2025
Prediction Model for Safe Contrast Volume Thresholds to Prevent Postcontrast Acute Kidney Injury after Endovascular Abdominal Aortic Aneurysm Repair
Bader J, Li Y, Lee C, Li J, Said S, Slade M, Huang Y, Kuwayama D, Guzman R, Ochoa Chaar C. Prediction Model for Safe Contrast Volume Thresholds to Prevent Postcontrast Acute Kidney Injury after Endovascular Abdominal Aortic Aneurysm Repair. Journal Of Vascular Surgery 2025 PMID: 40490161, DOI: 10.1016/j.jvs.2025.05.041.Peer-Reviewed Original ResearchElective endovascular abdominal aortic aneurysm repairEndovascular abdominal aortic aneurysm repairRisk of PC-AKIAbdominal aortic aneurysm repairMultivariate logistic regression analysisAortic aneurysm repairPC-AKIAcute kidney injuryLogistic regression analysisPerioperative mortalityAneurysm repairKidney injuryComplication of endovascular abdominal aortic aneurysm repairPatient characteristicsIncidence of preoperative comorbiditiesPost-contrast acute kidney injuryPostcontrast acute kidney injuryAssociated with development of chronic kidney diseaseAssociated with perioperative mortalityDevelopment of chronic kidney diseaseVascular Quality Initiative databasePreoperative patient characteristicsKaplan-Meier analysisProlonged hospital stayRenal artery stentingP-332 Does endometrial thickness impact live birth rate following a frozen embryo transfer or is there a self-fulfilling prophecy: outcomes of 30,676 euploid single embryo transfers
Genovese H, Mayo C, Kalafat E, Ata B, Fatemi H, Garcia-Velasco J, Seli E. P-332 Does endometrial thickness impact live birth rate following a frozen embryo transfer or is there a self-fulfilling prophecy: outcomes of 30,676 euploid single embryo transfers. Human Reproduction 2025, 40: deaf097.640. DOI: 10.1093/humrep/deaf097.640.Peer-Reviewed Original ResearchLive birth rateModified natural cycleEndometrial thicknessReceiver operating characteristic curveBirth rateFET cyclesEmbryo transferInternational multicenter retrospective cohort studyOdds of live birth rateEuploid single embryo transfersPredictor of live birth rateMulticenter retrospective cohort studyEuploid FET cyclesEndometrial preparation protocolsIn vitro fertilization centerMultivariate logistic regression analysisSingle embryo transferFrozen embryo transferImpact of ETRetrospective cohort studyPredicting live birthLogistic regression analysisOperating characteristics curvePercentage of cyclesEuploid blastocystsReduced sociodemographic disparities in surgical outcomes after spine surgery for spinal epidural abscess
Elsamadicy A, Ghanekar S, Serrato P, Mitre L, Kolb L, Lo S, Sciubba D. Reduced sociodemographic disparities in surgical outcomes after spine surgery for spinal epidural abscess. Journal Of Clinical Neuroscience 2025, 137: 111351. PMID: 40446558, DOI: 10.1016/j.jocn.2025.111351.Peer-Reviewed Original ResearchConceptsNon-Hispanic blacksNon-Hispanic whitesAmerican College of SurgeonsLength of stayNational Surgical Quality Improvement ProgramNon-routine dischargeRacial disparitiesSpinal epidural abscessSpine surgeryReduce racial disparitiesHispanic (HISHighest proportion of individualsQuality Improvement ProgramSurgical Quality Improvement ProgramHealth disparitiesMultivariate logistic regression analysisEpidural abscessSociodemographic disparitiesHealth outcomesLogistic regression analysisProportion of individualsRetrospective cohort studyAdverse eventsCollege of SurgeonsSpinal epidural abscess patientsNon-fatal Overdose and Associated Factors Among People Who Use Opioids: Findings From a Cross-sectional Study
Sujan M, Wickersham J, Khati A, Paudel K, Gautam K, Liautaud D, Crim H, Thapa A, Copenhaver M, Shrestha R. Non-fatal Overdose and Associated Factors Among People Who Use Opioids: Findings From a Cross-sectional Study. Journal Of Community Health 2025, 1-10. PMID: 40381076, DOI: 10.1007/s10900-025-01480-8.Peer-Reviewed Original ResearchNon-fatal overdoseOpioid dependenceCross-sectional studySuicidal ideationHistory of opioid useOpioid overdoseAlcohol use disorderNon-fatal opioid overdoseMental health symptomsAge of participantsParticipants self-reportedHarm reduction interventionsSocio-demographic characteristicsOpioid useEffective prevention strategiesUse disorderDepressive symptomsTargeted harm reduction interventionsHealth symptomsMultivariate logistic regression analysisLogistic regression analysisReduction interventionsOlder participantsCross-sector collaborationRisk of overdoseRetrospective Analysis and Characterization of Avascular Necrosis By Bone Location in Pediatric Leukemia/Lymphoma Patients.
