2025
Expected Surgical Risk and the Risk of Stroke and Brain Injury After Transcatheter Aortic Valve Replacement: A Patient-Level Pooled Analysis
Messé S, Grubman D, Huerter M, Dwyer M, Zivadinov R, Pietras C, Nazif T, Moses J, Shah T, Gambone L, Tripathi R, Forrest J, Vora A, Parise H, Lansky A. Expected Surgical Risk and the Risk of Stroke and Brain Injury After Transcatheter Aortic Valve Replacement: A Patient-Level Pooled Analysis. Journal Of The Society For Cardiovascular Angiography & Interventions 2025, 4: 103867. DOI: 10.1016/j.jscai.2025.103867.Peer-Reviewed Original ResearchTranscatheter aortic valve replacementAortic valve replacementHigh-risk patientsDW-MRIPooled analysisAcute brain injuryDW-MRI measurementsSTS-PROMValve replacementRisk patientsClinical outcomesLesion volumePatient-level pooled analysisCognitive declineMyocardial infarctionTransfemoral transcatheter aortic valve replacementClinical events committeeDiffusion-weighted magnetic resonance imagingSurgical mortality riskRisk-stratify patientsBrain injuryRates of all-causeAcute kidney injuryTotal lesion volumeRisk of strokeThe Impact of Aortic Arch Morphology on Periprocedural Stroke in Transcatheter Aortic Valve Replacement
Voss S, Rusa K, Campanella C, Georgescu T, Vitanova K, Ruge H, Amabile A, Sideris K, Krane M, Burri M. The Impact of Aortic Arch Morphology on Periprocedural Stroke in Transcatheter Aortic Valve Replacement. Journal Of Clinical Medicine 2025, 14: 1045. PMID: 40004577, PMCID: PMC11856225, DOI: 10.3390/jcm14041045.Peer-Reviewed Original ResearchTranscatheter aortic valve replacementMulti-Slice Computed TomographyAortic valve replacementAortic arch morphologyArch anatomyValve replacementPeriprocedural strokeLeft common carotid arteryTransfemoral transcatheter aortic valve replacementEpi-aortic vesselsIschemic strokeArch morphologyPeriprocedural ischemic strokePropensity-matched case-control studyScore-matched studyCase-control studyCommon carotid arteryOccurrence of ischemic strokeAortic arch geometryEuroSCORE IIPropensity score matchingAortic archComparing PatientsCatheter manipulationCarotid artery
2024
Cerebral embolic protection device utilization and outcomes in transcatheter aortic valve replacement: A nationally representative propensity matched analysis
Altibi A, Alhuneafat L, Jabri A, Al-Abdouh A, Ghanem F. Cerebral embolic protection device utilization and outcomes in transcatheter aortic valve replacement: A nationally representative propensity matched analysis. Cardiovascular Revascularization Medicine 2024, 67: 112-114. PMID: 38653674, DOI: 10.1016/j.carrev.2024.04.003.Peer-Reviewed Original ResearchTranscatheter aortic valve replacementCerebral embolic protection devicesAortic valve replacementPropensity score matchingNational Readmission DatabaseIn-Hospital StrokeValve replacementIn-HospitalPeriprocedural strokeOdds ratioTranscatheter aortic valve replacement patientsTransfemoral transcatheter aortic valve replacementPropensity score matched cohortAssociated with decreased riskScore matchingPropensity matched analysisRisk of periprocedural strokeRisk of in-hospital strokeAcute kidney injuryTAVR admissionsIn-Hospital MortalityConfidence intervalsOutcomes post-TAVRAssociated with reduced oddsEmbolic protection devices
2023
Cerebral embolic protection during transcatheter heart interventions.
