2025
Emergency Department Implementation of a Multimodal Electronic Health Record–Integrated Clinical Intervention for High-Sensitivity Troponin Testing Increases Diagnostic Efficiency
Sangal R, Iscoe M, Rothenberg C, Possick S, Taylor R, Safdar B, Desai N, Rhodes D, Venkatesh A. Emergency Department Implementation of a Multimodal Electronic Health Record–Integrated Clinical Intervention for High-Sensitivity Troponin Testing Increases Diagnostic Efficiency. Journal Of The American College Of Emergency Physicians Open 2025, 6: 100202. DOI: 10.1016/j.acepjo.2025.100202.Peer-Reviewed Original ResearchEmergency departmentAcute myocardial infarction diagnosisTroponin testingED dischargeMyocardial infarction diagnosisAssociated with lower oddsAccelerated diagnostic protocolPhysician practice variationAcute coronary syndromeInfarction diagnosisChest pain evaluationMultivariate logistic regressionSuspected acute coronary syndromePostintervention periodDownstream testingPhysician practicesPreintervention periodED dispositionLower oddsCoronary syndromeDecreased oddsIncreased oddsPractice variationED patientsHs-cTnTJoint Exposure to Ozone and Temperature and Acute Myocardial Infarction Among Adults Aged 18 to 64 Years in the United States.
Chu L, Wang R, Gross C, Wei J, Lu Y, Krumholz H, Ma X, Chen K. Joint Exposure to Ozone and Temperature and Acute Myocardial Infarction Among Adults Aged 18 to 64 Years in the United States. Circulation 2025 PMID: 40458867, DOI: 10.1161/circulationaha.124.073614.Peer-Reviewed Original ResearchIncident acute myocardial infarctionAcute myocardial infarctionIncreased oddsRisk of acute myocardial infarctionHigher risk of acute myocardial infarctionProbability of acute myocardial infarctionOccurrence of acute myocardial infarctionRandom-effects meta-analysisCase-crossover studyMultivariate random-effects meta-analysisExposure to ozoneRegion-specific estimatesMyocardial infarctionStatistical interaction termsAmbient ozone pollutionPrevention strategiesUnited StatesJoint exposureMeta-analysisAdult ageYoung adultsHigh riskAdultsOddsInteraction termsOptimism moderates the relationship between inflammatory polygenic risk and major depressive disorder in U.S. Military veterans
Fischer I, Overstreet C, Cabrera-Mendoza B, Qiu D, Krystal J, Polimanti R, Gelernter J, Pietrzak R. Optimism moderates the relationship between inflammatory polygenic risk and major depressive disorder in U.S. Military veterans. The World Journal Of Biological Psychiatry 2025, 26: 189-198. PMID: 40343713, DOI: 10.1080/15622975.2025.2498352.Peer-Reviewed Original ResearchConceptsMajor depressive disorderU.S. military veteransPolygenic risk scoresDepressive disorderMilitary veteransMajor depressive disorder riskPsychosocial moderatorsMDD screeningLow optimismPolygenic riskHigher optimismNationally Representative SampleTrauma burdenPredisposition to inflammationStandard deviation increaseUK BiobankGenetic riskPathway-based analysisVeteransIncreased oddsRepresentative sampleRisk scoreMedical conditionsInflammatory biomarkersChronic inflammationFactors Associated with Preoperative Attrition from a Large, Racially and Ethnically Representative Bariatric Program in the USA: A Single-Center Retrospective, Cohort Study
Hamid S, Butensky S, Graetz E, Olivares M, Schwartz J, Schneider E, Ghiassi S, Gibbs K. Factors Associated with Preoperative Attrition from a Large, Racially and Ethnically Representative Bariatric Program in the USA: A Single-Center Retrospective, Cohort Study. Obesity Surgery 2025, 35: 2390-2394. PMID: 40295326, DOI: 10.1007/s11695-025-07884-8.Peer-Reviewed Original ResearchConceptsFactors associated with attritionAssociated with decreased oddsObesity-related diseasesHispanic ethnicitySocial Vulnerability IndexStudy samplePreoperative attritionElectronic health recordsAcademic health systemAssociated with increased oddsAssociated with attritionRegional-level factorsMultivariate logistic regressionHealth recordsNon-HispanicHealth systemCompared individual-US populationIncreased oddsSurgical treatment of obesityCohort studyMedicare insuranceLogistic regressionMedicareOddsHow Cannabis Use is Associated with the Physical and Mental Health of Older Adults: A US Population-Based Study