Alayleh A, Naz H, Taylor V, Johnson T, Farook S, Hofmann G, Obilo C, Pham N, Harbacheck K, Laureano T, Smith S, Chao K, Goodman S, Shea K. Retrospective Analysis and Characterization of Avascular Necrosis By Bone Location in Pediatric Leukemia/Lymphoma Patients. Journal Of Pediatric Orthopaedics 2025 PMID: 40214168, DOI: 10.1097/bpo.0000000000002963.Peer-Reviewed Original ResearchAcute lymphoblastic leukemiaAvascular necrosisLeukemia/lymphoma patientsProximal tibial metaphysisSteroid therapyDistal femoral metaphysisHigh-dose steroid therapyMultivariate logistic regression analysisHigh-dose steroidsTibial metaphysisAcute myeloid leukemiaDiagnosis of avascular necrosisFemoral metaphysisEarly detectionBone locationEarly joint replacementLogistic regression analysisImprove functional outcomesAVN diagnosisLong bonesJoint collapseSteroid treatmentEarly-onset osteoarthritisMedian ageMyeloid leukemiaClinical characteristics and outcomes of disseminated intravascular coagulation in patients with severe fever with thrombocytopenia syndrome
Zhang Z, Hu X, Du Q, Mo P, Chen X, Luo M, Jiang Q, Deng L, Xiong Y. Clinical characteristics and outcomes of disseminated intravascular coagulation in patients with severe fever with thrombocytopenia syndrome. BMC Infectious Diseases 2025, 25: 508. PMID: 40217170, PMCID: PMC11992865, DOI: 10.1186/s12879-025-10900-y.Peer-Reviewed Original ResearchConceptsDisseminated intravascular coagulationOutcomes of disseminated intravascular coagulationPresence of disseminated intravascular coagulationNon-DIC groupIndependent risk factorIntravascular coagulationClinical characteristicsRisk factorsDisseminated intravascular coagulation groupThrombocytopenia syndromeMultivariate logistic regression analysisAssociated with high mortalityIn-hospital mortality of patientsCumulative survival rateZhongnan Hospital of Wuhan UniversityMortality of patientsIn-Hospital MortalitySevere feverLogistic regression analysisConsecutive patientsFerritin levelsD-dimerViral loadClinical dataCystatin C296 Associated Risk Factors for Extended Length of Stay following Pediatric Tethered Cord Release: An Analysis of 2012 – 2021 NSQIP-Pediatric Database
Hengartner A, Sayeed S, Serrato P, Belkasim S, Sadeghzadeh S, Kundishora A, DiLuna M, Elsamadicy A. 296 Associated Risk Factors for Extended Length of Stay following Pediatric Tethered Cord Release: An Analysis of 2012 – 2021 NSQIP-Pediatric Database. Neurosurgery 2025, 71: 73-73. DOI: 10.1227/neu.0000000000003360_296.Peer-Reviewed Original ResearchNSQIP-Pediatric databaseTethered cord releaseSpinal cordRisk factorsCord releasePediatric patientsSurgical releaseACS NSQIP-Pediatric databaseFactors associated with prolonged hospitalizationMultivariate logistic regression analysisPostoperative hospital LOSTethered spinal cordCardiac risk factorsRetrospective cohort studyHealthcare resource utilizationAssociated risk factorsMultivariate logistic regressionICD-9/10 codesLogistic regression analysisReoperation ratePerioperative complicationsImprove patient outcomesASA classificationPatient demographicsProlonged hospitalization295 Risk Factors Associated With Postoperative Infection following Pediatric Tethered Cord Release: An Analysis of 2012 – 2021 NSQIP-Pediatric Database
