2025
Serotonin Norepinephrine Reuptake Inhibitor Is Associated With Lower Mortality Among Patients Presenting With Takotsubo Cardiomyopathy.
Shamaki G, Anuforo A, Safiriyu I, Corteville D, Sanghavi M, Shah S, Clark K. Serotonin Norepinephrine Reuptake Inhibitor Is Associated With Lower Mortality Among Patients Presenting With Takotsubo Cardiomyopathy. Journal Of The American Heart Association 2025, 14: e037951. PMID: 40551298, DOI: 10.1161/jaha.124.037951.Peer-Reviewed Original ResearchConceptsSerotonin-norepinephrine reuptake inhibitorsDiagnosis of takotsubo cardiomyopathyTakotsubo cardiomyopathyPropensity score matchingReuptake inhibitorsClinical outcomes of patientsNorepinephrine reuptake inhibitorsReuptake of serotoninScore matchingOutcomes of patientsOpioid-related disordersCocaine-related disordersAssociated with lower mortalityLower mortalityTriNetX Research NetworkTreatment of depressionAssociated with lowered mortalityAcute myocardial infarctionNeuropathic painPresynaptic reuptakeClinical outcomesCardiac arrestPrimary outcomeSecondary outcomesVentricular fibrillationIntravenous thrombolysis for acute ischemic stroke patients with cerebral amyloid angiopathy
Chen H, Colasurdo M, Khunte M, Malhotra A, Gandhi D. Intravenous thrombolysis for acute ischemic stroke patients with cerebral amyloid angiopathy. Journal Of The Neurological Sciences 2025, 475: 123586. PMID: 40561725, DOI: 10.1016/j.jns.2025.123586.Peer-Reviewed Original ResearchAssociated with significantly higher oddsSignificantly higher oddsHigher oddsMultivariate logistic regressionAcute ischemic stroke patientsIn-Hospital MortalityAcute ischemic strokeLogistic regressionAssociated with higher oddsIntravenous thrombolysisDatabase of hospitalizationsAssociated with older agePropensity score matchingSelf-CareBalanced treatment groupsIschemic stroke patientsIntracerebral hemorrhageHome dischargeStroke patientsSecondary outcomesCerebral amyloid angiopathyPrimary outcomeOddsScore matchingHemorrhagic cerebrovascular diseaseEstablishment and application of an RNA-seq-based predictive model for the hourly precision window of implantation (WOI) in patients with recurrent implantation failure
He A, Yang T, Lu S, Zou Y, Wan C, Chen Y, Zhao J, Liu N, Liu D, Li Y, Wang Y, Xu B, Hao J, Fu J, Zhang Q, Wang B, Li Y. Establishment and application of an RNA-seq-based predictive model for the hourly precision window of implantation (WOI) in patients with recurrent implantation failure. Journal Of Assisted Reproduction And Genetics 2025, 1-16. PMID: 40304883, DOI: 10.1007/s10815-025-03468-8.Peer-Reviewed Original ResearchRecurrent implantation failureIntrauterine pregnancy ratePersonalized embryo transferLive birth rateImplantation rateB-hCGEndometrial receptivity testPregnancy ratePropensity score matchingImplant failureB-human chorionic gonadotropinEarly spontaneous abortion rateSpontaneous abortion rateControl groupBirth rateIntrauterine pregnancyPregnancy outcomesEndometrial biopsyEmbryo transferChorionic gonadotropinPregnancyPatientsExperimental groupAbortion rateScore matchingUnderstanding Surgical Management and Outcomes in Mitral Valve Endocarditis
Dzilic E, Niedermayer S, Burri M, Amabile A, Krane M, Vitanova K. Understanding Surgical Management and Outcomes in Mitral Valve Endocarditis. Journal Of Clinical Medicine 2025, 14: 2712. PMID: 40283542, PMCID: PMC12027858, DOI: 10.3390/jcm14082712.Peer-Reviewed Original ResearchMitral valve endocarditisMitral valve repairValve endocarditisValve repairPropensity score matchingValve replacementScore matchingNative mitral valve endocarditisMitral valve replacementRetrospective cohort studyLong-term survivalConsecutive patientsSurgical outcomesValve reconstructionAbscess formationSingle-centerSurgical managementEndocarditisSurgical patientsFollow-upCohort studyPatientsTreatment assignment biasMortality rateSurvivalLong-term evaluation of the timing of corticosteroid therapy in an IgA nephropathy cohort
