2021
Trends in Early Graft Failure Leading to Regrafting After Endothelial Keratoplasty in the United States
Fliotsos MJ, Campbell JA, Li X, Engstrom MB, Stoeger CG, McClory C, Titus MS, Johnson P, Johnston KB, Fischer T, Brooks LK, Montoya MM, Glasser DB, Akpek EK, Srikumaran D. Trends in Early Graft Failure Leading to Regrafting After Endothelial Keratoplasty in the United States. Cornea 2021, 41: 833-839. PMID: 34369391, PMCID: PMC8818059, DOI: 10.1097/ico.0000000000002831.Peer-Reviewed Original ResearchConceptsDescemet membrane endothelial keratoplastyEarly graft failureGraft failureEndothelial keratoplastyEye bankStudy periodHigher donor ageDonor tissue characteristicsSurgical learning curveEndothelial Keratoplasty TissueLinear mixed model analysisDSAEK graftsRecipient ageAdverse eventsDescemet strippingBorderline significanceGraft casesGraft volumeSubset analysisDonor ageMixed model analysisKeratoplastyDSAEKTissue characteristicsRecipient level
2020
Peripheral-to-central ratio of Guttae: validity and reliability of an objective method to characterize severity of Fuchs endothelial corneal dystrophy
Bajaj RP, Fliotsos MJ, Pradeep T, Eghrari AO. Peripheral-to-central ratio of Guttae: validity and reliability of an objective method to characterize severity of Fuchs endothelial corneal dystrophy. Graefe's Archive For Clinical And Experimental Ophthalmology 2020, 259: 685-690. PMID: 33128674, PMCID: PMC7904627, DOI: 10.1007/s00417-020-04985-1.Peer-Reviewed Original ResearchMeSH KeywordsEndothelium, CornealFuchs' Endothelial DystrophyHumansPilot ProjectsReproducibility of ResultsROC CurveSlit LampConceptsFuchs endothelial corneal dystrophyEndothelial corneal dystrophyCorneal dystrophySeverity scoreInter-rater reliabilitySevere diseaseClinical severity scoreCentral ratioGood inter-rater reliabilityAffected eyeFuchs' dystrophyMethodsFifteen patientsClinical severitySevere casesIndependent gradersPilot studyRatio cutoffSeverityDystrophyGuttaeDiseaseBaselineScoresBottom 4Objective methodQualitative and Quantitative Analysis of the Corneal Endothelium With Smartphone Specular Microscopy.
Fliotsos MJ, Deljookorani S, Dzhaber D, Chandan S, Ighani M, Eghrari AO. Qualitative and Quantitative Analysis of the Corneal Endothelium With Smartphone Specular Microscopy. Cornea 2020, 39: 924-929. PMID: 32068608, PMCID: PMC8064114, DOI: 10.1097/ico.0000000000002277.Peer-Reviewed Original ResearchMeSH KeywordsAdultCell CountEndothelium, CornealFemaleHealthy VolunteersHumansMaleMicroscopyReproducibility of ResultsSmartphoneYoung AdultConceptsEndothelial cell countSlit-lamp biomicroscopeCorneal endotheliumSpecular microscopyCell countSpecular microscopeSingle academic centerAverage intraclass correlation coefficientIntraclass correlation coefficientBland-Altman analysisAcademic centersEndotheliumMean differenceHealthy participantsCells/Set of eyesBiomicroscopeProportional biasEyesCountParticipantsLinear regression