the International Health Economics Association, and the Gerontological Society of America.
Appointments
Departments & Organizations
- COPPER Center
- Gaither Lab
- Maternal-Fetal Medicine
- Yale Cancer Center
- Yale Ventures
Education & Training
- PhD
- Wayne State University, Economics (2004)
- MA
- Wayne State University, Economics (2002)
Research
Overview
Medical Subject Headings (MeSH)
Research at a Glance
Yale Co-Authors
Publications Timeline
Research Interests
Jessica Illuzzi, MD, MS, FACOG
Vrunda Desai, MD, FACOG
Harlan Krumholz, MD, SM
Jeph Herrin, PhD
Cary Gross, MD
Ilana Richman, MD, MHS
Costs and Cost Analysis
Publications
2024
Bundled Payments for Care Improvement and Quality of Care and Outcomes in Heart Failure
Oddleifson D, Holmes D, Alhanti B, Xu X, Heidenreich P, Wadhera R, Allen L, Greene S, Fonarow G, Spatz E, Desai N. Bundled Payments for Care Improvement and Quality of Care and Outcomes in Heart Failure. JAMA Cardiology 2024, 9: 222-232. PMID: 38170516, PMCID: PMC10765313, DOI: 10.1001/jamacardio.2023.5009.Peer-Reviewed Original ResearchCitationsAltmetricConceptsNon-BPCI hospitalsCause readmission rateReadmission ratesHeart failureSignificant differential changesCare measuresHospital participationBPCI hospitalsHospital mortalityEnzyme inhibitors/angiotensin receptor blockersMortality rateBPCI programAngiotensin receptor neprilysin inhibitorEvidence-based β-blockersGuidelines-Heart Failure registryEnd pointBPCI Model 2Heart failure educationAngiotensin receptor blockersPrimary end pointSecondary end pointsThird of patientsCardiac resynchronization therapyCause mortality ratesHeart failure program
2023
Black-White differences in uterine cancer symptomatology and stage at diagnosis
Xu X, Chen L, Nunez-Smith M, Clark M, Ferris J, Hershman D, Wright J. Black-White differences in uterine cancer symptomatology and stage at diagnosis. Gynecologic Oncology 2023, 180: 118-125. PMID: 38091770, PMCID: PMC10922746, DOI: 10.1016/j.ygyno.2023.11.029.Peer-Reviewed Original ResearchCitationsAltmetricConceptsAdvanced stage diagnosisWhite patientsPostmenopausal bleedingPatient characteristicsEnd Results-Medicare databaseBlack-white differencesBlack-White disparitiesBlack patientsUterine cancerCancer symptomsHigh riskPatientsAdvanced stageSymptomsDiagnosisCancer symptomatologyRegression modelsRiskLarge proportionBleedingHistologyCancerEpidemiologySymptomatologyMonthsTimeliness of diagnostic evaluation for postmenopausal bleeding: A retrospective cohort study using claims data
Xu X, Chen L, Nunez-Smith M, Clark M, Wright J. Timeliness of diagnostic evaluation for postmenopausal bleeding: A retrospective cohort study using claims data. PLOS ONE 2023, 18: e0289692. PMID: 37682914, PMCID: PMC10490884, DOI: 10.1371/journal.pone.0289692.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsPostmenopausal bleedingFirst diagnostic procedureDiagnostic evaluationDiagnostic proceduresGynecologic conditionsMedicaid patientsCox proportional hazards modelPrompt diagnostic evaluationRetrospective cohort studyMarketScan Research DatabasesAdditional risk factorsNon-clinical factorsCommon gynecologic conditionProportional hazards modelLower ratesCohort studyMost patientsPatient characteristicsBenign etiologyGynecologic cancerCancer patientsPreventive careUterine cancerInsurance typeRisk factorsRacial disparities in diagnostic evaluation of uterine cancer among Medicaid beneficiaries
Xu X, Chen L, Nunez-Smith M, Clark M, Wright J. Racial disparities in diagnostic evaluation of uterine cancer among Medicaid beneficiaries. Journal Of The National Cancer Institute 2023, 115: 636-643. PMID: 36788453, PMCID: PMC10248843, DOI: 10.1093/jnci/djad027.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsAbnormal uterine bleedingWhite patientsUterine cancerFirst diagnostic procedureDiagnostic evaluationBlack patientsDiagnostic proceduresBlack-White disparitiesManagement visitsMarketScan Multi-State Medicaid DatabaseMulti-State Medicaid DatabaseUterine bleedingPatient characteristicsMedicaid databaseEarly diagnosisMedicaid beneficiariesMultivariable regressionPatientsCancerRacial disparitiesDiagnosisVisitsMore evaluationDisparitiesBleeding
2022
Containment Bag Use Among Women Who Undergo Hysterectomy With Laparoscopic Power Morcellation.
