2022
Systemic Manifestations of Gastrointestinal Tract Diseases and Systemic Diseases Involving the Gastrointestinal Tract
Patel N, Das P, Jain D. Systemic Manifestations of Gastrointestinal Tract Diseases and Systemic Diseases Involving the Gastrointestinal Tract. 2022, 521-572. DOI: 10.1007/978-981-16-6395-6_14.Peer-Reviewed Original ResearchExtraintestinal manifestationsGastrointestinal disordersSystemic diseaseGastrointestinal tractPrimary gastrointestinal disordersCommon gastrointestinal disorderInflammatory bowel diseaseCommon systemic diseasesGastrointestinal tract diseaseGastrointestinal symptomsBowel diseaseRenal diseaseSystemic manifestationsVasculitic disordersWhipple's diseaseSystemic disordersVascular diseaseCeliac diseaseGastrointestinal infectionsTract diseasePathogenetic mechanismsPolyposis syndromeGastrointestinal diseasesPancreatic diseaseDisease
2021
Targeted therapies: Expanding the role of FGFR3 inhibition in urothelial carcinoma
Zengin Z, Chehrazi-Raffle A, Salgia N, Muddasani R, Ali S, Meza L, Pal S. Targeted therapies: Expanding the role of FGFR3 inhibition in urothelial carcinoma. Urologic Oncology Seminars And Original Investigations 2021, 40: 25-36. PMID: 34840077, DOI: 10.1016/j.urolonc.2021.10.003.Peer-Reviewed Original ResearchConceptsImmune checkpoint inhibitorsUrothelial carcinomaCheckpoint inhibitorsTargeted therapyLower tract diseaseMultiple disease stagesMetastatic urothelial carcinomaOverall response rateAntibody-drug conjugatesGrowth factor receptor familyFGFR3 inhibitionUC tumorsChemotherapy regimensUpper tractOngoing trialsDisease stageTract diseaseTreatment paradigmFactor receptor familyHigh incidenceActionable mutationsFGFR1-4FGFR3 inhibitorsSmall molecule inhibitorsFGFR3 mutationsB Cell Mobilization, Dissemination, Fine Tuning of Local Antigen Specificity and Isotype Selection in Asthma
Ohm-Laursen L, Meng H, Hoehn KB, Nouri N, Jiang Y, Clouser C, Johnstone TG, Hause R, Sandhar BS, Upton NEG, Chevretton EB, Lakhani R, Corrigan CJ, Kleinstein SH, Gould HJ. B Cell Mobilization, Dissemination, Fine Tuning of Local Antigen Specificity and Isotype Selection in Asthma. Frontiers In Immunology 2021, 12: 702074. PMID: 34721376, PMCID: PMC8552043, DOI: 10.3389/fimmu.2021.702074.Peer-Reviewed Original ResearchConceptsLower respiratory tractRespiratory tractB cellsAtopic asthmaPlasma cellsCommon respiratory tract diseaseB-cell mobilizationNon-atopic controlsRespiratory tract mucosaUpper respiratory tractRespiratory tract diseaseOrgan-specific diseasesAntibody repertoireB cell clonesAdaptive immune receptor repertoire sequencingBronchial mucosaNasal mucosaTract diseaseCell mobilizationIsotype selectionAntigen specificityAdult volunteersMucosal surfacesImmune systemAsthmaBile Microbiota in Liver Transplantation: Proof of Concept Using Gene Amplification in a Heterogeneous Clinical Scenario
D'Amico F, Bertacco A, Finotti M, Di Renzo C, Rodriguez-Davalos MI, Gondolesi GE, Cillo U, Mulligan D, Geibel J. Bile Microbiota in Liver Transplantation: Proof of Concept Using Gene Amplification in a Heterogeneous Clinical Scenario. Frontiers In Surgery 2021, 8: 621525. PMID: 33796547, PMCID: PMC8009296, DOI: 10.3389/fsurg.2021.621525.Peer-Reviewed Original ResearchBile microbiotaLiver donorsBiliary tract diseaseCommon bile ductGene amplificationRibosomal RNA gene amplificationLiver recipientsLiver transplantationPediatric recipientsLiver proceduresBiliary tractBile ductRecipient patientsTract diseaseBile samplesHeterogeneous cohortClinical scenariosBileSterile wayPCR sequencingPatientsRecipientsMicrobiotaTransplantationGallbladder
2020
Liver Matrix in Benign and Malignant Biliary Tract Disease
