David P. Kuwayama, MD, MPA, MPhil
Associate Professor of Surgery ( Vascular)Cards
About
Research
Publications
2024
Disease-specific patient-reported quality of life after fenestrated/branched endovascular aortic aneurysm repair
Hoel A, Nayak T, Ponukumati A, Mansukhani N, Stone D, Kuwayama D, Nolan B, Suckow B. Disease-specific patient-reported quality of life after fenestrated/branched endovascular aortic aneurysm repair. Journal Of Vascular Surgery 2024, 81: 280-286.e3. PMID: 39303865, DOI: 10.1016/j.jvs.2024.09.012.Peer-Reviewed Original ResearchMeSH KeywordsAgedAged, 80 and overAortic Aneurysm, AbdominalAortic Aneurysm, ThoracicBlood Vessel ProsthesisBlood Vessel Prosthesis ImplantationDatabases, FactualEndovascular ProceduresFemaleHumansMaleMiddle AgedPatient Reported Outcome MeasuresProsthesis DesignQuality of LifeTime FactorsTreatment OutcomeConceptsPatient-reported quality of lifeF/B-EVARAortic aneurysmPatient-reported qualityQuality of lifeAneurysm repairInfrarenal abdominal aortic aneurysmEndovascular aortic aneurysm repairPost-procedural anxietyProspectively maintained databaseThoracoabdominal aortic aneurysmsComplex aortic diseaseAortic aneurysm repairInfrarenal aneurysm repairComplex aortic aneurysmsDisease-specific QOL surveysPost-procedural changesAbdominal aortic aneurysmPost-operative intervalsDisease-specific quality of lifeAssociated with decreased activityAortic diseasePost-procedureEligible patientsEndovascular technologyLaser assisted trans-endograft coil embolization of a type II endoleak
Mehta K, Ponukumati A, Jacobs B, Kuwayama D. Laser assisted trans-endograft coil embolization of a type II endoleak. Journal Of Vascular Surgery Cases And Innovative Techniques 2024, 10: 101442. PMID: 38510092, PMCID: PMC10951537, DOI: 10.1016/j.jvscit.2024.101442.Peer-Reviewed Original Research
2023
The financial burden associated with endovascular repair of thoracoabdominal and pararenal aortic aneurysms using physician-modified fenestrated-branched endografts
Ilyas S, Stone D, Powell R, Ponukumati A, Kuwayama D, Goodney P, Columbo J, Suckow B. The financial burden associated with endovascular repair of thoracoabdominal and pararenal aortic aneurysms using physician-modified fenestrated-branched endografts. Journal Of Vascular Surgery 2023, 78: 1369-1375. PMID: 37390850, DOI: 10.1016/j.jvs.2023.06.020.Peer-Reviewed Original ResearchConceptsMedian hospital lengthFB-EVARAortic aneurysmAneurysm repairInclusion criteriaQuaternary referral institutionTechnical reimbursementPararenal aortic aneurysmsAortic aneurysm repairMedian hospital length-of-stayHospital length of stayInfrarenal aneurysm repairStudy periodProfessional costsLength of stayNegative marginsEndovascular repairDiagnosis-related group codesNegative operating marginsAneurysm sizeReferral institutionClinical trialsAneurysmPatientsIndex operation
2022
False Lumen Intercostal Artery Embolization to Halt Type R Entry Flow in Chronic Type B Aortic Dissection
Yi J, Magee G, Potter H, Kuwayama D. False Lumen Intercostal Artery Embolization to Halt Type R Entry Flow in Chronic Type B Aortic Dissection. Annals Of Vascular Surgery 2022, 88: 1-8. PMID: 36055458, DOI: 10.1016/j.avsg.2022.07.023.Peer-Reviewed Original ResearchConceptsThoracic endovascular aortic repairType B aortic dissectionSpinal cord ischemiaFalse lumen thrombosisB aortic dissectionChronic type B aortic dissectionEndovascular aortic repairAortic repairCases of spinal cord ischemiaFalse lumenPostoperative computed tomographic angiogramsAssociated with late complicationsMedian air kermaMedian contrast doseCerebrospinal fluid leakMulticenter retrospective reviewProcedure-related morbidityPatent false lumenPerioperative clinical outcomesMedian procedure timeComplex aortic aneurysmsComputed tomographic angiogramDrain-related complicationsSpinal hematomaCord ischemiaUse of real-world data and clinical registries to identify new uses of existing vascular endografts: combined use of GORE EXCLUDER Iliac Branch Endoprosthesis and GORE VIABAHN VBX Balloon Expandable Endoprosthesis
