2005
Short report: Phylogenetic relationships of the anthropophilic Plasmodium falciparum malaria vectors in Africa.
MARSHALL J, POWELL J, Caccone A. Short report: Phylogenetic relationships of the anthropophilic Plasmodium falciparum malaria vectors in Africa. American Journal Of Tropical Medicine And Hygiene 2005, 73: 749-52. PMID: 16222020, DOI: 10.4269/ajtmh.2005.73.749.Peer-Reviewed Original ResearchConceptsNumber of speciesMalaria vectorsAfrican mosquito vectorsMosquito vectorsNuclear genesParaphyletic relationshipSubgenus CelliaPhylogenetic relationshipsPhylogenetic analysisAdditional speciesStatistical supportSpeciesPlasmodium falciparumP. falciparumCausative agentCelliaFalciparumGenesHistorical associationVectorBayesian methods
1999
Characterization of the soluble guanylyl cyclase β‐subunit gene in the mosquito Anopheles gambiae
Caccone A, Garcia B, Mathiopoulos K, Min G, Moriyama E, Powell J. Characterization of the soluble guanylyl cyclase β‐subunit gene in the mosquito Anopheles gambiae. Insect Molecular Biology 1999, 8: 23-30. PMID: 9927171, DOI: 10.1046/j.1365-2583.1999.810023.x.Peer-Reviewed Original ResearchConceptsAnopheles gambiaeDeduced amino acid sequenceA. gambiae genomeMosquito Anopheles gambiaeThird codon positionInternal stop codonBeta-subunit geneAmino acid sequenceGambiae genomeGambiae genesGene structureTransposable elementsFifth intronCodon positionsNoncoding regionsSubunit geneAcid sequenceFlanking regionsC-terminusFunctional domainsGenomic DNAStop codonHigh similarityGenesFirst detailed description
1998
Gene length and codon usage bias in Drosophila melanogaster , Saccharomyces cerevisiae and Escherichia coli
Moriyama E, Powell J. Gene length and codon usage bias in Drosophila melanogaster , Saccharomyces cerevisiae and Escherichia coli. Nucleic Acids Research 1998, 26: 3188-3193. PMID: 9628917, PMCID: PMC147681, DOI: 10.1093/nar/26.13.3188.Peer-Reviewed Original ResearchConceptsCodon usage biasUsage biasGene lengthDrosophila melanogasterLong genesHigher codon usage biasRibosomal protein genesEscherichia coliSynonymous codon usage biasD. melanogasterTranslational selectionShort genesProtein geneTranslational efficiencyEukaryotesMelanogasterGenesExpression levelsSaccharomycesEffective numberColiProkaryotesCodonOrganismsProtein
1997
Synonymous substitution rates in Drosophila: Mitochondrial versus nuclear genes
Moriyama E, Powell J. Synonymous substitution rates in Drosophila: Mitochondrial versus nuclear genes. Journal Of Molecular Evolution 1997, 45: 378-391. PMID: 9321417, DOI: 10.1007/pl00006243.Peer-Reviewed Original ResearchConceptsSynonymous substitution ratesHigher synonymous substitution ratesNuclear genesMitochondrial genesSubstitution ratesDivergence time estimatesBase composition biasNuclear genomeSynonymous ratesHeterogeneity of ratesRelated speciesCodon usageBase compositionComposition biasMutation rateGenesDrosophilaMtDNATime estimatesTurnover rateTransversionsGenomeSpeciesDivergenceSubstitution numberEvolution of codon usage bias in Drosophila
Powell J, Moriyama E. Evolution of codon usage bias in Drosophila. Proceedings Of The National Academy Of Sciences Of The United States Of America 1997, 94: 7784-7790. PMID: 9223264, PMCID: PMC33704, DOI: 10.1073/pnas.94.15.7784.Peer-Reviewed Original ResearchConceptsCodon usage biasHigher codon usage biasUsage biasBiased genesMutation biasSynonymous sitesCodon biasAmino acidsLow codon usage biasDrosophila genesDNA evolutionEffect of recombinationSmall geneIndividual amino acidsLong genesSynonymous substitutionsTRNA poolPreferred codonsSynonymous polymorphismWobble positionDrosophilaSame nucleotideSelection hypothesisGenesLines of evidence
1995
An anchored restriction-mapping approach applied to the genetic analysis of the Anopheles gambiae malaria vector complex 1.
