Underrepresentation and exclusion of patients with cardiovascular disease in intensive care randomized controlled trials
Ali T, Grimshaw A, Thomas A, Solomon M, Ross J, Miller P. Underrepresentation and exclusion of patients with cardiovascular disease in intensive care randomized controlled trials. European Heart Journal Acute Cardiovascular Care 2025, 14: 259-267. PMID: 39950988, PMCID: PMC12082296, DOI: 10.1093/ehjacc/zuaf023.Peer-Reviewed Original ResearchContemporary cardiac intensive care unitsRandomized Controlled TrialsIschemic heart diseaseCardiovascular diseaseHeart failureDisciplines of critical care medicineHistory of heart failureProspective randomized controlled trialsHeart diseaseControlled TrialsExclusion criteriaMultivariate logistic regression analysisCardiac intensive care unitProportion of patientsExclusion of patientsComorbid cardiovascular diseaseCardiovascular disease historyIntensive care unitLogistic regression analysisApplication of randomized controlled trialsComplex patient populationGeneral internal medicineCardiovascular disease comorbiditiesMulticenter trialIndependent predictors
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