2025
Guidelines for Enhanced Recovery After Trauma and Intensive Care (ERATIC): Enhanced Recovery After Surgery (ERAS) and International Association for Trauma Surgery and Intensive Care (IATSIC) Society Recommendations: Paper 2: Postoperative and Intensive Care Recommendations
Hardcastle T, Gaarder C, Balogh Z, D'amours S, Davis K, Gupta A, Mohseni S, Naess P, Naidoo S, Razek T, Robertson S, Uchino H, Zonies D, Whing J, Scott M. Guidelines for Enhanced Recovery After Trauma and Intensive Care (ERATIC): Enhanced Recovery After Surgery (ERAS) and International Association for Trauma Surgery and Intensive Care (IATSIC) Society Recommendations: Paper 2: Postoperative and Intensive Care Recommendations. World Journal Of Surgery 2025, 49: 2029-2054. PMID: 40696568, PMCID: PMC12338449, DOI: 10.1002/wjs.70004.Peer-Reviewed Original ResearchConceptsGrading of RecommendationsTrauma carePostresuscitation phaseModified two-round Delphi methodIntensive careInternational Association for Trauma SurgeryLength of hospital stayComponents of careSystems of carePhase of careTwo-round Delphi methodTrauma surgical patientsMEDLINE database searchRandomized clinical trialsLevel of evidenceElective surgical proceduresLength of stayCare recommendationsEmergency surgeryEnglish-language publicationsOverall careERAS componentsPostoperative treatmentHospital stayConsensus guidelinesAnterior Quadratus Lumborum Block for Microvascular Free-Flap Breast Reconstruction: A Propensity-Score-Weighted Study
Pierson D, Kim L, Lin H, Long A, Zurich H, Evans B, Wu C, He Z, Dai F, Ayyala H, Golshan M, Li J. Anterior Quadratus Lumborum Block for Microvascular Free-Flap Breast Reconstruction: A Propensity-Score-Weighted Study. A&A Practice 2025, 19: e02017. PMID: 40698851, DOI: 10.1213/xaa.0000000000002017.Peer-Reviewed Original ResearchConceptsAnterior quadratus lumborum blockContinuous quality improvementDeep inferior epigastric artery perforatorFree flap breast reconstructionPostoperative opioid consumptionLength of stayMilligram morphine equivalentsOpioid consumptionQuadratus lumborum blockPost-anesthesia care unitDexamethasone sodium phosphateLiposomal bupivacainePain scoresMethylprednisolone acetateBreast reconstructionUltrasound-guided anterior quadratus lumborum blockMicrosurgical free flap breast reconstructionMicrovascular free flap breast reconstructionAverage daily opioid consumptionAverage daily pain scoreSecondary outcomesInferior epigastric artery perforatorDeep inferior epigastric artery perforator flap reconstructionDaily opioid consumptionDaily pain scoresReduced sociodemographic disparities in surgical outcomes after spine surgery for spinal epidural abscess
Elsamadicy A, Ghanekar S, Serrato P, Mitre L, Kolb L, Lo S, Sciubba D. Reduced sociodemographic disparities in surgical outcomes after spine surgery for spinal epidural abscess. Journal Of Clinical Neuroscience 2025, 137: 111351. PMID: 40446558, DOI: 10.1016/j.jocn.2025.111351.Peer-Reviewed Original ResearchConceptsNon-Hispanic blacksNon-Hispanic whitesAmerican College of SurgeonsLength of stayNational Surgical Quality Improvement ProgramNon-routine dischargeRacial disparitiesSpinal epidural abscessSpine surgeryReduce racial disparitiesHispanic (HISHighest proportion of individualsQuality Improvement ProgramSurgical Quality Improvement ProgramHealth disparitiesMultivariate logistic regression analysisEpidural abscessSociodemographic disparitiesHealth outcomesLogistic regression analysisProportion of individualsRetrospective cohort studyAdverse eventsCollege of SurgeonsSpinal epidural abscess patientsImpact of skilled nursing facility discharge on inpatient oncology quality outcomes
