2025
A Case of Persistent, Delayed Multisystem Toxicities After Anti-PD-1 Therapy
Goodman R, Burnette H, Johnson D. A Case of Persistent, Delayed Multisystem Toxicities After Anti-PD-1 Therapy. 2025, 449-454. DOI: 10.1007/978-3-031-83533-9_56.Peer-Reviewed Original ResearchGastroesophageal Intussusception Treated With Combined Transoral Incisionless Fundoplication in a Patient With Systemic Sclerosis
Memon A, Dugan N, Muniraj T, Hinchcliff M, Masoud A. Gastroesophageal Intussusception Treated With Combined Transoral Incisionless Fundoplication in a Patient With Systemic Sclerosis. ACG Case Reports Journal 2025, 12: e01632. PMID: 40196291, PMCID: PMC11975402, DOI: 10.14309/crj.0000000000001632.Peer-Reviewed Original ResearchTransoral incisionless fundoplicationSystemic sclerosisDiffuse cutaneous systemic sclerosisRefractory gastroesophageal reflux diseaseLaparoscopic hiatal hernia repairEvaluation of gastrointestinal symptomsCutaneous systemic sclerosisEsophageal stent placementHiatal hernia repairGastroesophageal reflux diseaseMultidisciplinary team care approachTeam care approachSSc patientsPersistent dysphagiaStent placementGastrointestinal symptomsHernia repairReflux diseaseDiagnostic evaluationDysphagiaPatientsSolid foodSevere symptomsIntussusceptionFundoplicationSafety and Efficacy of Fecal Microbiota, Live-jslm (REBYOTA®), for the Prevention of Recurrent Clostridioides difficile Infection in Participants With Inflammatory Bowel Disease in PUNCH CD3-OLS
Allegretti J, Feuerstadt P, Knapple W, Orenstein R, Pinton P, Sheh A, Khanna S. Safety and Efficacy of Fecal Microbiota, Live-jslm (REBYOTA®), for the Prevention of Recurrent Clostridioides difficile Infection in Participants With Inflammatory Bowel Disease in PUNCH CD3-OLS. Inflammatory Bowel Diseases 2025, izae291. PMID: 39862395, DOI: 10.1093/ibd/izae291.Peer-Reviewed Original ResearchTreatment-emergent adverse eventsRecurrent Clostridioides difficile infectionInflammatory bowel diseaseClostridioides difficile infectionWeeks of administrationPrevention of recurrent CDISerious treatment-emergent adverse eventsSubgroup analysisSustained clinical response ratesBowel diseaseSustained clinical responseClinical response rateModerate gastrointestinal symptomsUS Food and Drug AdministrationTreatment success rateFood and Drug AdministrationClinical responseSingle-doseProspective trialsFecal microbiotaEfficacy outcomesDifficile infectionAdverse eventsGastrointestinal symptomsTreatment success
2024
Impact of Food Avoidance on Vitamin D Intake in Inflammatory Bowel Disease Patients
Almahmoud E, Larson D, Gaidos J, Feagins L, Burgermaster M. Impact of Food Avoidance on Vitamin D Intake in Inflammatory Bowel Disease Patients. Journal Of Nutrition Education And Behavior 2024, 56: s62-s63. DOI: 10.1016/j.jneb.2024.05.144.Peer-Reviewed Original ResearchVitamin D intakeAssociated with vitamin D intakeInflammatory bowel diseaseD intakeInflammatory bowel disease patientsFlare-upVitamin DIntake of vitamin DCross-sectional studyFood avoidanceVitamin D. Vitamin D deficiencyInflammatory bowel disease centerChronic inflammatory diseaseDiet recallMeans foodStudy designAcademic hospitalD deficiencyDisease activityGastrointestinal symptomsInflammatory diseasesParticipantsBowel diseaseDietary restrictionDisease patientsPost–Acute Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) After Infection During Pregnancy