Wright JD, Chen L, Melamed A, Clair CMS, Hou JY, Khoury-Collado F, Gockley A, Accordino M, Hershman DL, Xu X. Containment Bag Use Among Women Who Undergo Hysterectomy With Laparoscopic Power Morcellation. Obstetrics And Gynecology 2022 PMID: 35926199, DOI: 10.1097/AOG.0000000000004886.Peer-Reviewed Original ResearchMode of Delivery in Antepartum Singleton Stillbirths and Associated Risk Factors
Underwood K, Reddy UM, Hosier H, Sweeney L, Campbell KH, Xu X. Mode of Delivery in Antepartum Singleton Stillbirths and Associated Risk Factors. American Journal Of Perinatology 2022, 41: e193-e203. PMID: 35850142, DOI: 10.1055/s-0042-1750795.Peer-Reviewed Original ResearchCitationsConceptsMode of deliveryAntepartum stillbirthCesarean deliveryPrior cesareanVaginal deliveryMaternal hospital discharge recordsLower likelihoodAssociated risk factorsWeeks of gestationHospital discharge recordsNon-clinical factorsUrban teaching hospitalMultivariable regression analysisPopulation-based sampleFetal death certificatesSingleton stillbirthsPrimary outcomeHospital characteristicsRisk factorsTeaching hospitalDeath certificatesMultivariable regressionCesareanPatientsStillbirthMaternal Outcomes in Subsequent Pregnancies After Classical Cesarean Delivery
Thompson BB, Reddy UM, Burn M, Abdel-Razeq S, Xu X. Maternal Outcomes in Subsequent Pregnancies After Classical Cesarean Delivery. Obstetrics And Gynecology 2022, 140: 212-219. PMID: 35852271, DOI: 10.1097/aog.0000000000004869.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsPrior classical cesarean deliveryLow transverse cesarean deliveryPrior low transverse cesarean deliveryClassical cesarean deliverySevere maternal morbidityClinical risk factorsCesarean deliveryUterine ruptureMaternal outcomesSubsequent pregnancyHospital characteristicsRate of SMMPatient clinical risk factorsNational Inpatient Sample databaseLive singleton birthsWeeks of gestationMode of deliveryCross-sectional analysisMaternal morbiditySingleton birthsRisk factorsOutcome measuresMultivariable regressionHigh riskPropensity score methodsPerioperative magnetic resonance imaging in breast cancer care: Distinct adoption trajectories among physician patient-sharing networks
Xu X, Soulos PR, Herrin J, Wang SY, Pollack CE, Killelea BK, Forman HP, Gross CP. Perioperative magnetic resonance imaging in breast cancer care: Distinct adoption trajectories among physician patient-sharing networks. PLOS ONE 2022, 17: e0265188. PMID: 35290417, PMCID: PMC8923453, DOI: 10.1371/journal.pone.0265188.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsPhysician patient-sharing networksPerioperative magnetic resonance imagingClinical risk factorsMagnetic resonance imagingPatient clinical risk factorsPatient-sharing networksBreast cancer careRisk-adjusted ratesMastectomy usePhysician networksCancer careRisk factorsEnd Results-Medicare databaseCharacteristics of patientsProportion of patientsBreast cancer surgeryComposition of patientsMRI adoptionDistinct trajectoriesMore patientsCancer surgeryClinical outcomesCancer specialistsMRI usePatientsSafety Warning about Laparoscopic Power Morcellation in Hysterectomy: A Cost-Effectiveness Analysis of National Impact
Xu X, Desai VB, Schwartz PE, Gross CP, Lin H, Schymura MJ, Wright JD. Safety Warning about Laparoscopic Power Morcellation in Hysterectomy: A Cost-Effectiveness Analysis of National Impact. Women's Health Reports 2022, 3: 369-384. PMID: 35415718, PMCID: PMC8994439, DOI: 10.1089/whr.2021.0101.Peer-Reviewed Original ResearchCitationsAltmetricSurgical Complications and Hospital Costs in Robot-Assisted Versus Conventional Laparoscopic Hysterectomy With Concurrent Sacrocolpopexy: Analysis of the Nationwide Readmissions Database
Andiman SE, Bui A, Ascher-Walsh C, Wright J, Xu X. Surgical Complications and Hospital Costs in Robot-Assisted Versus Conventional Laparoscopic Hysterectomy With Concurrent Sacrocolpopexy: Analysis of the Nationwide Readmissions Database. Urogynecology 2022, 28: e142-e148. PMID: 35113048, DOI: 10.1097/spv.0000000000001133.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsConventional laparoscopic procedureConventional laparoscopic hysterectomyNationwide Readmissions DatabasePerioperative complicationsLaparoscopic hysterectomyLaparoscopic proceduresHospital costsMajor perioperative complicationsConventional laparoscopic approachMultivariable regression analysisRobot-assisted approachLarge national databaseProcedure codesSurgical complicationsInvasive hysterectomyLaparoscopic approachHysterectomyLower riskComplicationsReadmissionSacrocolpopexyPatient linkageNational databaseWeighted samplePatients
News
News
- June 12, 2023
ASCO 2023 Wrap-Up
- May 18, 2023
Yale Cancer Center and Smilow Cancer Hospital Physicians and Scientists Presenting Latest Advances at 2023 ASCO Annual Meeting
- February 14, 2023Source: YaleNews
Black Patients Wait Longer for Uterine Cancer Testing, Diagnosis
- June 08, 2021
Digital Breast Tomosynthesis Offers Modest Benefits over Standard Mammography
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Contacts
Obstetrics, Gynecology & Reproductive Sciences
310 Cedar Street, LSOG 205B, PO Box 208063
New Haven, CT 06510
United States