Etienne Caron, PhD
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About
Titles
Assistant Professor
Biography
Dr. Caron is a Canadian scientist with a background in Biotechnology and Systems Immunology. He received his PhD from the University of Montreal and completed his education at ETH-Zürich in Switzerland under the guidance of Dr. Ruedi Aebersold. Dr. Caron is known for his international leadership and expertise in immunopeptidomics for the global analysis of MHC-associated peptides using mass spectrometry technologies. His scientific program has the potential to revolutionize the research on vaccine design, cancer immunotherapy, infectious and autoimmune diseases, including treatment of neurodegenerative diseases and aging.
Dr. Caron began his career as a Principal Investigator in 2018 at the University of Montreal, Canada, with the goal of making the field of immunopeptidomics as transformative as cancer genomics to create new paradigms in immunology & immunotherapy to improve patient care worldwide.
In 2023, Dr. Caron was recruited by the Yale Center for Immuno-Oncology (YCIO) and the Department of Immunobiology. He is also currently a member of the Yale Center for Infection and Immunity (CII), and the Yale Center for Systems and Engineering Immunology (CSEI).
Dr. Caron is co-founder and former chair (2015-2020) of the Human Immunopeptidome Project. He also co-founded the start-up Neomabs Biotechnologies Inc., with the goal of transforming the treatment of childhood leukemia through targeted immunotherapies. Dr. Caron has also provided distinctive services to the life sciences industry through numerous collaborations with companies such as Biognosys, ImmunXperts, CellCarta, Genentech, and Flagship Pioneering.
Appointments
Immunobiology
Assistant ProfessorPrimary
Other Departments & Organizations
Education & Training
- Postdoctoral Fellow
- ETH Zürich (2018)
- Postdoctoral Fellow
- EMBL Barcelona (2012)
- PhD
- University of Montreal (2011)
- Japan Society for the Promotion of Science (JSPS) Fellow
- University of Tokyo (2009)
- MSc
- University of Montreal (2005)
- BSc
- University of Sherbrooke (2001)
- B.Sc. Industrial work terms
- Shire Biochem (2001)
Research
Overview
Medical Subject Headings (MeSH)
Academic Achievements and Community Involvement
Links & Media
Media
Moving from genomics to immunopeptidomics surveillance
(A) World map illustrating the ambition of profiling immunopeptidomes across human populations using advanced immunopeptidomics technologies. A microfluidic device for automated sample preparation and a mass spectrometer for data acquisition are shown as representative examples of technologies that will be further developed. (B) Schematic of the workflow to identify immunopeptidomic signatures of disease susceptibility/resistance to stratify patients and help personalize mitigation strategies in future pandemics. SARS-CoV-2 is used for illustrating the concept. In this example, viral peptides are isolated at population-scale from plasma samples (patient cohorts). Fictive bar plot of HLA-I-allele-specific self peptides in different organs (patient #1) and population-scale quantitative digital maps of soluble HLA-associated SARS-CoV-2 peptides from plasma samples are illustrated.