Rothberg B, Morris J. Impact of skilled nursing facility discharge on inpatient oncology quality outcomes. JNCI Cancer Spectrum 2025, 9: pkaf055. PMID: 40408163, PMCID: PMC12202314, DOI: 10.1093/jncics/pkaf055.Peer-Reviewed Original ResearchConceptsSkilled nursing facilityNursing facilitiesMedical oncology serviceLength of staySelf-CareSeverity of illness indexReadmission ratesOncology servicesSkilled nursing facility dischargeImprove care qualityHouse staff teamsIllness indexOncology patientsImproved length of stayCare qualityThirty-day readmission ratesDischarge planningTime of dischargeQuality outcomesPractice improvementFacility dischargeStaff teamsRandom interceptReadmissionHospitalist comanagementEfficacy of enhanced recovery programmes for cardiac surgery: a systematic review and meta-analysis
Hoogma D, Meeusen I, Coppens S, Verbrugghe P, van den Eynde J, Engelman D, Grant M, Stoppe C, Rex S. Efficacy of enhanced recovery programmes for cardiac surgery: a systematic review and meta-analysis. British Journal Of Anaesthesia 2025, 135: 31-39. PMID: 40287362, DOI: 10.1016/j.bja.2025.03.019.Peer-Reviewed Original ResearchConceptsHospital length of stayLength of stayCardiac surgeryFast-track cardiac anesthesiaFast-track (FTICU length of stayMeta-analysisAssessed risk of biasRandom-effects modelAdditive valueRisk of biasPerioperative strategiesEfficacy outcomesVentilation timeFT programmesVentilatory timeHospital lengthPostoperative interventionsCardiac anesthesiaComparative efficacySurgeryWeb of ScienceRandomised trialsPRISMA guidelinesEnhanced recoverySame‐Day Discharge After Catheter Ablation of Atrial Fibrillation in the United States
Sandhu A, Qin L, Minges K, Zimmerman S, Borne R, Polsinelli V, Ho P, Hsu J, Al‐Khatib S, Freeman J, Bradley S, Rao S, Hernandez A, Tzou W, Varosy P, Hess P. Same‐Day Discharge After Catheter Ablation of Atrial Fibrillation in the United States. Journal Of The American Heart Association 2025, 14: e039190. PMID: 40240938, PMCID: PMC12184264, DOI: 10.1161/jaha.124.039190.Peer-Reviewed Original ResearchConceptsSame-day dischargeRate of same-day dischargeAF ablationComplication rateAtrial fibrillationPersistent AFCatheter ablation of atrial fibrillationAblation of atrial fibrillationOvernight hospitalizationLikelihood of same-day dischargeSame-day discharge ratePostprocedural complication rateSame-day discharge patientsSubstantial hospital variationCatheter ablationDays postprocedureClinical factorsBlack raceIndex procedureComorbid conditionsPatientsHospital variationSame-dayHospitalComplicationsDoes Stapling Platform Influence Robotic Sleeve Gastrectomy Postoperative Outcomes?
Ying L, Rutledge R, Butensky S, Lugo D, Morton J, Ringold F. Does Stapling Platform Influence Robotic Sleeve Gastrectomy Postoperative Outcomes? Obesity Surgery 2025, 35: 1838-1844. PMID: 40227538, PMCID: PMC12065732, DOI: 10.1007/s11695-025-07855-z.Peer-Reviewed Original ResearchConceptsGastroesophageal reflux diseasePostoperative outcomesNo significant differenceSleeve gastrectomyRate of de novo GERDStapler useOverall side effect profileRetrospective single-surgeon studyLinear staplerPostoperative refluxOperative timePostoperative length of stayBackgroundLaparoscopic sleeve gastrectomyPostoperative gastroesophageal reflux diseaseRate of postoperative refluxSingle-surgeon studySide effect profileSignificant differenceWeight lossWeight loss surgeryRobotic-assisted sleeve gastrectomyLength of stayPostoperative lengthPatient demographicsEffect profileImpact of Social Determinants of Health on Outcomes of Nontraumatic Subarachnoid Hemorrhage
