Ya-Chi Ho

Dr. Ho takes a molecular virology, single-cell and genomics approaches to examine HIV persistence and develop HIV cure strategies. Using clinical samples from HIV-infected individuals, the Ho lab investigates host-HIV interactions with particular interests in HIV-1-host RNA landscape (using single-cell RNAseq), CD4 T cell expansion dynamics, HIV-host genome interactions, and HIV-1-specific silencing, and immune escape mechanisms. Dr. Ho was a board-certified infectious disease attending physician in Taiwan. She received her PhD (2013) and postdoctoral training at Johns Hopkins University School of Medicine in Dr. Robert F. Siliciano's lab. She was a tenure track instructor (2016) and then an assistant professor (2017) at Johns Hopkins School of Medicine before she joined Yale School of Medicine in September 2017. As a investigator of the AIDS Clinical Trial Group (ACTG) and the BEAT HIV Martin Delaney Collaboratory, she actively collaborate with geneticists, bioinformaticians, immunologists and physicians to study HIV-1 persistence. She is currently funded by an NIH R01 grant and an NIH R61/R33 grant as the Principal Investigator.