The C. elegans anchor cell transcriptome: ribosome biogenesis drives cell invasion through basement membrane
Costa D, Kenny-Ganzert I, Chi Q, Park K, Kelley L, Garde A, Matus D, Park J, Yogev S, Goldstein B, Gibney T, Pani A, Sherwood D. The C. elegans anchor cell transcriptome: ribosome biogenesis drives cell invasion through basement membrane. Development 2023, 150 PMID: 37039075, PMCID: PMC10259517, DOI: 10.1242/dev.201570.Peer-Reviewed Original ResearchConceptsRibosome biogenesisCell invasionAnchor cell invasionTranslation of proteinsFocused RNAi screenGene expression profilesAC invasionRibosome productionRNAi screenEndomembrane systemBM transmigrationRibosomal proteinsSec61 transloconCell transcriptomeBasement membrane barriersGene enrichmentExpression profilesTumor proteinTranscriptomeER stressCancer progressionInvasion regulatorsMembrane barrierProteinBiogenesis