Scott Woods, MD
Elizabeth Mears and House Jameson Professor of PsychiatryCards
Appointments
Psychiatry
Primary
Child Study Center
Secondary
Contact Info
About
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Titles
Elizabeth Mears and House Jameson Professor of Psychiatry
Biography
Dr. Woods assesses young people at risk for psychosis through his PRIME Clinic, which also offers studies aiming to improve treatment for current symptoms and preventing progression.
Last Updated on April 07, 2025.
Appointments
Psychiatry
ProfessorPrimaryChild Study Center
ProfessorSecondary
Other Departments & Organizations
- Adult Psychiatry
- Child Study Center
- Connecticut Mental Health Center
- MR Core
- PRIME Psychosis Prodrome Research Clinic
- Psychiatry
- Yale Medicine
- Yale New Haven Health System
- Yale Ventures
Education & Training
- Resident
- Massachusetts General Hospital (1984)
- MD
- Baylor College of Medicine (1978)
Research
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Overview
Predictors and Mechanisms of Conversion to Psychosis (MH082022)
Aspirin vs placebo for the psychosis prodrome
D-serine for the psychosis prodrome (MH074356)
Dutetrabenzine for tardive dyskinesia
Huperzine for cognitive enhancement in schizophrenia (MH083436)
Medical Research Interests
Adolescent Psychiatry; Prodromal Symptoms; Psychiatry; Psychotic Disorders
ORCID
0000-0002-3103-5228
Research at a Glance
Yale Co-Authors
Frequent collaborators of Scott Woods's published research.
Publications Timeline
A big-picture view of Scott Woods's research output by year.
Research Interests
Research topics Scott Woods is interested in exploring.
Tyrone Cannon
Albert Powers, MD, PhD
Philip Corlett, PhD
Godfrey Pearlson, MA, MBBS
Zailyn Tamayo
Emily Farina, PhD
102Publications
599Citations
Psychotic Disorders
Prodromal Symptoms
Publications
2026
286. Schizophrenia Polygenic Risk, Deviations From Typical Brain Development, and Expected Brain Deficit Patterns in Individuals With Schizophrenia, Unaffected Relatives, and Healthy Controls
Karalis J, Chavannes A, Zhu J, Trevorrow Z, Ferreira-Ianone S, Nuechterlein K, Asarnow R, Addington J, Cadenhead K, Cannon T, Cornblatt B, Keshavan M, Mathalon D, Perkins D, Stone W, Tsuang M, Walker E, Woods S, Narr K, McEwen S, Ophoff R, Consortium N, Bearden C, Forsyth J. 286. Schizophrenia Polygenic Risk, Deviations From Typical Brain Development, and Expected Brain Deficit Patterns in Individuals With Schizophrenia, Unaffected Relatives, and Healthy Controls. Biological Psychiatry 2026, 99: s222. DOI: 10.1016/j.biopsych.2026.03.520.Peer-Reviewed Original Research746. Distinct Pathways From Early Adversity to Poor Functioning in High-Risk Youth: The Roles of MMN and Neurocognition
Carrion R, Dorvil S, Auther A, McLaughlin D, Ku B, Bachman P, Belger A, Duncan E, Hamilton H, Johannesen J, Light G, Niznikiewicz M, Roach B, Addington J, Bearden C, Cadenhead K, Cannon T, Keshavan M, Perkins D, Stone W, Walker E, Woods S, Mathalon D. 746. Distinct Pathways From Early Adversity to Poor Functioning in High-Risk Youth: The Roles of MMN and Neurocognition. Biological Psychiatry 2026, 99: s417-s418. DOI: 10.1016/j.biopsych.2026.03.980.Peer-Reviewed Original Research664. Social Daily Stress, Epigenetic Age Acceleration, and Conversion to Psychosis Among Adolescents at Clinical High Risk for Psychosis
Ku B, Xu Y, Arrant E, Addington J, Bearden C, Cadenhead K, Cannon T, Carrion R, Keshavan M, Mathalon D, Stone W, Woods S, Walker E, Perkins D, Huels A, Bozack A. 664. Social Daily Stress, Epigenetic Age Acceleration, and Conversion to Psychosis Among Adolescents at Clinical High Risk for Psychosis. Biological Psychiatry 2026, 99: s384. DOI: 10.1016/j.biopsych.2026.03.898.Peer-Reviewed Original Research2. Mapping the Pathway From Neurocognition to Functioning in Youth at Clinical High Risk for Psychosis: Distinct Associations With Functional Capacity and Social Engagement
Ma R, Carrión R, Cornblatt B, Addington J, Cadenhead K, Cannon T, Keshavan M, Mathalon D, Perkins D, Stone W, Tsuang M, Walker E, Woods S, Bearden C. 2. Mapping the Pathway From Neurocognition to Functioning in Youth at Clinical High Risk for Psychosis: Distinct Associations With Functional Capacity and Social Engagement. Biological Psychiatry 2026, 99: s75-s76. DOI: 10.1016/j.biopsych.2026.03.182.Peer-Reviewed Original ResearchCannabis and Tobacco Co-Use Predicts Psychosis in Clinical High Risk Cohorts
Bello D, Blyth S, Rabin R, Addington J, Bearden C, Cadenhead K, Cannon T, Carrión R, Cornblatt B, Keshavan M, Mathalon D, Perkins D, Seidman L, Stone W, Tsuang M, Walker E, Woods S, Brady R, Ward H. Cannabis and Tobacco Co-Use Predicts Psychosis in Clinical High Risk Cohorts. Biological Psychiatry 2026, 99: s72. DOI: 10.1016/j.biopsych.2026.03.176.Peer-Reviewed Original ResearchAltmetricBiophysical modeling of excitation/inhibition balance and conversion to psychosis in the clinical high risk syndrome
