1993
Expression of endogenous NMDAR1 transcripts without receptor protein suggests post-transcriptional control in PC12 cells.
Sucher N, Brose N, Deitcher D, Awobuluyi M, Gasic G, Bading H, Cepko C, Greenberg M, Jahn R, Heinemann S, Lipton S. Expression of endogenous NMDAR1 transcripts without receptor protein suggests post-transcriptional control in PC12 cells. Journal Of Biological Chemistry 1993, 268: 22299-22304. PMID: 8226739, DOI: 10.1016/s0021-9258(18)41528-1.Peer-Reviewed Original ResearchMeSH KeywordsAlternative SplicingAnimalsAstrocytesBase SequenceCell DifferentiationCell LineCells, CulturedDimethylphenylpiperazinium IodideDNA PrimersGene ExpressionGene Expression Regulation, NeoplasticGenetic VariationHippocampusHumansKidneyMacromolecular SubstancesMembrane PotentialsMolecular Sequence DataMolecular WeightNerve Growth FactorsN-MethylaspartatePC12 CellsPolymerase Chain ReactionReceptors, N-Methyl-D-AspartateRNA, MessengerSynaptic MembranesTranscription, GeneticTransfectionConceptsNMDAR1 proteinPC12 cellsPost-transcriptional controlPost-transcriptional mechanismsNative PC12 cellsParticular cell typeUndifferentiated rat pheochromocytoma (PC12) cellsExpression of RNAPC12 cell lineTranslational regulationIsoform CRat pheochromocytoma cellsNorthern hybridizationExpression vectorReceptor proteinCell typesIon channelsProteinFunctional NMDACell linesPheochromocytoma cellsCytomegalovirus promoterModel systemRNAExpression
1989
Characterization of nicotinic receptors in chick retina using a snake venom neurotoxin that blocks neuronal nicotinic receptor function
Loring R, Aizenman E, Lipton, Zigmond R. Characterization of nicotinic receptors in chick retina using a snake venom neurotoxin that blocks neuronal nicotinic receptor function. Journal Of Neuroscience 1989, 9: 2423-2431. PMID: 2746336, PMCID: PMC6569765, DOI: 10.1523/jneurosci.09-07-02423.1989.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsAnimals, NewbornBungarotoxinsChickensDimethylphenylpiperazinium IodideElectrophysiologyNeuronsNeurotoxinsNicotineReceptors, NicotinicRetinaConceptsNicotinic receptor functionNicotinic receptorsChick retinaNicotinic agonistsReceptor functionNeuronal nicotinic receptor functionIntact chick retinaFunctional nicotinic receptorsInner plexiform layerAutonomic gangliaGanglion cellsPlexiform layerCholine acetyltransferaseNeuronal bungarotoxinNeuromuscular antagonistsNicotinic functionNeuronal preparationsRetinaAgonistsReceptorsAntagonistSnake venom neurotoxinsVenom neurotoxinsLow affinityHigh affinity