George Dragoi, MD, PhD
Associate Professor of Psychiatry and of NeuroscienceCards
About
Research
Overview
Learned information is not encoded in isolation, but is integrated within a network of preexisting knowledge stored in patterns of neuronal ensemble functional connectivity. Our immediate goal is to investigate:
1. How these patterns emerge during development
2. How are they utilized in behavior
3. How are they disrupted in neuropsychiatric diseases.
The hippocampus, a brain structure initially implicated in rapid learning and formation of episodic memory, is now recognized to encode internally-generated spatial-temporal sequence representations. Its dysfunctions have resulted in anterograde amnesia, impaired imagining of new experiences, and hallucinations. Achieving our goal will be facilitated by our use of electrophysiological recordings of ensembles of neurons in behaving mice and rats, optogenetic manipulation of neurons, optical imaging of neuronal ensembles, and computational methods for decoding neuronal population activity.
Medical Research Interests
Public Health Interests
News
News
- October 03, 2025
The Brain Navigates New Spaces by ‘Flickering’ Between Reality and Old Mental Maps
- September 06, 2025Source: Nature Communications
Generative Emergence of Non-Local Representations in the Hippocampus
- April 10, 2025Source: Scientific Sense Podcast
Dragoi on Memory Storage and Retrieval
- September 30, 2024Source: Nature Communications
Experience of Euclidean Geometry Sculpts the Development and Dynamics of Rodent Hippocampal Sequential Cell Assemblies
Get In Touch
Contacts
Dragoi Lab
100 College Street
New Haven, CT 06510
United States