2025
Adolescent extracurricular activities and perception of risk of harm from binge drinking
Szapary C, Meyer J, Fernandes C, Boomer T, Fiellin L, Aneni K. Adolescent extracurricular activities and perception of risk of harm from binge drinking. PLOS Mental Health 2025, 2: e0000278. PMID: 40510398, PMCID: PMC12162072, DOI: 10.1371/journal.pmen.0000278.Peer-Reviewed Original ResearchWeekly binge drinkingRisk of harmPerception of riskBinge drinkingPreventing excessive alcohol consumptionSchool-BasedNumerous adverse health consequencesMultivariate logistic regression modelUnderage binge drinkingCommunity-based activitiesCross-sectional analysisCross-sectional analysis of adolescentsAdverse health consequencesLogistic regression modelsExcessive alcohol consumptionNo significant associationAnalysis of adolescentsPolicy-level supportSchool-based activitiesPreventive interventionsHealth datasetsAlcohol consumptionHealth consequencesRelevant covariatesPrimary outcome
2024
Effect of polypharmacy and potentially inappropriate medications on physical functional decline among older adults with advanced cancer receiving systemic treatment
Mohamed M, Juba K, Awad H, Flannery M, Culakova E, Wells M, Cacciatore J, Jensen-Battaglia M, Mohile S, Ramsdale E. Effect of polypharmacy and potentially inappropriate medications on physical functional decline among older adults with advanced cancer receiving systemic treatment. Supportive Care In Cancer 2024, 32: 674. PMID: 39294452, PMCID: PMC12093274, DOI: 10.1007/s00520-024-08877-6.Peer-Reviewed Original ResearchConceptsShort Physical Performance BatteryPhysical function outcomesPhysical function declineInstrumental ADLOlder adultsAssociated with increased riskAdvanced cancerRisk of IADL declineFunctional declinePhysical Performance BatteryInstrumental ADL scoresVulnerable older adultsSystemic treatmentMethodsThis secondary analysisFunctional outcomesEffects of polypharmacyADL declineIADL declinePerformance BatteryADL scoreBeers criteriaMedication useMonths of treatment initiationRelevant covariatesScreening tool
2023
Association of Optimism, Causal Thinking, and Karma Beliefs with PTSD and Depression 8 Years After the Tsunami in Sri Lanka
Zhang X, Hwang J, Ranasinghe P, Ramadasa U, Levy B, Ranasinghe P. Association of Optimism, Causal Thinking, and Karma Beliefs with PTSD and Depression 8 Years After the Tsunami in Sri Lanka. International Journal Of Applied Positive Psychology 2023, 9: 367-379. DOI: 10.1007/s41042-023-00124-3.Peer-Reviewed Original ResearchAssociation of optimismBetter self-reported healthSelf-reported healthPsychological healthLogistic regression modelsLong-term psychological healthCausal thinkingHigh riskHealth outcomesHigh mortalityRelevant covariatesPTSD symptomsDepressionLower depressionPTSDPsychological traumaTraumaHealthInternal attribution styleAssociationRegression modelsDirect exposurePsychological predictorsAttribution styleExposureImplicit and Explicit Dehumanization of Older Family Members: Novel Determinants of Elder Abuse Proclivity
Chang E, Monin J, Isenberg N, Zelterman D, Levy B. Implicit and Explicit Dehumanization of Older Family Members: Novel Determinants of Elder Abuse Proclivity. Stigma And Health 2023, 8: 40-48. PMID: 37092028, PMCID: PMC10120856, DOI: 10.1037/sah0000370.Peer-Reviewed Original ResearchExplicit dehumanizationElder abuseSelf-reported factorsOlder personsPsychological factorsOlder family membersCare-recipient healthDehumanizationFamily caregiversCurrent studyCaregiver burdenAbuseMost researchCaregiversProclivityWeb-based surveyRelevant covariatesPersonsCaregiver-based interventionsFamily membersVictimsHealthInterventionRelianceNovel determinant
2022
Association Between Depressive Symptoms and Cardiac Structure and Function in a Peruvian Population
