2025
The Significance of Mothers’ Neural Responding to Infant Emotional Cues for Caregiving Behaviors: The Moderating Role of Infant Temperamental Distress
Patrick M, Xu N, Rutherford H, Groh A. The Significance of Mothers’ Neural Responding to Infant Emotional Cues for Caregiving Behaviors: The Moderating Role of Infant Temperamental Distress. Developmental Psychology 2025, 61: 1384-1396. PMID: 39786797, PMCID: PMC12202177, DOI: 10.1037/dev0001852.Peer-Reviewed Original ResearchSensitivity to distressInfant emotional expressionsCaregiving behaviorInfant distressEmotional expressionMaternal sensitivity to distressInfant's emotional cuesModerating RoleMothers' intrusivenessMaternal sensitivityEmotional cuesMothers' reportsInfant expressionsN170Facial encodingDistressP300CaregiversTemperamentNondistressBehaviorCuesMothersAssociationInfantsLate Permissive Hypercapnia for Mechanically Ventilated Preterm Infants: A Randomized Trial
Travers C, Gentle S, Shukla V, Aban I, Yee A, Armstead K, Benz R, Laney D, Ambalavanan N, Carlo W. Late Permissive Hypercapnia for Mechanically Ventilated Preterm Infants: A Randomized Trial. Pediatric Pulmonology 2025, 60: e71165. PMID: 40525736, PMCID: PMC12172392, DOI: 10.1002/ppul.71165.Peer-Reviewed Original ResearchConceptsPostnatal day 7Permissive hypercapniaPreterm infantsInstitutional review boardDay 7Ventilator-freeMechanically ventilated preterm infantsSingle-center randomized clinical trialReduced mechanical ventilation durationWeeks postmenstrual ageMechanical ventilation durationRespiratory distress syndromeVentilator-free daysRandomized clinical trialsPostmenstrual ageGestational ageWeeks gestationDistress syndromeVentilation durationBirth weightLung protectionRandomized trialsClinical trialsPrimary outcomeInfantsRisk of Bacterial Infections in Febrile Infants 61 to 90 Days Old With Respiratory Viruses.
Aronson P, Mahajan P, Nielsen B, Olsen C, Meeks H, Grundmeier R, Kuppermann N. Risk of Bacterial Infections in Febrile Infants 61 to 90 Days Old With Respiratory Viruses. 2025, 156 PMID: 40506050, DOI: 10.1542/peds.2025-070617.Peer-Reviewed Original ResearchConceptsPrevalence of urinary tract infectionUrinary tract infectionPediatric Emergency Care Applied Research NetworkRespiratory viral testingRespiratory viral infectionsFebrile infantsBacterial meningitisRespiratory virusesSARS-CoV-2Viral testingViral infectionSARS-CoV-2-positive infantsBacterial infectionsRisk of bacterial infectionPrevalence of bacteremiaPrevalence of bacterial infectionRespiratory syncytial virusBlood culturesTract infectionsPositive infantsSyncytial virusNegative infantsBacteremiaMeningitisInfantsCovert attention modulates the SSVEP in a paradigm suitable for infants and young children
Ganea N, Aslin R, Lewkowicz D. Covert attention modulates the SSVEP in a paradigm suitable for infants and young children. Attention, Perception, & Psychophysics 2025, 1-20. PMID: 40474052, DOI: 10.3758/s13414-025-03097-4.Peer-Reviewed Original ResearchCovert attentionIntertrial coherenceMeasures of attentional modulationYoung childrenCentral stimulusShifts of covert attentionOvert attentionSignal-to-noise ratioResponse epochsVisual stimuliSSVEP responsesCentral gazeInfantsAttention modulePeripheral stimuliPeripheral visual fieldVisual gazeStimuliSignificant attenuationFlickering visual stimuliVisual fieldGazeParadigmPeripheral eventsChildrenEcological Momentary Assessment Reveals Causal Effects of Music Enrichment on Infant Mood
Cho E, Yurdum L, Ebinne E, Hilton C, Lai E, Bertolo M, Brown P, Milosh B, Sened H, Tamir D, Mehr S. Ecological Momentary Assessment Reveals Causal Effects of Music Enrichment on Infant Mood. Child Development 2025, 96: 1555-1567. PMID: 40432545, PMCID: PMC12208017, DOI: 10.1111/cdev.14246.Peer-Reviewed Original ResearchConceptsInfant-directed singingEcological momentary assessmentEnrichment interventionsMusical enrichmentParental singingPost-intervention improvementsMusicSingingCaregiver moodImprove healthMomentary assessmentCausal effectsLong-term effectsRandomized trialsMoodInterventionHuman infancyLonger-termHealthInfantsInfant moodTrialsParentsGenetic Associations of Blink Behavior in Infants and Toddlers: A Computer Vision Approach
Bae Y, Li B, Dommer K, Reninger M, Hegerberg K, Ajwani A, Falck-Ytter T, Shic F. Genetic Associations of Blink Behavior in Infants and Toddlers: A Computer Vision Approach. 2025, 1-6. DOI: 10.1145/3715669.3726903.Peer-Reviewed Original ResearchBlink detectionComputer vision approachesFacial landmarksVision approachEfficientNet-B4Toddlers' attentionGenetic influencesGaze patternsChildren faceSocial communicationEye trackingDizygotic twinsHead orientationBlink rateBlink measuresComputerGenetic contributionAge predictionStrong associationsRetinaFaceBlinkInfantsIntrinsic characteristicsThe ubiquity of episodic-like memory during infancy
Behm L, Turk-Browne N, Kibbe M. The ubiquity of episodic-like memory during infancy. Trends In Cognitive Sciences 2025 PMID: 40404529, DOI: 10.1016/j.tics.2025.04.003.Peer-Reviewed Original ResearchPoor surgical outcomes following Paenibacillus infant infectious hydrocephalus.