Hengartner A, Serrato P, Sayeed S, Belkasim S, Sadeghzadeh S, DiLuna M, Elsamadicy A. 295 Risk Factors Associated With Postoperative Infection following Pediatric Tethered Cord Release: An Analysis of 2012 – 2021 NSQIP-Pediatric Database. Neurosurgery 2025, 71: 73-73. DOI: 10.1227/neu.0000000000003360_295.Peer-Reviewed Original ResearchSurgical site infectionTethered spinal-cord releaseNSQIP-Pediatric databaseCord releaseAdverse eventsPostoperative infectionFactors associated with surgical site infectionACS NSQIP-Pediatric databaseRisk factors associated with postoperative infectionASA classification 3Multivariate logistic regression analysisTethered cord releaseRetrospective cohort analysisStructural CNS abnormalitiesICD-9/10 codesLogistic regression analysisReduce infection ratesPostoperative complicationsASA scoreCNS abnormalitiesImprove patient outcomesPediatric patientsSite infectionPatient demographicsClinical outcomes126 Intracranial Aneurysm Progression and Rupture States Correlate with Dynamic Aneurysmal Immune Landscape
Antonios J, Gultekin B, Theriault B, Yalcin K, Miyagishima D, Sujijantarat N, Koo A, Haynes J, Nowicki K, Hebert R, Barak T, Matouk C, Gunel M. 126 Intracranial Aneurysm Progression and Rupture States Correlate with Dynamic Aneurysmal Immune Landscape. Neurosurgery 2025, 71: 25-25. DOI: 10.1227/neu.0000000000003360_126.Peer-Reviewed Original ResearchRuptured IAMultivariate logistic regression analysisUnruptured IACD4 T cellsImmune cell subsetsImmune cell populationsAneurysm growth rateImmune cell behaviorLogistic regression analysisImmune cell polarizationNon-invasive strategyImmune signaturesGenes related to immune responseImmune landscapeCell subsetsImmune pathophysiologyImmune profileT cellsImmunological markersAntigen presentationAneurysm progressionImmune cascadePoor morbidityPublic health challengeImmune responseWhat’s in a leader? Association of perceived leadership effectiveness and psychological safety among clinical physician faculty
He C, de Guillebon E, Akhtar S, Pietrzak R, Ripp J, Peccoralo L. What’s in a leader? Association of perceived leadership effectiveness and psychological safety among clinical physician faculty. BMJ Leader 2025, leader-2024-001163. PMID: 40169245, DOI: 10.1136/leader-2024-001163.Peer-Reviewed Original ResearchLeadership effectivenessPsychological safetyPhysician facultyLeadership indexAssociated with psychological safetyPerceived leadership effectivenessCross-sectional surveyClinical faculty membersMultivariate logistic regression analysisOrganisational investmentHealthcare deliveryLogistic regression analysisSeven-itemUrban hospitalsOrganisation questionnaireSafety scorePositive downstream effectsNew York CityMedical CentrePhysiciansOccupational characteristicsAttrition ratesIndex scoreMultivariate modelOccupational correlatesPatterns of Alcohol Use and Daily Smoking Among Men Who Have Sex with Men in Nepal
Paudel K, Gautam K, Hossain Sujan M, Adhikari P, Bhusal S, Wickersham J, Bhakta K, Sapkota S, Dhakal M, Adhikari T, Shrestha R. Patterns of Alcohol Use and Daily Smoking Among Men Who Have Sex with Men in Nepal. Journal Of Community Health 2025, 1-8. PMID: 40042735, DOI: 10.1007/s10900-025-01456-8.Peer-Reviewed Original ResearchPatterns of alcohol useAlcohol useDaily smokingAssociated with alcohol useElevated risk of adverse health outcomesRisk of adverse health outcomesPolice detentionSex workHistory of drug useSmoking cessation programAdverse health outcomesCondomless sexDrug useMultivariate logistic regression analysisHealth outcomesBagmati ProvinceLogistic regression analysisNepalCessation programsMSMElevated riskSmokingMenIndependent correlatesRegression analysisThe Impact of Body Mass Index on Breast Reduction Outcomes: A Multi-Institutional Data Analysis of 45,000 Cases over 15 Years
