2025
Nasal Methicillin-Resistant Staphylococcus Aureus Screening in Orthopaedic Patients: We Should Not Ignore Methicillin-Sensitive Staphylococcus Aureus
Abbaszadeh A, Molloy I, Restrepo C, Parvizi J. Nasal Methicillin-Resistant Staphylococcus Aureus Screening in Orthopaedic Patients: We Should Not Ignore Methicillin-Sensitive Staphylococcus Aureus. The Journal Of Arthroplasty 2025 PMID: 40570987, DOI: 10.1016/j.arth.2025.06.072.Peer-Reviewed Original ResearchMethicillin-resistant S. aureusMethicillin-sensitive S. aureusPrevalence of methicillin-resistant S. aureusMethicillin-sensitive S. aureus colonizationPrevalence of methicillin-sensitive S. aureusSurgical site infectionS. aureus colonizationCharlson Comorbidity IndexNasal screeningS. aureusStaphylococcus aureusMethicillin-resistant S. aureus colonizationCause of surgical site infectionMethicillin-resistant Staphylococcus aureus screeningScreening patientsMethicillin-sensitive Staphylococcus aureusOrthopaedic patientsDecolonization of patientsStaphylococcus aureus screeningHistory of coagulopathyOrthopaedic proceduresRisk of colonizationPoorly controlled hypertensionMethicillin-sensitiveElective orthopaedic proceduresReduced 90-Day Cardiovascular and Infectious Complications After Open Reduction Internal Fixation of Ankle Fractures in Type II Diabetic Patients Using Semaglutide Preoperatively.
Seddio A, Vasudevan R, Jonnalagadda A, Slevin J, Grauer J, Fram B. Reduced 90-Day Cardiovascular and Infectious Complications After Open Reduction Internal Fixation of Ankle Fractures in Type II Diabetic Patients Using Semaglutide Preoperatively. Journal Of The American Academy Of Orthopaedic Surgeons 2025 PMID: 40549942, DOI: 10.5435/jaaos-d-25-00439.Peer-Reviewed Original ResearchAnkle fracture ORIFAnkle fracturesInfectious complicationsPostoperative outcomesElixhauser Comorbidity IndexReduction internal fixation of ankle fracturesComorbidity indexInternal fixation of ankle fracturesORIF of ankle fracturesFixation of ankle fracturesDays of follow-upSodium-glucose cotransporter 2 inhibitor useOpen reduction internal fixationHigh-energy injury mechanismsType II diabetic patientsUrinary tract infectionInferior postoperative outcomesSurgical site infectionDeep vein thrombosisType II diabetes mellitusMultivariate logistic regressionII diabetes mellitusElective orthopaedic surgeryTibial plafond fracturesTract infectionsAntibiotic Prophylaxis After Urethroplasty: A Review of the Literature
Cahill E, Patel H, Koch G, Sterling J. Antibiotic Prophylaxis After Urethroplasty: A Review of the Literature. Journal Of Clinical Medicine 2025, 14: 3915. PMID: 40507677, PMCID: PMC12156196, DOI: 10.3390/jcm14113915.Peer-Reviewed Original ResearchUrinary tract infectionAntibiotic prophylaxisTract infectionsImpact of antibiotic prophylaxisEmergence of multidrug-resistant organismsRecurrent urinary tract infectionsSymptomatic urinary tract infectionMultidrug-resistant organismsSurgical site infectionFoley catheter removalEffective surgical treatmentUrethral stricture diseasePostoperative prophylaxisRadical prostatectomyUrethroplasty outcomesCatheter removalOpportunistic infectionsRisk of antibiotics overuseStricture recurrenceHypospadias repairComplication rateSite infectionSurgical treatmentStricture diseaseUrological proceduresAdjuvants to Reduce Perioperative Infection in Orthopaedic Trauma