Renedo D, Rivier C, Koo A, Clocchiatti‐Tuozzo S, Huo S, Sujijantarat N, Torres‐Lopez V, Hebert R, Schwamm L, de Havenon A, Gunel M, Matouk C, Falcone G, Sheth K. Impact of Social Determinants of Health on Outcomes of Nontraumatic Subarachnoid Hemorrhage. Journal Of The American Heart Association 2025, 14: e037199. PMID: 40194963, PMCID: PMC12132901, DOI: 10.1161/jaha.124.037199.Peer-Reviewed Original ResearchConceptsSocial determinants of healthSocial deprivation indexDeterminants of healthImpact of social determinants of healthDeprivation indexLength of stayInfluence of social determinants of healthOdds ratioDischarge dispositionHigher social deprivation indexAssociated with reduced oddsAverage length of stayVascular risk factorsAssociated with longer lengthSocial determinantsSignificant health burdenEstimate associationsIn-Hospital DeathNontraumatic subarachnoid hemorrhageSocioeconomic levelHealth burdenOverall mortality rateDecreased deathRisk factorsHealthABO blood group and COVID-19 severity: Associations with endothelial and adipocyte activation in critically ill patients
Stukas S, Goshua G, Conway E, Lee A, Hoiland R, Sekhon M, Chen L. ABO blood group and COVID-19 severity: Associations with endothelial and adipocyte activation in critically ill patients. PLOS ONE 2025, 20: e0320251. PMID: 40173171, PMCID: PMC11964209, DOI: 10.1371/journal.pone.0320251.Peer-Reviewed Original ResearchConceptsABO blood groupCritically ill patientsIntensive care unitAB blood typeBlood groupEndothelial injuryInflammatory cytokinesLength of intensive care unitRetrospective single-center studyMarkers of endothelial activationIll patientsMarkers of endothelial injuryDays of ICU staySerum inflammatory markersSingle-center studySeverity of COVID-19 infectionSerum inflammatory cytokinesBlood typeVancouver General HospitalSevere COVID-19SARS-CoV-2 infectionSeverity of diseaseCOVID-19 severityAdipsin levelsEndothelial activationTrends in Preventable Hospitalization Rates for Children With or Without Observation Stay Data
Tian Y, Macy M, Hockenberry J, Holl J, Sabbatini A, Ackermann R, Kan K, Huang L, Raval M. Trends in Preventable Hospitalization Rates for Children With or Without Observation Stay Data. JAMA Network Open 2025, 8: e251533. PMID: 40126481, PMCID: PMC11933988, DOI: 10.1001/jamanetworkopen.2025.1533.Peer-Reviewed Original ResearchConceptsAmbulatory care sensitive conditionsPediatric ambulatory care sensitive conditionsPreventable hospitalization ratesAnnual percentage changeHospitalization ratesPercentage changeCross-sectional studyRetrospective cross-sectional studyHospital stay dataAmbulatory careInpatient dataMain OutcomesHealthcare costsSensitive conditionsInpatient-onlyObservation staysPediatric hospitalPatients aged 6Aged 6Quality indicatorsPatient statusHospitalDisease surveillanceCounty levelImpact of policiesFinding the optimal length of stay for veterans in substance use disorder residential treatment using generalized propensity score modeling
Dams G, Gross G, Ketchen B, Smith N, Burden J. Finding the optimal length of stay for veterans in substance use disorder residential treatment using generalized propensity score modeling. International Journal Of Drug Policy 2025, 137: 104715. PMID: 40024631, DOI: 10.1016/j.drugpo.2025.104715.Peer-Reviewed Original ResearchConceptsSubstance use disordersResidential treatmentSevere substance use disordersTreatment outcomesComplex clinical needsVeterans AffairsResidential programsLength of stayDepartment of Veterans AffairsOptimal length of stayResidential centersMethodological issuesVeteransEnhanced outcomesClinical assessmentIndividual patient needsGeneralized propensity score model
2024
Effectiveness of primary repair for low anorectal malformations in Uganda
Oyania F, Ullrich S, Hellmann Z, Stephens C, Kotagal M, Commander S, Shui A, Situma M, Odongo C, Kituuka O, Bajunirwe F, Ozgediz D, Poenaru D. Effectiveness of primary repair for low anorectal malformations in Uganda. Pediatric Surgery International 2024, 40: 315. PMID: 39560775, PMCID: PMC12032398, DOI: 10.1007/s00383-024-05905-8.Peer-Reviewed Original ResearchConceptsThree-stage repairTwo-stage repairPrimary repairLength of hospital stayLow anorectal malformationPost-operative complicationsLonger treatment durationLength of treatmentNon-inferiority analysisResource-limited settingsBackgroundAnorectal malformationsNeonatal surgeryProspective armRetrospective armAnorectal malformationsPostoperative complicationsSurgeon experienceColostomy closureHospital stayLive birthsSurgical accessColostomy formationUgandan childrenNon-inferiorityClinical trialsEffects of Buprenorphine, Methadone, and Substance Use on COVID-19 Morbidity and Mortality
