Using the epidemiology of critical limb ischemia to estimate the number of patients amenable to endovascular therapy
Fereydooni A, Gorecka J, Dardik A. Using the epidemiology of critical limb ischemia to estimate the number of patients amenable to endovascular therapy. Vascular Medicine 2019, 25: 78-87. PMID: 31621531, DOI: 10.1177/1358863x19878271.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsCritical limb ischemiaLimb ischemiaEndovascular therapyEarly risk factor modificationRisk factor modificationPeripheral artery diseaseHealth-related qualityPopulation-based studyNumber of patientsArtery diseaseClinical stageSmoking cessationFactor modificationEarly diagnosisEffective treatmentLimb lossIschemiaAdvanced stageHealth problemsPatientsSignificant mortalityTherapyEpidemiologyDiseasePainEndovascular Revascularization Incorporating Infrapopliteal Coronary Drug-Eluting Stents Improves Clinical Outcomes in Patients with Critical Limb Ischemia and Tissue Loss
Huntress LA, Fereydooni A, Dardik A, Nassiri N. Endovascular Revascularization Incorporating Infrapopliteal Coronary Drug-Eluting Stents Improves Clinical Outcomes in Patients with Critical Limb Ischemia and Tissue Loss. Annals Of Vascular Surgery 2019, 63: 234-240. PMID: 31563654, DOI: 10.1016/j.avsg.2019.07.011.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAmputation, SurgicalConstriction, PathologicCritical IllnessDrug-Eluting StentsEndovascular ProceduresFemaleHumansIschemiaMaleMiddle AgedPeripheral Arterial DiseasePopliteal ArteryProgression-Free SurvivalProsthesis DesignRetrospective StudiesRisk FactorsTime FactorsUnited StatesVascular PatencyWound HealingConceptsCritical limb ischemiaCoronary drug-eluting stentsDrug-eluting stentsWIfI scoreMajor amputationEndovascular revascularizationClinical outcomesTissue lossPrimary patencyLimb ischemiaMean ankle-brachial indexOne-year primary patencyOne-year survival rateAnkle-brachial indexLimb salvage rateMulti-institutional experienceLevel IA evidenceInfrapopliteal applicationRevascularization benefitTibial revascularizationCause mortalityFoot infectionsInfrapopliteal lesionsArterial atherosclerosisLesion recurrenceThe potential and limitations of induced pluripotent stem cells to achieve wound healing
Gorecka J, Kostiuk V, Fereydooni A, Gonzalez L, Luo J, Dash B, Isaji T, Ono S, Liu S, Lee SR, Xu J, Liu J, Taniguchi R, Yastula B, Hsia HC, Qyang Y, Dardik A. The potential and limitations of induced pluripotent stem cells to achieve wound healing. Stem Cell Research & Therapy 2019, 10: 87. PMID: 30867069, PMCID: PMC6416973, DOI: 10.1186/s13287-019-1185-1.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsChronic woundsCell therapyStem cellsDiabetic foot ulcersCell typesWound healingInvasive harvesting techniquesAdult-derived stem cellsNormal skin architecturePluripotent stem cellsLimb ischemiaFoot ulcersLimited cell survivalSafety profileOnly cell typeAnimal modelsHuman studiesPotential treatmentPhysiologic responsesHealthy skinImmune rejectionAdvanced therapiesTranslational potentialUse of iPSCsSystemic factors