Mahmoud S, Leslie M, Riedel M. Adjuvants to Reduce Perioperative Infection in Orthopaedic Trauma. 2025, 179-202. DOI: 10.1007/978-3-031-80825-8_16.Peer-Reviewed Original ResearchSurgical site infectionHealthcare-Associated InfectionsComplication associated with increased morbidityRisk of healthcare-associated infectionsOrthopaedic trauma casesOrthopaedic trauma surgeryPerioperative infectionSite infectionPostoperative periodSeverity of injuryTrauma casesTrauma surgeryOrthopaedic traumaInfectionInfection preventionStandard protocolPractice-based reviewWound environmentPrevention effortsPreventive measuresPsychological burdenHost optimization295 Risk Factors Associated With Postoperative Infection following Pediatric Tethered Cord Release: An Analysis of 2012 – 2021 NSQIP-Pediatric Database
Hengartner A, Serrato P, Sayeed S, Belkasim S, Sadeghzadeh S, DiLuna M, Elsamadicy A. 295 Risk Factors Associated With Postoperative Infection following Pediatric Tethered Cord Release: An Analysis of 2012 – 2021 NSQIP-Pediatric Database. Neurosurgery 2025, 71: 73-73. DOI: 10.1227/neu.0000000000003360_295.Peer-Reviewed Original ResearchSurgical site infectionTethered spinal-cord releaseNSQIP-Pediatric databaseCord releaseAdverse eventsPostoperative infectionFactors associated with surgical site infectionACS NSQIP-Pediatric databaseRisk factors associated with postoperative infectionASA classification 3Multivariate logistic regression analysisTethered cord releaseRetrospective cohort analysisStructural CNS abnormalitiesICD-9/10 codesLogistic regression analysisReduce infection ratesPostoperative complicationsASA scoreCNS abnormalitiesImprove patient outcomesPediatric patientsSite infectionPatient demographicsClinical outcomesMicrotia Reconstruction: 30-Day Outcomes for Autograft Versus Implant Reconstruction in a National Surgical Database.
Hu K, Ihnat J, Goss J, Allam O, Parikh N, Salib A, Aral A, Alperovich M. Microtia Reconstruction: 30-Day Outcomes for Autograft Versus Implant Reconstruction in a National Surgical Database. The Cleft Palate-Craniofacial Journal 2025, 10556656251324259. PMID: 40101258, DOI: 10.1177/10556656251324259.Peer-Reviewed Original ResearchImplant reconstructionSurgical site infectionPorous polyethylene implantsHospital lengths-of-staySite infectionWound complicationsAutologous reconstructionEar reconstructionNational Surgical Quality Improvement Project PediatricLengths-of-stayDeep surgical site infectionRate of wound complicationsDays of index surgeryOdds of reoperationHospital readmissionNational surgical databaseImplant-based reconstructionRate of reoperationRetrospective cohort studyOdds of hospital readmissionSynthetic implantsLimited surgeon experienceSurgical databaseSurgeon specialtyComplication rateOutcomes following single level posterior lumbar fusion in patients with systemic and discoid lupus: A retrospective national database study
Dhodapkar M, Halperin S, Day W, Saifi C, Rubio D, Koumpouras F, Grauer J, Varthi A. Outcomes following single level posterior lumbar fusion in patients with systemic and discoid lupus: A retrospective national database study. North American Spine Society Journal (NASSJ) 2025, 22: 100604. PMID: 40487382, PMCID: PMC12141882, DOI: 10.1016/j.xnsj.2025.100604.Peer-Reviewed Original ResearchPosterior lumbar fusionSystemic lupus erythematosusDiscoid lupus erythematosusSingle-level posterior lumbar fusionPostoperative adverse eventsMinor adverse eventsAdverse eventsIncreased oddsLupus erythematosusLumbar fusionDiagnosis of discoid lupus erythematosusCohort of systemic lupus erythematosusLevel posterior lumbar fusionsMultivariate analysisDiagnosis of systemic lupus erythematosusDiscoid lupus erythematosus patientsUrinary tract infectionPerioperative adverse outcomesSurgical site infectionAcute kidney injuryDeep vein thrombosisNational database studyHistory of infectionSampled adult patientsMultivariate logistic regressionAntibiotics and Surgically Treated Acute Appendicitis, When, Where, and Why?
