Kevin B. Givechian, PhD
About
Research
Publications
2025
ImmunoStruct enables multimodal deep learning for immunogenicity prediction
Givechian K, Rocha J, Liu C, Yang E, Tyagi S, Greene K, Ying R, Caron E, Iwasaki A, Krishnaswamy S. ImmunoStruct enables multimodal deep learning for immunogenicity prediction. Nature Machine Intelligence 2025, 8: 70-83. DOI: 10.1038/s42256-025-01163-y.Peer-Reviewed Original ResearchTranexamic Acid in Body Contouring Surgery: A Systematic Review and Meta-Analysis
Fijany A, Holan C, Troia T, Montorfano L, Mubang R, Givechian K, Karagoz H, Martinez-Jorge J, Perdikis G, Connor L, Slater E. Tranexamic Acid in Body Contouring Surgery: A Systematic Review and Meta-Analysis. Aesthetic Surgery Journal 2025, 45: 1026-1034. PMID: 40509914, PMCID: PMC12550359, DOI: 10.1093/asj/sjaf112.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2024
Success of Bone Ossification After Posterior Vault Distraction Osteogenesis in Patients With Craniosynostosis
Sayadi J, Lujan-Hernandez J, Givechian K, Mackay D, Lorenz H, Grant G, Mahaney K, Hong D, Khosla R. Success of Bone Ossification After Posterior Vault Distraction Osteogenesis in Patients With Craniosynostosis. Journal Of Craniofacial Surgery 2024, 36: 870-875. PMID: 39819807, DOI: 10.1097/scs.0000000000010844.Peer-Reviewed Original Research
2023
Complication Profiles of Smooth vs Textured Tissue Expanders in Breast Reconstruction: A Systematic Review and Meta-Analysis
Fijany A, Chaker S, Hung Y, Zago I, Friedlich N, Olsson S, Holan C, Montorfano L, Mubang R, Givechian K, Boctor M, Pekarev M, Martinez-Jorge J, Slater E. Complication Profiles of Smooth vs Textured Tissue Expanders in Breast Reconstruction: A Systematic Review and Meta-Analysis. Aesthetic Surgery Journal 2023, 44: 383-393. PMID: 37757895, DOI: 10.1093/asj/sjad319.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus StatementsTranexamic acid in burn surgery: A systematic review and meta-analysis
Fijany A, Givechian K, Zago I, Olsson S, Boctor M, Gandhi R, Pekarev M. Tranexamic acid in burn surgery: A systematic review and meta-analysis. Burns 2023, 49: 1249-1259. PMID: 37268542, DOI: 10.1016/j.burns.2023.05.009.Peer-Reviewed Reviews, Practice Guidelines, Standards, and Consensus Statements
2022
Transformer-based protein generation with regularized latent space optimization
Castro E, Godavarthi A, Rubinfien J, Givechian K, Bhaskar D, Krishnaswamy S. Transformer-based protein generation with regularized latent space optimization. Nature Machine Intelligence 2022, 4: 840-851. DOI: 10.1038/s42256-022-00532-1.Peer-Reviewed Original ResearchMultimodal analysis suggests differential immuno-metabolic crosstalk in lung squamous cell carcinoma and adenocarcinoma
Givechian KB, Ospanova S, Beisenbayeva A, Politi K, Perry RJ. Multimodal analysis suggests differential immuno-metabolic crosstalk in lung squamous cell carcinoma and adenocarcinoma. Npj Precision Oncology 2022, 6: 8. PMID: 35087143, PMCID: PMC8795406, DOI: 10.1038/s41698-021-00248-2.Peer-Reviewed Original Research
2020
Glycolytic expression in lower-grade glioma reveals an epigenetic association between IDH mutation status and PDL1/2 expression
Givechian K, Garner C, Benz S, Rabizadeh S, Soon-Shiong P. Glycolytic expression in lower-grade glioma reveals an epigenetic association between IDH mutation status and PDL1/2 expression. Neuro-Oncology Advances 2020, 3: vdaa162. PMID: 33532725, PMCID: PMC7837356, DOI: 10.1093/noajnl/vdaa162.Peer-Reviewed Original Research
2019
Deep Learning Implicitly Handles Tissue Specific Phenomena to Predict Tumor DNA Accessibility and Immune Activity
Wnuk K, Sudol J, Givechian K, Soon-Shiong P, Rabizadeh S, Szeto C, Vaske C. Deep Learning Implicitly Handles Tissue Specific Phenomena to Predict Tumor DNA Accessibility and Immune Activity. IScience 2019, 20: 119-136. PMID: 31563852, PMCID: PMC6823659, DOI: 10.1016/j.isci.2019.09.018.Peer-Reviewed Original ResearchAn immunogenic NSCLC microenvironment is associated with favorable survival in lung adenocarcinoma
Givechian KB, Garner C, Benz S, Song B, Rabizadeh S, Soon-Shiong P. An immunogenic NSCLC microenvironment is associated with favorable survival in lung adenocarcinoma. Oncotarget 2019, 10: 1840-1849. PMID: 30956762, PMCID: PMC6442995, DOI: 10.18632/oncotarget.26748.Peer-Reviewed Original Research