Rodriguez-Sanchez J, Hauke D, Pinotsis D, Berndt L, Oloye H, Nicholas S, Hamilton H, Roach B, Bachman P, Belger A, Carrión R, Duncan E, Johannesen J, Light G, Niznikiewicz M, Friston K, Addington J, Bearden C, Cadenhead K, Perkins D, Walker E, Woods S, Cannon T, Adams R, Mathalon D. Biophysical modeling of excitation/inhibition balance and conversion to psychosis in the clinical high risk syndrome. Biological Psychiatry 2026 PMID: 42025866, DOI: 10.1016/j.biopsych.2026.04.007.Peer-Reviewed Original ResearchCitationsAltmetricCannabis and Tobacco Co-Use is Associated with Impaired Neurocognitive Performance in Individuals at Clinical High Risk for Psychosis
Bello D, Connolly J, Addington J, Bearden C, Cadenhead K, Cannon T, Cornblatt B, Keshavan M, Mathalon D, Perkins D, Seidman L, Stone W, Tsuang M, Walker E, Woods S, Brady R, Carrión R, Ward H. Cannabis and Tobacco Co-Use is Associated with Impaired Neurocognitive Performance in Individuals at Clinical High Risk for Psychosis. Biological Psychiatry Cognitive Neuroscience And Neuroimaging 2026 PMID: 41999882, DOI: 10.1016/j.bpsc.2026.03.021.Peer-Reviewed Original ResearchCorrelation networks of blood proteins in the neuroimmunology of schizophrenia—replication and extension
Jeffries C, Bizon C, Ford J, Addington J, Bearden C, Cadenhead K, Cannon T, Cornblatt B, Keshavan M, Mathalon D, Seidman L, Stone W, Walker E, Woods S, Perkins D. Correlation networks of blood proteins in the neuroimmunology of schizophrenia—replication and extension. Translational Psychiatry 2026 PMID: 41965717, DOI: 10.1038/s41398-026-03934-6.Peer-Reviewed Original ResearchSocial withdrawal and hippocampal volume among adolescents at clinical high risk for psychosis and healthy comparisons: The moderating role of neighborhood residential stability
Ku B, Arrant E, Yuan Q, Aberizk K, Addington J, Bearden C, Cadenhead K, Cannon T, Carrión R, Keshavan M, Mathalon D, Perkins D, Stone W, Woods S, Walker E. Social withdrawal and hippocampal volume among adolescents at clinical high risk for psychosis and healthy comparisons: The moderating role of neighborhood residential stability. Schizophrenia Research 2026, 293: 81-90. PMID: 41955767, PMCID: PMC13094779, DOI: 10.1016/j.schres.2026.03.024.Peer-Reviewed Original ResearchConceptsClinical high riskSocial withdrawalHippocampal volumeNeighborhood residential stabilityHealthy comparisonNorth American Prodrome Longitudinal Study Phase 2Premorbid Adjustment ScaleModerating RoleResidential stabilityPsychiatric vulnerabilityAdjustment ScaleAssociated with HVCHR-PContextual factorsNeurodevelopmental vulnerabilityPsychosisIntervention effortsBehavioral risk factorsBilateral HVCross-sectional associationsHigh riskFollow-up modelWithdrawalStudy phase 2AdolescentsNeighborhood social fragmentation and cerebello-thalamo-cortical connectivity in youth at clinical high-risk for psychosis and healthy comparisons
Ku B, Arrant E, Addington J, Bearden C, Cadenhead K, Cannon T, Carrion R, Keshavan M, Mathalon D, Stone W, Woods S, Walker E, Perkins D, Cao H. Neighborhood social fragmentation and cerebello-thalamo-cortical connectivity in youth at clinical high-risk for psychosis and healthy comparisons. Brain And Environment 2026, 5: 100016. PMID: 41907310, PMCID: PMC13030900, DOI: 10.1016/j.braen.2026.100016.Peer-Reviewed Original ResearchCitationsAltmetricConceptsNeighbourhood social fragmentationClinical high riskHealthy comparisonCHR-PSocial fragmentationPsychosis riskNorth American Prodrome Longitudinal Study Phase 2Functional connectivity dataPredictive coding frameworkCerebello-thalamo-cortical connectionsHC youthPsychosisIndividual povertyMaladaptive processesBrain's abilitySocial tiesBelief updatingEducational attainmentSocial worldConnectivity dataYouthStudy phase 2Early interventionNeighborhoodSocial environment
Clinical Trials
Current Trials
ProNET
IRB ID2000029159RolePrincipal InvestigatorPrimary Completion Date12/31/2024Recruiting ParticipantsSchizophrenia Spectrum Biomarkers Consortium (SSBC)
IRB ID2000029485RoleSub InvestigatorPrimary Completion Date12/31/2030Recruiting ParticipantsStudy of Brain Function Across the Lifespan
IRB ID2000020891RoleSub InvestigatorPrimary Completion Date07/31/2022Recruiting ParticipantsGenderBothAge18 years - 65 yearsSleep Dependent Learning in Schizophrenia and Psychosis Risk Syndrome
IRB ID1201009524RoleSub InvestigatorPrimary Completion Date01/31/2022Recruiting ParticipantsGenderBothAge18 years - 55 years
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News
- May 20, 2026
Hyman Awarded 2026 Yale Department of Psychiatry Mental Health Advocacy Award
- April 08, 2026
Yale-NAMI Conference on Neuroscience, Mental Health and Society Scheduled for May 9
- March 23, 2026
Powers Honored with SIRS Research Excellence Award
- February 17, 2026
Yale Psychiatry Ranks Second in Nation in NIH Research Funding
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Psychiatry
300 George St
New Haven, CT 06511-
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