1987
Children of Depressed Parents: Increased Psychopathology and Early Onset of Major Depression
Weissman M, Gammon G, John K, Merikangas K, Warner V, Prusoff B, Sholomskas D. Children of Depressed Parents: Increased Psychopathology and Early Onset of Major Depression. JAMA Psychiatry 1987, 44: 847-853. PMID: 3662741, DOI: 10.1001/archpsyc.1987.01800220009002.Peer-Reviewed Original ResearchConceptsMajor depressionFemale subjectsProband's parentsYears of agePrepubertal depressionPrognostic significanceMean ageOverall prevalenceLower riskClinical strategiesPsychiatric diagnosisPsychiatric treatmentSymptom profilesDepressed probandsNormal probandsDepressed parentsPoor social functioningSubstance abuseEarly onsetDepressed childrenSubject diagnosisDiagnosisDepressionChild psychiatristsSocial functioning
1986
Depressed Parents and Their Children: General Health, Social, and Psychiatric Problems
Weissman M, John K, Merikangas K, Prusoff B, Wickramaratne P, Gammon G, Angold A, Warner V. Depressed Parents and Their Children: General Health, Social, and Psychiatric Problems. JAMA Pediatrics 1986, 140: 801-805. PMID: 3728409, DOI: 10.1001/archpedi.1986.02140220083038.Peer-Reviewed Original ResearchConceptsMajor depressionPsychiatric disordersDepressed parentsAdverse perinatal eventsMore medical problemsDirect clinical implicationsMore suicide attemptsMore convulsionsPerinatal eventsHead injuryGeneral healthChronic illnessPrevalent disorderPsychiatric problemsClinical implicationsMedical problemsSuicide attemptsSociodemographic backgroundDisordersFurther studiesSignificant differencesDepressionChildrenMore distressDevelopmental landmarks