2025
Prediction Model for Safe Contrast Volume Thresholds to Prevent Postcontrast Acute Kidney Injury after Endovascular Abdominal Aortic Aneurysm Repair
Bader J, Li Y, Lee C, Li J, Said S, Slade M, Huang Y, Kuwayama D, Guzman R, Ochoa Chaar C. Prediction Model for Safe Contrast Volume Thresholds to Prevent Postcontrast Acute Kidney Injury after Endovascular Abdominal Aortic Aneurysm Repair. Journal Of Vascular Surgery 2025 PMID: 40490161, DOI: 10.1016/j.jvs.2025.05.041.Peer-Reviewed Original ResearchElective endovascular abdominal aortic aneurysm repairEndovascular abdominal aortic aneurysm repairRisk of PC-AKIAbdominal aortic aneurysm repairMultivariate logistic regression analysisAortic aneurysm repairPC-AKIAcute kidney injuryLogistic regression analysisPerioperative mortalityAneurysm repairKidney injuryComplication of endovascular abdominal aortic aneurysm repairPatient characteristicsIncidence of preoperative comorbiditiesPost-contrast acute kidney injuryPostcontrast acute kidney injuryAssociated with development of chronic kidney diseaseAssociated with perioperative mortalityDevelopment of chronic kidney diseaseVascular Quality Initiative databasePreoperative patient characteristicsKaplan-Meier analysisProlonged hospital stayRenal artery stentingA Rare Case of Cyberlindnera jadinii Fungemia in a Kidney Transplant Recipient: A Case Report
Patil J, Sogawa H, Mulligan D. A Rare Case of Cyberlindnera jadinii Fungemia in a Kidney Transplant Recipient: A Case Report. Case Reports In Transplantation 2025, 2025 DOI: 10.1155/crit/3478928.Peer-Reviewed Original ResearchKidney transplant recipientsTransplant recipientsRare caseSolid organ transplant recipientsAspergillus speciesOrgan transplant recipientsAntifungal prophylaxisFungal infectionsCausative agentGraft rejectionPerioperative mortalityCase reportKidney transplantationCardiovascular eventsFungemiaEarly diagnosisQuality of lifeSpeciesKidneyImmunosuppressive pathologyMortalityRecipientsInfectionCandidaAspergillus
2024
Perioperative complications of minor and major reinterventions for peripheral arterial disease
Huttler J, Satam K, Kim T, Zhuo H, Zhang Y, Aboian E, Guzman R, Chaar C. Perioperative complications of minor and major reinterventions for peripheral arterial disease. Vascular 2024, 33: 446-455. PMID: 38597200, DOI: 10.1177/17085381241246907.Peer-Reviewed Original ResearchCatheter-directed thrombolysisLower-extremity revascularizationPeripheral arterial diseaseSurgical reinterventionPerioperative morbidityPerioperative outcomesAssociated with greater perioperative morbiditySubgroup analysisArtery diseaseReturn to the ORRetrospective review of electronic medical recordsPost-operative bleedingReview of electronic medical recordsIncreased perioperative morbidityAcute renal failureVascular Surgery guidelinesTertiary care centerSurgery guidelinesOpen surgeryPerioperative mortalityPerioperative complicationsRetrospective reviewWound infectionRenal failureReinterventionAnticoagulation in Patients with Premature Peripheral Artery Disease Undergoing Lower Extremity Revascularization
Kim T, DeWan A, Murray M, Wang H, Mani A, Mena-Hurtado C, Guzman R, Ochoa Chaar C. Anticoagulation in Patients with Premature Peripheral Artery Disease Undergoing Lower Extremity Revascularization. Annals Of Vascular Surgery 2024, 105: 150-157. PMID: 38593922, DOI: 10.1016/j.avsg.2024.02.006.Peer-Reviewed Original ResearchPremature peripheral arterial diseaseAntiplatelet therapyVascular Quality InitiativeArtery diseaseAdjunct to antiplatelet therapyReturn to the operating roomPost-operative anticoagulationCompared to patientsPostoperative antiplatelet therapyOne-year outcomesCongestive heart failureLower extremity revascularizationMajor adverse limb eventsCoronary artery diseaseEffects of anticoagulantsAmputation-free survivalEarly onset of diseaseAdverse limb eventsPeripheral vascular interventionsOnset of diseasePeripheral arterial diseaseLower-extremity revascularizationPropensity score matchingPerioperative mortalityBaseline characteristics
2023