Santiago C, Peña M, Brown T, Shakil S, Januzzi J, Velazquez E, Miranda J, Rivera D, Checkley W. Association Between Depressive Symptoms and Cardiac Structure and Function in a Peruvian Population. Global Heart 2022, 17: 78. PMID: 36382157, PMCID: PMC9615600, DOI: 10.5334/gh.981.Peer-Reviewed Original ResearchConceptsSignificant depressive symptomsDepressive symptomsHeart failureCardiac structureTransthoracic echocardiographyEpidemiological Studies Depression ScaleCRONICAS Cohort StudyDiastolic relaxation velocityCause of disabilityMultivariable linear regressionNon-depressed subjectsCohort studyEchocardiographic measuresMiddle-income countriesWorse outcomesDepressive disorderDepression ScaleCardiac diseaseRelaxation velocityDepression symptomsNon-depressed participantsSymptomsPeruvian populationRelevant covariatesAdult participantsIn-hospital prognosis of malignancy-related pulmonary embolism: an analysis of the national inpatient sample 2016–2018
Park D, An S, Kashoor I, Ezegwu O, Gupta S. In-hospital prognosis of malignancy-related pulmonary embolism: an analysis of the national inpatient sample 2016–2018. Journal Of Thrombosis And Thrombolysis 2022, 54: 630-638. PMID: 35876942, DOI: 10.1007/s11239-022-02684-8.Peer-Reviewed Original ResearchConceptsOdds of in-hospital mortalityIn-Hospital MortalityAssociated with higher oddsPulmonary embolismNational Inpatient SamplePropensity score matchingEsophageal cancerLung cancerHigher oddsInpatient SamplePrognosis of PEScore matchingDiagnosis of PEClinically relevant covariatesPrimary diagnosis of PEMalignant groupOvarian cancerRetrospective studyMalignancyPrimary diagnosisRelevant covariatesCancerOddsPatientsMortalitySex-different interrelationships of rs945270, cerebral gray matter volumes, and attention deficit hyperactivity disorder: a region-wide study across brain
Luo X, Fang W, Lin X, Guo X, Chen Y, Tan Y, Wang L, Jing X, Wang X, Zhang Y, Yu T, Ide J, Cao Y, Yang L, Li CR. Sex-different interrelationships of rs945270, cerebral gray matter volumes, and attention deficit hyperactivity disorder: a region-wide study across brain. Translational Psychiatry 2022, 12: 225. PMID: 35654767, PMCID: PMC9163172, DOI: 10.1038/s41398-022-02007-8.Peer-Reviewed Original ResearchConceptsAttention deficit hyperactivity disorderADHD symptom scoresGray matter volumeDeficit hyperactivity disorderCortical gray matter volumePutamen gray matter volumesHyperactivity disorderADHD riskMatter volumePathogenesis of ADHDMediation effectBrain regionsLeft putamenCerebral gray matter volumeCerebral regionsRelevant covariatesAssociation of Prepregnancy Substance Use and Substance Use Disorders with Pregnancy Timing and Intention
Coy KC, Ko JY, Ondersma SJ, Gilstad-Hayden K, Zapata LB, Chang G, Yonkers K. Association of Prepregnancy Substance Use and Substance Use Disorders with Pregnancy Timing and Intention. Journal Of Women's Health 2022, 31: 1630-1638. PMID: 35352988, PMCID: PMC10970710, DOI: 10.1089/jwh.2021.0483.Peer-Reviewed Original ResearchConceptsSubstance use disordersSubstance usePregnancy timingUse disordersRobust error varianceConfidence intervalsPrenatal care sitesPostpartum carePregnancy intentionPrevalence ratiosIntended pregnanciesCare sitesPoisson regressionSecondary analysisIndependent relationshipPregnancyRelevant covariatesTotal sample sizeFamily planningWomenAssociationDisordersAssociations between average step counts, variability in step counts and nonhomeostatic eating
Kerrigan SG, Carr MM, Lawson JL, Lydecker JA, Grilo CM. Associations between average step counts, variability in step counts and nonhomeostatic eating. Eating And Weight Disorders - Studies On Anorexia, Bulimia And Obesity 2022, 27: 2165-2171. PMID: 35107825, PMCID: PMC9288421, DOI: 10.1007/s40519-022-01362-1.Peer-Reviewed Original ResearchConceptsReward-driven eatingNonhomeostatic eatingEmotional eatingIntraindividual variabilitySelf-report measuresGreater average levelsEatingCross-sectional correlation studyAverage levelLow intraindividual variabilityMethodsAdult participantsWeight outcomesComplex associationRelevant covariatesPA monitorParticipantsStep countAverage daily step countAssociationDaily stepsPhysical activity levelsOutcomesMeasuresActivity levelsHypothesisEvaluation of Firearm-related Reinjury in Connecticut: An Opportunity for Gun Violence Prevention