Hou W, Yang H, Chen P, Tang C, Zhou X, Liu L, Zhu L, Shi S, Lv J, Zhang H. Long-term evaluation of the timing of corticosteroid therapy in an IgA nephropathy cohort. Clinical Kidney Journal 2025, 18: sfaf076. PMID: 40322679, PMCID: PMC12044332, DOI: 10.1093/ckj/sfaf076.Peer-Reviewed Original ResearchEarly therapy groupCorticosteroid therapyHazard ratioPropensity score matchingTherapy groupSteroid initiationSteroid treatmentEGFR slopeIgAN patientsTiming of corticosteroid therapyPatients treated with corticosteroidsLong-term kidney functionEGFR decline >Composite renal outcomeSystemic corticosteroid therapyEarly corticosteroid therapyScore matchingKaplan-Meier curvesTime-averaged proteinuriaImmunoglobulin A nephropathyLong-term outcomesIgA nephropathy cohortProgressive IgANDelayed therapyRenal outcomesSex differences in in-hospital outcomes and readmission rates after percutaneous coronary intervention
Gomez J, Park D, Eder M, An S, Lowenstern A, Kelsey M, Rymer J, Douglas P, Nanna M. Sex differences in in-hospital outcomes and readmission rates after percutaneous coronary intervention. Baylor University Medical Center Proceedings 2025, 38: 159-169. PMID: 39990004, PMCID: PMC11845020, DOI: 10.1080/08998280.2025.2452113.Peer-Reviewed Original ResearchIn-Hospital OutcomesIn-Hospital MortalitySecondary outcomesReadmission ratesOdds of in-hospital mortalityPercutaneous coronary interventionCalculate odds ratiosInpatient percutaneous coronary interventionHazard of readmissionUnited States National Readmission DatabaseIn-Hospital Adverse OutcomesPropensity score matchingHealth systemHospital characteristicsOdds of cardiac arrestSocioeconomic statusReimbursement implicationsSex differencesYears of ageOdds ratioReadmission riskCox proportional-hazardsLogistic regressionIn-Hospital ComplicationsScore matchingThe Use of Acellular Dermal Matrix May Not Increase 30-Day Complications in Direct-to-Implant Breast Reconstruction: A Multi-institutional Analysis of 10,177 Cases.
Knoedler S, Klimitz F, Friedrich S, Schemet L, Broer P, Cherubino M, Könneker S, Kim B, Pomahac B, Kauke-Navarro M. The Use of Acellular Dermal Matrix May Not Increase 30-Day Complications in Direct-to-Implant Breast Reconstruction: A Multi-institutional Analysis of 10,177 Cases. Annals Of Plastic Surgery 2025 PMID: 39874559, DOI: 10.1097/sap.0000000000004234.Peer-Reviewed Original ResearchDirect-to-implant breast reconstructionDirect-to-implantAcellular dermal matrixBreast reconstructionPropensity score matchingHigher risk of short-term complicationsMedical complicationsAmerican College of Surgeons National Surgical Quality Improvement Program databaseSurgeons National Surgical Quality Improvement Program databaseNational Surgical Quality Improvement Program databaseIncreased 30-day complicationsMultivariate analysisRisk of short-term complicationsQuality Improvement Program databaseThirty-day postoperative complicationsSurgical complication rateIncorporation of acellular dermal matrixScore matchingMulti-institutional analysisMulti-institutional databaseShort-term complicationsComplication ratePostoperative complicationsWound dehiscenceNo significant differenceOutcomes in management of locally advanced rectal cancer with total neoadjuvant therapy in an underserved population.