Barnes J, Eid M, Moore K, Aryal S, Gebre E, Woodard J, Kitpanit N, Mao J, Kuwayama D, Suckow B, Schneider D, Abushaikha T, Zusterzeel R, Vemulapalli S, Shenkman E, Williams J, Sedrakyan A, Goodney P. Use of real-world data and clinical registries to identify new uses of existing vascular endografts: combined use of GORE EXCLUDER Iliac Branch Endoprosthesis and GORE VIABAHN VBX Balloon Expandable Endoprosthesis. BMJ Surgery Interventions & Health Technologies 2022, 4: e000085. PMID: 35989872, PMCID: PMC9345049, DOI: 10.1136/bmjsit-2021-000085.Peer-Reviewed Original ResearchGore Viabahn VBX balloon-expandable endoprosthesisGORE EXCLUDER Iliac Branch EndoprosthesisIliac Branch EndoprosthesisIntensive care admissionIntensive care unitBranch EndoprosthesisSurgical exposureNational quality improvement registryOutcome measuresExpandable endoprosthesisShort-term outcome analysisMedian total LOSReal-world evidenceQuality improvement registryIntensive care unit LOSPostoperative myocardial infarctionQuaternary health systemTertiary academic medical centreAccess site complicationsAcademic medical centreDischarged to homeClinical Research NetworkNursing homesPerioperative deathsPostoperative complications
2021
Procedure-Associated Costs and Mid-Term Outcomes of Endovascular Zone 0 and Zone 1 Aortic Arch Repair
Barnes J, Wanken Z, Columbo J, Kuwayama D, Fillinger M, Suckow B. Procedure-Associated Costs and Mid-Term Outcomes of Endovascular Zone 0 and Zone 1 Aortic Arch Repair. Annals Of Vascular Surgery 2021, 81: 98-104. PMID: 34780945, DOI: 10.1016/j.avsg.2021.10.026.Peer-Reviewed Original ResearchConceptsThoracic endovascular aortic repairMid-term outcomesOpen arch reconstructionArch reconstructionStent graftZone 0In situ laser fenestrationDuration of follow-upLess-invasive treatment optionAortic arch pathologiesProximal aortic archEndovascular aortic repairExtra-anatomic bypassHigh-risk patientsRetrospective chart reviewBranch stent graftTertiary medical centerBranch vessel patencyHospital finance departmentArch repairArch pathologiesAortic repairAsymptomatic patientsOpen repairThoracic endograft
2020
Balloon guidance for superior mesenteric artery scallop alignment during Cook Zenith Fenestrated AAA Endovascular Graft deployment
Kuwayama D, Zacharias N. Balloon guidance for superior mesenteric artery scallop alignment during Cook Zenith Fenestrated AAA Endovascular Graft deployment. Journal Of Vascular Surgery Cases And Innovative Techniques 2020, 6: 405-408. PMID: 32715180, PMCID: PMC7369526, DOI: 10.1016/j.jvscit.2020.05.014.Peer-Reviewed Original ResearchAtypical May-Thurner syndrome caused by endovascular aortic aneurysm repair
Yi J, Hadley J, Kuwayama D. Atypical May-Thurner syndrome caused by endovascular aortic aneurysm repair. Journal Of Vascular Surgery Cases And Innovative Techniques 2020, 6: 397-400. PMID: 32715178, PMCID: PMC7369519, DOI: 10.1016/j.jvscit.2020.06.004.Peer-Reviewed Original ResearchMay-Thurner syndromeMay-ThurnerAneurysm repairIliac veinIliac arteryLower extremity venous hypertensionEndovascular aortic aneurysm repairRight common iliac arteryIliac vein thrombosisAortic aneurysm repairCommon iliac arteryEndovascular aneurysm repairIliac artery stentingIliac artery compressionVein thrombosisLumbar spineVenous hypertensionUnusual caseArtery compressionArtery stentingIliacSyndromeArteryVeinRepairNovel use of the ENROUTE transcarotid arterial sheath for antegrade cerebral perfusion during retrograde innominate stenting
Barnes J, Columbo J, Kuwayama D. Novel use of the ENROUTE transcarotid arterial sheath for antegrade cerebral perfusion during retrograde innominate stenting. Journal Of Vascular Surgery Cases And Innovative Techniques 2020, 6: 401-404. PMID: 32715179, PMCID: PMC7369531, DOI: 10.1016/j.jvscit.2020.06.008.Peer-Reviewed Original ResearchIntercostal artery embolization to induce false lumen thrombosis in type B aortic dissection