O'Neill KM, Jean RA, Dodington J, Davis K, Becher RD. Evaluation of Firearm-related Reinjury in Connecticut: An Opportunity for Gun Violence Prevention. Journal Of Surgical Research 2022, 274: 23-30. PMID: 35121547, DOI: 10.1016/j.jss.2021.12.009.Peer-Reviewed Original ResearchConceptsFirearm-related injuriesFirearm injuriesYale New Haven Health SystemMedical record dataChief Medical ExaminerCohort studyTrauma patientsGun violence preventionConnecticut OfficePatient controlsPatientsInjuryHealth systemRelevant covariatesPrevention effortsRecord dataViolence prevention effortsReinjuryMedical examinersMortalityFirearm violenceRiskViolence preventionHomicide mortalityYearsSocial determinants of health and obesity: Findings from a national study of US adults
Javed Z, Valero‐Elizondo J, Maqsood MH, Mahajan S, Taha MB, Patel KV, Sharma G, Hagan K, Blaha MJ, Blankstein R, Mossialos E, Virani SS, Cainzos‐Achirica M, Nasir K. Social determinants of health and obesity: Findings from a national study of US adults. Obesity 2022, 30: 491-502. PMID: 35088551, DOI: 10.1002/oby.23336.Peer-Reviewed Original ResearchConceptsOverweight/obesitySocial determinantsNon-Hispanic black adultsNational Health Interview SurveyObesity class 1Prevalence of overweightObesity class 3Odds of obesityHealth Interview SurveyHigher relative prevalenceCumulative social disadvantageLogistic regression modelsRace/ethnicityMultinomial logistic regression modelsObesity prevalenceHealth burdenUS adultsObesityObesity ratesBlack adultsOverweightRelevant covariatesInterview SurveyQuartilePrevalence
2021
Dehumanization of Older Family Members: Novel Determinants of Elder Abuse Proclivity by Caregivers
Chang E, Monin J, Zelterman D, Isenberg N, Levy B. Dehumanization of Older Family Members: Novel Determinants of Elder Abuse Proclivity by Caregivers. Innovation In Aging 2021, 5: 322-322. PMCID: PMC8680248, DOI: 10.1093/geroni/igab046.1250.Peer-Reviewed Original ResearchExplicit dehumanizationDenial of humannessFamily caregiversCaregiver burdenSelf-reported factorsCaregiver Abuse ScreenAge stereotypesAbuse perpetrationOlder personsPsychological factorsOlder family membersCare-recipient healthDehumanizationElder abuseAbuse ScreenCaregiversCurrent studyMost researchProclivityAbuseRelevant covariatesPersonsFamily membersPerpetrationHumannessThe impact of maternal adverse childhood experiences and prenatal depressive symptoms on foetal attachment: Preliminary evidence from expectant mothers across eight middle-income countries
Brown R, Eisner M, Walker S, Tomlinson M, Fearon P, Dunne M, Valdebenito S, Hughes C, Ward C, Sikander S, Osafo J, Madrid B, Baban A, Van Thang V, Fernando A, Murray A. The impact of maternal adverse childhood experiences and prenatal depressive symptoms on foetal attachment: Preliminary evidence from expectant mothers across eight middle-income countries. Journal Of Affective Disorders 2021, 295: 612-619. PMID: 34509077, DOI: 10.1016/j.jad.2021.08.066.Peer-Reviewed Original ResearchConceptsMaternal adverse childhood experiencesAdverse childhood experiencesPrenatal depressive symptomsMiddle-income countriesPrenatal depressionDepressive symptomsMaternal health careChildhood experiencesAntenatal careThird trimesterCohort evidenceACE exposureHigh-income countriesPostnatal periodExpectant mothersBaseline measurementsPostnatal attachmentSymptomsPath mediation analysisRelevant covariatesDepressionHealth careMothers' feelingsMothersPregnancy
2020
Protective effects of neighborhood community factors on elder abuse in India
Chang ES, Levy BR. Protective effects of neighborhood community factors on elder abuse in India. Journal Of Elder Abuse & Neglect 2020, 33: 1-16. PMID: 33375925, PMCID: PMC7904631, DOI: 10.1080/08946566.2020.1864695.Peer-Reviewed Original ResearchConceptsNeighborhood social cohesionElder abuseSocial cohesionOlder personsIndividual-level factorsHigh neighborhood social cohesionCommunity factorsProtective factorsGreater cohesionStructural factorsCohesionLongitudinal Aging StudyAbuseSignificant health benefitsRisk factorsIndiaProtective effectCountriesRelevant covariatesAging StudyHealth benefitsPolicyPhysical orderLow cohesionPersonsPositive Age Beliefs Lead to Lower Dementia Risk Even Among Older Persons With High-Risk Gene
