2022
In-hospital prognosis of malignancy-related pulmonary embolism: an analysis of the national inpatient sample 2016–2018
Park D, An S, Kashoor I, Ezegwu O, Gupta S. In-hospital prognosis of malignancy-related pulmonary embolism: an analysis of the national inpatient sample 2016–2018. Journal Of Thrombosis And Thrombolysis 2022, 54: 630-638. PMID: 35876942, DOI: 10.1007/s11239-022-02684-8.Peer-Reviewed Original ResearchConceptsOdds of in-hospital mortalityIn-Hospital MortalityAssociated with higher oddsPulmonary embolismNational Inpatient SamplePropensity score matchingEsophageal cancerLung cancerHigher oddsInpatient SamplePrognosis of PEScore matchingDiagnosis of PEClinically relevant covariatesPrimary diagnosis of PEMalignant groupOvarian cancerRetrospective studyMalignancyPrimary diagnosisRelevant covariatesCancerOddsPatientsMortality
2019
Increased Sensitivity of Focused Cardiac Ultrasound for Pulmonary Embolism in Emergency Department Patients With Abnormal Vital Signs
Daley JI, Dwyer KH, Grunwald Z, Shaw DL, Stone MB, Schick A, Vrablik M, Hall M, Hall J, Liteplo AS, Haney RM, Hun N, Liu R, Moore CL. Increased Sensitivity of Focused Cardiac Ultrasound for Pulmonary Embolism in Emergency Department Patients With Abnormal Vital Signs. Academic Emergency Medicine 2019, 26: 1211-1220. PMID: 31562679, DOI: 10.1111/acem.13774.Peer-Reviewed Original ResearchConceptsAbnormal vital signsComputed tomography angiographyBeats/minPulmonary embolismVital signsProspective observational multicenter cohort studyCardiac ultrasoundTricuspid annular plane systolic excursionObservational multicenter cohort studyAnnular plane systolic excursionDiagnosis of PERight ventricular dysfunctionMulticenter cohort studyRight ventricular dilationUrban academic EDEmergency department patientsEntire patient populationVital sign abnormalitiesFocused cardiac ultrasoundRapid bedside testDiagnostic test characteristicsSubstantial interobserver agreementMcConnell's signVentricular dysfunctionCohort study
2016
Emergency physician performed tricuspid annular plane systolic excursion in the evaluation of suspected pulmonary embolism
Daley J, Grotberg J, Pare J, Medoro A, Liu R, Hall MK, Taylor A, Moore CL. Emergency physician performed tricuspid annular plane systolic excursion in the evaluation of suspected pulmonary embolism. The American Journal Of Emergency Medicine 2016, 35: 106-111. PMID: 27793505, DOI: 10.1016/j.ajem.2016.10.018.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedAged, 80 and overCohort StudiesComputed Tomography AngiographyEchocardiographyEmergency MedicineFemaleHumansMaleMiddle AgedObserver VariationPhysiciansPoint-of-Care SystemsPoint-of-Care TestingProspective StudiesPulmonary EmbolismReproducibility of ResultsROC CurveSensitivity and SpecificitySystoleTricuspid ValveVentricular Dysfunction, RightYoung AdultConceptsTricuspid annular plane systolic excursionAnnular plane systolic excursionDiagnosis of PEPulmonary embolismSystolic excursionProspective observational cohort studyUrban academic emergency departmentObservational cohort studyAcademic emergency departmentCharacteristic curve analysisModerate diagnostic valueIntraclass correlation coefficientCohort studyEmergency departmentTomographic angiographyEmergency physiciansOptimal cutoffPatientsDiagnostic valueAbnormal cutoffsSecondary objectiveΚ statisticCurve analysisConvenience sampleInterrater reliability
2015
Role of D-dimer Assays in the Diagnostic Evaluation of Pulmonary Embolism
Jain S, Khera R, Suneja M, Gehlbach B, Kuperman E, Lopez F. Role of D-dimer Assays in the Diagnostic Evaluation of Pulmonary Embolism. The American Journal Of The Medical Sciences 2015, 350: 501-507. PMID: 25719981, DOI: 10.1097/maj.0000000000000405.Peer-Reviewed Case Reports and Technical NotesConceptsDiagnosis of PEPulmonary embolismClinical featuresD-dimerDiagnostic algorithmPositive D-dimer testNonspecific clinical featuresSimple noninvasive testD-dimer testD-dimer assayClinician suspicionInitial imagingAlternative diagnosesElderly menNoninvasive testsClinical algorithmDiagnostic evaluationChest imagingDiagnosisEmbolismLittle valueImagingComorbiditiesPneumoniaPatients