Hendrix A, Kammien A, Maung A, Battacharya B, Davis K, Schuster K. Antibiotics and Surgically Treated Acute Appendicitis, When, Where, and Why? Surgical Infections 2025, 26: 349-354. PMID: 39973176, DOI: 10.1089/sur.2024.264.Peer-Reviewed Original ResearchSurgical site infectionOrgan-space surgical site infectionBody mass indexElixhauser Comorbidity IndexEmergency appendectomyAcute appendicitisBi-variable logistic regression modelPredictive of surgical site infectionClean-contaminated abdominal surgeryIntra-abdominal infectious processIncidence of surgical site infectionOccurrence of surgical site infectionBroad-spectrum antibiotic treatmentOrgan-space infectionsPre-operative antibioticsHour of incisionBroad-spectrum antibioticsPredictive of infectionAdministration timePerforated appendicitisEmergency surgerySite infectionAbdominal surgerySurgical approachAntibiotic treatmentSimultaneous Symmetrizing Surgery on the Contralateral Breast in Unilateral Autologous Breast Reconstruction Is Cost-Effective
Zhao K, Kammien A, Graetz E, Moore M, Evans B, Schneider E, Ayyala H. Simultaneous Symmetrizing Surgery on the Contralateral Breast in Unilateral Autologous Breast Reconstruction Is Cost-Effective. Journal Of Reconstructive Microsurgery 2025 PMID: 39821138, DOI: 10.1055/a-2517-0803.Peer-Reviewed Original ResearchFree flap reconstructionSymmetrization surgeryFlap reconstructionBreast reconstructionDelayed reconstructionPatient characteristicsSingle-stage breast reconstructionUnilateral autologous breast reconstructionAutologous breast reconstructionSurgical site infectionThirty-day complicationsContralateral breastUnilateral reconstructionImmediate reconstructionSite infectionWound dehiscenceThirty-dayIncreased complicationsNational administrative dataSurgeryRevision surgeryComplicationsPatientsWilcoxon testChi-square
2024
Improving cefazolin administration for surgical prophylaxis in reported penicillin allergy: A retrospective study of a health system intervention
Belmont A, Son M, Hyman J, You L, Su C, Kashyap N, Topal J, McManus D, Martinello R, Kwah J. Improving cefazolin administration for surgical prophylaxis in reported penicillin allergy: A retrospective study of a health system intervention. Journal Of Allergy And Clinical Immunology Global 2024, 4: 100377. PMID: 39830990, PMCID: PMC11742594, DOI: 10.1016/j.jacig.2024.100377.Peer-Reviewed Original ResearchPenicillin allergy labelHospital-wide guidelinesSurgical site infectionAllergy labelsSurgical patientsSevere allergic reactionsSurgical prophylaxisSite infectionAssociated with increased rates of surgical site infectionRate of surgical site infectionMulti-drug resistant infectionsAllergic reactionsPrevent surgical site infectionsFirst-line antibioticsFirst-line prophylaxisAdministration of cefazolinAssociated with increased ratesRetrospective cohort studyGuideline-directed therapyAdult surgical patientsPre-intervention groupPost-intervention groupPenicillin allergyPerioperative outcomesCefazolin administrationComplications following open treatment of frontal sinus fracture: A nationwide analysis of 1492 patients
Kammien A, Noel O, Aregbe A, Clune J. Complications following open treatment of frontal sinus fracture: A nationwide analysis of 1492 patients. Journal Of Cranio-Maxillofacial Surgery 2024, 53: 129-133. PMID: 39592374, DOI: 10.1016/j.jcms.2024.11.012.Peer-Reviewed Original ResearchConceptsTreatment of frontal sinus fracturesFrontal sinus fracturesCerebrospinal fluid leakSinus fracturesFrontal sinus obliterationSurgical site infectionOpen treatmentSinus obliterationBrain abscessComplication rateSite infectionFluid leakConcomitant fracturesDays of follow-upSingle-institution studyDay of surgeryType of fractureAssociated with increased likelihoodPosterior tableAdult patientsConcomitant injuriesIncreased injury severityNationwide cohortFollow-upMultivariate analysisImproved total shoulder arthroplasty outcomes associated with semaglutide utilization in patients with type II diabetes: a promising new addition to preoperative optimization
