2025
P-912. A 10-Year Retrospective, Single-Center Analysis of Nocardiosis in Immunocompetent and Immunocompromised Hosts: Clinical and Microbiological Features, Treatment Outcomes, and Determinants of Central Nervous System Involvement
Roman F, Grubman A, Azar M, Farhadian S. P-912. A 10-Year Retrospective, Single-Center Analysis of Nocardiosis in Immunocompetent and Immunocompromised Hosts: Clinical and Microbiological Features, Treatment Outcomes, and Determinants of Central Nervous System Involvement. Open Forum Infectious Diseases 2025, 12: ofae631.1103. PMCID: PMC11778850, DOI: 10.1093/ofid/ofae631.1103.Peer-Reviewed Original ResearchCentral nervous system involvementCentral nervous systemCNS involvementHost immune statusImmune statusImmunocompromised hostsUnivariate analysisAssociated with CNS involvementCentral nervous system nocardiosisRecipients of solid organ transplantsRisk of CNS involvementNet state of immunosuppressionAssociated with central nervous systemIdentification of Nocardia sppMultivariate logistic regression analysisSingle-center analysisStem cell transplantationState of immunosuppressionAssociated with increased riskCNS diseaseIndependent risk factorSolid organ transplantationNervous system involvementIsolates of NocardiaLogistic regression analysis
2016
Immunologic Status Evaluated By the Absolute Lymphocyte/Monocyte Ratio Provides a Powerful Prognostic Tool for Newly Diagnosed Multiple Myeloma
Malek E, Dosani T, Pinto R, Covut F, Akabane H, Driscoll J, De Lima M. Immunologic Status Evaluated By the Absolute Lymphocyte/Monocyte Ratio Provides a Powerful Prognostic Tool for Newly Diagnosed Multiple Myeloma. Blood 2016, 128: 1862. DOI: 10.1182/blood.v128.22.1862.1862.Peer-Reviewed Original ResearchALC/AMC ratioLow ALC/AMC ratioProgression-free survivalAbsolute lymphocyte countAbsolute monocyte countTumor-associated macrophagesHigh absolute monocyte countLow absolute lymphocyte countHost immune statusOverall survivalPrognostic factorsMM patientsHost immune systemPrognostic significanceMultivariate analysisImmune statusSurrogate markerSuperior median progression-free survivalImmune systemPredictors of PFSLymphocyte/monocyte ratioMedian progression-free survivalLonger progression-free survivalDifferent progression-free survivalImmunosuppressive tumor-associated macrophages
2013
Periprosthetic Joint Infection in Patients with Inflammatory Joint Disease: A Review of Risk Factors and Current Approaches to Diagnosis and Management
Morrison T, Figgie M, Miller A, Goodman S. Periprosthetic Joint Infection in Patients with Inflammatory Joint Disease: A Review of Risk Factors and Current Approaches to Diagnosis and Management. HSS Journal ® 2013, 9: 183-194. PMID: 24426866, PMCID: PMC3757491, DOI: 10.1007/s11420-013-9338-8.Peer-Reviewed Original ResearchPeriprosthetic joint infectionManagement of periprosthetic joint infectionInflammatory joint diseaseAnti-tumor necrosis factor medicationsJoint infectionSensitivity to antibiotic therapyRisk of surgical site infectionSerum erythrocyte sedimentation rateDiagnosis of periprosthetic joint infectionTreating periprosthetic joint infectionTreatment of periprosthetic joint infectionDiagnosing PJIErythrocyte sedimentation rateHost immune statusSurgical site infectionDisease-modifying anti-rheumatoid drugsDisease-related inflammationC-reactive proteinTwo-stage revisionReview of risk factorsDuration of infectionAnti-rheumatoid drugsReduced immunosuppressionAntibiotic therapyComprehensive workup
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