You E, Sarkar S, Pietrzak R, Monin J, Poghosyan H. How Cannabis Use is Associated with the Physical and Mental Health of Older Adults: A US Population-Based Study. International Journal Of Mental Health And Addiction 2025, 1-22. DOI: 10.1007/s11469-025-01475-5.Peer-Reviewed Original ResearchCannabis useMental healthDaily cannabis usersPhysical healthDays of poor physical healthBehavioral Risk Factor Surveillance SystemRisk Factor Surveillance SystemIncreased oddsUS population-based studyAssociated with poor healthPhysical and Mental HealthPoor physical healthLack health insurance coverageMultivariate multinomial logistic regression analysisCannabis usersPopulation-based studyEvidence-based guidelinesMultinomial logistic regression analysisHealth insurance coverageLogistic regression analysisPoor healthOlder adultsCannabisInsurance coveragePromote awarenessImpact of an electronically‐integrated clinical pathway on hospital initiation of medications for alcohol use disorder and subsequent hospital utilization
Cole K, Weimer M, Wang K, Fiellin D, Advani A, Shah N, Zemaitis C, Rhodes D. Impact of an electronically‐integrated clinical pathway on hospital initiation of medications for alcohol use disorder and subsequent hospital utilization. Journal Of Hospital Medicine 2025 PMID: 40221929, DOI: 10.1002/jhm.70049.Peer-Reviewed Original ResearchClinical pathwayAlcohol use disorderED returnUse disorderHospital-based strategiesAcademic medical centerTertiary academic medical centerDays of dischargeHospital InitiativeInitiation of medicationHealth systemHospital utilizationMultiple barriersIncreased oddsConsecutive adult inpatientsHospital dischargeSecondary outcomesIncreased low ratesAdult inpatientsMedical CenterTreatment initiationHospitalVoluntary useReadmissionMedicationPrevalence and determinants of cigarette-cannabis co-use among US cancer survivors
Raziani Y, Sarkar S, Zaidi M, Poghosyan H. Prevalence and determinants of cigarette-cannabis co-use among US cancer survivors. Journal Of Cancer Survivorship 2025, 1-12. PMID: 40156654, DOI: 10.1007/s11764-025-01789-2.Peer-Reviewed Original ResearchCancer survivorsDays of poor physical healthSubgroups of cancer survivorsBehavioral Risk Factor Surveillance SystemPoor mental health daysRisk Factor Surveillance SystemUS cancer survivorsAdult cancer survivorsMental health daysMultinomial multivariable logistic regression modelPoor physical healthPopulation-based dataMultivariate logistic regression modelIndividual-level factorsConclusionsThe study findingsCo-useLogistic regression modelsHealth daysPhysical healthYoung survivorsLess educationIncreased oddsSelf-ReportCigarette useSurveillance systemThe association between physical multimorbidity and fall-related injury among adults aged ≥ 50 years from low- and middle-income countries
Smith L, López Sánchez G, Shin J, Oh H, Kostev K, Tully M, Barnett Y, Butler L, Veronese N, Soysal P, Jacob L, Koyanagi A. The association between physical multimorbidity and fall-related injury among adults aged ≥ 50 years from low- and middle-income countries. European Journal Of Ageing 2025, 22: 12. PMID: 40107990, PMCID: PMC11923311, DOI: 10.1007/s10433-025-00848-y.Peer-Reviewed Original ResearchFall-related injuriesFall riskChronic conditionsOlder adultsAssociated with increased fall riskChronic physical conditionsCommunity-based dataSelf-reported informationMiddle-income countiesMiddle-income countriesHigh-income countriesMultivariate logistic regressionPhysical multimorbidityMultimorbidityIncreased oddsGlobal ageLMICsLogistic regressionPotential mediatorsMediation analysisAdultsOddsAssociationPhysical conditionsInjuryOutcomes following single level posterior lumbar fusion in patients with systemic and discoid lupus: A retrospective national database study