Second-Line Therapy Sequencing in Primary Warm Autoimmune Hemolytic Anemia: Splenectomy-Rituximab Versus Rituximab-Splenectomy
Waldron C, Ito S, Wang D, Viswanathan G, Butt A, Goshua G. Second-Line Therapy Sequencing in Primary Warm Autoimmune Hemolytic Anemia: Splenectomy-Rituximab Versus Rituximab-Splenectomy. Blood 2023, 142: 2317. DOI: 10.1182/blood-2023-189957.Peer-Reviewed Original ResearchWarm autoimmune hemolytic anemiaSecond-line therapyAutoimmune hemolytic anemiaAdult patientsHemolytic anemiaSecond-line treatmentFirst-line treatmentPrevention of thrombosisDegree of anemiaLaparoscopic surgical techniquesPatient's disease statusQuality-adjusted life expectancyRate of infectionProbabilistic sensitivity analysesNet monetary benefitRituximab cyclesTherapy sequencingComplete remissionPartial remissionPerioperative mortalityPrimary outcomeTherapeutic sequencingLaparoscopic techniquePreferred treatmentRelapse riskPerioperative Mortality of the COVID-19 Recovered Patient Compared to a Matched Control: A Multicenter Retrospective Cohort Study
Aziz M, Schenning K, Koike S, O’Glasser A, O’Reilly-Shah V, Sera V, Mathis M, Naik B, Taicher B, Colquhoun D, Freundlich R, Schonberger R, Domino K, Chen L, Pace N. Perioperative Mortality of the COVID-19 Recovered Patient Compared to a Matched Control: A Multicenter Retrospective Cohort Study. Anesthesiology 2023, 140: 195-206. PMID: 37844271, DOI: 10.1097/aln.0000000000004809.Peer-Reviewed Original ResearchConceptsAcute kidney injuryPulmonary complicationsKidney injuryIncreased riskPerioperative mortalityExposed patientsCOVID-19 infectionIncreased 30-day mortality riskElective surgeryIncreased risk of acute kidney injuryIncreased risk of pulmonary complicationsRisk of acute kidney injuryMortality riskPositive testRisk of pulmonary complicationsRisk of perioperative mortalityRetrospective observational cohort studyThirty-day mortalityCOVID-19-recovered patientsCohort of patientsExposure to COVID-19 infectionIncreased risk of mortalityAssociated with increased mortality riskObservational cohort studyElective inpatient surgeryRespect the Middle Lobe: Perioperative Risk of Bilobectomy Compared With Lobectomy and Pneumonectomy
Li A, Canavan M, Ermer T, Maduka R, Zhan P, Pichert M, Boffa D, Blasberg J. Respect the Middle Lobe: Perioperative Risk of Bilobectomy Compared With Lobectomy and Pneumonectomy. The Annals Of Thoracic Surgery 2023, 117: 163-171. PMID: 37774762, DOI: 10.1016/j.athoracsur.2023.09.023.Peer-Reviewed Original ResearchConceptsLower bilobectomyLeft pneumonectomyLung cancerMiddle lobeRight-sided lung cancerCox proportional hazards modelThirty-day morbidityTotal lung functionPreoperative risk stratificationThoracic Surgeons databaseProportional hazards modelPneumonectomy patientsUpper bilobectomyBronchial involvementPerioperative mortalityPerioperative riskPerioperative variablesPatient demographicsPulmonary resectionRight pneumonectomySecondary outcomesLung functionMiddle lobectomyPrimary outcomePropensity matchingThe management of patients with popliteal artery aneurysms presenting with acute limb ischemia
Satam K, Aboian E, Cardella J, Slade M, Nassiri N, Dardik A, Guzman R, Ochoa Chaar C. The management of patients with popliteal artery aneurysms presenting with acute limb ischemia. Journal Of Vascular Surgery 2023, 78: 506-513. PMID: 37086824, DOI: 10.1016/j.jvs.2023.04.019.Peer-Reviewed Original ResearchConceptsAcute limb ischemiaEndovascular repairPeripheral vascular interventionsOpen repairLimb ischemiaEndovascular popliteal artery aneurysm repairPopliteal artery aneurysm repairVascular Quality Initiative databaseMajor amputation ratePopliteal artery aneurysmsCoronary artery diseaseManagement of patientsLong-term outcomesMultivariable regression analysisHigher inpatientMajor amputationPAA repairAmputation rateHospital lengthPerioperative complicationsPerioperative mortalityPostoperative lengthDecreased complicationsInfrainguinal bypassOnly patientsThe association between diabetes mellitus and its management with outcomes following endovascular repair for descending thoracic aortic aneurysm