Christian N, Zhou X, Radhakrishnan R. Effects of Buprenorphine, Methadone, and Substance Use on COVID-19 Morbidity and Mortality. Journal Of Addiction Medicine 2024, 19: 223-226. PMID: 39475125, DOI: 10.1097/adm.0000000000001386.Peer-Reviewed Original ResearchConceptsActive substance useSubstance useAssociated with increased morbidityDuration of hospitalizationCOVID-19 outcomesOpioid useSubstance use disordersImpact of substance useCOVID-19 infectionEffects of buprenorphineOpioid use disorderRetrospective cohort studyUse disorderAll-Cause MortalityCOVID-19 positive patientsUrine toxicologyMultivariate logistic regressionAssociated with statistically significant increasesMedical comorbidityStatistically significant differenceMOUD treatmentStatistically significant increaseAssociated with worse COVID-19 outcomesCOVID-19 morbidityUrban hospital systemOptimizing hospital length of stay after infrainguinal bypass: Should ultrashort set the bar?
Said S, Ochoa Chaar C. Optimizing hospital length of stay after infrainguinal bypass: Should ultrashort set the bar? Journal Of Vascular Surgery 2024, 80: 1191. PMID: 39306445, DOI: 10.1016/j.jvs.2024.05.006.Peer-Reviewed Original ResearchUse of Early Ketamine Sedation and Association With Clinical and Cost Outcomes Among Mechanically Ventilated Patients With COVID-19: A Retrospective Cohort Study
Royce-Nagel G, Jarzebowski M, Wongsripuemtet P, Krishnamoorthy V, Fuller M, Ohnuma T, Treggiari M, Yaport M, Cobert J, Garrigan E, Bartz R, Raghunathan K. Use of Early Ketamine Sedation and Association With Clinical and Cost Outcomes Among Mechanically Ventilated Patients With COVID-19: A Retrospective Cohort Study. Critical Care Explorations 2024, 6: e1105. PMID: 38904975, PMCID: PMC11196078, DOI: 10.1097/cce.0000000000001105.Peer-Reviewed Original ResearchConceptsRenal replacement therapyLength of stayHospital length of stayHigher hospital mortalityKetamine infusionTotal hospital costsHospital mortalityVasopressor daysKetamine useVentilator daysSample of U.S. hospitalsRenal replacement therapy useAssociated with higher hospital mortalityDays of mechanical ventilationAssociated with in-hospital mortalityHospital costsManagement of critically ill patientsExtracorporeal membrane oxygenationPropensity Score Matching AnalysisRetrospective cohort studyPremier Healthcare DatabaseDays of hospitalizationDays of intubationMechanically Ventilated PatientsCritically ill patientsEarly prediction of long hospital stay for Intensive Care units readmission patients using medication information
Zhang M, Kuo T. Early prediction of long hospital stay for Intensive Care units readmission patients using medication information. Computers In Biology And Medicine 2024, 174: 108451. PMID: 38603899, PMCID: PMC11385457, DOI: 10.1016/j.compbiomed.2024.108451.Peer-Reviewed Original ResearchConceptsIntensive care unitProlonged ICU LOSAverage doseICU LOSLonger hospital stayReceiver operating characteristic curveLogistic regressionPredicting intensive care unitMedical informationExpected calibration errorSummed dosePatient ageHospital staySupport vector machineCare unitMIMIC-IV databasePatient complicationsCharacteristic curveMedicationRandom forestDosePatient recordsAdmissionReadmission patientsUse of The Risk Assessment and Prediction Tool to Predict Same-day Discharge After Primary Hip and Knee Arthroplasty