Seddio A, Wilhelm C, Gouzoulis M, Islam W, Vasudevan R, Halperin S, Rubin L, Medvecky M, Donohue K, Grauer J. Improved total shoulder arthroplasty outcomes associated with semaglutide utilization in patients with type II diabetes: a promising new addition to preoperative optimization. JSES International 2024, 9: 735-740. PMID: 40486798, PMCID: PMC12144951, DOI: 10.1016/j.jseint.2024.10.006.Peer-Reviewed Original ResearchTotal shoulder arthroplastyBody mass indexT2DM patientsElixhauser Comorbidity IndexMultivariate analysisOdds of surgical site infectionUrinary tract infectionSurgical site infectionAcute kidney injuryType II diabetes mellitusII diabetes mellitusTract infectionsSite infectionClinical benefitPreoperative optimizationCardiac eventsKidney injuryVenous thromboembolismMetformin useAdverse eventsManagement of type II diabetes mellitusMass indexDiabetes mellitusType II diabetesAdverse outcomesDiagnosis and clinical management of drug allergies in obstetrics and gynecology: an expert review
Burn M, Kwah J, Son M. Diagnosis and clinical management of drug allergies in obstetrics and gynecology: an expert review. American Journal Of Obstetrics And Gynecology 2024, 232: 243-261. PMID: 39490659, DOI: 10.1016/j.ajog.2024.10.025.Peer-Reviewed Original ResearchPenicillin allergyAntibiotic allergyAllergy evaluationDrug allergySkin testOral challengePregnant patientsObstetrician-GynecologistsAntibiotic useAssociated with increased cesarean deliveryAllergy testingGroup B streptococcus sepsisPatient historyNeonatal length of stayManagement of drug allergyIncreased length of hospital stayUnverified penicillin allergyLength of hospital stayFirst-line therapyFirst line antibioticsInduction of drug toleranceHigh-risk patientsSurgical site infectionIncreased surgical site infectionAdministration of antibioticsComparative analysis of negative pressure wound therapy (PICO) and standard dressing application after arterial vascular reconstructions.
Kostiuk V, Fereydooni S, Setia O, Loh S, Strosberg D, Tonnessen B, Ochoa Chaar C, Aboian E. Comparative analysis of negative pressure wound therapy (PICO) and standard dressing application after arterial vascular reconstructions. Vascular 2024, 17085381241296606. PMID: 39460535, DOI: 10.1177/17085381241296606.Peer-Reviewed Original ResearchGroin wound complicationsWound complicationsNegative pressure wound therapyNegative pressure therapyVascular reconstructionGroin dissectionPressure therapyPICO dressingIncidence of groin wound complicationsProcedure indicationArterial reconstructionWound therapyIncidence of wound complicationsReduction of wound complicationsMultivariate logistic regression analysisAssociated with lower riskSurgical site infectionAntibiotics post-operativelyFemoral artery dissectionOpen vascular reconstructionLogistic regression analysisSzilagyi classificationGroin surgerySite infectionPatient demographicsVentral hernia repair with permanent mesh for non-Hispanic black versus white patients: access and post-operative outcomes in the era of robotic surgery
Chao G, Ying L, Huang L, Ma J, Ghiassi S, Gibbs K, Nadzam G, Morton J, Duffy A, Zhou R. Ventral hernia repair with permanent mesh for non-Hispanic black versus white patients: access and post-operative outcomes in the era of robotic surgery. Surgical Endoscopy 2024, 39: 560-567. PMID: 39433584, DOI: 10.1007/s00464-024-11252-5.Peer-Reviewed Original ResearchRobotic surgeryVentral hernia repairBlack patientsHernia repairPermanent meshT-scoreEra of robotic surgeryAbdominal Core Health Quality CollaborativeRate of laparoscopyHigher pain scoresPatient outcomesPost-operative outcomesSurgical site infectionPropensity-score matchingVentral hernia surgeryRecurrence scoreChi-square testPain scoresSite infectionFisher's exactHernia recurrenceOpen approachHernia surgeryWhite patientsSurgeryFrom Novel Facial Measurements to Facial Implantology: A Systematic Review
Baecher H, Scheiflinger A, Remy K, Straub N, Maheta B, Sherwani K, Deniz C, Knoedler S, Safi A, Kauke-Navarro M, Heiland M, Knoedler L. From Novel Facial Measurements to Facial Implantology: A Systematic Review. JPRAS Open 2024, 43: 1-17. PMID: 39639862, PMCID: PMC11616477, DOI: 10.1016/j.jpra.2024.10.005.Peer-Reviewed Original ResearchFacial implantsFacial measurementsOptimal implant planningSurgical site infectionStandard facial measurementsImplant planningSite infectionAesthetic outcomesBone augmentationPotential complicationsWeb of ScienceNasal regionPatient satisfactionPorous polyethyleneComprehensive searchSystematic reviewComplicationsPatientsImplantationOutcomesCentral databaseFacial analysisReviewImplantologyMandibularPatients with fibromyalgia have increased risk of 90-day postoperative adverse events following arthroscopic rotator cuff repair
