Catalina Mourgues-Codern
Associate Research Scientist in PsychiatryCards
About
Research
Publications
2026
Stepped care for young people at clinical high risk for psychosis: a real-world study
Broekhuijse A, Saxena A, Walsh B, Mourgues-Codern C, Mukhtar H, Howard S, Woods SW, Powers AR, Farina EA. Stepped care for young people at clinical high risk for psychosis: a real-world study. 2026 DOI: 10.64898/2026.02.05.26345683.Peer-Reviewed Original Research In Press
2025
Instruments for assessing insight in psychosis: A systematic review of psychometric properties
Hazan H, Tayfur S, Karmani S, Gibbs-Dean T, Mourgues C, Srihari V. Instruments for assessing insight in psychosis: A systematic review of psychometric properties. Psychological Medicine 2025, 55: e362. PMID: 41292267, PMCID: PMC12671917, DOI: 10.1017/s0033291725101918.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsThis study investigates tools for assessing insight in psychosis, finding most scales reliable but highlighting the need for culturally adaptive, multidimensional measures for better clinical and research utility.Shift in sex and age of individuals at a clinical high risk (CHR) for psychosis: relation to differences in recruitment methods and effect on sample characteristics
Farina E, Mourgues-Codern C, Stimler K, Kenney J, Saxena A, Mukhtar H, Addington J, Bearden C, Cadenhead K, Cannon T, Cornblatt B, Ellman L, Gold J, Keshavan M, Mathalon D, Mittal V, Perkins D, Schiffman J, Silverstein S, Strauss G, Stone W, Walker E, Waltz J, Corlett P, Powers A, Woods S. Shift in sex and age of individuals at a clinical high risk (CHR) for psychosis: relation to differences in recruitment methods and effect on sample characteristics. Schizophrenia 2025, 11: 123. PMID: 41053030, PMCID: PMC12501016, DOI: 10.1038/s41537-025-00663-5.Peer-Reviewed Original ResearchClinical high riskClinical high-risk samplesNorth American Prodrome Longitudinal StudyOvert psychotic disordersSample characteristicsSample of individualsNegative symptomsPsychotic disordersPsychosis riskSelf-referralRecruitment sourcesBetween-study differencesComputerized assessmentHierarchical regressionPsychosisRecruitment source effectsClinical implicationsLongitudinal studyGeneral symptomsDemographic differencesClinical profileSymptomsParticipantsClinical heterogeneitySexSample ascertainment and clinical outcome measures in the Accelerating Medicines Partnership® Schizophrenia Program
Addington J, Liu L, Braun A, Auther A, Calkins M, Cornblatt B, Corcoran C, Fusar-Poli P, Kerr M, Mourgues-Codern C, Nunez A, Oliver D, Strauss G, Walsh B, Alameda L, Arango C, Breitborde N, Broome M, Cadenhead K, Carrion R, Chen E, Choi J, Coleman M, Conus P, Diaz-Caneja C, Dwyer D, Ellman L, Faghankhani M, Gaspar P, Gerber C, Glenthøj L, Horton L, Hui C, Jacobs G, Kambeitz J, Kambeitz-Ilankovic L, Keshavan M, Kim S, Koutsouleris N, Kwon J, Langbein K, Lewandowski K, Mamah D, Marcy P, Mathalon D, Mittal V, Nordentoft M, Pearlson G, Penzel N, Perez J, Perkins D, Powers A, Rogers J, Sabb F, Schiffman J, Shah J, Silverstein S, Smesny S, Stone W, Thompson A, Thompson J, Upthegrove R, Verma S, Wang J, Wastler H, Wickham A, Rossum I, Wolf D, Bouix S, Pasternak O, Kahn R, Bearden C, Kane J, McGorry P, Buccilli K, Nelson B, Shenton M, Woods S, Yung A. Sample ascertainment and clinical outcome measures in the Accelerating Medicines Partnership® Schizophrenia Program. Schizophrenia 2025, 11: 54. PMID: 40180953, PMCID: PMC11968923, DOI: 10.1038/s41537-025-00556-7.Peer-Reviewed Original ResearchMultisite studyClinical measuresAssessment protocolTraining of clinical staffSchizophrenia ProgramClinical ratingsClinical ascertainmentExpert clinical inputClinical assessment protocolResearch NetworkNative languageClinical outcome measuresReporting of clinical dataClinical staffSample ascertainmentClinical trainingAscertainment criteriaOutcome measuresAscertainmentClinical assessmentMeasurement teamObservational studyClinical inputCoordinating CenterSchizophreniaEmergence and Dynamics of Delusions and Hallucinations Across Stages in Early Psychosis