Metz T, Reeder H, Clifton R, Flaherman V, Aragon L, Baucom L, Beamon C, Braverman A, Brown J, Cao T, Chang A, Costantine M, Dionne J, Gibson K, Gross R, Guerreros E, Habli M, Hadlock J, Han J, Hess R, Hillier L, Hoffman M, Hoffman M, Hughes B, Jia X, Kale M, Katz S, Laleau V, Mallett G, Mehari A, Mendez-Figueroa H, McComsey G, Monteiro J, Monzon V, Okumura M, Pant D, Pacheco L, Palatnik A, Palomares K, Parry S, Pettker C, Plunkett B, Poppas A, Ramsey P, Reddy U, Rouse D, Saade G, Sandoval G, Sciurba F, Simhan H, Skupski D, Sowles A, Thorp J, Tita A, Wiegand S, Weiner S, Yee L, Horwitz L, Foulkes A, Jacoby V. Post–Acute Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) After Infection During Pregnancy. Obstetrics And Gynecology 2024, 144: 411-420. PMID: 38991216, PMCID: PMC11326967, DOI: 10.1097/aog.0000000000005670.Peer-Reviewed Original ResearchSARS-CoV-2 infectionSARS-CoV-2Clinical characteristicsSevere acute respiratory syndrome coronavirus 2Gastrointestinal symptomsAcute respiratory syndrome coronavirus 2Respiratory syndrome coronavirus 2Risk factorsPost-acute sequelae of severe acute respiratory syndrome coronavirus 2Syndrome coronavirus 2Acute SARS-CoV-2 infectionHistory of obesityMulticenter cohort studyAssociated with increased prevalenceMultivariate logistic regression modelPostexertional malaiseCoronavirus 2Median timeAcute infection severityLogistic regression modelsAcute infectionCohort studyPredominant symptomPrimary outcomeStudy visits“Deficiency in ELF4, X-Linked”: a Monogenic Disease Entity Resembling Behçet’s Syndrome and Inflammatory Bowel Disease
Olyha S, O’Connor S, Kribis M, Bucklin M, Uthaya Kumar D, Tyler P, Alam F, Jones K, Sheikha H, Konnikova L, Lakhani S, Montgomery R, Catanzaro J, Du H, DiGiacomo D, Rothermel H, Moran C, Fiedler K, Warner N, Hoppenreijs E, van der Made C, Hoischen A, Olbrich P, Neth O, Rodríguez-Martínez A, Lucena Soto J, van Rossum A, Dalm V, Muise A, Lucas C. “Deficiency in ELF4, X-Linked”: a Monogenic Disease Entity Resembling Behçet’s Syndrome and Inflammatory Bowel Disease. Journal Of Clinical Immunology 2024, 44: 44. PMID: 38231408, PMCID: PMC10929603, DOI: 10.1007/s10875-023-01610-8.Peer-Reviewed Original ResearchConceptsDEX patientsClass-switched memory B cellsInborn errors of immunityTreated with anti-inflammatory agentsLow natural killerX-linkedMemory B cellsErrors of immunityCohort of patientsIncreased inflammatory cytokinesLoss-of-function variantsHeterogeneous clinical phenotypesInflammatory bowel diseaseTargeted therapeutic interventionsNatural killerAnti-inflammatory agentsAphthous ulcersTherapeutic responseAutoinflammatory syndromeInflammatory markersClinical manifestationsB cellsBehcet's syndromeGastrointestinal symptomsMechanisms of disease
2023
Thrombotic Microangiopathy and Acute Tubular Injury After Diethylene Glycol Ingestion: A Kidney Biopsy Teaching Case