Jimenez Diaz V, Kapadia S, Linke A, Mylotte D, Lansky A, Grube E, Settergren M, Puri R. Cerebral embolic protection during transcatheter heart interventions. EuroIntervention 2023, 19: 549-570. PMID: 37720969, PMCID: PMC10495748, DOI: 10.4244/eij-d-23-00166.Peer-Reviewed Original ResearchConceptsCerebral embolic protection devicesTranscatheter aortic valve replacementNew cerebral lesionsMajority of patientsCerebral lesionsTransfemoral transcatheter aortic valve replacementHeart interventionsCerebral embolic protectionAortic valve replacementEmbolic protection devicesBrain imaging studiesPrimary endpointDevastating complicationPeriprocedural strokeValve replacementEmbolic protectionEmbolic showerApparent strokeCerebral embolisationTranscatheter proceduresSpecific trialsImaging studiesStrokePatientsLesions
2022
Hospital procedural volume and clinical outcomes for transcatheter aortic valve replacement – US nationwide readmission database, 2016–2019
Altibi A, Ghanem F, Patel J, Al-Taweel O, Chadderdon S, Song H, Lantz G, Zahr F, Golwala H. Hospital procedural volume and clinical outcomes for transcatheter aortic valve replacement – US nationwide readmission database, 2016–2019. European Heart Journal 2022, 43: ehac544.2097. DOI: 10.1093/eurheartj/ehac544.2097.Peer-Reviewed Original ResearchTranscatheter aortic valve replacementHigh-volume centersTransfemoral transcatheter aortic valve replacementNational Readmission DatabaseUS Nationwide Readmission DatabaseClinical outcomesHigh-volume hospitalsHospital procedure volumeProcedure volumePost-TAVRTAVR proceduresReadmission ratesReadmissions DatabaseHospital volumeTranscatheter Aortic Valve Replacement OutcomesCompare overall outcomesMultivariate logistic regression analysisHigh-volume TAVR centersDays post-TAVRTranscatheter aortic valve replacement casesAdverse in-hospital eventsAortic valve replacementHospital length of stayIn-hospital cardiac arrestAcute kidney injuryPeripheral access size evaluation in transfemoral transcatheter aortic valve replacement
Hameed I, Oakley CT, Hameed NUF, Jiang Y, Naeem N, Morsi M, Ahmed A, Amabile A, Hirji S, Truong QA, Gaudino M, Kaneko T, Salemi A. Peripheral access size evaluation in transfemoral transcatheter aortic valve replacement. Journal Of Cardiac Surgery 2022, 37: 801-807. PMID: 35137971, DOI: 10.1111/jocs.16293.Peer-Reviewed Original ResearchConceptsTranscatheter aortic valve replacementMinimal luminal diameterBody mass indexAortic valve replacementPeripheral vascular diseaseAccess vessel sizeFemoral arteryValve replacementInguinal ligamentVascular diseaseOutcomes of TAVRTransfemoral transcatheter aortic valve replacementPatient's individual risk factorsMean body mass indexContrast-enhanced CTATomography Angiography AssessmentSymptomatic aortic stenosisChronic kidney diseaseCommon iliac arteryCoronary artery diseaseHigh-volume centersDeep femoral arteryTranscatheter heart valveGeneral patient populationIndividual risk factors
2020
Incidence, Temporal Trends, and Associated Outcomes of Vascular and Bleeding Complications in Patients Undergoing Transfemoral Transcatheter Aortic Valve Replacement
Sherwood M, Xiang K, Matsouaka R, Li Z, Vemulapalli S, Vora A, Fanaroff A, Harrison J, Thourani V, Holmes D, Kirtane A, Pineda A, Peterson E, Rao S. Incidence, Temporal Trends, and Associated Outcomes of Vascular and Bleeding Complications in Patients Undergoing Transfemoral Transcatheter Aortic Valve Replacement. Circulation Cardiovascular Interventions 2020, 13: e008227. PMID: 31937138, DOI: 10.1161/circinterventions.119.008227.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overCatheterization, PeripheralFemaleFemoral ArteryHospital MortalityHumansIncidenceMalePatient ReadmissionPostoperative HemorrhageRegistriesRisk AssessmentRisk FactorsStrokeTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesVascular DiseasesConceptsTranscatheter aortic valve replacementAortic valve replacementIn-hospital bleeding eventsBleeding eventsValve replacementAssociated with 30-day deathVascular complicationsBleeding complicationsClinical outcomesComplication rateTranscatheter aortic valve replacement clinical trialsSociety of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy RegistryAssociated with worse short-Long-term clinical outcomesIn-hospital clinical outcomesTransfemoral transcatheter aortic valve replacementTranscatheter Valve Therapy RegistryIn-hospital vascular complicationsUS clinical practiceAll-Cause MortalityMultivariate logistic regressionAntithrombotic therapyEvaluating patientsVascular/bleeding complicationsDetrimental complications
2018
Variation in post-TAVR antiplatelet therapy utilization and associated outcomes: Insights from the STS/ACC TVT Registry