Summers S, Rastogi V, Yadavalli S, Wang S, Schaller M, Jones D, Ochoa Chaar C, de Bruin J, Verhagen H, Schermerhorn M. The association between diabetes mellitus and its management with outcomes following endovascular repair for descending thoracic aortic aneurysm. Journal Of Vascular Surgery 2023, 78: 313-323. PMID: 36966848, DOI: 10.1016/j.jvs.2023.02.024.Peer-Reviewed Original ResearchConceptsThoracic aortic aneurysmDiabetes mellitusNoninsulin medicationsPerioperative mortalityAortic aneurysmHospital complicationsEndovascular repairDietary managementSimilar perioperative mortalityMultivariable Cox regressionHigh perioperative mortalityVascular Quality InitiativeMultivariable logistic regressionEndovascular aneurysm repairMultivariable regression analysisDM statusNoninsulin therapySac regressionInsulin therapyTherapy cohortAneurysm repairDietary therapyDM subgroupCox regressionInsulin medication
2022
A guide for managing patients with stage I NSCLC: deciding between lobectomy, segmentectomy, wedge, SBRT and ablation—part 3: systematic review of evidence regarding surgery in compromised patients or specific tumors
Bade BC, Blasberg JD, Mase VJ, Kumbasar U, Li AX, Park HS, Decker RH, Madoff DC, Brandt WS, Woodard GA, Detterbeck FC. A guide for managing patients with stage I NSCLC: deciding between lobectomy, segmentectomy, wedge, SBRT and ablation—part 3: systematic review of evidence regarding surgery in compromised patients or specific tumors. Journal Of Thoracic Disease 2022, 0: 0-0. PMID: 35813753, PMCID: PMC9264070, DOI: 10.21037/jtd-21-1825.Peer-Reviewed Original ResearchLimited pulmonary reserveLong-term outcomesResection extentNon-randomized comparisonPulmonary reserveOlder patientsIndividual patientsFavorable tumorsSystematic reviewStage I lung cancerFavorable long-term outcomeI lung cancerScreen-detected tumorsStage I NSCLCCharacteristics of patientsShort-term outcomesLesser resectionsPerioperative mortalityPulmonary functionSublobar resectionWedge resectionPatient selectionRandomized trialsLung cancerResidual confoundingPediatric surgical quality improvement in low- and middle-income countries: What data to collect?
Ullrich S, Kisa P, Muzira A, Kakembo N, Nabukenya M, Tumukunde J, Sekabira J, Chang D, Ozgediz D. Pediatric surgical quality improvement in low- and middle-income countries: What data to collect? Surgery 2022, 171: 1067-1072. PMID: 35078626, DOI: 10.1016/j.surg.2021.09.010.Peer-Reviewed Original ResearchConceptsMiddle-income countriesPerioperative mortalityMedical recordsMulago National Referral HospitalRisk adjustmentPediatric surgery wardNational Referral HospitalOverall mortality ratePatients' medical recordsRisk-adjusted outcomes dataIncome countriesAdequate risk adjustmentSurgical quality improvementReferral hospitalSurgery wardPrimary diagnosisPatient outcomesHigh-income countriesSurgical accessSurgical qualityOutcome dataMortality rateMinimum datasetHospital administratorsPatients
2021
A Comparison of Clinical Outcomes of Endovascular Repair Versus Open Surgery for Ruptured Descending Thoracic Aorta
Xie X, Shu X, Zhang W, Guo D, Zhang W, Wang L, Fu W. A Comparison of Clinical Outcomes of Endovascular Repair Versus Open Surgery for Ruptured Descending Thoracic Aorta. Journal Of Endovascular Therapy 2021, 29: 307-318. PMID: 34779300, DOI: 10.1177/15266028211057087.Peer-Reviewed Original ResearchConceptsRe-intervention rateDescending Thoracic AortaOpen surgeryThoracic aortaRe-interventionPulmonary complicationsCardiac complicationsPerioperative mortalityPulmonary embolismAssociated with lower perioperative mortalityOdds ratioThoracic endovascular aortic repairYear mortalityEarly postoperative complicationsEndovascular aortic repairLow perioperative mortalityMeta-analysisRuptured thoracic aortaCochrane Library databasesAssociated with lower ratesConfidence intervalsTEVAR groupOS outcomesAortic repairPerioperative morbidityImproving Surgical Research Capacity in Low and Middle Income Countries: Can Pulse Data Collection Reliably Estimate Perioperative Mortality?