Knoedler S, Matar D, Kosyk M, Perozzo F, Sofo G, Manente M, Vafa A, Boroumand S, Alfertshofer M, Orgill D, Kim B, Panayi A. The Impact of Body Mass Index on Breast Reduction Outcomes: A Multi-Institutional Data Analysis of 45,000 Cases over 15 Years. Aesthetic Plastic Surgery 2025, 1-15. PMID: 40000470, DOI: 10.1007/s00266-025-04743-w.Peer-Reviewed Original ResearchBody mass indexNational Surgical Quality Improvement ProgramAmerican College of SurgeonsSurgical complicationsMedical complicationsBreast reductionHealthy weightObese IMass indexImpact of body mass indexBody mass index subgroupsLevel of Evidence IIIThis journalSurgical Quality Improvement ProgramElevated body mass indexMultivariate logistic regression analysisCases of surgical complicationsEvidence-Based Medicine ratingsHealthy BMI rangeBreast reduction surgeryHigher BMI classesMulti-institutional databaseEvidence IIIThis journalFemale adult patientsLevel of evidenceQuality Improvement ProgramUnderrepresentation and exclusion of patients with cardiovascular disease in intensive care randomized controlled trials
Ali T, Grimshaw A, Thomas A, Solomon M, Ross J, Miller P. Underrepresentation and exclusion of patients with cardiovascular disease in intensive care randomized controlled trials. European Heart Journal Acute Cardiovascular Care 2025, 14: 259-267. PMID: 39950988, PMCID: PMC12082296, DOI: 10.1093/ehjacc/zuaf023.Peer-Reviewed Original ResearchContemporary cardiac intensive care unitsRandomized Controlled TrialsIschemic heart diseaseCardiovascular diseaseHeart failureDisciplines of critical care medicineHistory of heart failureProspective randomized controlled trialsHeart diseaseControlled TrialsExclusion criteriaMultivariate logistic regression analysisCardiac intensive care unitProportion of patientsExclusion of patientsComorbid cardiovascular diseaseCardiovascular disease historyIntensive care unitLogistic regression analysisApplication of randomized controlled trialsComplex patient populationGeneral internal medicineCardiovascular disease comorbiditiesMulticenter trialIndependent predictorsUnclean cooking fuel use and sleep problems among adults aged 65 years and older from six countries
Smith L, Sánchez G, Rahmati M, Soysal P, Tully M, Barnett Y, Butler L, Yon D, Kim S, Keyes H, Veronese N, Oh H, Kostev K, Jacob L, Shin J, Koyanagi A. Unclean cooking fuel use and sleep problems among adults aged 65 years and older from six countries. American Journal Of Epidemiology 2025, kwaf022. PMID: 39916337, DOI: 10.1093/aje/kwaf022.Peer-Reviewed Original ResearchCooking fuel useNocturnal sleep problemsUnited Nations Sustainable Development Goal 7Unclean cooking fuelsMultivariate logistic regression analysisNationally Representative SampleSleep problemsAdult HealthSleep durationSustainable Development Goal 7Middle-income countriesGlobal ageLogistic regression analysisModern energyCooking fuelWHO StudyCommunity-based dataGoal 7Poor sleep qualityLong sleep durationRepresentative sampleIncidence and predictors of nonresponse to intranasal midazolam in children undergoing laceration repair
