Dae Yup Han, PhD, DABR
Assistant Professor of Therapeutic RadiologyCards
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Featured Publications
Direction-Modulated Brachytherapy for High-Dose-Rate Treatment of Cervical Cancer. I: Theoretical Design
Han D, Webster M, Scanderbeg D, Yashar C, Choi D, Song B, Devic S, Ravi A, Song W. Direction-Modulated Brachytherapy for High-Dose-Rate Treatment of Cervical Cancer. I: Theoretical Design. International Journal Of Radiation Oncology • Biology • Physics 2014, 89: 666-673. PMID: 24751413, DOI: 10.1016/j.ijrobp.2014.02.039.Peer-Reviewed Original ResearchMeSH KeywordsAdultAlgorithmsBrachytherapyColon, SigmoidEquipment DesignFemaleHumansIridium RadioisotopesMagnetic Resonance ImagingMiddle AgedMonte Carlo MethodOrgans at RiskRadiation InjuriesRadiotherapy DosageRadiotherapy Planning, Computer-AssistedRectumTungstenUrinary BladderUterine Cervical NeoplasmsYoung AdultConceptsCervical cancerHigh-risk clinical target volume D90Sizeable patient populationSimilar target coveragePlan qualityTreatment plan qualityPatient populationPrescription doseHigh doseRate brachytherapyImproved organClinical validationAnatomic informationPatient casesTarget coverageCancerBrachytherapyOvoid applicatorsPeripheral holesDose distributionDwell positionsBladderD2ccRectumDoseDirection Modulated Brachytherapy for Treatment of Cervical Cancer. II: Comparative Planning Study With Intracavitary and Intracavitary–Interstitial Techniques
Han DY, Safigholi H, Soliman A, Ravi A, Leung E, Scanderbeg DJ, Liu Z, Owrangi A, Song WY. Direction Modulated Brachytherapy for Treatment of Cervical Cancer. II: Comparative Planning Study With Intracavitary and Intracavitary–Interstitial Techniques. International Journal Of Radiation Oncology • Biology • Physics 2016, 96: 440-448. PMID: 27598809, DOI: 10.1016/j.ijrobp.2016.06.015.Peer-Reviewed Original ResearchConceptsComparative planning studyCervical cancerGroupe Européen de Curiethérapie-European SocietyOriginal clinical plansCervical cancer patientsTandem applicatorUse of needlesOncology recommendationsCancer patientsAdaptive brachytherapyClinical practiceClinical plansPotential clinical translationPlan qualityPatientsCancerClinical translationBrachytherapyNeedle applicatorConsistent improvementD90 valuesStandard tandemPlanning studiesStandard applicatorsTotal numberTreatment Delivery Technology for Brachytherapy
Cunha J, Han D. Treatment Delivery Technology for Brachytherapy. 2017, 41-67. DOI: 10.1007/978-3-319-44827-5_3.ChaptersResection Cavity Contraction Effects in the Use of Radioactive Sources (1-25 versus Cs-131) for Intra-Operative Brain Implants
Han D, Ma L, Braunstein S, Raleigh D, Sneed P, McDermott M, McDermott M. Resection Cavity Contraction Effects in the Use of Radioactive Sources (1-25 versus Cs-131) for Intra-Operative Brain Implants. Cureus 2018, 10: e2079. PMID: 29560292, PMCID: PMC5856410, DOI: 10.7759/cureus.2079.Peer-Reviewed Original ResearchResection cavityConsecutive patient casesResection cavity volumeSurgical resection cavityBiological effective dose (BED) calculationRate brachytherapy implantsBrain implantsDose distributionAccumulative dosesImplant procedureDose variabilityMagnetic resonance imagesEffective dose calculationPatient casesD10 valuesCs-131Significant differencesBrachytherapy implantsResonance imagesContractionMonthsImplantsBED calculationsD90Static volume
2023
Dosimetric response of Gafchromic™ EBT‐XD film to therapeutic protons
