Minhua Wang, MD, PhD, MS
Assistant Professor of PathologyCards
About
Research
Publications
2025
Selection of neuroendocrine markers in diagnostic workup of neuroendocrine neoplasms: The real‐world data and machine learning model algorithms
Tang H, Xia H, Sun N, Hernandez P, Wang M, Adeniran A, Cai G. Selection of neuroendocrine markers in diagnostic workup of neuroendocrine neoplasms: The real‐world data and machine learning model algorithms. Cancer Cytopathology 2025, 133: e70018. PMID: 40289395, DOI: 10.1002/cncy.70018.Peer-Reviewed Original ResearchConceptsMachine learning algorithmsReal-world dataLearning algorithmsNeural networkRandom forestNeural network modelNeuroendocrine neoplasmsAUC-ROCMachine learning modelsNeuroendocrine markersDiagnostic workupLearning modelsMachine learning modeling algorithmsNetwork modelDiagnosis of neuroendocrine neoplasmsModeling algorithmAlgorithmArea under the curveMachineArea under the curve of receiver operating characteristic curvesReceiver operating characteristic curveNetworkNEC casesCytology casesNon-NENs401 Prognostic Value of Pelvic Washing Cytology in Early-Stage Endometrial Cancer: A 10-Year Single-Institute Cohort Study
Wang M, Abi-Raad R, Krishnamurti U, Cai G, Adeniran A, Sun T. 401 Prognostic Value of Pelvic Washing Cytology in Early-Stage Endometrial Cancer: A 10-Year Single-Institute Cohort Study. Laboratory Investigation 2025, 105: 102628. DOI: 10.1016/j.labinv.2024.102628.Peer-Reviewed Original Research341 Comparative Assessment of Claudin-4, MOC-31, and BerEP4 Immunomarkers in Diagnostic Workup of Metastatic Carcinoma in Serous Fluid Specimens
Haque M, Kaur H, Wang M, Cai G. 341 Comparative Assessment of Claudin-4, MOC-31, and BerEP4 Immunomarkers in Diagnostic Workup of Metastatic Carcinoma in Serous Fluid Specimens. Laboratory Investigation 2025, 105: 102568. DOI: 10.1016/j.labinv.2024.102568.Peer-Reviewed Original Research411 Correlation of ACR-TI-RADS, Cytology, Histology, and Molecular studies
Yu S, Wang M, Langdon J, Sinard J, Cai G, Prasad M, Adeniran A. 411 Correlation of ACR-TI-RADS, Cytology, Histology, and Molecular studies. Laboratory Investigation 2025, 105: 102638. DOI: 10.1016/j.labinv.2024.102638.Peer-Reviewed Original Research
2024
TRPS1 expression in cytologic specimens of salivary duct carcinoma and other salivary gland tumors
Wang M, Cai G, Gilani S. TRPS1 expression in cytologic specimens of salivary duct carcinoma and other salivary gland tumors. Annals Of Diagnostic Pathology 2024, 74: 152406. PMID: 39547127, DOI: 10.1016/j.anndiagpath.2024.152406.Peer-Reviewed Original ResearchConceptsTRPS1 expressionSalivary duct carcinomaTrichorhinophalangeal syndrome type 1Salivary gland tumorsBreast carcinomaMucoepidermoid carcinomaSecretory carcinomaWarthin's tumorDuct carcinomaGland tumorsSalivary duct carcinoma casesCase of secretory carcinomaAcinic cell carcinomaAdenoid cystic carcinomaBasal cell adenomaImmunophenotypic featuresCystic carcinomaSurgical specimensCell adenomaCell carcinomaCytology casesCytology specimensPleomorphic adenomaCell blocksBreast cancerThe World Health Organization System for Reporting Pancreaticobiliary Cytopathology: Standardized Categories and Practical Approaches to Pancreatic Lesions
Wang M, Lozano M, Cai G. The World Health Organization System for Reporting Pancreaticobiliary Cytopathology: Standardized Categories and Practical Approaches to Pancreatic Lesions. Journal Of Clinical And Translational Pathology 2024, 4: 122-135. PMID: 40191142, PMCID: PMC11969574, DOI: 10.14218/jctp.2024.00034.Peer-Reviewed Original Research
2023
The International System for Reporting Serous Fluid Cytopathology—An Updated Review