Dhodapkar M, Halperin S, Day W, Saifi C, Rubio D, Koumpouras F, Grauer J, Varthi A. Outcomes following single level posterior lumbar fusion in patients with systemic and discoid lupus: A retrospective national database study. North American Spine Society Journal (NASSJ) 2025, 22: 100604. PMID: 40487382, PMCID: PMC12141882, DOI: 10.1016/j.xnsj.2025.100604.Peer-Reviewed Original ResearchPosterior lumbar fusionSystemic lupus erythematosusDiscoid lupus erythematosusSingle-level posterior lumbar fusionPostoperative adverse eventsMinor adverse eventsAdverse eventsIncreased oddsLupus erythematosusLumbar fusionDiagnosis of discoid lupus erythematosusCohort of systemic lupus erythematosusLevel posterior lumbar fusionsMultivariate analysisDiagnosis of systemic lupus erythematosusDiscoid lupus erythematosus patientsUrinary tract infectionPerioperative adverse outcomesSurgical site infectionAcute kidney injuryDeep vein thrombosisNational database studyHistory of infectionSampled adult patientsMultivariate logistic regressionLong-Term Courses of Posttraumatic Growth in Survivors of Hurricane Katrina
Preston J, Lowe S, Rhodes J. Long-Term Courses of Posttraumatic Growth in Survivors of Hurricane Katrina. Traumatology An International Journal 2025, 31: 116-126. DOI: 10.1037/trm0000497.Peer-Reviewed Original ResearchPosttraumatic growthAssociated with membershipIncreased PTGDecreasing PTGPosttraumatic growth trajectoriesPerceived Social SupportIncreased odds of membershipOdds of membershipStressor scoresPositive religious copingPsychosocial resourcesSocial supportSense of purposeSmall body of literaturePredisaster dataLow-incomeIncreased oddsFactors associated with stabilityBlack mothersReligious copingClinical interventionsTrauma eventsNeighborhood satisfactionSurvivorsTrauma survivorsCumulative disaster exposure and hypertension among mothers who survived Hurricane Katrina
Meadows M, Desai M, Zacher M, Lowe S. Cumulative disaster exposure and hypertension among mothers who survived Hurricane Katrina. Environmental Research Health 2025, 3: 025005. PMID: 39968533, PMCID: PMC11831098, DOI: 10.1088/2752-5309/adb32c.Peer-Reviewed Original ResearchPsychological distressHurricane exposureAdverse physical health outcomesDisaster exposurePhysical health outcomesLow-income mothersImpact mental healthShort-term health impactsHurricane KatrinaExposure to hypertensionHealth outcomesChronic conditionsPhysical healthMental healthHypertension oddsHypertension riskIncreased oddsVulnerable populationsSurvey wavesLogistic regressionCumulative exposureHealth impactsPotential mediatorsExposure to hurricanesPost-KatrinaP-1415. Social Determinants of Health and Side Effects Significantly Predict Pre-Exposure Prophylaxis (PrEP) Preferences for Every 2 Month Long-Acting Injectable vs. Daily Oral PrEP among Cisgender Women in the United States and the Dominican Republic
Kerrigan D, Scott R, O’Rourke A, Galai N, Karver T, Davis W, Metzner A, Oglesby A, Moriarty P, Taggart T, Barrington C, Gomez H, Perez M, Donastorg Y. P-1415. Social Determinants of Health and Side Effects Significantly Predict Pre-Exposure Prophylaxis (PrEP) Preferences for Every 2 Month Long-Acting Injectable vs. Daily Oral PrEP among Cisgender Women in the United States and the Dominican Republic. Open Forum Infectious Diseases 2025, 12: ofae631.1590. PMCID: PMC11777370, DOI: 10.1093/ofid/ofae631.1590.Peer-Reviewed Original ResearchPre-exposure prophylaxisLong-actingFemale sex workersSocial determinantsCisgender womenSocial determinants of healthHIV diagnosis ratesDaily oral PrEPDeterminants of healthBlack cisgender womenLow pre-exposure prophylaxisCross-sectional surveyOral PrEPUnited StatesHIV disparitiesWhite cisgender womenHIV inequitiesSide effectsIncreased oddsDiagnosis rateHIVPrEP preferencesDominican RepublicPrEPSex workersVascular Quality Initiative assessment of compliance with Society for Vascular Surgery Practice Guidelines for the endovascular management of claudication