Guan F, Wang X, Yang M, Draeger E, Han D, Iga K, Guo F, Perles L, Li Y, Sahoo N, Mohan R, Chen Z. Dosimetric response of Gafchromic™ EBT‐XD film to therapeutic protons. Precision Radiation Oncology 2023, 7: 15-26. PMID: 37868341, PMCID: PMC10586355, DOI: 10.1002/pro6.1187.Peer-Reviewed Original ResearchLinear energy transferEBT-XD filmsTherapeutic protonsFilm calibrationProton linear energy transferUltra-high Dose Rate FLASH RadiotherapyDynamic dose rangeMV photon beamDose-averaged LET valuesDose rate dependenceProton beamlineProton beamPhoton beamsFLASH beamSpot scanning proton beamsDosimetric responseLET dependenceFLASH radiotherapyHigh-dose applicationFilm responseLET valuesEnergy transferBeamProtonsGafchromic
2022
Frequency of errors in the transfer of treatment parameters from the treatment planning system to the oncology information system in a multi‐vendor environment
Donahue W, Draeger E, Han D, Chen Z. Frequency of errors in the transfer of treatment parameters from the treatment planning system to the oncology information system in a multi‐vendor environment. Journal Of Applied Clinical Medical Physics 2022, 24: e13868. PMID: 36527239, PMCID: PMC10113690, DOI: 10.1002/acm2.13868.Peer-Reviewed Original ResearchConceptsInformation systemsTransfer of dataPlanning systemSoftware systemsOncology information systemMultiple vendorsData transferField labelsData inputTimer settingsNumber of errorsTechnological advancementsErrorSystemVendorsAdvancementTreatment planning systemFrequency of errorsMOSAIQCommon errorsLabelsInformation
2019
Dynamic Modulated Brachytherapy (DMBT) Balloon Applicator for Accelerated Partial Breast Irradiation
Guy C, Oh S, Han D, Kim S, Arthur D, Song W. Dynamic Modulated Brachytherapy (DMBT) Balloon Applicator for Accelerated Partial Breast Irradiation. International Journal Of Radiation Oncology • Biology • Physics 2019, 104: 953-961. PMID: 30910767, DOI: 10.1016/j.ijrobp.2019.03.026.Peer-Reviewed Original ResearchConceptsPartial breast irradiationTreatment planBreast irradiationTarget coverageEarly-stage breast cancerAccelerated Partial Breast IrradiationInstitutional review board approvalCurrent treatment planSimilar target coverageReview board approvalNew treatment planDose regimensClinical treatment plansBreast cancerMean reductionBalloon deviceBoard approvalBalloon volumeDosimetric advantagesBalloon applicatorDosimetric changesClinical plansBalloon surfaceTreatment deliveryPatientsOptimizing beam models for dosimetric accuracy over a wide range of treatments
Chen J, Morin O, Weethee B, Perez-Andujar A, Phillips J, Held M, Kearny V, Han D, Cheung J, Chuang C, Valdes G, Sudhyadhom A, Solberg T. Optimizing beam models for dosimetric accuracy over a wide range of treatments. Physica Medica 2019, 58: 47-53. PMID: 30824149, DOI: 10.1016/j.ejmp.2019.01.011.Peer-Reviewed Original Research
2018
Direction modulated brachytherapy (DMBT) tandem applicator for cervical cancer treatment: Choosing the optimal shielding material
Safigholi H, Han DY, Soliman A, Song WY. Direction modulated brachytherapy (DMBT) tandem applicator for cervical cancer treatment: Choosing the optimal shielding material. Medical Physics 2018, 45: 3524-3533. PMID: 29858499, DOI: 10.1002/mp.13030.Peer-Reviewed Original Research
2017
Quantitative CT assessment of a novel direction-modulated brachytherapy tandem applicator
Elzibak AH, Kager PM, Soliman A, Paudel MR, Safigholi H, Han DY, Karotki A, Ravi A, Song WY. Quantitative CT assessment of a novel direction-modulated brachytherapy tandem applicator. Brachytherapy 2017, 17: 465-475. PMID: 29174936, DOI: 10.1016/j.brachy.2017.10.006.Peer-Reviewed Original Research
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