Liping Zhao, MS, HT (ASCP)
Clinical Technologist 3DownloadHi-Res Photo
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Clinical Technologist 3
Education & Training
- Histological Technician
- Harford Community College (2014)
- MS
- University of Bridgeport, Computer Science (2002)
- MS
- Harbin Institute of Technology, Mechanical Engineering (1989)
Research
Research at a Glance
Yale Co-Authors
Frequent collaborators of Liping Zhao's published research.
Publications Timeline
A big-picture view of Liping Zhao's research output by year.
Laura Niklason, PhD, MD
Erica Herzog, MD, PhD
Yibing Qyang, PhD
Allison M. Greaney, PhD
Jason Thomson
Jiasheng Zhang, MD
17Publications
1,873Citations
Publications
2020
Glycocalyx‐Like Hydrogel Coatings for Small Diameter Vascular Grafts
Dimitrievska S, Wang J, Lin T, Weyers A, Bai H, Qin L, Li G, Cai C, Kypson A, Kristofik N, Gard A, Sundaram S, Yamamoto K, Wu W, Zhao L, Kural M, Yuan Y, Madri J, Kyriakides T, Linhardt R, Niklason L. Glycocalyx‐Like Hydrogel Coatings for Small Diameter Vascular Grafts. Advanced Functional Materials 2020, 30 DOI: 10.1002/adfm.201908963.Peer-Reviewed Original ResearchCitationsTissue-Engineered Vascular Grafts with Advanced Mechanical Strength from Human iPSCs
Luo J, Qin L, Zhao L, Gui L, Ellis MW, Huang Y, Kural MH, Clark JA, Ono S, Wang J, Yuan Y, Zhang SM, Cong X, Li G, Riaz M, Lopez C, Hotta A, Campbell S, Tellides G, Dardik A, Niklason LE, Qyang Y. Tissue-Engineered Vascular Grafts with Advanced Mechanical Strength from Human iPSCs. Cell Stem Cell 2020, 26: 251-261.e8. PMID: 31956039, PMCID: PMC7021512, DOI: 10.1016/j.stem.2019.12.012.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and Concepts
2016
Engineered Tissue–Stent Biocomposites as Tracheal Replacements
Zhao L, Sundaram S, Le AV, Huang AH, Zhang J, Hatachi G, Beloiartsev A, Caty MG, Yi T, Leiby K, Gard A, Kural MH, Gui L, Rocco KA, Sivarapatna A, Calle E, Greaney A, Urbani L, Maghsoudlou P, Burns A, DeCoppi P, Niklason LE. Engineered Tissue–Stent Biocomposites as Tracheal Replacements. Tissue Engineering Part A 2016, 22: 1086-1097. PMID: 27520928, PMCID: PMC5312617, DOI: 10.1089/ten.tea.2016.0132.Peer-Reviewed Original ResearchCitationsAltmetricComparative biology of decellularized lung matrix: Implications of species mismatch in regenerative medicine
Balestrini JL, Gard AL, Gerhold KA, Wilcox EC, Liu A, Schwan J, Le AV, Baevova P, Dimitrievska S, Zhao L, Sundaram S, Sun H, Rittié L, Dyal R, Broekelmann TJ, Mecham RP, Schwartz MA, Niklason LE, White ES. Comparative biology of decellularized lung matrix: Implications of species mismatch in regenerative medicine. Biomaterials 2016, 102: 220-230. PMID: 27344365, PMCID: PMC4939101, DOI: 10.1016/j.biomaterials.2016.06.025.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsHuman endothelial cellsCell-matrix interactionsLung regenerationEndothelial cellsKey matrix proteinsComparative biologyCell adhesion moleculeMatrix proteinsLung extracellular matrixCell healthExtracellular matrixResidual DNASpecies mismatchRat lung scaffoldsRegenerative medicineAdhesion moleculesLung scaffoldsPrimate tissuesCellsVascular cell adhesion moleculeLung engineeringLung matrixLess expressionPulmonary cellsProfound effectImplantable tissue-engineered blood vessels from human induced pluripotent stem cells
Gui L, Dash BC, Luo J, Qin L, Zhao L, Yamamoto K, Hashimoto T, Wu H, Dardik A, Tellides G, Niklason LE, Qyang Y. Implantable tissue-engineered blood vessels from human induced pluripotent stem cells. Biomaterials 2016, 102: 120-129. PMID: 27336184, PMCID: PMC4939127, DOI: 10.1016/j.biomaterials.2016.06.010.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsVascular smooth muscle cellsVascular diseaseBlood vesselsAlpha-smooth muscle actinSmooth muscle myosin heavy chainActive vascular remodelingSmooth muscle cellsMuscle myosin heavy chainTissue-engineered blood vesselsStem cellsAbundant collagenous matrixPluripotent stem cellsInterposition graftAllogeneic graftsVascular remodelingΑ-SMANude ratsMuscle actinMyosin heavy chainClinical useMuscle cellsFunctional vascular smooth muscle cellsPatientsFunctional tissue-engineered blood vesselGraftBiaxial Stretch Improves Elastic Fiber Maturation, Collagen Arrangement, and Mechanical Properties in Engineered Arteries