Fabris L, Cadamuro M, Cagnin S, Strazzabosco M, Gores G. Liver Matrix in Benign and Malignant Biliary Tract Disease. Seminars In Liver Disease 2020, 40: 282-297. PMID: 32162285, DOI: 10.1055/s-0040-1705109.Peer-Reviewed Original ResearchConceptsMalignant biliary tract diseasesBiliary tract diseaseExtracellular matrixReactive ductular cellsPro-oncogenic effectsHepatic progenitor cellsExtracellular matrix undergoesBiliary repairDuctular reactionTract diseaseBiliary damageMalignant transformationResident cellsDuctular cellsMain molecular factorsProgenitor cellsMolecular factorsMechanical signalsLiver matrixNoncollagenous glycoproteinsStructural alterationsDirect interactionBiochemical compositionCellsMultifunctional molecules
2017
Minimally Invasive Therapy for Upper Tract Urothelial Cell Cancer
Pan S, Smith AD, Motamedinia P. Minimally Invasive Therapy for Upper Tract Urothelial Cell Cancer. Journal Of Endourology 2017, 31: 238-245. PMID: 28117602, DOI: 10.1089/end.2016.0475.Peer-Reviewed Original Research
2014
9:21 AM Abstract No. 98 Percutaneous transhepatic cholangioscopy: outcome as a diagnostic and therapeutic tool in the management of biliary tract disease
Schlachter T, Hong K, Lessne M, Holly B, Weiss C, Duran R. 9:21 AM Abstract No. 98 Percutaneous transhepatic cholangioscopy: outcome as a diagnostic and therapeutic tool in the management of biliary tract disease. Journal Of Vascular And Interventional Radiology 2014, 25: s50-s51. DOI: 10.1016/j.jvir.2013.12.122.Peer-Reviewed Original Research
2012
Differences in evolution of children with non-severe acute lower respiratory tract infection with and without radiographically diagnosed pneumonia
Fontoura M, Matutino A, Silva C, Santana M, Nobre-Bastos M, Oliveira F, Barreto B, Araújo-Neto C, Andrade S, Brim R, Cardoso M, Nascimento-Carvalho C, Pneumopac-Efficacy Study Group. Differences in evolution of children with non-severe acute lower respiratory tract infection with and without radiographically diagnosed pneumonia. Indian Pediatrics 2012, 49: 363-369. PMID: 22080618, DOI: 10.1007/s13312-012-0085-6.Peer-Reviewed Original ResearchConceptsAcute lower respiratory tract infectionChest X-rayLower respiratory tract infectionsRespiratory tract infectionsTract infectionsLower respiratory tract diseaseEvolution of childrenNormal chest X-rayIndependent pediatric radiologistsHigh positive predictive valueUniversity Pediatric HospitalRespiratory tract diseasePositive predictive valueAmoxicillin allergyPulmonary infiltratesPleural effusionClinical symptomsPediatric hospitalAmoxicillin treatmentResultsA totalPulmonary expansionActive surveillancePneumonia casesTract diseaseAntibiotic use
2009
Rhinoviruses Are a Major Cause of Wheezing and Hospitalization in Children Less Than 2 Years of Age
Piotrowska Z, Vázquez M, Shapiro ED, Weibel C, Ferguson D, Landry ML, Kahn JS. Rhinoviruses Are a Major Cause of Wheezing and Hospitalization in Children Less Than 2 Years of Age. The Pediatric Infectious Disease Journal 2009, 28: 25-29. PMID: 19057454, PMCID: PMC4639321, DOI: 10.1097/inf.0b013e3181861da0.Peer-Reviewed Original ResearchConceptsRespiratory syncytial virusHRV-positive childrenHuman rhinovirusSyncytial virusAge groupsDiagnostic laboratoriesRespiratory tract diseaseMajor respiratory pathogenRate of infectionYears of ageSimilar age groupAsymptomatic childrenRespiratory specimenAsymptomatic groupRespiratory infectionsHRV infectionHospitalization ratesPolymerase chain reactionTract diseaseRespiratory pathogensHRV isolatesMajor causeStudy periodSymptomsInfection
2008
Role of Human Polyomaviruses in Respiratory Tract Disease in Young Children - Volume 14, Number 11—November 2008 - Emerging Infectious Diseases journal - CDC
Wattier RL, Vázquez M, Weibel C, Shapiro ED, Ferguson D, Landry ML, Kahn JS. Role of Human Polyomaviruses in Respiratory Tract Disease in Young Children - Volume 14, Number 11—November 2008 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2008, 14: 1766-1768. PMID: 18976566, PMCID: PMC2630739, DOI: 10.3201/eid1411.080394.Peer-Reviewed Original ResearchHuman Bocavirus: a Newly Discovered Human Parvovirus
