Association of Strong Immune Responses to PPE Protein Rv1168c with Active Tuberculosis â–¿
Khan N, Alam K, Nair S, Valluri VL, Murthy KJ, Mukhopadhyay S. Association of Strong Immune Responses to PPE Protein Rv1168c with Active Tuberculosis â–¿. MSphere 2008, 15: 974-980. PMID: 18400969, PMCID: PMC2446626, DOI: 10.1128/cvi.00485-07.Peer-Reviewed Original ResearchConceptsTB patientsESAT-6Sensitized peripheral blood mononuclear cellsStrong gamma interferon responseSmear-negative pulmonary TBPeripheral blood mononuclear cellsExtrapulmonary TB casesSerodiagnosis of TBBlood mononuclear cellsPotent T-cell antigenControl of TBT-cell antigensGamma interferon responseStrong immune responseConventional diagnostic testsConventional enzyme immunoassayActive TBMycobacterium bovis BCGPulmonary TBActive tuberculosisTB casesTuberculosis infectionMononuclear cellsImmune responseStrong immunoreactivity