2017
Multifunctional molecule ERp57: From cancer to neurodegenerative diseases
Hettinghouse A, Liu R, Liu C. Multifunctional molecule ERp57: From cancer to neurodegenerative diseases. Pharmacology & Therapeutics 2017, 181: 34-48. PMID: 28723413, PMCID: PMC5743601, DOI: 10.1016/j.pharmthera.2017.07.011.Peer-Reviewed Original ResearchConceptsProtein disulfide isomerase gene familyMultiple cellular localizationsEndoplasmic reticulum localizationDiverse pathological statesGene familyERp57 functionsProtein familyPDI familySubcellular compartmentsPhysiological processesCellular localizationMultifunctional memberERp57Aberrant functionalityNeurodegenerative diseasesTherapeutic developmentPathological statesFamilyLocalizationIsomeraseRedox activityAvailable knowledgeNumerous studiesHostExpression
2008
p204, a p200 family protein, as a multifunctional regulator of cell proliferation and differentiation
Luan Y, Lengyel P, Liu CJ. p204, a p200 family protein, as a multifunctional regulator of cell proliferation and differentiation. Cytokine & Growth Factor Reviews 2008, 19: 357-369. PMID: 19027346, PMCID: PMC4442486, DOI: 10.1016/j.cytogfr.2008.11.002.Peer-Reviewed Original ResearchConceptsP200-family proteinsFamily proteinsAmino acid-long C-terminal domainLong C-terminal domainTissue-specific transcription factorsCell proliferationInterferon-inducible p200 familyTissue differentiationC-terminal domainMurine memberRas proteinsSubcellular compartmentsTranscription factorsHuman proteinsMultifunctional regulatorHomologous mouseTarget proteinsProteinTarget activityDifferentiationP204ProliferationTumor growthImportant roleFamily