Ganguly A, Paladiya R, Ingawale S, Giri S, Abbagoni V, Thumar J. Outcomes in management of locally advanced rectal cancer with total neoadjuvant therapy in an underserved population. Journal Of Clinical Oncology 2025, 43: 208-208. DOI: 10.1200/jco.2025.43.4_suppl.208.Peer-Reviewed Original ResearchTNT groupTotal neoadjuvant therapyLocally Advanced Rectal CancerAdvanced rectal cancerManagement of locally advanced rectal cancerTumor locationNeoadjuvant therapyConventional therapyRectal cancerCT groupPropensity score matchingLow tumorsHigh tumorNo responsePathologic response to treatmentTreating locally advanced rectal cancerResponse ratePartial response ratePathological response rateScore matchingFisher's exact testResponse to treatmentComplete responseAdjuvant treatmentUnderserved populationsMechanical thrombectomy in elderly stroke patients with low ASPECTS: insights from STAR
Cunningham C, Hubbard Z, Kasem R, Elawady S, Sowlat M, Matsukawa H, Maier I, Jabbour P, Kim J, Wolfe S, T A, Starke R, Psychogios M, Samaniego E, Goyal N, Yoshimura S, Cuellar H, Howard B, Alawieh A, Alaraj A, Ezzeldin M, Romano D, Tanweer O, Mascitelli J, Fragata I, Polifka A, Siddiqui F, Osbun J, Grandhi R, Crosa R, Matouk C, Park M, Levitt M, Brinjikji W, Moss M, Daglioglu E, Williamson R, Navia P, Kan P, De Leacy R, Chowdhry S, Altschul D, Al Kasab S, Spiotta A. Mechanical thrombectomy in elderly stroke patients with low ASPECTS: insights from STAR. Journal Of NeuroInterventional Surgery 2025, 17: e206-e215. PMID: 39855673, DOI: 10.1136/jnis-2024-022677.Peer-Reviewed Original ResearchAlberta Stroke Program Early CT ScoreLow Alberta Stroke Program Early CT ScorePropensity score matchingSymptomatic intracranial hemorrhageEndovascular thrombectomyAnterior circulation large vessel occlusion acute ischemic strokeElderly patientsLVO-AISAssociated with 90-day mortalityRate of atrial fibrillationScore matchingLarge vessel occlusion acute ischemic strokeFirst-pass reperfusionAcute ischemic strokeCT scoreIntracranial hemorrhagePatient selectionMRS scoreAtrial fibrillationClinical factorsFavorable outcomeRecanalization ratePrimary outcomeMechanical thrombectomyPatients
2024
Bipolar disorder among individuals with atopic dermatitis: a case–control study in the All of Us Research Program
Wride A, Chen G, Fan R, Leasure A, Jones S, Levey D, Damsky W, Cohen J. Bipolar disorder among individuals with atopic dermatitis: a case–control study in the All of Us Research Program. Clinical And Experimental Dermatology 2024, 50: 760-763. PMID: 39425681, DOI: 10.1093/ced/llae451.Peer-Reviewed Original ResearchPersonalized embryo transfer guided by rsERT with hourly precision improves pregnancy outcomes in patients with a receptive window of implantation: a pilot study
Yang T, Hou Z, Zhang Q, Zhao J, Liu N, Liu D, Li Y, Wang Y, Xu B, Zou Y, Wan C, Li Y. Personalized embryo transfer guided by rsERT with hourly precision improves pregnancy outcomes in patients with a receptive window of implantation: a pilot study. Journal Of Assisted Reproduction And Genetics 2024, 41: 2657-2665. PMID: 39254797, PMCID: PMC11534956, DOI: 10.1007/s10815-024-03246-y.Peer-Reviewed Original ResearchIntrauterine pregnancy ratePersonalized embryo transferWindow of implantationEmbryo transferPropensity score matchingImplantation rateET groupCenter for Reproductive MedicineResultsBefore propensity score matchingImplant failure rateGroup compared to controlsRetrospective pilot studyConventional embryo transferMultiple-pregnancy ratesEndometrial receptivity testCentral South UniversityPregnancy outcomesTransferred embryosPilot studyPregnancy ratePatientsSouth UniversityReproductive medicineScore matchingConfounding factorsMDS-772 Time Toxicity for Patients Receiving Oral Versus Parenteral Hypomethylating Agents for Myelodysplastic Syndromes/Neoplasms
Zeidan A, Olopoenia A, Costantino H, Modi K, Salimi T, Washington T, Krenitsky J, Epstein R. MDS-772 Time Toxicity for Patients Receiving Oral Versus Parenteral Hypomethylating Agents for Myelodysplastic Syndromes/Neoplasms. Clinical Lymphoma Myeloma & Leukemia 2024, 24: s406. DOI: 10.1016/s2152-2650(24)01382-x.Peer-Reviewed Original ResearchHMA therapyRetrospective analysis of adult patientsAnalysis of adult patientsRoute of administrationMedian life expectancyPropensity score matchingHypomethylating agentsMDS treatmentBurden of treatmentAdult patientsPatient cohortInfusion dayParenteral treatmentMatched CohortResults PatientsRetrospective analysisOlder patientsEmergency room visitsCancer therapyHMA treatmentParenteral administrationTherapyPatientsOutpatient settingScore matchingNormothermic Machine Perfusion Is Associated With Improvement in Mortality and Graft Failure in Donation After Cardiac Death Liver Transplant Recipients in the United States
Okumura K, Dhand A, Misawa R, Sogawa H, Veillette G, Nishida S. Normothermic Machine Perfusion Is Associated With Improvement in Mortality and Graft Failure in Donation After Cardiac Death Liver Transplant Recipients in the United States. Transplantation Direct 2024, 10: e1679. PMID: 38988687, PMCID: PMC11230788, DOI: 10.1097/txd.0000000000001679.Peer-Reviewed Original ResearchNormothermic machine perfusion groupNormothermic machine perfusionLiver transplantationLT recipientsGraft survivalPropensity score matchingOverall survivalGraft failureDCD LT recipientsTwo-year overall survivalEnd-stage liver disease scoreMultivariate Cox regression analysisAdult LT recipientsScore matchingLiver transplant recipientsLiver Disease scoreCox regression analysisMachine perfusionUnited Network for Organ SharingUtilization of donationPosttransplant patientsTransplant recipientsAssociated with improvementsNon-MPSOlder donorsTime toxicity for patients receiving oral versus parenteral hypomethylating agents for myelodysplastic syndromes/neoplasms (MDS).
