Progress towards Understanding the Mosquito-Borne Virus Life Cycle
Yu X, Zhu Y, Xiao X, Wang P, Cheng G. Progress towards Understanding the Mosquito-Borne Virus Life Cycle. Trends In Parasitology 2019, 35: 1009-1017. PMID: 31669148, DOI: 10.1016/j.pt.2019.09.006.Peer-Reviewed Original ResearchLack of efficacy of ivermectin for prevention of a lethal Zika virus infection in a murine system
Ketkar H, Yang L, Wormser GP, Wang P. Lack of efficacy of ivermectin for prevention of a lethal Zika virus infection in a murine system. Diagnostic Microbiology And Infectious Disease 2019, 95: 38-40. PMID: 31097261, PMCID: PMC6697611, DOI: 10.1016/j.diagmicrobio.2019.03.012.Peer-Reviewed Original ResearchConceptsZika virus infectionAnti-Zika virus activityVirus infectionAnimal modelsZika virusLethal Zika Virus InfectionIFNAR1 knockout miceZika virus strainLack of efficacyEffectiveness of ivermectinLethal infectionKnockout miceVirus activityAntiviral activityMurine systemVirus strainsDrug ivermectinInfectionIvermectinStudy limitationsPreventionVirusSenegal strainMice