Malvar G, Gunasekaran D, Mehr N, Ishibe S, Moeckel G. Thrombotic Microangiopathy and Acute Tubular Injury After Diethylene Glycol Ingestion: A Kidney Biopsy Teaching Case. Kidney Medicine 2023, 6: 100758. PMID: 38304581, PMCID: PMC10831151, DOI: 10.1016/j.xkme.2023.100758.Peer-Reviewed Original ResearchAcute tubular injuryThrombotic microangiopathyTubular injuryEndothelial injuryPossible life-threatening complicationsDirect toxic injuryIncidence of AKIInitial gastrointestinal symptomsLife-threatening complicationsTypical clinical courseDiethylene glycol poisoningPeripheral sensorimotor neuropathyHigh mortality rateDiethylene glycol ingestionGastrointestinal symptomsClinical courseKidney biopsyGlycol ingestionSensorimotor neuropathyGlycol poisoningPathological lesionsToxic injuryGenetic predispositionUnusual caseMortality rate2191. An Assessment of Penicillin Allergy Documentation among Patients undergoing Elective Surgeries and Ambulatory Procedures
Banach D, Zavez K, Schramm C, Zolla M, Baron K, Carter E. 2191. An Assessment of Penicillin Allergy Documentation among Patients undergoing Elective Surgeries and Ambulatory Procedures. Open Forum Infectious Diseases 2023, 10: ofad500.1813. PMCID: PMC10678576, DOI: 10.1093/ofid/ofad500.1813.Peer-Reviewed Original ResearchPenicillin allergy recordsSymptoms of allergyElective surgeryAmbulatory proceduresPenicillin allergyAllergy recordsAntibiotic prescribingRisk stratificationMedical assistantsPost-operative adverse eventsPenicillin allergy historyRetrospective chart reviewPenicillin class antibioticsFuture antibiotic prescribingAllergy assessmentGastrointestinal symptomsAdverse eventsChart reviewAllergy historyAllergy documentationCommon symptomsAllergySurgeryPatient reactionsPatientsThe Clinical Utility of Antroduodenal Manometry in the Evaluation of Children with Upper Gastrointestinal Symptoms
Arbizu R, Trauernicht S, Pinillos S, Nurko S, Rodriguez L. The Clinical Utility of Antroduodenal Manometry in the Evaluation of Children with Upper Gastrointestinal Symptoms. Journal Of Pediatric Gastroenterology And Nutrition 2023, 77: 734-740. PMID: 37756372, DOI: 10.1097/mpg.0000000000003956.Peer-Reviewed Original ResearchConceptsGroup B symptomsUpper gastrointestinal symptomsIdiopathic etiologyB symptomsGastrointestinal symptomsPhase IIITreatment responseInitial successful responseIntestinal phase IIIOverall treatment responseSuccessful treatment responseSmall bowel motilityEvaluation of childrenSuccessful responseManometry measuresUGI symptomsAbdominal distentionAntroduodenal manometryPredominant symptomBowel motilityRetrospective reviewClinical findingsClinical utilitySymptomsEtiologyEfficacy and safety of the dual GIP and GLP-1 receptor agonist tirzepatide for weight loss: a meta-analysis of randomized controlled trials
de Mesquita Y, Pera Calvi I, Reis Marques I, Almeida Cruz S, Padrao E, Carvalho P, da Silva C, Cardoso R, Moura F, Rafalskiy V. Efficacy and safety of the dual GIP and GLP-1 receptor agonist tirzepatide for weight loss: a meta-analysis of randomized controlled trials. International Journal Of Obesity 2023, 47: 883-892. PMID: 37460681, DOI: 10.1038/s41366-023-01337-x.Peer-Reviewed Original ResearchConceptsMean differenceRandomized Controlled TrialsOdds ratioGlucagon-like peptide-1 receptor agonistsMeta-analysis of randomized controlled trialsPeptide-1 receptor agonistsControlled TrialsMeta-analysisCo-primary endpointsMethodsWe searched PubMedType 2 diabetesAgonist tirzepatideRisk of biasReview Manager 5.4.1Receptor agonistsReduced BMITherapeutic optionsWaist circumferenceAdverse eventsTirzepatideGastrointestinal symptomsPooled analysisGLP-1PlaceboWeight managementDevelopment of a Definition of Postacute Sequelae of SARS-CoV-2 Infection