Martin S, Bauer K, Heyming T, Zhu J, Lee H, Kain Z. Incidence and predictors of nonresponse to intranasal midazolam in children undergoing laceration repair. Academic Emergency Medicine 2025 PMID: 39901057, DOI: 10.1111/acem.15106.Peer-Reviewed Original ResearchSociable temperamentClinical practice implicationsIntranasal midazolam administrationAnxiety ScaleModified Yale Preoperative Anxiety ScaleTemperamentAnxietyLaceration repairIntranasal midazolamProcedural anxietyEmergency departmentChild ageExtremity lacerationsYoung childrenMultivariate logistic regression analysisChildrenAssociated with likelihoodLogistic regression analysisLong delayYale Preoperative Anxiety ScaleNonrespondersLaceration locationCross-sectional studyProportion of childrenNonresponseThe sex differences in diseases progression and prognosis among persons with HIV and HBV coinfection
Yang R, Chen Q, Jiao F, Yu X, Xiong Y. The sex differences in diseases progression and prognosis among persons with HIV and HBV coinfection. Scientific Reports 2025, 15: 4018. PMID: 39893294, PMCID: PMC11787304, DOI: 10.1038/s41598-025-88530-2.Peer-Reviewed Original ResearchConceptsCD4+ T-lymphocyte countT lymphocyte countsEnd-stage-liver diseaseFIB-4 scoreHBV coinfectionFIB-4HBV DNADecline of HBV DNA levelsDisease progressionLong-term surveillance periodRisk factorsPrevalence of liver cirrhosisHBV co-infectionMultivariate logistic regression analysisHBV DNA levelsProgression of liver diseaseIndependent risk factorLiver disease progressionLiver fibrosis levelsAll-Cause MortalityMultivariate logistic regressionLogistic regression analysisMale groupSex differencesFemale groupP-912. A 10-Year Retrospective, Single-Center Analysis of Nocardiosis in Immunocompetent and Immunocompromised Hosts: Clinical and Microbiological Features, Treatment Outcomes, and Determinants of Central Nervous System Involvement
Roman F, Grubman A, Azar M, Farhadian S. P-912. A 10-Year Retrospective, Single-Center Analysis of Nocardiosis in Immunocompetent and Immunocompromised Hosts: Clinical and Microbiological Features, Treatment Outcomes, and Determinants of Central Nervous System Involvement. Open Forum Infectious Diseases 2025, 12: ofae631.1103. PMCID: PMC11778850, DOI: 10.1093/ofid/ofae631.1103.Peer-Reviewed Original ResearchCentral nervous system involvementCentral nervous systemCNS involvementHost immune statusImmune statusImmunocompromised hostsUnivariate analysisAssociated with CNS involvementCentral nervous system nocardiosisRecipients of solid organ transplantsRisk of CNS involvementNet state of immunosuppressionAssociated with central nervous systemIdentification of Nocardia sppMultivariate logistic regression analysisSingle-center analysisStem cell transplantationState of immunosuppressionAssociated with increased riskCNS diseaseIndependent risk factorSolid organ transplantationNervous system involvementIsolates of NocardiaLogistic regression analysisDevelopment of a Clinical and Ultrasonic Parameter-Based Nomogram Model to Predict Restenosis after Superficial Femoral Artery Stenting
Wang Y, Gao M, Zhao X, Han P, Zhang L, Dardik A. Development of a Clinical and Ultrasonic Parameter-Based Nomogram Model to Predict Restenosis after Superficial Femoral Artery Stenting. Annals Of Vascular Surgery 2025, 113: 175-185. PMID: 39855385, DOI: 10.1016/j.avsg.2024.12.068.