Dupont M, Held M, Shah R, Cooper H, Neuwirth A, Hickernell T. Use of The Risk Assessment and Prediction Tool to Predict Same-day Discharge After Primary Hip and Knee Arthroplasty. JAAOS Global Research And Reviews 2024, 8: e22.00269. PMID: 38456719, PMCID: PMC10923310, DOI: 10.5435/jaaosglobal-d-22-00269.Peer-Reviewed Original ResearchConceptsSame-day dischargeTotal knee arthroplastyTotal hip arthroplastyTertiary care centerPreoperative screening toolReceiver operating characteristic curveRAPT scoreScreening toolLogistic regression analysisAssociated with same-day dischargeKnee arthroplastyCutoff valuePreoperative notesPredictive valueCare centerPatientsCharacteristic curveSame-dayDischarge dispositionDischarge planningRegression analysisArthroplastyPositive associationScoresCutoff
2023
Impact of frailty on complications and length of stay after minimally invasive adrenalectomy surgery
Ahuja V, Gibson C, Machado N, King J. Impact of frailty on complications and length of stay after minimally invasive adrenalectomy surgery. Surgery 2023, 175: 336-341. PMID: 38049363, DOI: 10.1016/j.surg.2023.10.023.Peer-Reviewed Original ResearchConceptsFrailty indexInvasive adrenalectomySurgical indicationsBenign diseaseMalignant diseaseMost adverse outcomesStay 2 daysImpact of frailtyThirty-day mortalityLength of stayRelationship of ageAdrenalectomy patientsAdrenalectomy proceduresAdrenalectomy surgeryElective adrenalectomyPerioperative outcomesAdrenal surgeryComplication rateOlder patientsAdrenal diseaseMedian lengthSurgical outcomesAdverse outcomesEndocrine disordersEndocrine diseasesOlder adults with epilepsy and COVID-19: Outcomes in a multi-hospital health system
Ufongene C, Van Hyfte G, Agarwal P, Goldstein J, Mathew B, Navis A, McCarthy L, Kwon C, Gururangan K, Balchandani P, Marcuse L, Naasan G, Singh A, Young J, Charney A, Nadkarni G, Jette N, Blank L, Group S. Older adults with epilepsy and COVID-19: Outcomes in a multi-hospital health system. Seizure 2023, 114: 33-39. PMID: 38039805, PMCID: PMC10841585, DOI: 10.1016/j.seizure.2023.11.018.Peer-Reviewed Original ResearchMeSH KeywordsAgedCOVID-19EpilepsyHospital MortalityHospitalizationHospitalsHumansLength of StayRetrospective StudiesSARS-CoV-2ConceptsInternational Classification of DiseasesLength of stayOlder adultsDischarge dispositionHigher In-Hospital MortalityHealth systemIn-Hospital DeathIn-Hospital MortalityMulti-hospital health systemOdds of in-hospital deathAssociated with increased oddsAssociated with increased odds of in-hospital deathNew York health systemMultivariate logistic regression modelClassification of diseasesConsecutive older patientsAssociated with higher in-hospital mortalityLogistic regression modelsCompare in-hospital outcomesFactors associated with mortalityNon-routine discharge dispositionAssociated with higher ratesOlder peopleInternational ClassificationAdmitted with COVID-19Early observations with an ERAS pathway for thyroid and parathyroid surgery: Moving the goalposts forward
Machado N, Mortlock R, Maduka R, Souza Cunha A, Dyer E, Long A, Canner J, Tanella A, Gibson C, Hyman J, Ogilvie J. Early observations with an ERAS pathway for thyroid and parathyroid surgery: Moving the goalposts forward. Surgery 2023, 175: 114-120. PMID: 37973430, PMCID: PMC10838521, DOI: 10.1016/j.surg.2023.06.052.Peer-Reviewed Original ResearchMeSH KeywordsAnalgesics, OpioidHumansLength of StayMorphine DerivativesPain, PostoperativePostoperative ComplicationsThyroid GlandConceptsSurgery pathwayEnhanced recoverySurgery groupParathyroid surgerySignificant decreasePost-anesthesia care unit lengthAverage daily pain scoreSuperficial cervical plexus blockThyroid/parathyroid surgeryAverage daily morphineDaily pain scoresCervical plexus blockCases 1 yearStandard of careDaily morphineERAS pathwayPostoperative admissionPostoperative antiemeticsPostoperative morphineUnanticipated admissionPain scoresPerioperative outcomesPlexus blockProspective trialPatient group
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