Kahn J, Tattersall P. Human Bocavirus: a Newly Discovered Human Parvovirus. 2008, 21-38. DOI: 10.1128/9781555815592.ch2.Peer-Reviewed Original ResearchSevere acute respiratory syndrome-associated coronavirusPopulation-based surveillance studyRespiratory tract infectionsNew respiratory virusesRespiratory viral pathogensCause of morbiditySerum of childrenRespiratory tract diseaseViral pathogensNovel human polyomavirusesHBoV DNATract infectionsRespiratory virusesRespiratory secretionsHuman bocavirusHuman metapneumovirusRespiratory specimensTract diseaseHBoVViral life cycleSurveillance studyHuman polyomavirusesHuman rhinovirusHuman parvovirusPneumoniaAcute Pyelonephritis Caused by Aerococcus urinae in a 12-Year-Old Boy
Murray TS, Muldrew KL, Finkelstein R, Hampton L, Edberg SC, Cappello M. Acute Pyelonephritis Caused by Aerococcus urinae in a 12-Year-Old Boy. The Pediatric Infectious Disease Journal 2008, 27: 760-762. PMID: 18574434, DOI: 10.1097/inf.0b013e318170af46.Peer-Reviewed Case Reports and Technical Notes
2006
Human Bocavirus Infection in Young Children in the United States: Molecular Epidemiological Profile and Clinical Characteristics of a Newly Emerging Respiratory Virus
Kesebir D, Vazquez M, Weibel C, Shapiro ED, Ferguson D, Landry ML, Kahn JS. Human Bocavirus Infection in Young Children in the United States: Molecular Epidemiological Profile and Clinical Characteristics of a Newly Emerging Respiratory Virus. The Journal Of Infectious Diseases 2006, 194: 1276-1282. PMID: 17041854, PMCID: PMC7204143, DOI: 10.1086/508213.Peer-Reviewed Original ResearchConceptsRespiratory tract diseasePolymerase chain reactionAsymptomatic childrenClinical characteristicsEpidemiological profileRespiratory specimensTract diseaseLower respiratory tract diseaseHBoV-positive childrenHuman bocavirus infectionRespiratory syncytial virusMolecular epidemiological profileYears of ageYoung childrenDiagnostic laboratoriesBocavirus infectionRespiratory specimenAbnormal findingsRespiratory virusesRespiratory secretionsSyncytial virusHuman bocavirusParainfluenza virusB virusChest radiographyCoronavirus HKU1 Infection in the United States - Volume 12, Number 5—May 2006 - Emerging Infectious Diseases journal - CDC
Esper F, Weibel C, Ferguson D, Landry ML, Kahn JS. Coronavirus HKU1 Infection in the United States - Volume 12, Number 5—May 2006 - Emerging Infectious Diseases journal - CDC. Emerging Infectious Diseases 2006, 12: 775-779. PMID: 16704837, PMCID: PMC3374449, DOI: 10.3201/eid1205.051316.Peer-Reviewed Original ResearchConceptsHCoV-HKU1Respiratory specimensLower respiratory tract infectionsLower respiratory tract diseaseHCoV-HKU1 infectionRespiratory tract infectionsRespiratory syncytial virusRespiratory tract diseaseReverse transcription-polymerase chain reactionNew human coronavirusYears of ageTranscription-polymerase chain reactionTract infectionsSyncytial virusPositive childrenParainfluenza virusTract diseaseRespiratory tractHuman coronavirusesPositive specimensInfluenza virusInfectionChain reactionChildrenVirus
2005
Evidence of a Novel Human Coronavirus That Is Associated with Respiratory Tract Disease in Infants and Young Children
Esper F, Weibel C, Ferguson D, Landry ML, Kahn JS. Evidence of a Novel Human Coronavirus That Is Associated with Respiratory Tract Disease in Infants and Young Children. The Journal Of Infectious Diseases 2005, 191: 492-498. PMID: 15655770, PMCID: PMC7199485, DOI: 10.1086/428138.Peer-Reviewed Original ResearchConceptsRespiratory tract diseaseTract diseaseNovel human coronavirusHuman coronavirusesYoung childrenNew Haven coronavirusAbnormal breath soundsClinical featuresSymptomatic childrenPolymerase chain reactionRespiratory specimensRespiratory tractCommon findingBreath soundsAnimal CoVsHCoVsNew HavenDiseaseInfantsEtiological agentSubstantial proportionChain reactionChildrenSignificant proportionInfection
2004
Lymphoplasmacytic sclerosing pancreato-cholangitis: a case report and review of the literature.
