1991
Insulin inhibits apolipoprotein B secretion in isolated human hepatocytes
Salhanick A, Schwartz S, Amatruda J. Insulin inhibits apolipoprotein B secretion in isolated human hepatocytes. Metabolism 1991, 40: 275-279. PMID: 2000040, DOI: 10.1016/0026-0495(91)90109-a.Peer-Reviewed Original ResearchMeSH KeywordsApolipoproteins BCell CountCell SeparationHumansInsulinLipoproteins, VLDLLiverRadioimmunoassayConceptsB secretionApo B secretionHuman hepatocytesApo B contentApolipoprotein B secretionInsulin-dependent inhibitionChronic insulin exposureEffect of insulinPresence of insulinHuman-derived hepatoma cell lineLiver specimensCollagenase dispersionApo BInsulin exposureHepatoma cell lineL insulinSerum-free mediumHuman hepaticInsulinSecretionInsulin controlPrimary culturesCell linesHepatocytesFurther investigation
1988
Insulin-Mimetic Effects of Vanadate in Primary Cultures of Rat Hepatocytes
Jackson T, Salhanick A, Sparks J, Sparks C, Bolognino M, Amatruda J. Insulin-Mimetic Effects of Vanadate in Primary Cultures of Rat Hepatocytes. Diabetes 1988, 37: 1234-1240. PMID: 3044889, DOI: 10.2337/diab.37.9.1234.Peer-Reviewed Original ResearchMeSH KeywordsAcetatesAnimalsApolipoproteins BCells, CulturedInsulinKineticsLeucineLipidsLiverMaleProtein BiosynthesisRatsRats, Inbred StrainsVanadatesConceptsApoB secretionIntracellular lipogenesisHepatic apolipoprotein B secretionPrimary culturesApolipoprotein B secretionTermination of actionEffect of insulinMedium accumulationInsulin-mimetic effectsB secretionEffect of vanadatePostreceptor levelInsulin actionRat hepatocytesInsulinIntracellular glycogen accumulationHepatic proteinsSecretionInsulin-mimetic agentsGlycogen accumulationMimics insulin actionApoB.LipogenesisHepatocytesInhibition
1986
Insulin effects on apolipoprotein B lipoprotein synthesis and secretion by primary cultures of rat hepatocytes
Sparks C, Sparks J, Bolognino M, Salhanick A, Strumph P, Amatruda J. Insulin effects on apolipoprotein B lipoprotein synthesis and secretion by primary cultures of rat hepatocytes. Metabolism 1986, 35: 1128-1136. PMID: 3537632, DOI: 10.1016/0026-0495(86)90026-0.Peer-Reviewed Original ResearchConceptsLipoprotein synthesisPostprandial insulin releasePrimary culturesHepatic lipoprotein secretionEffect of insulinApo B secretionLipoprotein metabolic pathwaysAddition of insulinApo B massMonoclonal radioimmunoassayInsulin concentrationsVLDL secretionMedia insulin concentrationsB secretionApolipoprotein BInsulin releaseLipid secretionLipoprotein secretionDensity lipoproteinLipid radioactivityPhysiologic concentrationsRat hepatocytesLipoprotein apoproteinsInsulinInsulin effect