Iannuzzi J, Animilli S, Simons J, Tonnessen B, Koleilat I, Indes J, Conte M, Eldrup-Jorgensen J. Vascular Quality Initiative assessment of compliance with Society for Vascular Surgery Practice Guidelines for the endovascular management of claudication. Journal Of Vascular Surgery 2025, 81: 1155-1163. PMID: 39824263, DOI: 10.1016/j.jvs.2025.01.007.Peer-Reviewed Original ResearchManagement of claudicationHospital-level variationGuideline releaseIncreased odds of smokingArea Deprivation IndexUptake of guidelinesChanges to clinical practiceOdds of smokingMedical managementSociety for Vascular SurgeryCases of claudicationHigh-grade recommendationsAlign careDeprivation indexImprove carePreoperative smoking cessationSmoking cessationMedical therapySocial deprivationDecreased oddsIncreased oddsSecondary analysisStent usePost-procedural recommendationsPractice guidelinesCharacterization of trends in preoperative hemoglobin A1c testing prior to metabolic and bariatric surgery: a retrospective, observational study
Hamid S, Graetz E, Zolfaghari E, Schultz K, Schneider E, Gibbs K. Characterization of trends in preoperative hemoglobin A1c testing prior to metabolic and bariatric surgery: a retrospective, observational study. Perioperative Medicine 2025, 14: 3. PMID: 39789653, PMCID: PMC11720298, DOI: 10.1186/s13741-024-00483-8.Peer-Reviewed Original ResearchRobotic Roux-en-Y gastric bypassBariatric surgeryDiabetes statusSleeve gastrectomyA1c testingRoux-en-Y gastric bypassIncreased oddsPreoperative Hemoglobin A1cDemographic characteristics of patientsCharacteristics of patientsNon-insulin-dependent diabetesInsulin-dependent patientsBaseline diabetes statusLogistic regression analysisSleep apneaCardiopulmonary comorbiditiesAmerican Society of MetabolicGastric bypassMBSAQIP databaseClinical factorsHemoglobin A1c testingMBS patientsSociety recommendationsHemoglobin A1cDependent patients
2024
Work-Related Physical Discomfort and Ergonomics Among Speech-Language Pathologists Performing Flexible Endoscopic Evaluations of Swallowing.
Keltz A, Leydon C, Vernarelli J, Livecchi D, Lerner M. Work-Related Physical Discomfort and Ergonomics Among Speech-Language Pathologists Performing Flexible Endoscopic Evaluations of Swallowing. American Journal Of Speech-Language Pathology 2024, 34: 559-570. PMID: 39700466, DOI: 10.1044/2024_ajslp-24-00258.Peer-Reviewed Original ResearchConceptsSpeech-language pathologistsPhysical discomfortFlexible endoscopic evaluationHealth care professionalsWork environmentSpeech-LanguageCare professionalsEndoscopic evaluation of swallowingMusculoskeletal symptomsYears of experienceErgonomic trainingEvaluation of swallowingDysphagia assessmentIncreased oddsFlexible endoscopic evaluation of swallowingLogistic regressionSuboptimal ergonomicsSpearman rank correlationPhysical challengesWell-beingParticipantsDemographicsDiscomfortRank correlationEquipment factorsA Nationally Representative Analysis of Substance Use and Sexual Health Correlates Associated with HIV and STI Testing among Adolescents
Weerakoon S, Srikanth N, Aivadyan C, Takenaka B, Rose R, Rutledge J, Wan X, Opara I. A Nationally Representative Analysis of Substance Use and Sexual Health Correlates Associated with HIV and STI Testing among Adolescents. AIDS And Behavior 2024, 29: 919-932. PMID: 39661294, DOI: 10.1007/s10461-024-04575-w.Peer-Reviewed Original ResearchOdds of HIVSTI testingYouth Risk Behavior Surveillance SystemIncreased odds of HIVSexual healthIncreased oddsCDC's Youth Risk Behavior Surveillance SystemOdds of HIV testingStepwise multivariate logistic regression modelsSubstance use behaviorsLifetime cocaine useSubstance useMultivariate logistic regression modelNationally representative analysisBehavior Surveillance SystemLogistic regression modelsPrescription drug misuseHIV/STI testingTailored HIVHIV testingSex of sexual partnersUnited StatesCocaine useHealth correlatesTesting servicesImpact of Atopic Dermatitis (Eczema) and Its Treatment on the Risk of Adverse Events Following Total Knee Arthroplasty