Prasad P, Salem RR, Mangla R, Aslanian H, Jain D, Lee J. Lymphoplasmacytic sclerosing pancreato-cholangitis: a case report and review of the literature. The Yale Journal Of Biology And Medicine 2004, 77: 143-8. PMID: 15989743, PMCID: PMC2259126.Peer-Reviewed Original ResearchConceptsChronic pancreatitisAutoimmune pancreatitisPancreatic ductNon-alcoholic duct-destructive chronic pancreatitisDuct-destructive chronic pancreatitisPylorus-preserving Whipple procedureBenign formLymphoplasmacytic inflammatory infiltratePrimary sclerosing cholangitisBiliary tract diseaseAbdominal painObliterative phlebitisAutoimmune processSclerosing cholangitisWhipple procedureInflammatory infiltrateInterstitial fibrosisClinical entityCase reportTract diseasePancreatic adenocarcinomaDifferential diagnosisPancreatic carcinomaPancreaticobiliary diseasesPathological overlap
2001
Urine Detection of Survivin and Diagnosis of Bladder Cancer
Smith SD, Wheeler MA, Plescia J, Colberg JW, Weiss RM, Altieri DC. Urine Detection of Survivin and Diagnosis of Bladder Cancer. JAMA 2001, 285: 324-328. PMID: 11176843, DOI: 10.1001/jama.285.3.324.Peer-Reviewed Original ResearchMeSH KeywordsAdultAgedBiomarkers, TumorBlotting, WesternFemaleHumansInhibitor of Apoptosis ProteinsMaleMicrotubule-Associated ProteinsMiddle AgedNeoplasm ProteinsNeoplasm Recurrence, LocalPrognosisProteinsReverse Transcriptase Polymerase Chain ReactionSensitivity and SpecificityStatistics, NonparametricSurvivinUrinary Bladder NeoplasmsUrogenital NeoplasmsUrologic DiseasesConceptsRecurrent bladder cancerUrinary tract diseaseBladder cancerUrine samplesTract diseaseHealthy volunteersSurvivin levelsProstate-specific antigen levelLow-grade bladder cancerPrognostic molecular markersNoninvasive diagnostic testTranscriptase-polymerase chain reactionCommon human cancersUrine survivinGenitourinary cancersProgression of cancerAggressive diseaseAntigen levelsCervical cancerUrology clinicPolymerase chain reactionUnfavorable outcomeCystoscopy resultsRT-PCR methodSurvivin detection
2000
Noncalculous biliary obstruction in the child and adolescent11No competing interests declared.
Pryor J, Volpe C, Caty M, Doerr R. Noncalculous biliary obstruction in the child and adolescent11No competing interests declared. Journal Of The American College Of Surgeons 2000, 191: 569-578. PMID: 11085737, DOI: 10.1016/s1072-7515(00)00725-0.Peer-Reviewed Original ResearchConceptsYears of ageBiliary obstructionAge groupsPatients 21 yearsBile duct obstructionCommon duct stonesCases of cholecystitisHigh-risk groupObese adolescent girlsCourse of treatmentAbsence of stonesAcalculous cholecystitisYounger patientsDuct stonesMale patientsObstructive jaundiceDuct obstructionPatient 1Pediatric casesAdult casesBiliary operationsDiagnostic dilemmaTract diseaseMayo ClinicCommon cause
1977
Grey-scale ultrasound in the imaging of urinary tract disease.
Rosenfield A, Taylor K. Grey-scale ultrasound in the imaging of urinary tract disease. The Yale Journal Of Biology And Medicine 1977, 50: 335-53. PMID: 333791, PMCID: PMC2595534.Peer-Reviewed Original ResearchConceptsUrinary tract diseaseTract diseaseLower urinary tractRenal mass lesionsPelvic fluid collectionsRenal cystic diseaseSmall renal lesionsNon-invasive modalityGray-scale ultrasoundPerirenal abscessRenal abscessAdrenal lesionsAssociated lesionsRenal lesionsUrinary tractMass lesionProstatic tumorsCystic diseaseFluid collectionNormal anatomyLesionsDiseaseSpecific findingsUltrasoundAbscess
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