Sherwood M, Vemulapalli S, Harrison J, Dai D, Vora A, Mack M, Holmes D, Rumsfeld J, Cohen D, Thourani V, Kirtane A, Peterson E. Variation in post-TAVR antiplatelet therapy utilization and associated outcomes: Insights from the STS/ACC TVT Registry. American Heart Journal 2018, 204: 9-16. PMID: 30075326, DOI: 10.1016/j.ahj.2018.06.006.Peer-Reviewed Original ResearchMeSH KeywordsCause of DeathDrug Therapy, CombinationFibrinolytic AgentsHemorrhageHumansMyocardial InfarctionPlatelet Aggregation InhibitorsPostoperative CarePostoperative ComplicationsPractice Patterns, Physicians'Risk FactorsStrokeThrombosisTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsTranscatheter aortic valve replacementDual antiplatelet therapyPractice patternsAntiplatelet therapyMyocardial infarctionNational Cardiovascular Data RegistryPost-TAVRArtery diseaseSociety of Thoracic Surgeons/American College of Cardiology Transcatheter Valve Therapy RegistryTransfemoral transcatheter aortic valve replacementTranscatheter Valve Therapy RegistryRates of coronary artery diseaseRisk of mortalityOptimal antiplatelet strategyAortic valve replacementDual antiplatelet therapy useOptimal antiplatelet therapyContemporary practice patternsPeripheral arterial diseaseCoronary artery diseaseOutcomes post-TAVRSTS/ACC TVT RegistryService linkagesTherapy utilizationMortality risk
2017
Conscious Sedation Versus General Anesthesia for Transcatheter Aortic Valve Replacement
Hyman MC, Vemulapalli S, Szeto WY, Stebbins A, Patel PA, Matsouaka RA, Herrmann HC, Anwaruddin S, Kobayashi T, Desai ND, Vallabhajosyula P, McCarthy FH, Li R, Bavaria JE, Giri J. Conscious Sedation Versus General Anesthesia for Transcatheter Aortic Valve Replacement. Circulation 2017, 136: 2132-2140. PMID: 28864443, DOI: 10.1161/circulationaha.116.026656.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAnesthesia, GeneralAortic Valve StenosisComparative Effectiveness ResearchConscious SedationFemaleHospital MortalityHumansIntention to Treat AnalysisLength of StayMalePatient DischargePractice Patterns, Physicians'RegistriesRisk AssessmentRisk FactorsTime FactorsTranscatheter Aortic Valve ReplacementTreatment OutcomeUnited StatesConceptsTranscatheter aortic valve replacementAortic valve replacementConscious sedationIntensive care unitGeneral anesthesiaHospital lengthValve replacementProcedural successCare unitEnd-point analysisPercutaneous transfemoral transcatheter aortic valve replacementConscious Sedation Versus General AnesthesiaTransfemoral transcatheter aortic valve replacementCardiology Transcatheter Valve Therapy RegistryThoracic Surgeons/American CollegeDeath/stroke ratePacemaker/defibrillator implantationTranscatheter Valve Therapy RegistryInverse probabilityConscious sedation groupDeath/strokeTreatment-weighted adjustmentTreatment-weighted analysisLower procedural successComparative effectiveness analysis
2015
A balloon-expandable sheath facilitates transfemoral TAVR in patients with peripheral vascular disease and tortuosity
Goldsweig AM, Faheem O, Cleman MW, Forrest JK. A balloon-expandable sheath facilitates transfemoral TAVR in patients with peripheral vascular disease and tortuosity. Therapeutic Advances In Cardiovascular Disease 2015, 9: 95-102. PMID: 25784499, DOI: 10.1177/1753944715575970.Peer-Reviewed Original ResearchConceptsTransfemoral transcatheter aortic valve replacementTranscatheter aortic valve replacementPeripheral arterial diseaseSurgical aortic valve replacementBalloon-expandable sheathAortic valve replacementVascular tortuosityValve replacementTransfemoral approachSuccessful transcatheter aortic valve replacementVascular access complicationsPeripheral vascular diseaseTerms of mortalityPostprocedural angiographyTAVR resultsAccess complicationsSurgical cutdownSurgical riskArterial diseaseSevere stenosisVascular accessTransapical accessVascular diseaseMortality riskPatients
2014
Factors Associated With Vascular Complications in Patients Undergoing Balloon-Expandable Transfemoral Transcatheter Aortic Valve Replacement via Open Versus Percutaneous Approaches
Kadakia MB, Herrmann HC, Desai ND, Fox Z, Ogbara J, Anwaruddin S, Jagasia D, Bavaria JE, Szeto WY, Vallabhajosyula P, Li R, Menon R, Kobrin DM, Giri J. Factors Associated With Vascular Complications in Patients Undergoing Balloon-Expandable Transfemoral Transcatheter Aortic Valve Replacement via Open Versus Percutaneous Approaches. Circulation Cardiovascular Interventions 2014, 7: 570-576. PMID: 25027520, DOI: 10.1161/circinterventions.113.001030.Peer-Reviewed Original ResearchConceptsTransfemoral transcatheter aortic valve replacementTranscatheter aortic valve replacementAortic valve replacementVascular complicationsLength of stayValve replacementOpen surgicalPC groupMultivariable analysisArtery diameterValve Academic Research ConsortiumSheath outer diameterMajor vascular complicationsAcademic Research ConsortiumPropensity-matched analysisPostprocedural lengthPropensity matchingClinical outcomesSignificant morbidityFemale sexPercutaneous approachSimilar riskComplicationsOS groupStay
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