Thaweethai T, Jolley S, Karlson E, Levitan E, Levy B, McComsey G, McCorkell L, Nadkarni G, Parthasarathy S, Singh U, Walker T, Selvaggi C, Shinnick D, Schulte C, Atchley-Challenner R, Horwitz L, Foulkes A, Aberg J, Adolphi N, Ahirwar S, Ahmed S, Ahuja N, Aikawa M, Akerlundh A, Akintonwa T, Al-Jadiri A, Alekhina N, Algren H, Alshawabkeh A, Ammar N, Anand A, Anderson B, Aponte-Soto L, Aschner J, Atha M, Atz A, Aupperle R, Ayache M, Azziz-Baumgartner E, Bailey L, Baker F, Balaraman V, Bandy J, Banerjee D, Barch D, Bardes J, Barlocker J, Barr R, Baskin-Sommers A, Basu S, Battaglia T, Baucom L, Beamon C, Beaty C, Beckmann N, Berry J, Bhadelia N, Bhargava D, Bhuiyan S, Bian J, Bime C, Bjork J, Black L, Blish C, Block J, Bogie A, Bolliger D, Bonaventura W, Bose-Brill S, Bower M, Boyd A, Boyineni J, Bradfute S, Bramante C, Brannock M, Bremner J, Brosnahan S, Buchbinder N, Bueler E, Buhimschi I, Bukulmez H, Bunnell H, Buse J, Calhoun E, Cao T, Carrithers M, Carton T, Case A, Casey B, Casimero F, Castro L, Cato T, Ceger P, Cerullo C, Chang L, Chang A, Chebrolu P, Chen Y, Chen L, Chen B, Chestek D, Chew R, Chisolm D, Chow D, Chrisant M, Christakis D, Chute C, Cicek M, Clark C, Clark D, Clarke G, Clouser K, Connors T, Cook J, Coombs K, Cordon-Cardo C, Costello J, Cottrell L, Cowan K, Cowell L, Cranford S, Cronin J, Cummins M, Curry H, D'Sa V, Dabney S, Daniel C, Dapretto M, Darbar D, Darden P, Dasgupta R, Dasgupta S, Davis Blakley F, Dea K, Deakyne Davies S, Decker L, DeFronzo R, Dehority W, Deitchman A, del Alcazar J, Del Boccio P, del Rio C, Del Rios M, DeLisa J, Deoni S, Diaz M, Dickinson J, Dionne A, Diviak K, Donohue S, Downey M, Dozor A, Dreyer B, Dummer K, Durstenfeld M, Dworkin M, Edmonds S, Elias M, Elifritz J, Ellingworth E, Elliott A, Ellison A, Enger M, Espinosa J, Esquenazi-Karonika S, Evans M, Evans D, Facelli J, Fang C, Faustino E, Fayad Lara M, Feldman C, Fiks A, Fineman R, Finn A, Fischer M, Fitzgerald M, Flaherman V, Flotte T, Forsha D, Fortune M, Foxe J, Franks N, Freedman M, Freeland C, Friedman N, Fry G, Gage Witvliet M, Gallagher E, Gallagher R, Garavan H, Gaur S, Gee D, Gennaro M, Gerald L, Ghosh S, Giacino J, Girvin A, Godfrey S, Goldberg M, Goodman S, Gordon H, Gouripeddi R, Graham P, Granger J, Gray K, Greimes T, Gross R, Guthe N, Gutter E, Haasnoot S, Hadley E, Haendel M, Hafner S, Halabi K, Hanley P, Harahsheh A, Harkins M, Hartwig K, Hasbani K, Hasek S, Hauser K, Heath A, Hebson C, Heitzeg M, Hendrickson M, Henrich T, Hernandez-Romieu A, Hester C, Higginbotham M, Hill S, Hirabayashi K, Ho O, Hobart-Porter L, Hoffman M, Holtcamp M, Hong T, Horne B, Horowitz C, Hsia D, Hsu H, Hsue P, Huentelman M, Huerta B, Huling J, Hummel K, Iacono W, Ibanez A, Ibeawuchi C, Irby K, Ismail N, Jacobus J, Jacoby V, Jason L, Javia V, Jennette K, Jernigan T, Jiang S, Jing N, Johnny J, Johnson N, Johnson B, Johnson B, Jone P, Judd S, Juskowich J, Kabagambe E, Kaelber D, Kanjilal D, Kansal M, Kasmarcak T, Kaufman D, Kawakami R, Kellogg D, Kent D, Kewlani D, Khullar D, Kim K, Kim A, Kinser P, Kleinman L, Klerman E, Kluko M, Knight S, Kobayashi M, Kopp K, Koropsak M, Kosut J, Kraig E, Krausert A, Krieger A, Krishna H, Krishnamoorthy A, Krishnan S, Lahs J, Laird A, Laleau V, Lamendola-Essel M, Landeo-Gutierrez