Mourgues-Codern C, Benrimoh D, Gandhi J, Farina E, Vin R, Zamorano T, Parekh D, Malla A, Joober R, Lepage M, Iyer S, Addington J, Bearden C, Cadenhead K, Cornblatt B, Keshavan M, Stone W, Mathalon D, Perkins D, Walker E, Cannon T, Woods S, Shah J, Powers A. Emergence and Dynamics of Delusions and Hallucinations Across Stages in Early Psychosis. Biological Psychiatry 2025, 98: 679-688. PMID: 40020853, PMCID: PMC12353309, DOI: 10.1016/j.biopsych.2025.02.891.Peer-Reviewed Original ResearchFirst-episode psychosis patientsSymptom patternsNorth American Prodrome Longitudinal StudyPositive symptoms of psychosisSymptoms of psychosisCHR-P samplesEarly intervention programsPositive symptomsDelusional ideationPsychosis patientsEarly psychosisCHR-PNeural mechanismsDelusionsHallucination onsetHallucinationsPsychosisBaseline assessmentLongitudinal studyIntervention programsSymptomsTime courseParticipantsIdeationOnsetBaseline Clinical Characterization of Participants in the Accelerating Medicines Partnership Schizophrenia Program
Addington J, Liu L, Chu M, Jungert K, Penzel N, Pasternak O, Farina E, Carrion R, Corcoran C, Mittal V, Strauss G, Yung A, Alameda L, Arango C, Borders O, Bouix S, Breitborde N, Broome M, Cadenhead K, Castillo-Passi R, Chen E, Choi J, Coleman M, Conus P, Diaz-Caneja C, Ellman L, Poli P, Gaspar P, Gerber C, Glenthøj L, Horton L, Hui C, Kambeitz J, Kambeitz-Ilankovic L, Kapur T, Kelly S, Kerr M, Keshavan M, Kim M, Kim S, Koutsouleris N, Kwon J, Langbein K, Lewandowski K, Mamah D, Marcy P, Mathalon D, Mourgues C, Nordentoft M, Nunez A, Pearlson G, Perez J, Perkins D, Powers A, Rogers J, Sabb F, Schiffman J, Seitz-Holland J, Shah J, Silverstein S, Smesny S, Stone W, Thompson J, Upthegrove R, Verma S, Wang J, Wolf D, Zhang T, Addamo L, Buccilli K, Dwyer D, Todd S, Cho Y, Fontenau C, Tamayo Z, Bearden C, Kane J, McGorry P, Kahn R, Shenton M, Woods S, Barnaby A, Calkins M. Baseline Clinical Characterization of Participants in the Accelerating Medicines Partnership Schizophrenia Program. Schizophrenia Bulletin Open 2025, 6: sgaf012. PMID: 40861307, PMCID: PMC12377803, DOI: 10.1093/schizbullopen/sgaf012.Peer-Reviewed Original ResearchClinical high riskCommunity controlsClinical high-risk individualsClinical high-risk participantsClinical high-risk criteriaClinical high-risk populationsPsychosis-Risk SyndromesClinical measuresNegative symptomsPositive symptomsPsychosis-riskPsychotic symptomsDSM-5Characterization of participantsSchizophrenia ProgramClinical variablesSuicidal ideationDiagnostic criteriaSubstance useSeverity ratingsComprehensive assessmentStructured interviewsPsychosisPreliminary natureAt-riskSample Ascertainment and Recruitment Sources in the Accelerating Medicines Partnership Schizophrenia Program
Addington J, Shalev A, Liu L, Jahraus C, Chu M, Farina E, Poli P, Marcy P, Nunez A, Calkins M, Alameda L, Arango C, Borders O, Bouix S, Breitborde N, Broome M, Cadenhead K, Carrion R, Castillo-Passi R, Chen E, Choi J, Coleman M, Conus P, Corcoran C, Diaz-Caneja C, Ellman L, Gaspar P, Gerber C, Glenthøj L, Horton L, Hui C, Kambeitz J, Kambeitz-Ilankovic L, Kapur T, Kelly S, Kerr M, Keshavan M, Kim M, Kim S, Koutsouleris N, Kwon J, Langbein K, Lewandowski K, Mamah D, Mathalon D, Mittal V, Mourgues C, Nordentoft M, Pasternak O, Pearlson G, Penzel N, Perez J, Perkins D, Powers A, Rogers J, Sabb F, Schiffman