2024
Improving cefazolin administration for surgical prophylaxis in reported penicillin allergy: A retrospective study of a health system intervention
Belmont A, Son M, Hyman J, You L, Su C, Kashyap N, Topal J, McManus D, Martinello R, Kwah J. Improving cefazolin administration for surgical prophylaxis in reported penicillin allergy: A retrospective study of a health system intervention. Journal Of Allergy And Clinical Immunology Global 2024, 4: 100377. PMID: 39830990, PMCID: PMC11742594, DOI: 10.1016/j.jacig.2024.100377.Peer-Reviewed Original ResearchPenicillin allergy labelHospital-wide guidelinesSurgical site infectionAllergy labelsSurgical patientsSevere allergic reactionsSurgical prophylaxisSite infectionAssociated with increased rates of surgical site infectionRate of surgical site infectionMulti-drug resistant infectionsAllergic reactionsPrevent surgical site infectionsFirst-line antibioticsFirst-line prophylaxisAdministration of cefazolinAssociated with increased ratesRetrospective cohort studyGuideline-directed therapyAdult surgical patientsPre-intervention groupPost-intervention groupPenicillin allergyPerioperative outcomesCefazolin administrationDiagnosis and clinical management of drug allergies in obstetrics and gynecology: an expert review
Burn M, Kwah J, Son M. Diagnosis and clinical management of drug allergies in obstetrics and gynecology: an expert review. American Journal Of Obstetrics And Gynecology 2024, 232: 243-261. PMID: 39490659, DOI: 10.1016/j.ajog.2024.10.025.Peer-Reviewed Original ResearchPenicillin allergyAntibiotic allergyAllergy evaluationDrug allergySkin testOral challengePregnant patientsObstetrician-GynecologistsAntibiotic useAssociated with increased cesarean deliveryAllergy testingGroup B streptococcus sepsisPatient historyNeonatal length of stayManagement of drug allergyIncreased length of hospital stayUnverified penicillin allergyLength of hospital stayFirst-line therapyFirst line antibioticsInduction of drug toleranceHigh-risk patientsSurgical site infectionIncreased surgical site infectionAdministration of antibioticsA call to address penicillin allergy labels in patients with hematopoietic stem cell transplants: How to avoid rash decisions
Belmont A, Stone C, Guyer A, Edelman E, Trubiano J. A call to address penicillin allergy labels in patients with hematopoietic stem cell transplants: How to avoid rash decisions. Transplant Infectious Disease 2024, 26: e14350. PMID: 39101669, PMCID: PMC11502247, DOI: 10.1111/tid.14350.Peer-Reviewed Original ResearchHematopoietic stem cell transplantationStem cell transplantationPenicillin allergy labelMultidrug-resistant infectionsPenicillin allergyCell transplantationAllergy labelsAssociated with more severe infectionsReported penicillin allergyRisk-stratify patientsMore severe infectionsPoint-of-care assessmentBeta-lactam antibioticsClinical decision toolTolerate penicillinsAssociated with useDelabel patientsTherapeutic optionsEvaluating patientsSevere infectionsAlternative antibioticsOral challengeClinical care settingsClostridium difficilePatientsThe Cost of Developing and Implementing an Antepartum Referral Program for Penicillin Allergy Evaluation at a Single Academic Tertiary Care Hospital
Burn M, Xu X, Kwah J, Liao J, Son M. The Cost of Developing and Implementing an Antepartum Referral Program for Penicillin Allergy Evaluation at a Single Academic Tertiary Care Hospital. American Journal Of Perinatology 2024, 41: 1290-1297. PMID: 38423122, DOI: 10.1055/a-2278-9279.Peer-Reviewed Original ResearchCost of careReferral programLong-term cost benefitsPenicillin allergyAntibiotic costsAntibiotic stewardshipPregnant individualsProgram developmentAcademic tertiary care hospitalCompare costs of carePenicillin allergy evaluationShort-term costsTertiary care hospitalDelivery hospitalizationsResource utilization dataNo significant differenceNonreferred patientsCare hospitalUtilization dataAllergy evaluationBivariate testsStudy groupEducational initiativesPregnancy periodProgram costs
2023
2191. An Assessment of Penicillin Allergy Documentation among Patients undergoing Elective Surgeries and Ambulatory Procedures
Banach D, Zavez K, Schramm C, Zolla M, Baron K, Carter E. 2191. An Assessment of Penicillin Allergy Documentation among Patients undergoing Elective Surgeries and Ambulatory Procedures. Open Forum Infectious Diseases 2023, 10: ofad500.1813. PMCID: PMC10678576, DOI: 10.1093/ofid/ofad500.1813.Peer-Reviewed Original ResearchPenicillin allergy recordsSymptoms of allergyElective surgeryAmbulatory proceduresPenicillin allergyAllergy recordsAntibiotic prescribingRisk stratificationMedical assistantsPost-operative adverse eventsPenicillin allergy historyRetrospective chart reviewPenicillin class antibioticsFuture antibiotic prescribingAllergy assessmentGastrointestinal symptomsAdverse eventsChart reviewAllergy historyAllergy documentationCommon symptomsAllergySurgeryPatient reactionsPatientsPregnant Patients with a Documented History of Penicillin Allergy and Associated Maternal and Neonatal Outcomes at a Tertiary Care Center
