1992
Desensitization of GABA-activated currents and channels in cultured cortical neurons
Frosch M, Lipton, Dichter M. Desensitization of GABA-activated currents and channels in cultured cortical neurons. Journal Of Neuroscience 1992, 12: 3042-3053. PMID: 1379634, PMCID: PMC6575652, DOI: 10.1523/jneurosci.12-08-03042.1992.Peer-Reviewed Original ResearchConceptsRate of desensitizationPresence of agonistInhibitory synaptic activationCultured cortical neuronsWhole-cell recording modeApplication of GABAWhole-cell modeDesensitization of GABACortical inhibitionCortical neuronsGABA responsesNeocortical neuronsSynaptic activationSame neuronsGABASingle-channel responsesDesensitizationDesensitization processNeuronsTrue declineAgonistsMembrane conductanceCell culturesRecording modeDose dependence
1988
Characterization of GABA- and glycine-induced currents of solitary rodent retinal ganglion cells in culture
Tauck D, Frosch M, Lipton S. Characterization of GABA- and glycine-induced currents of solitary rodent retinal ganglion cells in culture. Neuroscience 1988, 27: 193-203. PMID: 3200439, DOI: 10.1016/0306-4522(88)90230-8.Peer-Reviewed Original ResearchConceptsGanglion cellsBicuculline methiodideRodent retinal ganglion cellsReversal potentialRetinal ganglion cellsWhole-cell recordingsAgonist-induced currentsRodent retinaD-tubocurarineMicroM GABAMicroM glycineReceptor desensitizationGABAPatch electrodeDesensitizationStrychnineMembrane conductancePicrotoxininMethiodideTaurineCellsSolitary cellsSpace clampTissue cultureResponse