2012
ACR Appropriateness Criteria® Acute Chest Pain—Suspected Pulmonary Embolism
Bettmann M, Baginski S, White R, Woodard P, Abbara S, Atalay M, Dorbala S, Haramati L, Hendel R, Martin E, Ryan T, Steiner R. ACR Appropriateness Criteria® Acute Chest Pain—Suspected Pulmonary Embolism. Journal Of Thoracic Imaging 2012, 27: w28-w31. PMID: 22343403, DOI: 10.1097/rti.0b013e31823efeb6.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsConceptsPulmonary embolismAppropriateness CriteriaClinical conditionsDiagnosis of PEDiagnostic imagingAppropriateness of imagingAcute chest painACR Appropriateness CriteriaDeep vein thrombosisTomography pulmonary angiographyLower extremity ultrasoundMultidisciplinary expert panelRadiology Appropriateness CriteriaEvidence-based guidelinesD-dimer testSpecific clinical conditionsHigh pretest probabilityCurrent medical literatureImportant clinical conditionBasis of signsMajor diagnostic modalityChest painPeer-reviewed journalsVein thrombosisClinical status
2011
Diagnosis and Management of Life-Threatening Pulmonary Embolism
Marshall PS, Mathews KS, Siegel MD. Diagnosis and Management of Life-Threatening Pulmonary Embolism. Journal Of Intensive Care Medicine 2011, 26: 275-294. PMID: 21606060, DOI: 10.1177/0885066610392658.Peer-Reviewed Original ResearchConceptsMassive pulmonary embolusDiagnosis of PECatheter-based therapiesPulmonary emboliTomographic pulmonary angiographySurgical embolectomyThrombolytic therapyPoor outcomePulmonary angiographyLife-threatening pulmonary emboliLife-Threatening Pulmonary EmbolismLower extremity Doppler ultrasoundInferior vena cava filterComplicated hospital courseImproved pulmonary perfusionPulmonary artery vasodilatorsRecurrent pulmonary emboliRight ventricular dysfunctionUse of vasopressorsBrain natriuretic peptidePresence of hypotensionLife-threatening hemorrhageChoice of treatmentCatheter-based interventionsVena cava filters
2010
The role of urinary soluble endoglin in the diagnosis of pre‐eclampsia: comparison with soluble fms‐like tyrosine kinase 1 to placental growth factor ratio
Buhimschi C, Baumbusch M, Dulay A, Lee S, Wehrum M, Zhao G, Bahtiyar M, Pettker C, Ali U, Funai E, Buhimschi I. The role of urinary soluble endoglin in the diagnosis of pre‐eclampsia: comparison with soluble fms‐like tyrosine kinase 1 to placental growth factor ratio. BJOG An International Journal Of Obstetrics & Gynaecology 2010, 117: 321-330. PMID: 19943826, DOI: 10.1111/j.1471-0528.2009.02434.x.Peer-Reviewed Original ResearchMeSH KeywordsAdultAntigens, CDBiomarkersChronic DiseaseDiagnosis, DifferentialEndoglinFemaleGrowth HormoneHumansHypertensionPlacental HormonesPre-EclampsiaPregnancyPregnancy Complications, CardiovascularProspective StudiesReceptors, Cell SurfaceSensitivity and SpecificityVascular Endothelial Growth Factor Receptor-1Young AdultConceptsSoluble fms-like tyrosine kinase-1Fms-like tyrosine kinase-1Tyrosine kinase-1Placental growth factor ratioGrowth factor ratioSoluble endoglinDiagnosis of PEGestational agePlGF ratioChronic hypertensionHealthy controlsPreterm PEUrinary levelsSevere PEMild PEWeeks of GATertiary referral university hospitalKinase 1Prospective observational cohortSoluble endoglin levelsReferral university hospitalWeeks of gestationIdentification of womenSeverity of PEUrine of women
2007
Increased diagnosis of pulmonary embolism without a corresponding decline in mortality during the CT era
Burge A, Freeman K, Klapper P, Haramati L. Increased diagnosis of pulmonary embolism without a corresponding decline in mortality during the CT era. Clinical Radiology 2007, 63: 381-386. PMID: 18325357, DOI: 10.1016/j.crad.2007.10.004.Peer-Reviewed Original ResearchConceptsDiagnosis of PEPulmonary embolismPE diagnosisRisk factorsMultivariate analysisAge-adjusted multivariate analysisResearch Cooperative System databaseComputed tomography (CT) useNumber of patientsUse of CTCorresponding risk factorsPE deathsTotal admissionsPrimary diagnosisTomography useCT eraCT useIndividual patientsStudy populationPatientsSignificant associationMortalityNew York StateDiagnosisStudy period
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