J, Lang S, Larson C, Lash J, Lasky-Su J, Laynor G, Lee S, Lee G, Lee F, Lee M, Leese P, Lefebvre R, Levreault A, Lewis K, Li L, Lim P, Lin J, Lisdahl K, Litvack M, Liu X, Lloyd J, Logue J, Loomba J, Lorman V, Lu Y, Ludwig K, Lutz A, Mack J, Mahmoud A, Maier C, Malakooti S, Malchenko S, Mallett G, Maranga G, Martel M, Martin-Herz S, Martinez-Lage M, Maughan C, Mauntel-Medici C, May H, Mayer K, Mazzotti D, McCallum C, McCrindle B, McCulloh R, McDonald D, McInnis S, McMurry J, Mejias A, Melamed J, Menchaca M, Mendelsohn A, Miele L, Miglis M, Milne C, Milner J, Mitchell R, Mittleman M, Mohandas S, Monteiro J, Monzon V, Moreno D, Morgan L, Morozyuk D, Morse K, Moyneur E, Mudumbi P, Müller-Oehring E, Muramatsu N, Musick H, Nagavedu K, Nahin E, Nambiar A, Natelson B, Neale M, Ness-Cochinwala M, Newburger J, Newman L, Nguyen A, Nichols L, Nolan S, Noland S, Novak R, O'Connor G, O'Keefe J, Ogbogu P, Oliveira C, Oster M, Padera R, Paik H, Pajor N, Pan H, Pant D, Partridge A, Patel P, Patel S, Patel K, Paulus M, Payne R, Pearman A, Peralta-Carcelen M, Perez N, Pfaff E, Pillers D, Pitsch C, Pliskin N, Portman M, Postelnicu R, Potter J, Prabhakar B, Prahalad P, Prasad B, Predki B, Preiss A, Prendergast H, Quinn D, Quintana Y, Rabideau D, Radosta J, Radwell J, Raissy H, Ramchandran R, Randall I, Rao S, Rapkiewicz A, Rasmussen S, Razzaghi H, Rebello C, Rebolledo P, Reddy N, Reddy U, Reedy C, Rehman J, Reichard R, Reid K, Reusch J, Rhee K, Rice M, Rizzo J, Roan N, Robarts P, Roberts T, Rochez N, Rodgers K, Rogerson C, Romero M, Rosas J, Rosenzweig E, Rothman R, Rouphael N, Russell M, Rutherfoord M, Sabati A, Sader S, Salehi M, Salisbury A, Sampson B, Sanil Y, Sato A, Saydah S, Schechter M, Schenck E, Schlepphorst K, Schuchard J, Schuh T, Sculley J, Seifert A, Sekar A, Selvarangan R, Seshadri S, Sesso H, Shah D, Shakti D, Shapiro N, Sharma S, Sharma K, Sharma S, Sharma K, Shaw G, Shemesh E, Shen Y, Shenkman E, Shiau S, Siciliano M, Simsir A, Smith V, Snowden J, Solomon I, Spikes L, Squeglia L, Srivastava S, St. Jean M, Stapleford K, Stein C, Stevenson M, Stewart de Ramirez S, Stiles L, Stock A, Stockwell M, Stone J, Stratford J, Stürmer T, Subbian V, Sun J, Suthar M, Sylvera A, Systrom D, Szmuszkovicz J, Talavera-Barber M, Tantisira K, Tartt N, Terlinde T, Teufel R, Thacker D, Thakrar M, Thibodeau S, Thomas G, Thomason M, Tong J, Torres R, Traenkner J, Tragus R, Trinity J, Tronieri J, Troxel A, Truong J, Truong D, Tsevat J, Udosen M, Unterberger K, Utz P, Vaccarino V, Vallejos B, Vanden Hoek T, Vangeepuram N, Varma J, Vernon S, Vidal C, Vivensi S, Vohra A, Wagner L, Wang F, Warburton D, Warner M, Watkins R, Watson S, Webb R, Weeks R, Weiner M, Werzberger A, West S, Weyer J, Wheeler J, Wilkins K, Williams N, Williams C, Wimberly E, Winter T, Woller S, Wong R, Wood J, Wood J, Wood M, Wu Q, Xia Y, Xu J, Yang S, Yin H, Yin H, Yoo Y, Young C, Young N, Zang C, Zempsky W, Zhang B, Zhang Y, Zhang D, Zimmerman E, Andrefsky J, Marrazzo J, Dixon J, Gale L, Maholovich P, Sudhindra P, Thompson T, Sheehan E, Parada A, Knowlton K, Anderson J, McIntyre M, McCandless S, Montoya S, Davis D, Spanier E, Wodushek T, Sokol R, Maldonado Y, Jacobson K, Jia X, Scott J, Quintero O, Haddad F, Valantine H, Zamanian R, Pathak D, Boyce J, Facco F, Hankle S, Vargo J, Campbell D, Armstrong D, Mann M, Burrell