1994
Identification of two cysteine residues that are required for redox modulation of the NMDA subtype of glutamate receptor
Sullivan J, Traynelis S, Chen H, Escobar W, Heinemann S, Lipton S. Identification of two cysteine residues that are required for redox modulation of the NMDA subtype of glutamate receptor. Neuron 1994, 13: 929-936. PMID: 7524561, DOI: 10.1016/0896-6273(94)90258-5.Peer-Reviewed Original ResearchMeSH KeywordsAnimalsCysteineDithiothreitolElectrophysiologyFemaleIon Channel GatingIon ChannelsMolecular Sequence DataMutagenesis, Site-DirectedN-MethylaspartateOocytesOxidation-ReductionPatch-Clamp TechniquesRatsReceptors, N-Methyl-D-AspartateRecombinant ProteinsSpermineStructure-Activity RelationshipXenopus
1989
Characterization of nicotinic receptors in chick retina using a snake venom neurotoxin that blocks neuronal nicotinic receptor function
Loring R, Aizenman E, Lipton, Zigmond R. Characterization of nicotinic receptors in chick retina using a snake venom neurotoxin that blocks neuronal nicotinic receptor function. Journal Of Neuroscience 1989, 9: 2423-2431. PMID: 2746336, PMCID: PMC6569765, DOI: 10.1523/jneurosci.09-07-02423.1989.Peer-Reviewed Original ResearchConceptsNicotinic receptor functionNicotinic receptorsChick retinaNicotinic agonistsReceptor functionNeuronal nicotinic receptor functionIntact chick retinaFunctional nicotinic receptorsInner plexiform layerAutonomic gangliaGanglion cellsPlexiform layerCholine acetyltransferaseNeuronal bungarotoxinNeuromuscular antagonistsNicotinic functionNeuronal preparationsRetinaAgonistsReceptorsAntagonistSnake venom neurotoxinsVenom neurotoxinsLow affinityHigh affinitySelective modulation of NMDA responses by reduction and oxidation
Aizenman E, Lipton S, Loring R. Selective modulation of NMDA responses by reduction and oxidation. Neuron 1989, 2: 1257-1263. PMID: 2696504, DOI: 10.1016/0896-6273(89)90310-3.Peer-Reviewed Original Research