Smith-Voudouris J, Dhodapkar M, Halperin S, Cohen J, Grauer J. Impact of Atopic Dermatitis (Eczema) and Its Treatment on the Risk of Adverse Events Following Total Knee Arthroplasty. JAAOS Global Research And Reviews 2024, 8: e23.00267. PMID: 39436712, PMCID: PMC11498930, DOI: 10.5435/jaaosglobal-d-23-00267.Peer-Reviewed Original ResearchConceptsAtopic dermatitisAdverse eventsOdds of pneumoniaTotal knee arthroplastyPerioperative outcomes of patientsModerate-to-severe diseaseIncreased oddsEmergency departmentUrinary tract infectionChronic inflammatory skin conditionOutcomes of patientsLog-rank testRisk of adverse eventsInflammatory skin conditionIncreased odds of pneumoniaKnee arthroplastyTotal knee arthroplasty patientsPerioperative outcomesImmunosuppressive medicationsTract infectionsAggregate adverse eventsAdult patientsImpact of atopic dermatitisPatient characteristicsMultivariate analysisBipolar disorder among individuals with atopic dermatitis: a case–control study in the All of Us Research Program
Wride A, Chen G, Fan R, Leasure A, Jones S, Levey D, Damsky W, Cohen J. Bipolar disorder among individuals with atopic dermatitis: a case–control study in the All of Us Research Program. Clinical And Experimental Dermatology 2024, 50: 760-763. PMID: 39425681, DOI: 10.1093/ced/llae451.Peer-Reviewed Original ResearchFunctional Connectivity Relationships to Longitudinal Motor Outcomes Differ in Very Preterm Children With and Without Brain Injury
Cyr P, Lean R, Kenley J, Kaplan S, Meyer D, Neil J, Alexopoulos D, Brady R, Shimony J, Rodebaugh T, Rogers C, Smyser C. Functional Connectivity Relationships to Longitudinal Motor Outcomes Differ in Very Preterm Children With and Without Brain Injury. Neurology Clinical Practice 2024, 15: e200397. PMID: 39439574, PMCID: PMC11492901, DOI: 10.1212/cpj.0000000000200397.Peer-Reviewed Original ResearchTerm-equivalent ageVery preterm childrenVery pretermChildren born very pretermBayley Scales of Infant DevelopmentMotor deficitsObservational cohort studyBrain injuryLongitudinal observational cohort studyAge 2 yearsAge 5 yearsStructural MRI findingsFine motor scoresNeonatal periodMRI findingsFunctional connectivityBayley ScalesFollow-upCohort studySD decreaseIncreased oddsInjured groupOutcome differencesMotor scoresUninjured groupAssociation between Left Ventricular Geometry, Systolic Ejection Time, and Estimated Glomerular Filtration Rate in Ambulatory Patients with Preserved Left Ventricular Ejection Fraction
Goeddel L, Navarrete S, Waldron N, D’Amiano A, Faraday N, Lima J, Parikh C, Bandeen-Roche K, Hays A, Brown C. Association between Left Ventricular Geometry, Systolic Ejection Time, and Estimated Glomerular Filtration Rate in Ambulatory Patients with Preserved Left Ventricular Ejection Fraction. Cardiology 2024, 1-11. PMID: 39353411, PMCID: PMC11958786, DOI: 10.1159/000541725.Peer-Reviewed Original ResearchLeft ventricular ejection fractionTrans thoracic echocardiographyIncreased RWTRelative wall thicknessChronic kidney diseaseLeft ventricular ejection timeSubclinical systolic dysfunctionVentricular ejection fractionCardiac functionSystolic dysfunctionEjection fractionSystolic functionClinical outcomesPRESERVED LEFT VENTRICULAR EJECTION FRACTIONAmbulatory patientsAssociated with adverse clinical outcomesMeasures of LV geometryEjection timeAssociated with chronic kidney diseaseIncreased oddsMeasures of cardiac functionLV relative wall thicknessSubclinical cardiac dysfunctionIncreased odds of CKDOdds of chronic kidney disease
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