Ullrich S, Kisa P, Muzira A, White E, Nabukenya M, Tumukunde J, Kakembo N, Sekabira J, Chang D, Ozgediz D. Improving Surgical Research Capacity in Low and Middle Income Countries: Can Pulse Data Collection Reliably Estimate Perioperative Mortality? Journal Of The American College Of Surgeons 2021, 233: s108-s109. DOI: 10.1016/j.jamcollsurg.2021.07.207.Peer-Reviewed Original ResearchEffect of Ischemic Cardiomyopathy on Perioperative Mortality After Endovascular Abdominal Aortic Aneurysm Repair
Bellamkonda K, Zogg C, Nassiri N, Strosberg D, Desai N, Guzman R, Chaar C. Effect of Ischemic Cardiomyopathy on Perioperative Mortality After Endovascular Abdominal Aortic Aneurysm Repair. Journal Of Vascular Surgery 2021, 74: e131-e132. DOI: 10.1016/j.jvs.2021.06.202.Peer-Reviewed Original ResearchImproving Surgical Research Capacity in Low- and Middle-Income Countries
Ullrich SJ, Kisa P, Muzira A, White EM, Nabukenya M, Tumukunde J, Kakembo N, Sekabira J, Chang DC, Ozgediz D. Improving Surgical Research Capacity in Low- and Middle-Income Countries. Annals Of Surgery 2021, 277: e714-e718. PMID: 34334654, DOI: 10.1097/sla.0000000000005105.Peer-Reviewed Original ResearchConceptsPerioperative mortalityMiddle-income countriesMulago National Referral HospitalNational Referral HospitalResource-constrained settingsReferral hospitalEligible casesSampling frameHigh-income countriesSurgical careSurgical casesSurgical systemSample percentageSample sizeImprovement goalsResearch capacityData collection
2020
Survival After Cancer Treatment at Top-Ranked US Cancer Hospitals vs Affiliates of Top-Ranked Cancer Hospitals
Boffa DJ, Mallin K, Herrin J, Resio B, Salazar MC, Palis B, Facktor M, McCabe R, Nelson H, Shulman LN. Survival After Cancer Treatment at Top-Ranked US Cancer Hospitals vs Affiliates of Top-Ranked Cancer Hospitals. JAMA Network Open 2020, 3: e203942. PMID: 32453382, PMCID: PMC7251445, DOI: 10.1001/jamanetworkopen.2020.3942.Peer-Reviewed Original ResearchConceptsLong-term survivalCancer HospitalSurgical treatmentShort-term survivalComplex cancer treatmentAffiliate hospitalsCancer treatmentCancer careAdjusted long-term survivalNational Cancer DatabaseAnnual surgical volumeComplex cancer careIndividuals 18 yearsComplex surgical proceduresPerioperative mortalityCohort studyAffiliated HospitalPooled analysisBladder cancerCancer DatabasePatient outcomesSurgical volumeSurgical proceduresMAIN OUTCOMESurvival advantageLong-term follow up outcomes of surgical resection of Shamblin Ⅱ/Ⅲ carotid body tumor: a single center analysis
Zhang W, Liu F, Wang L, Guo D, Xu X, Chen B, Jiang J, Yang J, Shi Z, Fu W. Long-term follow up outcomes of surgical resection of Shamblin Ⅱ/Ⅲ carotid body tumor: a single center analysis. Chinese Journal Of General Surgery 2020, 35: 195-198. DOI: 10.3760/cma.j.cn113855-20191209-00724.Peer-Reviewed Original ResearchCarotid body tumorTumor sizeNeurological complicationsShamblin IISurgical resectionBlood lossProcedure timePatient died of multi-organ failureMalignant carotid body tumorLength of hospital stayVascular interventionsProcedural blood lossMulti-organ failureLong-term prognosisPatient diedTumor resectionBody tumorsPerioperative mortalitySurgical outcomesHospital stayResectionShamblinTumorPatientsComplicationsThe Clinical Implications of Spontaneous Hemorrhage in Vestibular Schwannomas