Huang AH, Balestrini JL, Udelsman BV, Zhou KC, Zhao L, Ferruzzi J, Starcher BC, Levene MJ, Humphrey JD, Niklason LE. Biaxial Stretch Improves Elastic Fiber Maturation, Collagen Arrangement, and Mechanical Properties in Engineered Arteries. Tissue Engineering Part C Methods 2016, 22: 524-533. PMID: 27108525, PMCID: PMC4921901, DOI: 10.1089/ten.tec.2015.0309.Peer-Reviewed Original ResearchCitationsMeSH Keywords and ConceptsConceptsTissue-engineered blood vesselsBiaxial loadingMechanical propertiesMechanical strengthFiber orientationMultiaxial loadingLoading conditionsMechanical integrityBiaxial stretchingCollagen undulationArtificial skinNovel bioreactorMechanical failureMatrix orientationBiaxial stretchLoadingAxial stretchCollagen fiber orientationSuture strengthNative arteriesTissue equivalentsStrengthPropertiesCircumferential stretchMatrix contentVentilation-Based Decellularization System of the Lung
Tsuchiya T, Mendez J, Calle EA, Hatachi G, Doi R, Zhao L, Suematsu T, Nagayasu T, Niklason LE. Ventilation-Based Decellularization System of the Lung. BioResearch Open Access 2016, 5: 118-126. PMID: 27186445, PMCID: PMC4860652, DOI: 10.1089/biores.2016.0012.Peer-Reviewed Original ResearchCitationsAltmetricConceptsAirway groupPulmonary arteryDecellularized groupVessel groupPositive end-expiratory pressureEnd-expiratory pressureMHC class IWestern blot analysisRed blood cellsOrgan recipientsImmunohistochemical findingsNative lungPortal veinAdministration routeAlveolar wallsRat lungLungBlood leakageOrgan donationBlood cellsClass IDonated organsExtracellular matrixAirwayArterySterilization of Lung Matrices by Supercritical Carbon Dioxide
Balestrini JL, Liu A, Gard AL, Huie J, Blatt KM, Schwan J, Zhao L, Broekelmann TJ, Mecham RP, Wilcox EC, Niklason LE. Sterilization of Lung Matrices by Supercritical Carbon Dioxide. Tissue Engineering Part C Methods 2016, 22: 260-269. PMID: 26697757, PMCID: PMC4782026, DOI: 10.1089/ten.tec.2015.0449.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsLung matrixEnd-stage pulmonary failureExtracellular matrix depletionMajority of lungSupercritical carbon dioxidePulmonary failureLung tissueAcellular lungsCell engraftmentLungCurrent study resultsLung engineeringMatrix depletionTissueMechanical integrityCarbon dioxideScCO2 treatmentMechanical featuresDecellularized scaffoldTissue architectureSterile bufferSterility assurance levelDecellularized tissuesRegenerative medicine purposes
2014
Tissue‐Engineered Vascular Grafts Created From Human Induced Pluripotent Stem Cells
Sundaram S, One J, Siewert J, Teodosescu S, Zhao L, Dimitrievska S, Qian H, Huang AH, Niklason L. Tissue‐Engineered Vascular Grafts Created From Human Induced Pluripotent Stem Cells. Stem Cells Translational Medicine 2014, 3: 1535-1543. PMID: 25378654, PMCID: PMC4250208, DOI: 10.5966/sctm.2014-0065.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and ConceptsConceptsPluripotent stem cellsMesenchymal lineagesSmooth muscle cell differentiationMuscle cell differentiationStem cellsInduced pluripotent stem cellsNeural crest intermediateHuman induced pluripotent stem cellsMesenchymal progenitor cellsStem cell clonesCollagen-rich matrixCell differentiationVascular developmentHiPSC linesProgenitor cellsSmooth muscle cellsCell apoptosisHiPS cellsLineagesMesenchymal markersGeneration of graftMuscle cellsClonesTissue-engineered vascular graftsCellsInfluence of pH on Extracellular Matrix Preservation During Lung Decellularization
Tsuchiya T, Balestrini JL, Mendez J, Calle EA, Zhao L, Niklason LE. Influence of pH on Extracellular Matrix Preservation During Lung Decellularization. Tissue Engineering Part C Methods 2014, 20: 1028-1036. PMID: 24735501, PMCID: PMC4241865, DOI: 10.1089/ten.tec.2013.0492.Peer-Reviewed Original ResearchCitationsAltmetricMeSH Keywords and Concepts
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