Wang M, Chandra A, Cai G. The International System for Reporting Serous Fluid Cytopathology—An Updated Review. Journal Of Clinical And Translational Pathology 2023, 3: 160-177. PMID: 39372684, PMCID: PMC11451941, DOI: 10.14218/jctp.2023.00025.Peer-Reviewed Original ResearchRisk of malignancyPotential diagnostic pitfallsReproducibility of reportsInternational Academy of CytologySerous Fluid CytopathologySerous fluid specimensSerous fluid samplesAmerican Society of CytopathologyDiagnostic pitfallsFluid specimensMalignant categoriesFive-tier systemMalignancyDiagnostic criteriaFluid samplesAmerican SocietyBody Cavity Fluid Cytology
Wang M. Body Cavity Fluid Cytology. 2023, 57-71. DOI: 10.1007/978-3-031-44289-6_5.Peer-Reviewed Original ResearchSerous effusionsMinimally invasive procedureExcessive accumulation of fluidAspiration of fluidAccumulation of fluidLymphocytic effusionsBenign causesTuberculous effusionsNeedle aspirationSystemic lupusIdentifying malignancyChylous effusionInvasive proceduresPeritoneal cavityCytologic evaluationMesothelial cellsEffusionSerous fluidInflammatory effusionsEosinophilic effusionsApplication of the International System for Reporting Serous Fluid Cytopathology to pericardial fluid: Root cause analysis of indeterminate diagnoses, cytohistological correlation, and assessment of malignancy risk
Wang M, Sun T, Jiao J, Wang H. Application of the International System for Reporting Serous Fluid Cytopathology to pericardial fluid: Root cause analysis of indeterminate diagnoses, cytohistological correlation, and assessment of malignancy risk. Cancer Cytopathology 2023, 131: 433-441. PMID: 36973963, DOI: 10.1002/cncy.22696.Peer-Reviewed Original ResearchDiagnosis of acinic cell carcinoma of the salivary gland on cytology specimens: Role of NOR‐1 (NR4A3) immunohistochemistry
Meiklejohn K, Hrones M, Wang M, Prasad M, Cai G, Adeniran A, Gilani S. Diagnosis of acinic cell carcinoma of the salivary gland on cytology specimens: Role of NOR‐1 (NR4A3) immunohistochemistry. Cytopathology 2023, 34: 219-224. PMID: 36825365, DOI: 10.1111/cyt.13222.Peer-Reviewed Original Research
Clinical Care
Overview
Minhua Wang, MD, PhD, is a pathologist with a clinical focus on cytopathology and gynecological pathology. Much of her clinical work involves studying specimens with a microscope and reviewing ancillary tests. As a cytopathologist, she studies fluid, smear, and aspiration specimens to make a diagnosis. In the gynecological pathology service, she examines surgical tissue samples from the female reproductive tract to look for the presence of malignancy.
Dr. Wang says she was drawn to pathology because she saw it as an important link in patient care. “The pathological diagnosis provides clinicians with crucial information in their decision-making regarding disease management,” she says. She plays a key role in rendering definitive cancer diagnoses and describes it as “a privilege” to assist clinicians in the care of cancer patients.
In addition to her clinical work as a pathologist, Dr. Wang is engaged in research projects to investigate certain biomarkers and their utility in enhancing diagnostic accuracy for certain types of cancers and/or their prognostic value using cytology specimens. She also is involved in other cytohistological validation studies that aim to improve pathological diagnostic accuracy to better guide clinical decision-making.
Clinical Specialties
Board Certifications
Cytopathology
- Certification Organization
- AB of Pathology
- Original Certification Date
- 2019
Anatomic & Clinical Pathology
- Certification Organization
- AB of Pathology
- Original Certification Date
- 2017
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Academic Office
789 Howard Avenue, Ste CB 506D
New Haven, CT 06519