Magee G, Yi J, Kuwayama D. Intercostal artery embolization to induce false lumen thrombosis in type B aortic dissection. Journal Of Vascular Surgery Cases And Innovative Techniques 2020, 6: 433-437. PMID: 32775849, PMCID: PMC7396825, DOI: 10.1016/j.jvscit.2020.05.012.Peer-Reviewed Original ResearchThoracic endovascular aortic repairType B aortic dissectionB aortic dissectionFalse lumen thrombosisLumen thrombosisArtery embolizationChronic type B aortic dissectionThoracic false lumen thrombosisCone-beam computed tomography angiographyThoracic endovascular aortic repair of type B aortic dissectionFavorable aortic remodelingProgressive aortic enlargementPersistent false lumen flowMaximal aortic diameterFalse lumen flowComputed tomography angiographyAortic enlargementAortic remodelingPostoperative imagingAortic diameterTechnical successAneurysmal degenerationFalse lumenEndovascular toolsThrombosis
Clinical Care
Overview
David Kuwayama, MD, MPA, is the director of Aortic Surgery in the Division of Vascular and Endovascular Surgery. He specializes in novel and minimally invasive treatments for aortic disease, including aneurysms and dissections.
“Aortic surgery has evolved to focus on minimally invasive technologies, ideally to fix aneurysms before they rupture,” Dr. Kuwayama says. “With new techniques, we can treat extensive, complex aneurysms that, previously, were only fixable with major invasive operations.”
One such technique, in which Dr. Kuwayama specializes, is a procedure called fenestrated aortic endografting. During this minimally invasive procedure, a tube-shaped graft (made of fabric supported by metal stents) is custom modified for a patient’s unique aortic anatomy, fixing the aneurysm while also maintaining blood flow where it is needed.
Through an Investigational Device Exemption (IDE) from the U.S. Food and Drug Administration (FDA), Dr. Kuwayama is one of a handful of physicians in the country authorized to custom-build fenestrated endografts. “This technology has been a game-changer. It allows us to fix very challenging aneurysms that wouldn’t have been considered fixable in the past, often with just needle pokes,” he says.
In his aortic role, Dr. Kuwayama collaborates closely with colleagues from other disciplines at Yale, including cardiothoracic surgeons and cardiologists. “Bringing together a multidisciplinary team, we can really ensure that all the brightest minds at Yale are working together to do the best thing for each of our patients. It’s the right way–and the only way–to do it,” he says.
Growing up as the son of a pediatrician, Dr. Kuwayama always knew he wanted to become a physician. “I wanted to follow in the footsteps of my father, who inspired me,” he says. “But I was drawn to surgery because the idea of repairing the human body totally fascinated me.”
As a resident at Johns Hopkins, Dr. Kuwayama first planned to become a trauma surgeon, to help people in their moment of greatest need. “But I quickly learned that the most dangerous injuries were the vascular ones. Stopping the bleeding was always the top priority,” he says. His career path switched. “When an aorta ruptures, it can be just like a gunshot wound. Working quickly and confidently can make all the difference.”
Clinical Specialties
Fact Sheets
Vascular Surgery
Learn More on Yale MedicineEndovascular Debranching Aortic Repair for Thoracoabdominal Aortic Aneurysms
Learn More on Yale Medicine
Board Certifications
Vascular Surgery
- Certification Organization
- AB of Surgery
- Original Certification Date
- 2014
Surgery General
- Certification Organization
- AB of Surgery
- Original Certification Date
- 2010
Yale Medicine News
News & Links
News
- May 14, 2026
Kuwayama Appointed Vascular Director of Yale Aortic Institute
- December 18, 2025
Yale Surgery Team Marks Milestone with 100th Complex Endovascular Aortic Repair
- August 19, 2024
Yale Surgeons Perform Connecticut’s First FDA-Approved TAMBE Procedure, Pioneering Minimally Invasive Aortic Aneurysm Treatment
- May 09, 2023
Dr. David Kuwayama to Lead Yale Vascular Division’s Complex Aortic Surgery Program
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Yale School of Medicine
330 Cedar Street, Boardman 204
New Haven, CT 06511
United States
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Everyone Prashanth Vallabhajosyula, MD, MS - David P. Kuwayama, MD, MPA, MPhil - John Elefteriades, MD - Sandip Mukherjee, MD, FACC