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Irene Chernova, MD, PhD

Assistant Professor of Medicine (Nephrology)
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Assistant Professor of Medicine (Nephrology)

Biography

Irene Chernova, MD, PhD is an Assistant Professor in the Department of Medicine who's studying the role of B cells in lupus nephritis in the Craft laboratory. Dr. Chernova received her MD and PhD in Immunology at the University of Pennsylvania and then completed her Internal Medicine and Nephrology fellowship training at Yale New Haven Hospital. The Craft lab allowed her to combine her interest in clinical kidney disease and love of kidney physiology with her training in Immunobiology and tackle questions regarding immune cells survival in the inflamed kidney. Specifically, Dr. Chernova is interested in how the unique ionic environment of the kidney influences the survival and function of infiltrating lymphocytes as well as broader questions concerning ion-immune cell interactions which she hopes will form the foundation of her independent laboratory.

Last Updated on July 12, 2023.

Appointments

Other Departments & Organizations

Education & Training

PhD
University of Pennsylvania Perelman School of Medicine (2015)
MD
University of Pennsylvania Perelman School of Medicine (2015)

Research

Research at a Glance

Yale Co-Authors

Frequent collaborators of Irene Chernova's published research.

Publications

Featured Publications

2026

  • APOL1-risk alleles modulate T-cell receptor signaling to promote allograft rejection
    Pell J, Tanvir E, Sun Z, Chernova I, Reghuvaran A, Nagata S, Guerra M, Choi J, Al Chaar S, Mizuno H, Dong K, Tian X, Ishibe R, Franchin B, Cravedi P, Kumar A, Barsotti G, Shi H, De Kumar B, Smithson S, Song W, He J, Chong A, Pober J, Somlo S, Gibson I, Popik W, Zhang Z, Craft J, Azzi J, Murakami N, Ishibe S, Heeger P, Menon M. APOL1-risk alleles modulate T-cell receptor signaling to promote allograft rejection. Journal Of Clinical Investigation 2026 PMID: 42262888, DOI: 10.1172/jci193173.
    Peer-Reviewed Original Research
  • Dehydration promotes intracellular lipid synthesis and accumulation
    Carty J, Selvasingh J, Zuchowski Y, Nam H, PĂ©nalva C, Nanayakkara G, Jennings E, Voss K, Adame E, Tossberg J, Yap W, Melzer M, Viquez O, McCall A, Piotrowski E, Bessho R, Cao S, Leaptrot K, Schrimpe-Rutledge A, Codreanu S, Sherrod S, McLean J, Trapani J, Cottam M, Wan M, Shrivastava D, Delker D, Wilson M, Hasenour C, Lantier L, Chernova I, Young J, Haase V, Vazquez-Medina J, Kosma D, Kim P, Cartailler J, Zhang M, Zent R, Harris R, Watts J, Terker A, Bock F, Rathmell J, Rodan A, Arroyo J. Dehydration promotes intracellular lipid synthesis and accumulation. Nature Communications 2026 PMID: 42185304, DOI: 10.1038/s41467-026-73534-x.
    Peer-Reviewed Original Research

2024

2023

2022

2021

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Academic Achievements & Community Involvement

Honors

  • honor

    Iva Dostanic, MD, PhD, Physician-Scientist Trainee Award

    05/12/2023Yale School of Medicine AwardYale Department of Internal Medicine

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