Epstein R, Zeidan A, Olopoenia A, Costantino H, Modi K, Salimi T, Washington T, Krenitsky J. Time toxicity for patients receiving oral versus parenteral hypomethylating agents for myelodysplastic syndromes/neoplasms (MDS). Journal Of Clinical Oncology 2024, 42: 6568-6568. DOI: 10.1200/jco.2024.42.16_suppl.6568.Peer-Reviewed Original ResearchHMA therapyHypomethylating agentsRetrospective analysis of adult patientsAnalysis of adult patientsEmergency roomRoute of administrationTime burdenMedian life expectancyPropensity score matchingMDS treatmentBurden of treatmentAdult patientsParenteral treatmentPatient cohortInfusion dayRetrospective analysisCancer therapyPatientsTherapyOutpatient settingScore matchingTreatment groupsCohortHealthcare daysOutpatient visitsCerebral embolic protection device utilization and outcomes in transcatheter aortic valve replacement: A nationally representative propensity matched analysis
Altibi A, Alhuneafat L, Jabri A, Al-Abdouh A, Ghanem F. Cerebral embolic protection device utilization and outcomes in transcatheter aortic valve replacement: A nationally representative propensity matched analysis. Cardiovascular Revascularization Medicine 2024, 67: 112-114. PMID: 38653674, DOI: 10.1016/j.carrev.2024.04.003.Peer-Reviewed Original ResearchTranscatheter aortic valve replacementCerebral embolic protection devicesAortic valve replacementPropensity score matchingNational Readmission DatabaseIn-Hospital StrokeValve replacementIn-HospitalPeriprocedural strokeOdds ratioTranscatheter aortic valve replacement patientsTransfemoral transcatheter aortic valve replacementPropensity score matched cohortAssociated with decreased riskScore matchingPropensity matched analysisRisk of periprocedural strokeRisk of in-hospital strokeAcute kidney injuryTAVR admissionsIn-Hospital MortalityConfidence intervalsOutcomes post-TAVRAssociated with reduced oddsEmbolic protection devices
2023
Impact of same-admission percutaneous coronary intervention on periprocedural outcomes of transcatheter aortic valve implantation
Park D, An S, Arif A, Saini A, Golzar Y. Impact of same-admission percutaneous coronary intervention on periprocedural outcomes of transcatheter aortic valve implantation. Baylor University Medical Center Proceedings 2023, 37: 7-13. PMID: 38174009, PMCID: PMC10761096, DOI: 10.1080/08998280.2023.2273742.Peer-Reviewed Original ResearchAssociated with higher oddsHigher oddsPercutaneous coronary interventionCompare in-hospital outcomesAssociated with longer lengthNational Inpatient SamplePropensity score matchingCoronary artery diseaseIn-Hospital MortalityIn-Hospital OutcomesAcute myocardial infarctionArtery diseaseInpatient SampleScore matchingCoronary interventionHospital costsCardiac arrestTranscatheter aortic valve implantationCurrent guidelinesOddsMyocardial infarctionInterventionLonger lengthControl groupHospital
2022
Outcomes of Liver Transplantation Using Machine Perfusion in Donation after Cardiac Death vs Brain Death in the US.