Ericson J, Natukwatsa D, Ssenyonga P, Onen J, Mugamba J, Mulondo R, Morton S, Movassagh M, Templeton K, Hehnly C, Mbabazi-Kabachelor E, Kulkarni A, Warf B, Broach J, Paulson J, Schiff S. Poor surgical outcomes following Paenibacillus infant infectious hydrocephalus. Journal Of Neurosurgery Pediatrics 2025, 1-12. PMID: 40378477, PMCID: PMC12211056, DOI: 10.3171/2025.1.peds24254.Peer-Reviewed Original ResearchPostinfectious hydrocephalusPP patientsPN patientsEndoscopic diversionHydrocephalus surgeryPositive CSF polymerase chain reactionPrimary outcomeMedian follow-up periodCSF polymerase chain reactionFailure-free survivalPoor surgical outcomesPrimary event rateFollow-up periodOverall survivalCSF diversionHydrocephalic infantsSurgical outcomesNeurosurgical evaluationPolymerase chain reactionCompare outcomesSecondary outcomesPatientsEvent ratesInfantsChain reactionThe shifting landscape of the preterm brain
Kratimenos P, Sanidas G, Simonti G, Byrd C, Gallo V. The shifting landscape of the preterm brain. Neuron 2025 PMID: 40239653, DOI: 10.1016/j.neuron.2025.03.024.Peer-Reviewed Original ResearchPreterm infantsGestational ageLong-term outcomes of preterm infantsLong-term neurodevelopmental consequencesOutcomes of preterm infantsPreterm brain injuryLong-term outcomesPreterm birth complicationsInvestigate therapeutic strategiesPreterm brainPreterm birthHypoxia-ischemiaIntracranial hemorrhageNeonatal careImpaired brain functionGlobal health concernPretermBirth complicationsOligodendrocyte injuryNon-pharmacological approachesUtero developmentTherapeutic strategiesSurvival rateInfantsBirth persistThe Science of Neurohabilitation and Neurodevelopmental Care for Infants with High-Risk Neonatal Illnesses
Erdei C, Gallo V, Maitre N, Spittle A, Inder T. The Science of Neurohabilitation and Neurodevelopmental Care for Infants with High-Risk Neonatal Illnesses. The Journal Of Pediatrics 2025, 282: 114582. PMID: 40221018, DOI: 10.1016/j.jpeds.2025.114582.Peer-Reviewed Original ResearchSupine (Back) Sleep Position
Colvin B, Colson E. Supine (Back) Sleep Position. 2025, 169-187. DOI: 10.1007/978-3-031-84294-8_8.Peer-Reviewed Original ResearchPost-discharge nutrition to optimize preterm infant short- and long-term outcomes
Taylor S, Buck C. Post-discharge nutrition to optimize preterm infant short- and long-term outcomes. Seminars In Fetal And Neonatal Medicine 2025, 30: 101637. PMID: 40246652, DOI: 10.1016/j.siny.2025.101637.Peer-Reviewed Original ResearchConceptsPost-discharge nutritionLong-term outcomesPreterm infantsDegree of preterm birthVery preterm infantsMaternal milk feedingInfant growth patternsHealthy growth patternsDevelopment of obesityInfant short-Preterm birthFetal nutritionClinical trialsNutritional deficitsBody compositionLong-term healthMilk feedingDeliver individualized careGrowth patternPost-hospital dischargeSupplemental nutritionNutritional supplementsPretermInfantsNeurodevelopmental difficultiesSex-differences in Mothers' own milk and neurodevelopmental outcomes in preterm infants
Zhao T, Li A, Chang X, Xu W, Quinn T, Chen J, Matson A, Chen M, Taylor S, Cong X. Sex-differences in Mothers' own milk and neurodevelopmental outcomes in preterm infants. Frontiers In Pediatrics 2025, 13: 1523952. PMID: 40224385, PMCID: PMC11985779, DOI: 10.3389/fped.2025.1523952.Peer-Reviewed Original ResearchMother's own milkNICU Network Neurobehavioral ScalePreterm infantsYears of corrected ageBayley Scales of Infant and Toddler DevelopmentGrowth z scoresHuman donor milkNeurodevelopmental outcomesSex-differential associationNeurobehavioral ScaleBayley ScalesCohort studyDonor milkRisk predictorsWeek 8PretermYear of CAZ-scoreToddler DevelopmentNICUWeek 9InfantsFeeding regimensRegimensNeurodevelopmentAlterations in infant adipokine concentrations in the first postnatal week with exposure to diabetes in pregnancy