Rancu A, Katsnelson B, Sanchez J, Winter A, Vasudevan R, Grauer J. Patients with fibromyalgia have increased risk of 90-day postoperative adverse events following arthroscopic rotator cuff repair. JSES International 2024, 9: 360-365. PMID: 40182261, PMCID: PMC11962560, DOI: 10.1016/j.jseint.2024.09.018.Peer-Reviewed Original ResearchRotator cuff repairPostoperative adverse eventsAdverse eventsArthroscopic rotator cuff repairCurrent Procedural TerminologyElixhauser Comorbidity IndexOccurrence of wound dehiscenceEmergency departmentUrinary tract infectionSymptomatic rotator cuff tearsAssociated with increased riskCuff repairLog-rank testYear of surgerySurgical site infectionSevere adverse eventsKaplan-Meier curvesAcute kidney injuryOccurrence of sepsisDeep vein thrombosisMinor adverse eventsRotator cuff repair patientsIndividual adverse eventsOdds of ED utilizationDiagnosis of fibromyalgiaPrediction models for risk assessment of surgical site infection after spinal surgery: A systematic review
Lauinger A, Blake S, Fullenkamp A, Polites G, Grauer J, Arnold P. Prediction models for risk assessment of surgical site infection after spinal surgery: A systematic review. North American Spine Society Journal (NASSJ) 2024, 19: 100518. PMID: 39253699, PMCID: PMC11382011, DOI: 10.1016/j.xnsj.2024.100518.Peer-Reviewed Original ResearchSurgical site infectionPreoperative risk modelSpinal surgerySite infectionAdverse eventsAssessment of surgical site infectionACS NSQIP surgical risk calculatorPostoperative surgical site infectionNSQIP Surgical Risk CalculatorRate of adverse eventsSpine surgery patientsRisk of adverse eventsStratify patient riskSurgical Risk CalculatorField of spine surgeryClinical prediction toolSpine surgeryRisk modelSurgery patientsSurgeryAddressing factorsPatient riskClinical utilitySystematic reviewUnique susceptibilityClassification and Risk Factors for Surgical Site Infections in Radical Cystectomy: A 16-Year Analysis
Lokeshwar S, Choksi A, Smani S, Ip K, Javier-DesLoges J, Rahman S, Leapman M, Martin T, Hesse D. Classification and Risk Factors for Surgical Site Infections in Radical Cystectomy: A 16-Year Analysis. Surgical Infections 2024, 25: 580-585. PMID: 38959160, PMCID: PMC11807858, DOI: 10.1089/sur.2024.107.Peer-Reviewed Original ResearchSurgical site infectionBody mass indexRadical cystectomyCenters for Disease Control and PreventionIndependent risk factorLength of stayRisk factorsAntibiotic agentsSite infectionCenters for Disease Control and Prevention classificationRisk factors of surgical site infectionFactors associated with surgical site infectionFactors of surgical site infectionPredictive of surgical site infectionDeep incision surgical site infectionSurgical site infection predictorsOdds ratioTreatment of surgical site infectionsDeep surgical site infectionPeri-operative characteristicsPeri-operative morbidityCharlson Comorbidity IndexLogistic regression analysisSuperficial incisionalDisease Control and PreventionFever and infections in surgical intensive care: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document
Nohra E, Appelbaum R, Farrell M, Carver T, Jung H, Kirsch J, Kodadek L, Mandell S, Nassar A, Pathak A, Paul J, Robinson B, Cuschieri J, Stein D. Fever and infections in surgical intensive care: an American Association for the Surgery of Trauma Critical Care Committee clinical consensus document. Trauma Surgery & Acute Care Open 2024, 9: e001303. PMID: 38835635, PMCID: PMC11149120, DOI: 10.1136/tsaco-2023-001303.Peer-Reviewed Original ResearchAmerican Association for the SurgeryIntensive care unitClinical consensus documentCatheter-associated urinary infectionDuration of antibiotic treatmentCatheter-related bloodstream infectionNecrotizing soft tissue infectionConsensus documentWorkup of feverIntra-abdominal infectionsSurgical intensive care unitSoft tissue infectionsEvaluation of feverSurgical site infectionVentilator-associated pneumoniaDiagnosis of infectionSurgical intensive careEmpirical antibioticsBloodstream infectionsRespiratory specimensUrinary infectionTissue infectionsSite infectionAntibiotic treatmentTreat infections
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