J, Seitz-Holland J, Shah J, Silverstein S, Smesny S, Stone W, Strauss G, Thompson J, Upthegrove R, Verma S, Wang J, Wolf D, Yung A, Zhang T, Addamo L, Buccilli K, Todd S, Dwyer D, Bearden C, Kane J, McGorry P, Kahn R, Shenton M, Woods S, Barnaby A. Sample Ascertainment and Recruitment Sources in the Accelerating Medicines Partnership Schizophrenia Program. Schizophrenia Bulletin Open 2025, 6: sgaf013. PMID: 40861306, PMCID: PMC12377801, DOI: 10.1093/schizbullopen/sgaf013.Peer-Reviewed Original ResearchClinical high riskSelf-referralRecruitment sourcesCommunity controlsAdult community mental health servicesCommunity mental health servicesMental health servicesSocial functioningHelp-seeking behaviorSelf-referred individualsLevel of functionHealthcare providersHealth servicesSample ascertainmentClinical high-risk participantsClinical high-risk criteriaClinical high-risk researchComprehensive assessmentSchizophrenia ProgramCommunity agenciesPsychiatric hospitalSevere APAt-riskOutreach effortsRecruitment group
2024
A Computational Account of the Development and Evolution of Psychotic Symptoms
Powers A, Angelos P, Bond A, Farina E, Fredericks C, Gandhi J, Greenwald M, Hernandez-Busot G, Hosein G, Kelley M, Mourgues C, Palmer W, Rodriguez-Sanchez J, Seabury R, Toribio S, Vin R, Weleff J, Woods S, Benrimoh D. A Computational Account of the Development and Evolution of Psychotic Symptoms. Biological Psychiatry 2024, 97: 117-127. PMID: 39260466, PMCID: PMC11634669, DOI: 10.1016/j.biopsych.2024.08.026.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsPsychotic symptomsSymptom formationEmergence of psychotic symptomsConversion to psychosisPrediction error signalsIncoming sensory informationHallucination severityDiminished signal-to-noise ratioComputational accountPsychiatric interventionNeural systemsHallucinationsIncreasing convictionOver-reliancePsychosisSensory informationLongitudinal developmentSymptomsBelief formationRecent social stress and severity of auditory hallucinations
Farina E, Mourgues-Codern C, Sibarium E, Powers A. Recent social stress and severity of auditory hallucinations. Schizophrenia Research 2024, 269: 64-70. PMID: 38733801, PMCID: PMC11180583, DOI: 10.1016/j.schres.2024.04.024.Peer-Reviewed Original ResearchHearing voicesVoice-hearersAuditory verbal hallucinationsNon-clinical voice-hearersCross-sectional designSocial stressDepressive symptom severitySelf-reported aspectsPsychosocial interventionsAuditory hallucinationsClinical distressAdverse social experiencesHearingSeverity of auditory hallucinationsAdministered self-report measuresRecent stressMedication-resistant auditory verbal hallucinationsDistressRelational demographicsDaily social stressRegression modelsSocial stressorsSymptom severityAuditory experienceHallucination severity
2023
Evidence for Reduced Sensory Precision and Increased Reliance on Priors in Hallucination-Prone Individuals in a General Population Sample
Benrimoh D, Fisher V, Seabury R, Sibarium E, Mourgues C, Chen D, Powers A. Evidence for Reduced Sensory Precision and Increased Reliance on Priors in Hallucination-Prone Individuals in a General Population Sample. Schizophrenia Bulletin 2023, 50: 349-362. PMID: 37830405, PMCID: PMC10919780, DOI: 10.1093/schbul/sbad136.Peer-Reviewed Original ResearchSensory evidenceSensory precisionHallucinatory experiencesHallucination severityCH rateHallucination-prone individualsIncoming sensory evidencePrior weightingLinguistic versionsGaussian filter modelNonlinguistic stimuliPerceptual inferencePerceptual statesPerceptual beliefsResponse confidenceAuditory informationTask behaviorGeneral population sampleOnline sampleAuditory hallucinationsGeneral population participantsStimuliPast resultsParticipantsTask