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INFORMATION FOR

    Joseph Craft, MD

    Paul B. Beeson Professor of Medicine (Rheumatology) and Professor of Immunobiology
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    Additional Titles

    Paul B. Beeson Professor of Medicine, Internal Medicine: Rheumatology

    Program Director, Investigative Medicine, Internal Medicine: Rheumatology

    About

    Titles

    Paul B. Beeson Professor of Medicine (Rheumatology) and Professor of Immunobiology

    Paul B. Beeson Professor of Medicine, Internal Medicine: Rheumatology; Program Director, Investigative Medicine, Internal Medicine: Rheumatology

    Biography

    Dr. Craft is an AOA graduate of the University of North Carolina School of Medicine. He did medical and immunology training at Yale and is currently Paul B. Beeson Professor of Medicine and Professor of Immunobiology. He directs a laboratory devoted to understanding of host responses to pathogen challenge and to autoimmunity. His lab was among the 4 that simultaneously dissected the transcriptional regulation of T follicular helper cells, a finding listed among the most significant milestone discoveries in T cell development by the journal Nature and has made sentinel discoveries defining targets of the immune response in lupus and the role of T cells in driving pathogenic autoantibody and mechanisms of T cell mediate tissue damage in that disease. He has trained over 40 postdoctoral fellows and 26 PhD and MD/PhD graduate students including those currently in his lab. He is director of the Colton Center for Autoimmunity at Yale and has directed the Investigative Medicine MD to PhD program at Yale for over 20 years, training 70 MD/PhD students. Dr. Craft is a two-time NIH MERIT Awardee, 10-year NIH grants, recipient of the Yale Bohmfalk Basic Science Teaching Prize, an elected Fellow of American Association for the Advancement of Science, past chair of the Board of Scientific Counselors at NIH/NIAMS, and a former Pew Scholar in the Biomedical Sciences.

    Appointments

    • Rheumatology

      Professor
      Primary

    Other Departments & Organizations

    Education & Training

    Fellow
    Yale School of Medicine (1985)
    Resident
    Yale-New Haven Hospital (1980)
    Intern
    Yale-New Haven Hospital (1978)
    MD
    University of North Carolina (1977)
    MD
    University of North Carolina , School of Medicine (1977)

    Board Certifications

    • Rheumatology

      Certification Organization
      AB of Internal Medicine
      Latest Certification Date
      2008
      Original Certification Date
      1988
    • Internal Medicine

      Certification Organization
      AB of Internal Medicine
      Original Certification Date
      1980

    Research

    Overview

    Ongoing studies are targeted towards identification of the developmental pathways of CD4 T cells that provide B cell help and that promote inflammation, and dissection of their potential to promote autoimmunity and inflammation. Related work involves determination of tissue environmental factors that regulate T cell metabolism and effector function at inflammatory sites, such as tissues damaged in autoimmunity.

    Medical Research Interests

    Antigens, Differentiation, T-Lymphocyte; Autoimmune Diseases; Biology; Cytokines; Immunity; Investigative Techniques; Lupus Erythematosus, Systemic; Rheumatology

    Research at a Glance

    Yale Co-Authors

    Frequent collaborators of Joseph Craft's published research.

    Publications

    2024

    2023

    Clinical Trials

    Current Trials

    Academic Achievements & Community Involvement

    • activity

      Immune Tolerance Network

    • activity

      Lupus Clinical Investigators Network

    • honor

      Distinguished Innovator Award

    • honor

      MERIT Award

    • honor

      Paul B. Beeson Professor of Medicine

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    Administrative Support

    Events

    Apr 20258Tuesday