Borden C, Shabanova V, Taylor S, Buck C. Alterations in infant adipokine concentrations in the first postnatal week with exposure to diabetes in pregnancy. Journal Of Perinatology 2025, 45: 622-627. PMID: 40121331, DOI: 10.1038/s41372-025-02269-2.Peer-Reviewed Original ResearchPostnatal weekPreterm infantsExposed to diabetesMetabolic hormonesNon-DM groupExposure to diabetesEarly postnatal periodHigher leptinLower ghrelinInfant bloodTerm groupDM groupProspective cohortAdipokine concentrationsPostnatal periodEarly alterationsHormone concentrationsInfantsPretermHormonePrematurityPregnancyGhrelinLeptinResistinFeeding Dynamics in Very Preterm Infants with Delayed Oral Feeding Attainment
Gentle S, Shukla V, Cooley A, Ambalavanan N, Carlo W, Taylor S, Salas A. Feeding Dynamics in Very Preterm Infants with Delayed Oral Feeding Attainment. Neonatology 2025, 1-9. PMID: 40090316, DOI: 10.1159/000543833.Peer-Reviewed Original ResearchPreterm infantsOral feedingProspective observational study of infantsWeeks of oral feedingsObservational study of infantsVery preterm infantsProspective observational studyStudy of infantsDays of initiationFeeding interventionsWeeks gestationInfantsFeeding discontinuitiesRisk of delayWeeksIndividualized carePretermDaysGestationInterventionLPOEstimated Effectiveness of Nirsevimab Against Respiratory Syncytial Virus
Xu H, Aparicio C, Wats A, Araujo B, Pitzer V, Warren J, Shapiro E, Niccolai L, Weinberger D, Oliveira C. Estimated Effectiveness of Nirsevimab Against Respiratory Syncytial Virus. JAMA Network Open 2025, 8: e250380. PMID: 40063022, PMCID: PMC11894488, DOI: 10.1001/jamanetworkopen.2025.0380.Peer-Reviewed Original ResearchConceptsRSV-positive casesCase-control studyRSV infectionLRTI-associated hospitalizationsWeeks postimmunizationLong-acting monoclonal antibodiesTest-negative case-control studyClinical settingRespiratory syncytial virusMultivariate logistic regressionYale New Haven Health SystemRSV diseaseEmergency department dataState immunization registryRSV seasonSyncytial virusNirsevimabPolymerase chain reactionClinical trialsLRTIInfantsPotential confoundersMonoclonal antibodiesBroader outcomesDisease severityInfant sleep state coded from respiration and its relationship to the developing functional connectome: A feasibility study
Mueller I, Rodriguez R, Pini N, Holland C, Ababio R, Inala S, Delapenha K, Mahmoodi V, Khaitova M, Hao X, Fifer W, Scheinost D, Spann M. Infant sleep state coded from respiration and its relationship to the developing functional connectome: A feasibility study. Developmental Cognitive Neuroscience 2025, 72: 101525. PMID: 39965287, PMCID: PMC11876745, DOI: 10.1016/j.dcn.2025.101525.Peer-Reviewed Original ResearchRisk Factors Associated With Food Selectivity in Infants and Toddlers.
Goffredo M, Santoro N, Goffredo P. Risk Factors Associated With Food Selectivity in Infants and Toddlers. Clinical Pediatrics 2025, 99228251315865. PMID: 39895589, DOI: 10.1177/00099228251315865.Peer-Reviewed Original Research636 Is permissive hypercapnia associated with the development of bronchopulmonary dysplasia-associated pulmonary hypertension in preterm infants?
Bhatia K, Nayak A, Jeffcoat S, Carlo W, Ambalavanan N, Gentle S. 636 Is permissive hypercapnia associated with the development of bronchopulmonary dysplasia-associated pulmonary hypertension in preterm infants? The American Journal Of The Medical Sciences 2025, 369: s421-s422. DOI: 10.1016/s0002-9629(25)00642-1.Peer-Reviewed Original Research508 Impacts of red blood cell transfusion and enteral feeding on mesenteric regional tissue oxygenation dynamics in very preterm infants
Salem A, Lukemire J, Ou J, Shenvi N, Barbian M, Saakadze N, Hendrickson J, Easley K, Guo Y, Arthur C, Stowell S, Josephson C, Patel R. 508 Impacts of red blood cell transfusion and enteral feeding on mesenteric regional tissue oxygenation dynamics in very preterm infants. The American Journal Of The Medical Sciences 2025, 369: s331-s332. DOI: 10.1016/s0002-9629(25)00514-2.Peer-Reviewed Original Research
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