Murine interfollicular epidermal differentiation is gradualistic with GRHL3 controlling progression from stem to transition cell states
Lin Z, Jin S, Chen J, Li Z, Lin Z, Tang L, Nie Q, Andersen B. Murine interfollicular epidermal differentiation is gradualistic with GRHL3 controlling progression from stem to transition cell states. Nature Communications 2020, 11: 5434. PMID: 33116143, PMCID: PMC7595230, DOI: 10.1038/s41467-020-19234-6.Peer-Reviewed Original ResearchConceptsCell statesRNA velocity analysisSingle-cell RNA-seqTerminal differentiation genesStem cell stateInterfollicular epidermisStem cellsInterfollicular epidermal differentiationStem cell expansionDifferentiation genesRNA-seqCommitment pointTerminal differentiationGRHL3Epidermal differentiationCell expansionDifferentiationCellsTransition cellsWntGenesHomeostasis