Levy B, Slade M, Pietrzak R, Ferrucci L. Positive Age Beliefs Lead to Lower Dementia Risk Even Among Older Persons With High-Risk Gene. Innovation In Aging 2020, 4: 597-597. PMCID: PMC7742059, DOI: 10.1093/geroni/igaa057.2009.Peer-Reviewed Original ResearchOlder individualsLower dementia riskStrong risk factorRetirement Study participantsHigh-risk genesΕ4 variantDementia riskRisk factorsΕ4 carriersAPOE ε4High riskDementiaOlder personsStudy participantsAPOE geneProtective factorsRelevant covariatesRiskTotal sampleBaselineCurrent studyCohortΕ4IndividualsSystematic review of racial disparities in clozapine prescribing
Williams JC, Harowitz J, Glover J, Tek C, Srihari V. Systematic review of racial disparities in clozapine prescribing. Schizophrenia Research 2020, 224: 11-18. PMID: 33183948, DOI: 10.1016/j.schres.2020.07.023.Peer-Reviewed Original ResearchConceptsMinority patientsSystematic reviewRelevant covariatesRacial disparitiesUnderutilization of clozapineClinician-related factorsPatient-related factorsRacial minority patientsClozapine prescribingClozapine underutilizationHospital stayPrescription ratesAntipsychotic medicationIndependent reviewersEligibility criteriaElectronic databasesDisease severityRelevant studiesPrescribingPatientsInstitution-related factorsWhite counterpartsDirect examinationRacial groupsPossible causesWorse overall health status negatively impacts satisfaction with breast reconstruction
Mehta SK, Olawoyin O, Chouairi F, Duy PQ, Mets EJ, Gabrick KS, Le NK, Avraham T, Alperovich M. Worse overall health status negatively impacts satisfaction with breast reconstruction. Journal Of Plastic Reconstructive & Aesthetic Surgery 2020, 73: 2056-2062. PMID: 32972879, DOI: 10.1016/j.bjps.2020.08.093.Peer-Reviewed Original ResearchConceptsBREAST-Q scoresPatient-reported outcomesOverall health statusBreast reconstructionOverall healthASA classificationHealth statusGeneral linear modelAnesthesiologists physical status classificationYale-New Haven HospitalWorse overall health statusBREAST-Q outcomesHealth-related qualityPhysical status classificationNew Haven HospitalEffect of ASAASA 1Independent predictorsPatient factorsPostoperative satisfactionBreast surgeryPatient satisfactionASA 2PatientsRelevant covariatesTubulin Polymerization Promoting Protein (TPPP) gene methylation and corpus callosum measures in maltreated children
de Araújo CM, Hudziak J, Crocetti D, Wymbs NF, Montalvo-Ortiz JL, Orr C, Albaugh MD, Althoff RR, O'Loughlin K, Holbrook H, Garavan H, Yang BZ, Mostofsky S, Jackowski A, Lee RS, Gelernter J, Kaufman J. Tubulin Polymerization Promoting Protein (TPPP) gene methylation and corpus callosum measures in maltreated children. Psychiatry Research Neuroimaging 2020, 298: 111058. PMID: 32120304, PMCID: PMC11079625, DOI: 10.1016/j.pscychresns.2020.111058.Peer-Reviewed Original ResearchConceptsStress-related psychiatric disordersCorpus callosum measuresFractional anisotropyPsychiatric disordersTrauma experiencesWhite matter tractsChild trauma experiencesBrain changesLarger studyRelevant covariatesAtlas-based approachSplenium fractional anisotropyDNA specimensMultiple comparisonsGene methylationDisordersChildrenCurrent study
2019
Idealization of Youthfulness Predicts Worse Recovery Among Older Individuals
Levy BR, Slade MD, Lampert R. Idealization of Youthfulness Predicts Worse Recovery Among Older Individuals. Psychology And Aging 2019, 34: 202-207. PMID: 30730160, PMCID: PMC7397859, DOI: 10.1037/pag0000330.Peer-Reviewed Original ResearchImpact of Perceived Racism on Healthcare Access Among Older Minority Adults
Rhee TG, Marottoli RA, Van Ness PH, Levy BR. Impact of Perceived Racism on Healthcare Access Among Older Minority Adults. American Journal Of Preventive Medicine 2019, 56: 580-585. PMID: 30772147, PMCID: PMC6430677, DOI: 10.1016/j.amepre.2018.10.010.Peer-Reviewed Original ResearchConceptsAdequate health careForgone careDoctor communicationHealth careMultivariable logistic regression analysisCalifornia Health Interview SurveyHealth Interview SurveyLogistic regression analysisOlder minority adultsMinority older adultsStudy cohortSensitive communication skillsHealthcare accessHealth disparitiesOlder individualsRelevant covariatesOlder adultsInterview SurveyCareInsurance coverageMinority adultsRegression analysisMinority individualsWhite counterpartsAdults
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