Growth inhibition in G1 and altered expression of cyclin D1 and p27kip‐1 after forced connexin expression in lung and liver carcinoma cells
Koffler L, Roshong S, Park I, Cesen‐Cummings K, Thompson D, Dwyer‐Nield L, Rice P, Mamay C, Malkinson A, Ruch R. Growth inhibition in G1 and altered expression of cyclin D1 and p27kip‐1 after forced connexin expression in lung and liver carcinoma cells. Journal Of Cellular Biochemistry 2000, 79: 347-354. PMID: 10972973, DOI: 10.1002/1097-4644(20001201)79:3<347::aid-jcb10>3.0.co;2-2.Peer-Reviewed Original ResearchConceptsGap junctional intercellular communicationRat liver epithelial cellsConnexin expressionE9 cellsLiver epithelial cellsGrowth controlDefective growth controlCyclin D1Growth-related functionsTransfection of Cx43Cell cycle regulatorsCell linesEpithelial cellsGap junction proteinCarcinoma cellsMouse lung carcinoma cellsJunctional intercellular communicationLess cyclin D1Cell cycle distributionCycle regulatorsForced expressionIntercellular communicationS phaseP27kip-1Lung carcinoma cells