Okumura K, Dhand A, Misawa R, Sogawa H, Veillette G, Nishida S. Outcomes of Liver Transplantation Using Machine Perfusion in Donation after Cardiac Death vs Brain Death in the US. Journal Of The American College Of Surgeons 2022, 236: 73-80. PMID: 36519910, DOI: 10.1097/xcs.0000000000000425.Peer-Reviewed Original ResearchConceptsLiver transplantationPropensity score matchingMachine perfusionCardiac deathIndependent risk factor of mortalityEnd-stage liver disease scoreOutcome of liver transplantationRisk factors of mortalityAdult LT recipientsMedian recipient ageScore matchingIndependent risk factorLiver Disease scoreMedian donor ageCox regression analysisDCD groupFactors of mortalityHigher prevalence of diabetesUnited Network for Organ SharingBrain deathPrevalence of diabetesLT recipientsRecipient ageLT outcomesTransplant recipientsImpact of cardiac and noncardiac cirrhosis on coronary revascularization outcomes from the National Inpatient Sample, 2016 to 2018
Park D, An S, Warraich M, Aldeen Z, Maghari I, Khanal S, Arif A, Almoghrabi A. Impact of cardiac and noncardiac cirrhosis on coronary revascularization outcomes from the National Inpatient Sample, 2016 to 2018. Baylor University Medical Center Proceedings 2022, 36: 195-200. PMID: 36876247, PMCID: PMC9980685, DOI: 10.1080/08998280.2022.2139989.Peer-Reviewed Original ResearchCoronary Artery Bypass GraftingCoronary artery bypass grafting cohortIn-Hospital MortalityPercutaneous coronary interventionAcute coronary syndromeHigher In-Hospital MortalityNational Inpatient SampleCardiac cirrhosisCoronary revascularizationAssociated with higher in-hospital mortalityInpatient SamplePercutaneous coronary intervention cohortArtery Bypass GraftingPeriprocedural morbiditySignificant comorbiditiesCoronary syndromeLiver cirrhosisBypass GraftingRevascularization outcomesPrimary outcomeCirrhosisNo cirrhosisCoronary interventionPatientsScore matchingAbstract 13931: Comparison of Inpatient Outcomes of Transcatheter Aortic Valve Replacement in Bicuspid versus Tricuspid Aortic Valve Stenosis: An Insight From National Inpatient Sample
Poudyal A, Park D, Khanal S, Shrestha P, Sharma B, Karki S, Vij A. Abstract 13931: Comparison of Inpatient Outcomes of Transcatheter Aortic Valve Replacement in Bicuspid versus Tricuspid Aortic Valve Stenosis: An Insight From National Inpatient Sample. Circulation 2022, 146: a13931-a13931. DOI: 10.1161/circ.146.suppl_1.13931.Peer-Reviewed Original ResearchTricuspid aortic valve patientsBicuspid aortic valvePermanent pacemaker placementTricuspid aortic valveLength of hospital stayBicuspid aortic valve patientsNo significant differenceParavalvular leakEmbolic strokePropensity score matchingAortic stenosisSignificant differenceAortic valveOutcomes of transcatheter aortic valve replacementTricuspid aortic valve groupTricuspid aortic valve stenosisLong-term follow-upTranscatheter aortic valve replacementRate of embolic strokeAortic valve anatomyScore matchingAortic valve replacementSevere aortic stenosisAortic valve stenosisNational Inpatient Sample databaseIn-hospital prognosis of malignancy-related pulmonary embolism: an analysis of the national inpatient sample 2016–2018
Park D, An S, Kashoor I, Ezegwu O, Gupta S. In-hospital prognosis of malignancy-related pulmonary embolism: an analysis of the national inpatient sample 2016–2018. Journal Of Thrombosis And Thrombolysis 2022, 54: 630-638. PMID: 35876942, DOI: 10.1007/s11239-022-02684-8.Peer-Reviewed Original ResearchConceptsOdds of in-hospital mortalityIn-Hospital MortalityAssociated with higher oddsPulmonary embolismNational Inpatient SamplePropensity score matchingEsophageal cancerLung cancerHigher oddsInpatient SamplePrognosis of PEScore matchingDiagnosis of PEClinically relevant covariatesPrimary diagnosis of PEMalignant groupOvarian cancerRetrospective studyMalignancyPrimary diagnosisRelevant covariatesCancerOddsPatientsMortality
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