2022
Poor outcomes in both infection and colonization with carbapenem-resistant Enterobacterales
Howard-Anderson JR, Earley M, Komarow L, Abbo L, Anderson DJ, Gallagher JC, Grant M, Kim A, Bonomo RA, van Duin D, Muñoz-Price LS, Jacob JT. Poor outcomes in both infection and colonization with carbapenem-resistant Enterobacterales. Infection Control And Hospital Epidemiology 2022, 43: 1840-1846. PMID: 35105408, PMCID: PMC9343470, DOI: 10.1017/ice.2022.4.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Bacterial AgentsCarbapenemsEnterobacteriaceaeEnterobacteriaceae InfectionsHumansRespiratory SoundsConceptsCRE colonizationClinical outcomesCRE infectionsTract colonizationEpidemiology of patientsOutcomes of patientsProspective observational cohortCharacteristics of patientsOverall clinical outcomeShort-term acute care hospitalsUrinary tract colonizationCarbapenem-resistant EnterobacteralesRespiratory tract colonizationAcute care hospitalsDesirable clinical outcomesObservational cohortReadmission ratesSecondary outcomesPrimary outcomePoor outcomeUrinary tractRespiratory tractPatientsBetter outcomesClinical cultures
2020
Efficacy and safety of chronic antimicrobial suppression therapy for left ventricular assist device driveline infections: A single‐center descriptive experience
Radcliffe C, Doilicho N, Niu YS, Grant M. Efficacy and safety of chronic antimicrobial suppression therapy for left ventricular assist device driveline infections: A single‐center descriptive experience. Transplant Infectious Disease 2020, 22: e13379. PMID: 32574417, DOI: 10.1111/tid.13379.Peer-Reviewed Original ResearchMeSH KeywordsAnti-Bacterial AgentsAnti-Infective AgentsFemaleHeart FailureHeart-Assist DevicesHumansMaleMiddle AgedProsthesis-Related InfectionsRetrospective StudiesConceptsCAS therapyDriveline infectionSuppression therapyTreatment failureVentricular assist device driveline infectionsShort-term antimicrobial therapyExperienced treatment failureTertiary transplant centerChronic kidney diseaseCornerstone of managementContinuous-flow LVADInfectious complicationsAdverse eventsLocal debridementRetrospective reviewTransplant centersKidney diseaseStable symptomsMean ageAntimicrobial therapyCommon causePatientsTherapySuccessful outcomeInfectionOver 870 days of successful antibiotic suppression therapy for VRE‐infected left ventricular assist device
Radcliffe C, Grant M. Over 870 days of successful antibiotic suppression therapy for VRE‐infected left ventricular assist device. Journal Of Cardiac Surgery 2020, 35: 1746-1748. PMID: 32557822, DOI: 10.1111/jocs.14690.Peer-Reviewed Case Reports and Technical NotesConceptsVancomycin-resistant Enterococcus faeciumSuppression therapyVentricular assist devicePocket infectionPump exchangeAssist deviceMethicillin-sensitive Staphylococcus aureusAntibiotic suppression therapyLeft ventricular assist deviceUse of daptomycinAdvanced heart failureSymptomatic adverse eventsHeartMate II LVADLong-term suppressionMultidrug-resistant pathogensSurgical drainageAdverse eventsCommon complicationHeart failureClinical challengeInfectionDevice placementTherapyEnterococcus faeciumStaphylococcus aureusNontuberculous mycobacterial infections in left ventricular assist device patients
Radcliffe C, Doilicho N, Grant M. Nontuberculous mycobacterial infections in left ventricular assist device patients. Journal Of Cardiac Surgery 2020, 35: 1138-1141. PMID: 32253770, DOI: 10.1111/jocs.14530.Peer-Reviewed Case Reports and Technical NotesConceptsNontuberculous mycobacterial infectionNTM infectionMycobacterial infectionLeft ventricular assist device patientsVentricular assist device patientsRefractory heart failureContinuous-flow LVADVentricular assist deviceLVAD infectionGram-negative enteric bacteriaLVAD patientsDevice patientsHeart failureDriveline infectionDevice exchangeMost infectionsClinical challengeNegative culturesAssist deviceSystematic reviewInfectionDevice placementMycobacterium fortuitumStaphylococcal sppPatients
2019
Actinomyces neuii: a case report of a rare cause of acute infective endocarditis and literature review
Yang WT, Grant M. Actinomyces neuii: a case report of a rare cause of acute infective endocarditis and literature review. BMC Infectious Diseases 2019, 19: 511. PMID: 31182045, PMCID: PMC6558687, DOI: 10.1186/s12879-019-4149-2.Peer-Reviewed Case Reports and Technical NotesMeSH KeywordsActinomycesActinomycosisAcute DiseaseAnti-Bacterial AgentsEchocardiographyEndocarditisHumansMaleMiddle AgedConceptsInfective endocarditisActinomyces sppEnd-stage renal diseaseBilateral cerebral infarctsOral antibiotic therapyAcute infective endocarditisStage renal diseaseVulnerable patient populationBackgroundInfective endocarditisSeptic emboliValvular surgeryAcute presentationCerebral infarctsCase presentationAFacial droopAntibiotic therapyRenal diseaseRare causePatient populationCase reportClassic presentationConclusionsThis caseEndovascular infectionBlood culturesMonoclonal gammopathy
2017
Mycobacterium goodii endocarditis following mitral valve ring annuloplasty
Parikh RB, Grant M. Mycobacterium goodii endocarditis following mitral valve ring annuloplasty. Annals Of Clinical Microbiology And Antimicrobials 2017, 16: 14. PMID: 28327156, PMCID: PMC5361780, DOI: 10.1186/s12941-017-0190-4.Peer-Reviewed Case Reports and Technical NotesMeSH KeywordsAgedAnti-Bacterial AgentsCluster AnalysisDNA, BacterialDNA, RibosomalEchocardiography, TransesophagealEndocarditis, BacterialHeartHumansMaleMitral Valve AnnuloplastyMycobacteriumMycobacterium Infections, NontuberculousPhylogenyRadiography, ThoracicReplantationRNA, Ribosomal, 16SSequence Analysis, DNATomography, X-Ray ComputedTreatment OutcomeConceptsMitral valve ring annuloplastyInfrequent human pathogenMitral valve replacementCombination of ciprofloxacinTrimethoprim/sulfamethoxazoleDrug susceptibility testingValve replacementCase presentationWeProsthetic infectionSuccessful treatmentDifferential diagnosisRing annuloplastyMicrobiologic laboratorySusceptibility testingEndocarditisPositive rodsInfectionDiagnosisHuman pathogensGene sequencingRDNA gene sequencingAnnuloplastyPatientsMolecular techniquesInjury