Azmy V, Lundsberg L, Culhane J, Kwah J, Partridge C, Son M. Pregnant Patients with a Documented History of Penicillin Allergy and Associated Maternal and Neonatal Outcomes at a Tertiary Care Center. American Journal Of Perinatology 2023, 41: e2051-e2057. PMID: 37211008, DOI: 10.1055/a-2096-5002.Peer-Reviewed Original ResearchPenicillin allergy historyNon-β-lactam antibioticsPenicillin allergyNeonatal outcomesPregnant patientsAllergy historyPregnant individualsElectronic medical recordsMedical recordsMultivariable analysisPostpartum endometritisHigh riskLactam antibioticsSignificant differencesBad obstetric outcomeRetrospective cohort studyTertiary care centerPostnatal hospital stayWeeks of gestationLarge academic hospitalAssociated maternalEligible deliveriesHospital stayMaternal outcomesObstetric outcomesAntibiotic choice for Group B Streptococcus prophylaxis in mothers with reported penicillin allergy and associated newborn outcomes
Snider J, Mithal L, Kwah J, Rhodes N, Son M. Antibiotic choice for Group B Streptococcus prophylaxis in mothers with reported penicillin allergy and associated newborn outcomes. BMC Pregnancy And Childbirth 2023, 23: 400. PMID: 37254067, PMCID: PMC10228028, DOI: 10.1186/s12884-023-05697-0.Peer-Reviewed Original ResearchConceptsGroup B streptococcus prophylaxisReported penicillin allergyPenicillin allergyGBS prophylaxisLab drawsNeonatal outcomesNewborn outcomesAntibiotic administrationMedical recordsPregnant individualsIntrapartum group B streptococcus prophylaxisNeonatal intensive care unit admissionDesignThis retrospective cohort studyIntensive care unit admissionSelf-reported penicillin allergyNeonates of mothersCare unit admissionIntrapartum antibiotic prophylaxisRetrospective cohort studyWeeks of gestationMother-infant pairsMother-infant dyadsBeta-lactam antibioticsAntibiotic prophylaxisUnit admission
2022
Survey of Obstetric Providers to Assess the Knowledge and Management of a Reported Penicillin Allergy in Pregnant Women
Cate JJM, Burn M, Kwah J, Liao J, Illuzzi J, Reddy U, Son M. Survey of Obstetric Providers to Assess the Knowledge and Management of a Reported Penicillin Allergy in Pregnant Women. American Journal Of Perinatology 2022, 40: 001-008. PMID: 35709740, DOI: 10.1055/a-1877-9970.Peer-Reviewed Original ResearchConceptsPenicillin skin testingReported penicillin allergyPenicillin allergyObstetric providersPractice patternsEducational sessionsAllergy knowledgeProvider knowledgeEducational interventionSingle academic medical centerPenicillin allergy delabelingPenicillin allergy evaluationPenicillin allergy testingPercentage of patientsIdentification of patientsClinical practice patternsSmall group educational sessionsAcademic medical centerChi-square testAllergy evaluationPenicillin allergicPerinatal outcomesPregnant patientsDrug allergyAllergy testingOutpatient penicillin allergy evaluation during pregnancy and associated clinical outcomes
Kwah JH, Burn MS, Liao J, Cate J, Son M. Outpatient penicillin allergy evaluation during pregnancy and associated clinical outcomes. American Journal Of Obstetrics & Gynecology MFM 2022, 4: 100674. PMID: 35691578, DOI: 10.1016/j.ajogmf.2022.100674.Peer-Reviewed Original ResearchConceptsPenicillin allergy evaluationPenicillin allergyPregnant womenAllergy evaluationHospital stayNeonatal outcomesClinical benefitIntensive care unit admissionBirth hospitalization lengthUnverified penicillin allergyCare unit admissionNeonatal adverse outcomesRetrospective cohort studyMedical record reviewPostpartum hospital stayAdditional clinical benefitLarge academic hospitalElectronic medical recordsBeta-lactam antibioticsPostpartum infectionReferred womenUnit admissionMaternal outcomesCohort studyTrue allergy
2009
Continuous-Infusion Oxacillin for the Treatment of Burn Wound Cellulitis
Schuster KM, Wilson D, Schulman CI, Pizano LR, Ward CG, Namias N. Continuous-Infusion Oxacillin for the Treatment of Burn Wound Cellulitis. Surgical Infections 2009, 10: 41-45. PMID: 19245363, DOI: 10.1089/sur.2007.081.Peer-Reviewed Original ResearchConceptsIntravenous vancomycinFever resolutionSuccess rateResolution of leukocytosisLonger treatment coursesBeta-hemolytic streptococciDevelopment of cellulitisGraft donor sitesRegional burn centerTime-dependent killingWound cellulitisPenicillin allergyAntibiotic cessationConcomitant infectionInitial antibioticsTreatment courseBurn centerPhysical findingsSuccessful treatmentAllergic reactionsCellulitisClinical consequencesOxacillin treatmentLeukocytosisPatients
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