Deciphering the essentiality and function of the anti‐σM factors in Bacillus subtilis
Zhao H, Roistacher D, Helmann J. Deciphering the essentiality and function of the anti‐σM factors in Bacillus subtilis. Molecular Microbiology 2019, 112: 482-497. PMID: 30715747, PMCID: PMC6679829, DOI: 10.1111/mmi.14216.Peer-Reviewed Original ResearchMeSH KeywordsBacillus subtilisBacterial ProteinsDNA-Directed RNA PolymerasesGene Expression Regulation, BacterialPromoter Regions, GeneticSigma FactorConceptsAnti-sigma factorAlternative sigma factorSigma factorRNA polymerase core enzymeCell wall homeostasisStress conditionsSigma factor activitySevere growth defectBeta prime subunitCell wall synthesisAbility of mutationsDepletion strainCore enzymeTranscriptional landscapeSuppressor mutationsGrowth defectMerodiploid strainsRNA polymeraseWall synthesisMutations mapWall homeostasisAccessory proteinsPositive feedback loopBacillus subtilisFactor activity