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAlloysDecision Support TechniquesEndovascular ProceduresFemaleFemoral ArteryHumansMaleMiddle AgedNomogramsPeripheral Arterial DiseasePredictive Value of TestsRecurrenceReproducibility of ResultsRetrospective StudiesRisk AssessmentRisk FactorsSelf Expandable Metallic StentsStentsTime FactorsTreatment OutcomeConceptsIn-stent restenosisSuperficial femoral arteryDecision curve analysisSuperficial femoral artery stentingLogistic regression analysisPeripheral arterial diseaseReceiver Operating CharacteristicNomogram modelClinical utilityCurve analysisMultivariate logistic regression analysisSelf-expanding bare nitinol stentsTreated with stentingReceiver operating characteristic curveRisk of in-stent restenosisNomogram's clinical utilityBare nitinol stentsPrediction of in-stent restenosisExcellent discriminatory powerRegression analysisFemoral artery stentingArtery flow rateRetrospective studyTraining cohortSFA stenting
2024
Pancreaticoduodenectomy in trauma patients with grade IV–V duodenal or pancreatic injuries: a post hoc analysis of an EAST multicenter trial
Choron R, Piplani C, Kuzinar J, Teichman A, Bargoud C, Sciarretta J, Smith R, Hanos D, Afif I, Beard J, Dhillon N, Zhang A, Ghneim M, Devasahayam R, Gunter O, Smith A, Sun B, Cao C, Reynolds J, Hilt L, Holena D, Chang G, Jonikas M, Echeverria-Rosario K, Fung N, Anderson A, Fitzgerald C, Dumas R, Levin J, Trankiem C, Yoon J, Blank J, Hazelton J, McLaughlin C, Al-Aref R, Kirsch J, Howard D, Scantling D, Dellonte K, Vella M, Hopkins B, Shell C, Udekwu P, Wong E, Joseph B, Lieberman H, Ramsey W, Stewart C, Alvarez C, Berne J, Nahmias J, Puente I, Patton J, Rakitin I, Perea L, Pulido O, Ahmed H, Keating J, Kodadek L, Wade J, Henry R, Schreiber M, Benjamin A, Khan A, Mann L, Mentzer C, Mousafeiris V, Mulita F, Reid-Gruner S, Sais E, Foote C, Palacio C, Argandykov D, Kaafarani H, Manderski M, Moko L, Narayan M, Seamon M. Pancreaticoduodenectomy in trauma patients with grade IV–V duodenal or pancreatic injuries: a post hoc analysis of an EAST multicenter trial. Trauma Surgery & Acute Care Open 2024, 9: e001438. PMID: 39717488, PMCID: PMC11664373, DOI: 10.1136/tsaco-2024-001438.Peer-Reviewed Original ResearchLonger intensive care unit length of stayGrade IV-VBlood product requirementsNon-PD patientsGI complicationsPancreatic injuryPD patientsMulticenter retrospective comparative studyLonger intensive care unit lengthAmerican Association for the SurgeryNon-PDIntensive care unit length of stayGrade VUnit length of stayMultivariate logistic regression analysisIV-VPancreatic ductal injuryProcedure-related morbiditySubanalysis of patientsRetrospective comparative studyLevel 1 trauma centerNon-PD groupLogistic regression analysisYears of agePost Hoc AnalysisSubtyping strokes using blood‐based protein biomarkers: A high‐throughput proteomics and machine learning approach
Misra S, Singh P, Sengupta S, Kushwaha M, Rahman Z, Bhalla D, Talwar P, Nath M, Chakraborty R, Kumar P, Kumar A, Aggarwal P, Srivastava A, Pandit A, Mohania D, Prasad K, Mishra N, Vibha D. Subtyping strokes using blood‐based protein biomarkers: A high‐throughput proteomics and machine learning approach. European Journal Of Clinical Investigation 2024, 55: e14372. PMID: 39655799, DOI: 10.1111/eci.14372.Peer-Reviewed Original ResearchHigh-throughput proteomicsExpressed proteinsSWATH-MSInteraction networkPathway analysisProteomicsProtein biomarkersBlood-based protein biomarkersIntracerebral haemorrhageDifferentiate ISIschemic strokeProteinApo C1Clinical variablesDiscovery phaseMMP-9Multivariate logistic regression analysisLogistic regression analysisCut-off pointCytoscape
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