1999
Recombinant Vesicular Stomatitis Virus Expressing Respiratory Syncytial Virus (RSV) Glycoproteins: RSV Fusion Protein Can Mediate Infection and Cell Fusion
Kahn J, Schnell M, Buonocore L, Rose J. Recombinant Vesicular Stomatitis Virus Expressing Respiratory Syncytial Virus (RSV) Glycoproteins: RSV Fusion Protein Can Mediate Infection and Cell Fusion. Virology 1999, 254: 81-91. PMID: 9927576, DOI: 10.1006/viro.1998.9535.Peer-Reviewed Original ResearchMeSH KeywordsAmino Acid SequenceAnimalsBinding SitesCell LineCricetinaeCytoplasmGene ExpressionGenetic VectorsGlycoproteinsHN ProteinHumansMembrane FusionMolecular Sequence DataRecombinant Fusion ProteinsRespiratory Syncytial Virus, HumanTumor Cells, CulturedVesicular stomatitis Indiana virusViral Envelope ProteinsViral Fusion ProteinsViral ProteinsVirionConceptsRecombinant vesicular stomatitis virusVesicular stomatitis virusRSV fusion proteinRSV F glycoproteinRSV vaccineF recombinantsRSV glycoproteinsRSV proteinsEnvelope glycoproteinVirus attachmentFusion (F) envelope glycoproteinsF glycoproteinG glycoproteinStomatitis virusLarge syncytiaGlycoproteinPH-independent pathwayCell surfaceCell fusionCytoplasmic tail sequencesVSV G.Endosomal pHFusion activityVaccineFusion protein
1992
Intermonomer disulfide bonds impair the fusion activity of influenza virus hemagglutinin
Kemble G, Bodian D, Rosé J, Wilson I, White J. Intermonomer disulfide bonds impair the fusion activity of influenza virus hemagglutinin. Journal Of Virology 1992, 66: 4940-4950. PMID: 1629960, PMCID: PMC241339, DOI: 10.1128/jvi.66.8.4940-4950.1992.Peer-Reviewed Original ResearchAnimalsAntibodies, MonoclonalCell LineCHO CellsCricetinaeDisulfidesDithiothreitolErythrocytesFluorescent DyesHemagglutinin Glycoproteins, Influenza VirusHemagglutinins, ViralHumansHydrogen-Ion ConcentrationKineticsMacromolecular SubstancesMembrane FusionProtein ConformationRhodaminesViral Envelope Proteins
1991
Membrane fusion activity, oligomerization, and assembly of the rabies virus glycoprotein
Whitt M, Buonocor L, Prehaud C, Rose J. Membrane fusion activity, oligomerization, and assembly of the rabies virus glycoprotein. Virology 1991, 185: 681-688. PMID: 1660200, DOI: 10.1016/0042-6822(91)90539-n.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAntigens, ViralBase SequenceCell LineCentrifugation, Density GradientCricetinaeFlow CytometryGenetic Complementation TestGlycoproteinsHumansHydrogen-Ion ConcentrationKineticsMacromolecular SubstancesMembrane FusionMembrane GlycoproteinsMiceMolecular Sequence DataPlasmidsRabies virusRecombinant Fusion ProteinsVesicular stomatitis Indiana virusViral Envelope ProteinsViral Fusion ProteinsConceptsVSV G proteinG protein trimersMembrane fusion activityVirus G proteinG proteinsRabies G proteinFusion activityHybrid proteinProtein trimerVesicular stomatitis virus G proteinVirus glycoproteinRabies virus glycoproteinCytoplasmic domainMembrane fusionExtracellular domainHeLa cellsRabies virus G proteinCell surfaceProteinVSV particlesSucrose gradientsVSV infectivityGlycoproteinSpike glycoproteinChemical crosslinkingFatty acid acylation is not required for membrane fusion activity or glycoprotein assembly into VSV virions
Whitt M, Rose J. Fatty acid acylation is not required for membrane fusion activity or glycoprotein assembly into VSV virions. Virology 1991, 185: 875-878. PMID: 1660205, DOI: 10.1016/0042-6822(91)90563-q.Peer-Reviewed Original ResearchConceptsFatty acid acylationVSV G proteinMembrane fusion activityVesicular stomatitis virusG proteinsWild-type G proteinFusion activityWild-type proteinTemperature-sensitive mutantCytoplasmic domainTransient expressionPresence of palmitateVSV virionsIndiana serotypeHeLa cellsExpression of CSProteinStomatitis virusLife cycleSyncytium formationExpressionMutantsAcylationVirionsVirus
1990
A fusion-defective mutant of the vesicular stomatitis virus glycoprotein
Whitt M, Zagouras P, Crise B, Rose J. A fusion-defective mutant of the vesicular stomatitis virus glycoprotein. Journal Of Virology 1990, 64: 4907-4913. PMID: 2168975, PMCID: PMC247981, DOI: 10.1128/jvi.64.10.4907-4913.1990.Peer-Reviewed Original ResearchConceptsWild-type G proteinG proteinsMutant proteinsFusion activityMutant G proteinsFusion-defective mutantsAmino acids 117Vesicular stomatitis virus glycoproteinFormation of heterotrimersUncharged amino acidsTemperature-sensitive mutantNew glycosylation siteMutant glycoproteinsVesicular stomatitis virusGlycosylation sitesMembrane fusionRescue of virusVSV virionsExtracellular domainAmino acidsCell surfaceProteinVSV serotypesStomatitis virusMutants