Nai Yang Yeat, PhD
Postdoctoral AssociateAbout
Research
Publications
2025
Extracellular vesicles: biogenesis mechanism and impacts on tumor immune microenvironment
Yeat N, Chen R. Extracellular vesicles: biogenesis mechanism and impacts on tumor immune microenvironment. Journal Of Biomedical Science 2025, 32: 85. PMID: 40908470, PMCID: PMC12412255, DOI: 10.1186/s12929-025-01182-2.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsBro1 proteins determine tumor immune evasion and metastasis by controlling secretion or degradation of multivesicular bodies
Yeat N, Liu L, Chang Y, Lai C, Chen R. Bro1 proteins determine tumor immune evasion and metastasis by controlling secretion or degradation of multivesicular bodies. Developmental Cell 2025, 60: 2114-2130.e9. PMID: 40185104, DOI: 10.1016/j.devcel.2025.03.008.Peer-Reviewed Original ResearchActinsAnimalsCalcium-Binding ProteinsCapZ Actin Capping ProteinCell Cycle ProteinsCell LineEndosomal Sorting Complexes Required for TransportExosomesGTP-Binding ProteinsHumansMaleMiceMice, Inbred C57BLMice, Inbred NODMice, NudeMultivesicular BodiesNeoplasm MetastasisNeoplasms, ExperimentalProtein Tyrosine Phosphatases, Non-ReceptorTumor Escape
2024
Correction: PTPN23 ubiquitination by WDR4 suppresses EGFR and c-MET degradation to define a lung cancer therapeutic target
Singh S, Yeat N, Wang Y, Lin S, Kuo I, Wu K, Wang W, Wang W, Su W, Wang Y, Chen R. Correction: PTPN23 ubiquitination by WDR4 suppresses EGFR and c-MET degradation to define a lung cancer therapeutic target. Cell Death & Disease 2024, 15: 468. PMID: 38956428, PMCID: PMC11219715, DOI: 10.1038/s41419-024-06747-x.Commentaries, Editorials and Letters
2023
PTPN23 ubiquitination by WDR4 suppresses EGFR and c-MET degradation to define a lung cancer therapeutic target
Singh S, Yeat N, Wang Y, Lin S, Kuo I, Wu K, Wang W, Wang W, Su W, Wang Y, Chen R. PTPN23 ubiquitination by WDR4 suppresses EGFR and c-MET degradation to define a lung cancer therapeutic target. Cell Death & Disease 2023, 14: 671. PMID: 37821451, PMCID: PMC10567730, DOI: 10.1038/s41419-023-06201-4.Peer-Reviewed Original ResearchTRABID inhibition activates cGAS/STING-mediated anti-tumor immunity through mitosis and autophagy dysregulation
Chen Y, Chen H, Wang W, Chen H, Huang W, Kao C, Lee S, Yeat N, Yan R, Chan S, Wu K, Chen R. TRABID inhibition activates cGAS/STING-mediated anti-tumor immunity through mitosis and autophagy dysregulation. Nature Communications 2023, 14: 3050. PMID: 37237031, PMCID: PMC10220035, DOI: 10.1038/s41467-023-38784-z.Peer-Reviewed Original Research
Get In Touch
Contacts
Mobile Phone Number
Locations
West Campus Molecular Innovations Center
Lab
600 West Campus Drive, Fl 3, Rm 319
West Haven, CT 06516