Hong CS, Jin L, David WB, Shear B, Zhao AY, Zhang Y, Erson-Omay EZ, Fulbright RK, Huttner A, Kveton J, Moliterno J. The Clinical Implications of Spontaneous Hemorrhage in Vestibular Schwannomas. Journal Of Neurological Surgery Part B Skull Base 2020, 82: e22-e32. PMID: 34306914, PMCID: PMC8289498, DOI: 10.1055/s-0040-1701676.Peer-Reviewed Original ResearchExtent of resectionVestibular schwannomaFacial weaknessSpontaneous hemorrhageLarge tumorsManagement of VSRetrospective case review seriesThin-walled vascular channelsBlood-thinning medicationHemorrhagic vestibular schwannomaPreoperative facial weaknessHalf of patientsFacial nerve dysfunctionRelevant clinical factorsPatient health outcomesRapid symptom onsetHigh mortality rateCase review seriesFacial numbnessNerve dysfunctionPerioperative mortalityClinical factorsSymptom onsetBenign pathologyPoor prognosis
2019
Perioperative Outcomes of Lower Extremity Revascularization for Rest Pain and Tissue Loss
Tsay C, Luo J, Zhang Y, Attaran R, Dardik A, Ochoa Chaar CI. Perioperative Outcomes of Lower Extremity Revascularization for Rest Pain and Tissue Loss. Annals Of Vascular Surgery 2019, 66: 493-501. PMID: 31756416, DOI: 10.1016/j.avsg.2019.11.019.Peer-Reviewed Original ResearchMeSH KeywordsAdolescentAdultAgedAged, 80 and overAmputation, SurgicalCritical IllnessDatabases, FactualFemaleGangreneHumansIschemiaLeg UlcerLength of StayLimb SalvageLower ExtremityMaleMiddle AgedPainPatient ReadmissionPeripheral Arterial DiseasePostoperative ComplicationsRetrospective StudiesRisk AssessmentRisk FactorsSeverity of Illness IndexTime FactorsTreatment OutcomeUnited StatesVascular GraftingYoung AdultConceptsCritical limb ischemiaRest painMajor amputationTissue lossPerioperative outcomesTL patientsSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseSevere peripheral artery diseaseQuality Improvement Program databaseTerms of pneumoniaWorse perioperative outcomesLonger hospital stayHigher American SocietyImprovement Program databasePeripheral artery diseaseCongestive heart failureLower extremity revascularizationICD-10 codesAnesthesiologists classUnplanned intubationHospital stayPerioperative mortalityExtremity revascularizationLimb ischemiaAssociation of Preoperative Frailty With Intraoperative Hemodynamic Instability and Postoperative Mortality
James L, Levin M, Lin H, Deiner S. Association of Preoperative Frailty With Intraoperative Hemodynamic Instability and Postoperative Mortality. Anesthesia & Analgesia 2019, Publish Ahead of Print: &na;. PMID: 31094800, DOI: 10.1213/ane.0000000000004085.Peer-Reviewed Original ResearchConceptsMean arterial pressureIntraoperative hemodynamic variablesPerioperative mortalityAbsolute change >Hemodynamic variablesAssociation of preoperative frailtyAmerican Society of Anesthesiologists classSingle-center retrospective studyAssociated with perioperative mortalityBody mass index <Intraoperative blood pressure variationsAssociated with increased mortalityIntraoperative hemodynamic instabilityLength of surgeryIntact autonomic nervous systemAssociated with mortalityAssociated with >Marker of frailtyDecreased physiologic reserveAutonomic nervous systemFrailty conditionsPostoperative mortalityHemodynamic instabilityRelationship of frailtyAutonomic dysfunction
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