Mathiopoulos K, Powell J, McCutchan T. An anchored restriction-mapping approach applied to the genetic analysis of the Anopheles gambiae malaria vector complex 1. Molecular Biology And Evolution 1995, 12: 103-112. PMID: 7877485, DOI: 10.1093/oxfordjournals.molbev.a040179.Peer-Reviewed Original ResearchConceptsAnopheles gambiae complexRare restriction sitesMolecular variationPhylogenetic analysisRRNA geneSingle Southern blotGenetic analysisGambiae complexRestriction mapSouthern blotSystematic purposesRestriction sitesPartial digestionMalaria vectorsGenomeSpeciesIndependent regionsTreesMtDNAGenesEnzymeRegionBlotDigestionComplexes
1993
Conservation and change of the developmentally crucial fushi tarazu gene in Drosophila
Maier D, Sperlich D, Powell J. Conservation and change of the developmentally crucial fushi tarazu gene in Drosophila. Journal Of Molecular Evolution 1993, 36: 315-326. PMID: 8100278, DOI: 10.1007/bf00182179.Peer-Reviewed Original ResearchConceptsFushi tarazu geneMolecular developmental studiesLittle evolutionary conservationDNA sequence 5'Control elementsAntennapedia complexGenus DrosophilaFtz geneEvolutionary conservationMajor subgeneraGene homologsEvolutionary timeImportant DNA sequencesSequence conservationDevelopmental studiesDNA elementsEvolutionary changeDNA regionsDNA sequencesExonic sequencesProper regulationDrosophilaSequence 5GenesImportant sequences
1990
Regulation of the segmentation gene fushi tarazu has been functionally conserved in Drosophila.
Maier D, Preiss A, Powell J. Regulation of the segmentation gene fushi tarazu has been functionally conserved in Drosophila. The EMBO Journal 1990, 9: 3957-3966. PMID: 2174353, PMCID: PMC552166, DOI: 10.1002/j.1460-2075.1990.tb07616.x.Peer-Reviewed Original ResearchConceptsSegmentation gene fushi tarazuFtz geneFushi tarazuD. melanogasterUpstream elementEvolution of DrosophilaEntire regulatory networksSegmentation genesMillions of yearsRegulatory networksRegulatory elementsStrong homologySpecific enhancersGene productsUpstream regionUnrelated sequencesTransformation experimentsGenesDrosophilaMelanogasterOverall organizationRegulationFTZHomologuesHomology
1980
Genetics and the Origin of a Vector Population: Aedes aegypti, a Case Study
Powell J, Tabachnick W, Arnold J. Genetics and the Origin of a Vector Population: Aedes aegypti, a Case Study. Science 1980, 208: 1385-1387. PMID: 7375945, DOI: 10.1126/science.7375945.Peer-Reviewed Original ResearchConceptsEnzyme-coding genesMosquito Aedes aegyptiAedes aegyptiPopulation geneticsGenetic differencesVector populationsWorldwide distributionVector-borne diseasesGeneticsAegyptiSubspeciesGeographic regionsGenesPopulationSuch studiesMultivariate discriminant analysisOriginPopulation sampleGeneral applicability
1979
POPULATION GENETICS OF DROSOPHILA AMYLASE. I. GENETIC CONTROL OF TISSUE-SPECIFIC EXPRESSION IN D. PSEUDOOBSCURA
Powell J, Lichtenfels J. POPULATION GENETICS OF DROSOPHILA AMYLASE. I. GENETIC CONTROL OF TISSUE-SPECIFIC EXPRESSION IN D. PSEUDOOBSCURA. Genetics 1979, 92: 603-612. PMID: 488706, PMCID: PMC1213979, DOI: 10.1093/genetics/92.2.603.Peer-Reviewed Original ResearchConceptsTissue-specific expressionAdult midgutThird chromosomeGenetic controlThird-chromosome inversionsDrosophila amylaseD. pseudoobscuraDrosophila pseudoobscuraD. melanogasterChromosome inversionsPopulation geneticsRegulatory genesSingle locusGenetic elementsAmy expressionGenesPseudoobscuraPartial linkageChromosomesMidgutExpressionEnzymeMelanogasterLociGenetics
1972
Enzyme variability in the Drosophila willistoni Group. V. Genic variation in natural populations of Drosophila equinoxialis*
Ayala F, Powell J, Tracey M. Enzyme variability in the Drosophila willistoni Group. V. Genic variation in natural populations of Drosophila equinoxialis*. Genetics Research 1972, 20: 19-42. PMID: 5084410, DOI: 10.1017/s0016672300013562.Peer-Reviewed Original ResearchConceptsGenetic variationD. equinoxialisNatural populationsAllelic variationDrosophila willistoni groupMdh-2 locusStarch gel electrophoresisGenic variationD. willistoniWillistoni groupNeotropical speciesNatural selectionGenetic variabilityEnzyme variabilityEst-3LociSpeciesGene frequenciesSame alleleCommon allelesAllelesAllelic frequenciesLocalitiesWillistoniGenes