N, Bartholomew A, Grobman W, Cackovic B, Klopfenstein B, Weigand S, Snow E, Fennig K, Esplin M, Lamb D, Nelsen A, Phipers J, Fischer L, Docter O, Brown J, DeMartino A, Allard D, Miller E, Bousleiman S, Loffredo M, Vanneman A, Beche I, Chan-Akeley R, Pacheco L, DeVolder J, Salazar A, Thibodeaux L, Cornwell J, Nounes A, Sweet E, Pierse A, Desantis B, Gill-Jones P, Hackney D, Chauhan S, Ortiz F, Treadway J, Rugerio J, Clark K, Leatherland M, Timlin S, Grinnan C, Ferrara J, Kominiarek M, Jones D, Reynolds T, Kearns K, Saffian E, Karasti M, Pizzi C, Filipczak A, Long E, Mitchell M, Barrett K, Mullowney C, Macones G, Alba G, Alicic R, Altman N, Anglin K, Argueta U, Ashktorab H, Baslet G, Bassett I, Bateman L, Bedi B, Bhattacharyya S, Bind M, Blomkalns A, Bonilla H, Brim H, Bush P, Castro M, Chan J, Charney A, Chen P, Chibnik L, Chu H, Clifton R, Costantine M, Cribbs S, Davila Nieves S, Deeks S, Duven A, Emery I, Erdmann N, Erlandson K, Ernst K, Farah-Abraham R, Farner C, Feuerriegel E, Fleurimont J, Fonseca V, Franko N, Gainer V, Gander J, Gardner E, Geng L, Gibson K, Go M, Goldman J, Grebe H, Greenway F, Habli M, Hafner J, Han J, Hanson K, Heath J, Hernandez C, Hess R, Hodder S, Hoffman M, Hoover S, Huang B, Hughes B, Jagannathan P, John J, Jordan M, Katz S, Kaufman E, Kelly J, Kelly S, Kemp M, Kirwan J, Klein J, Knox K, Krishnan J, Kumar A, Laiyemo A, Lambert A, Lanca M, Lee-Iannotti J, Logarbo B, Longo M, Luciano C, Lutrick K, Maley J, Mallett G, Marathe J, Marconi V, Marshall G, Martin C, Matusov Y, Mehari A, Mendez-Figueroa H, Mermelstein R, Metz T, Morse R, Mosier J, Mouchati C, Mullington J, Murphy S, Neuman R, Nikolich J, Ofotokun I, Ojemakinde E, Palatnik A, Palomares K, Parimon T, Parry S, Patterson J, Patterson T, Patzer R, Peluso M, Pemu P, Pettker C, Plunkett B, Pogreba-Brown K, Poppas A, Quigley J, Reddy U, Reece R, Reeder H, Reeves W, Reiman E, Rischard F, Rosand J, Rouse D, Ruff A, Saade G, Sandoval G, Santana J, Schlater S, Sciurba F, Shepherd F, Sherif Z, Simhan H, Singer N, Skupski D, Sowles A, Sparks J, Sukhera F, Taylor B, Teunis L, Thomas R, Thorp J, Thuluvath P, Ticotsky A, Tita A, Tuttle K, Urdaneta A, Valdivieso D, VanWagoner T, Vasey A, Verduzco-Gutierrez M, Wallace Z, Ward H, Warren D, Weiner S, Welch S, Whiteheart S, Wiley Z, Wisnivesky J, Yee L, Zisis S. Development of a Definition of Postacute Sequelae of SARS-CoV-2 Infection. JAMA 2023, 329: 1934-1946. PMID: 37278994, PMCID: PMC10214179, DOI: 10.1001/jama.2023.8823.Peer-Reviewed Original ResearchConceptsSARS-CoV-2 infectionCohort studyPostacute sequelaeProspective observational cohort studyAcute symptom onsetObservational cohort studyProspective cohort studyAdjusted odds ratioDays of infectionSelf-reported symptomsSurvey 6 monthsNumber of infectionsBrain fogChest painChronic coughGastrointestinal symptomsSymptom onsetVaccination statusAcute infectionPostexertional malaiseClinical featuresLong COVIDNew symptomsOdds ratioAbnormal movements
2022
Clinical manifestations of EVALI in adolescents before and during the COVID‐19 pandemic
Abdallah B, Lee H, Weerakoon S, Messiah S, Harrell M, Rao D. Clinical manifestations of EVALI in adolescents before and during the COVID‐19 pandemic. Pediatric Pulmonology 2022, 58: 949-958. PMID: 36530031, PMCID: PMC9878061, DOI: 10.1002/ppul.26283.Peer-Reviewed Original ResearchConceptsHome oxygenGastrointestinal symptomsEVALI casesPatients treated with corticosteroidsProduct use-associated lung injuryHospital course of patientsUse-associated lung injuryDischarged with home oxygenSARS-CoV-2 RT-PCR test resultsCourse of patientsE-cigarettesPositive SARS-CoV-2 RT-PCR test resultsPulmonary function improvementReview of adolescentsPulmonary function testsShorter median lengthRT-PCR test resultsClinical presentationClinical improvementClinical characteristicsHospital courseClinical manifestationsLung injuryMechanical ventilationMedian lengthAcute kidney injury due to myoglobin cast nephropathy in the setting of coronavirus disease 2019-mediated rhabdomyolysis: a case report
Tuan J, Ogbuagu O, Kumar D, Altice F, Fikrig M. Acute kidney injury due to myoglobin cast nephropathy in the setting of coronavirus disease 2019-mediated rhabdomyolysis: a case report. Journal Of Medical Case Reports 2022, 16: 491. PMID: 36578087, PMCID: PMC9795945, DOI: 10.1186/s13256-022-03721-z.Peer-Reviewed Case Reports and Technical NotesConceptsAcute kidney injuryCoronavirus disease 2019Kidney injuryDisease 2019Cast nephropathyEnd-organ damageRenal biopsy findingsSpectrum of diseaseBaseline 6Gastrointestinal symptomsHospital courseBiopsy findingsCase presentationAPoor appetiteRenal failureRenal functionOral intakeUrine outputInitial diagnosisCaucasian manCase reportRhabdomyolysisNephropathyAbnormal tasteOrgan systemsDevelopment and Resolution of Secondary Adrenal Insufficiency after an Intra‐Articular Steroid Injection
Tan J, Majumdar S. Development and Resolution of Secondary Adrenal Insufficiency after an Intra‐Articular Steroid Injection. Case Reports In Endocrinology 2022, 2022: 4798466. PMID: 36588627, PMCID: PMC9800097, DOI: 10.1155/2022/4798466.Peer-Reviewed Original ResearchSecondary adrenal insufficiencyIntra-articular steroid injectionHypothalamic-pituitary axisSteroid injectionAdrenal insufficiencyIntra-articular steroidsIatrogenic Cushing's syndromeNonspecific gastrointestinal symptomsLow morning cortisolCorticosteroid usersSystemic corticosteroidsCorticosteroid injectionGastrointestinal symptomsLocal corticosteroidsNonspecific symptomsCushing's syndromeFurther workupInitial diagnosisAdrenal axisHPA responsivenessInflammatory conditionsTendon sheathMorning cortisolLower riskClinical practiceAcute Hepatitis of Unknown Origin in Children: Early Observations from the 2022 Outbreak
Zhang LY, Huang LS, Yue YH, Fawaz R, Lim JK, Fan JG. Acute Hepatitis of Unknown Origin in Children: Early Observations from the 2022 Outbreak. Journal Of Clinical And Translational Hepatology 2022, 10: 522-530. PMID: 35836761, PMCID: PMC9240245, DOI: 10.14218/jcth.2022.00281.Peer-Reviewed Original ResearchAcute hepatitisSevere acute respiratory syndrome coronavirus 2Acute respiratory syndrome coronavirus 2Unknown originRespiratory syndrome coronavirus 2Serum aminotransaminase levelsAcute liver failureIU/LSyndrome coronavirus 2Immune cell activationAminotransaminase levelsGastrointestinal symptomsLiver transplantationLiver failureCoronavirus 2Healthy childrenNegative testCell activationHepatitisCOVID-19 pandemicChildrenRecent reportsEarlier observationsOutbreakCauseClinical characteristics and treatments of multi-system inflammatory syndrome in children: a systematic review.
Lee K, Li H, Lee M, Park S, Kim J, Han Y, Cho K, Ha B, Kim S, Jacob L, Koyanagi A, Shin J, Kim J, Smith L. Clinical characteristics and treatments of multi-system inflammatory syndrome in children: a systematic review. European Review For Medical And Pharmacological Sciences 2022, 26: 3342-3350. PMID: 35587087, DOI: 10.26355/eurrev_202205_28754.Peer-Reviewed Original ResearchConceptsMIS-CSevere COVID-19Kawasaki diseaseInflammatory syndromeDiagnostic criteriaMulti-system inflammatory syndromeAtypical Kawasaki diseaseAge of patientsMultisystem inflammatory syndromeAssociated with coronavirus disease 2019Indicators of inflammationIntravenous immunoglobulinLaboratory characteristicsPresenting symptomsInotropic agentsMIS-C.D-dimerCase seriesClinical characteristicsCardiac injuryGastrointestinal symptomsTroponin IEarly diagnosisIL-6Average ageCOVID-19 Clinical Presentation Among HIV-Infected Persons in China: A Systematic Review
Huang D, Zunong J, Li M, Li D, Gong J, Vermund SH, Hu Y. COVID-19 Clinical Presentation Among HIV-Infected Persons in China: A Systematic Review. Current HIV/AIDS Reports 2022, 19: 167-176. PMID: 35394249, PMCID: PMC8990500, DOI: 10.1007/s11904-022-00606-0.Peer-Reviewed Original ResearchConceptsAntiretroviral therapyCOVID-19 clinical severityCOVID-19 clinical presentationCOVID-19Undetectable viral loadAsymptomatic COVID-19Severe COVID-19Last clinical visitCase series/reportsCase fatality rateCOVID-19 prognosisLate antiretroviral therapyIL-6 resultsSARS-CoV-2COVID-19 diagnosisMedian CD4Gastrointestinal symptomsHIV infectionMedian ageRespiratory distressClinical featuresClinical presentationClinical visitsViral loadClinical detailsSystemic Manifestations of Gastrointestinal Tract Diseases and Systemic Diseases Involving the Gastrointestinal Tract
Patel N, Das P, Jain D. Systemic Manifestations of Gastrointestinal Tract Diseases and Systemic Diseases Involving the Gastrointestinal Tract. 2022, 521-572. DOI: 10.1007/978-981-16-6395-6_14.Peer-Reviewed Original ResearchExtraintestinal manifestationsGastrointestinal disordersSystemic diseaseGastrointestinal tractPrimary gastrointestinal disordersCommon gastrointestinal disorderInflammatory bowel diseaseCommon systemic diseasesGastrointestinal tract diseaseGastrointestinal symptomsBowel diseaseRenal diseaseSystemic manifestationsVasculitic disordersWhipple's diseaseSystemic disordersVascular diseaseCeliac diseaseGastrointestinal infectionsTract diseasePathogenetic mechanismsPolyposis syndromeGastrointestinal diseasesPancreatic diseaseDiseaseOutcomes of COVID-19 in Patients with Inflammatory Bowel Disease: Comparison with Household Members and the Role of IBD Medications
Sima A, Saberzadeh-Ardestani B, Vahedi H, Fakheri H, Mansour-Ghanaei F, Maleki I, Nasseri-Moghaddam S, Vosoghinia H, Ghadir M, Hormati A, Kasaeian A, Radmard A, Khosravi B, Malekzadeh M, Alatab S, Sadeghi A, Aminisani N, Poustchi H, Gonoudi E, Anushiravani A, Rayatpisheh M, Colombel J, Ungaro R, Malekzadeh R. Outcomes of COVID-19 in Patients with Inflammatory Bowel Disease: Comparison with Household Members and the Role of IBD Medications. Archives Of Iranian Medicine 2022, 25: 17-25. PMID: 35128908, DOI: 10.34172/aim.2022.04.Peer-Reviewed Original ResearchConceptsInflammatory bowel disease patientsInflammatory bowel diseaseGastrointestinal symptomsAnti-tumor necrosis factorAssociated with increased hospitalization ratesBowel diseasePresence of inflammatory bowel diseaseAssociated with higher hospitalization ratesCOVID-19 outcomesAssociated with more severe outcomesAnti-TNF therapyInflammatory bowel disease medicationsHospitalization ratesNon-IBD patientsOutcomes of COVID-19Prospective cohort studyMultivariate logistic regressionEffect of inflammatory bowel diseaseCOVID-19 patientsAssociated with hospitalizationNo significant differenceHigher hospitalization ratesClinical characteristicsCohort studyNecrosis factor
2021
Clinical characteristics and prognostic factors of myocarditis associated with the mRNA COVID‐19 vaccine
Woo W, Kim A, Yon D, Lee S, Hwang J, Jacob L, Koyanagi A, Kim M, Moon D, Jung J, Choi J, Jung S, Eun L, Lee S, Shin J, Smith L. Clinical characteristics and prognostic factors of myocarditis associated with the mRNA COVID‐19 vaccine. Journal Of Medical Virology 2021, 94: 1566-1580. PMID: 34862617, PMCID: PMC9015469, DOI: 10.1002/jmv.27501.Peer-Reviewed Original ResearchConceptsGastrointestinal symptomsMRNA-1273Conservative careIntensive careAnalyzed clinical manifestationsMRNA COVID-19 vaccineLeft ventricular dysfunctionProportion of patientsMRNA-1273 vaccineOutcome of myocarditisIntensive care unitInvestigate risk factorsMagnetic resonance imagingRisk factor analysisMRNA-1273 recipientsPrognostic factorsVentricular dysfunctionClinical courseEjection fractionMedian ageClinical presentationMyocardial inflammationCase seriesClinical characteristicsCase report
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