2025
Early diagnosis of axial spondyloarthritis among patients with chronic back pain using a clinical screening tool and referral strategy
Danve A, Alexander S, Afinogenova Y, Haims A, Park H, Maciejewski K, Deng Y, Odell W, Page N, Kang I. Early diagnosis of axial spondyloarthritis among patients with chronic back pain using a clinical screening tool and referral strategy. Rheumatology Advances In Practice 2025, 9: rkaf086. PMID: 40901640, PMCID: PMC12401578, DOI: 10.1093/rap/rkaf086.Peer-Reviewed Original ResearchChronic back painScreening QuestionnaireEarly diagnosisBack painAxial spondyloarthritisProspective studyEarly diagnosis of axial spondyloarthritisDiagnosis of axial spondyloarthritisPositive likelihood ratioClinical screening toolCBP patientsPrescreening questionsDiagnostic delayPhysical examinationReferral strategiesStudy visitsModifiable reasonsImaging studiesPatientsGold standardNon-radiographicAxSpAScreening toolPatient responseStudy proceduresNatriuretic response prediction equation for use with oral diuretics in heart failure
Ivey-Miranda J, Rao V, Cox Z, Moreno-Villagomez J, Mastache D, Collins S, Testani J. Natriuretic response prediction equation for use with oral diuretics in heart failure. European Heart Journal 2025, 46: 2410-2418. PMID: 40272149, PMCID: PMC12208776, DOI: 10.1093/eurheartj/ehaf268.Peer-Reviewed Original ResearchConceptsMechanisms of diuretic resistanceArea under the curvePoor diuretic responseDiuretic responseHeart failureDiuretic doseOral diureticsNatriuretic responseHF patient cohortsLoop diuretic doseOral loop diureticsUrine samplesTimed urine collectionsOral loopDiuretic resistanceLoop diureticsDiuretic administrationUrine volumePatient cohortUrine collectionStudy visitsDiureticsPatientsUrineDose2024 Update of the RECOVER-Adult Long COVID Research Index
Geng L, Erlandson K, Hornig M, Letts R, Selvaggi C, Ashktorab H, Atieh O, Bartram L, Brim H, Brosnahan S, Brown J, Castro M, Charney A, Chen P, Deeks S, Erdmann N, Flaherman V, Ghamloush M, Goepfert P, Goldman J, Han J, Hess R, Hirshberg E, Hoover S, Katz S, Kelly J, Klein J, Krishnan J, Lee-Iannotti J, Levitan E, Marconi V, Metz T, Modes M, Nikolich J, Novak R, Ofotokun I, Okumura M, Parthasarathy S, Patterson T, Peluso M, Poppas A, Quintero Cardona O, Scott J, Shellito J, Sherif Z, Singer N, Taylor B, Thaweethai T, Verduzco-Gutierrez M, Wisnivesky J, McComsey G, Horwitz L, Foulkes A, Cribbs S, Francis A, Hang T, Ingram K, Lainez J, Wiley Z, Lewis K, Ager A, Atha M, Fineman R, Gray N, Grimes A, Hewitt L, Huerta C, Johnson B, Khalil L, Kleinhenz D, Koumanelis A, Lee M, Litvack M, Panganiban B, Rahman K, Smith V, Stringer A, Tolbert M, Traenkner J, Unterberger K, Wimberly E, Han J, Marconi V, Ofotokun I, Patzer R, Walker T, Abraham R, Aguilar F, Ahmadi-Izad G, Ahmed D, Alvarez A, Anderson B, Asencios W, Beaty C, Bedi B, Berry J, Boone D, Bower M, Bremner J, Brent C, Brown-Smith K, Bull R, Capo G, Carl-Igwe K, Chitadze C, Chukwumerije N, Clyburn E, Collins S, Costello J, Couture G, Craft A, Cui X, del Rio C, Detelich J, Dixon C, Dow J, Doyle D, Elchommali J, Elsey I, Franks N, Gallini J, Gutter E, Harding J, Hernandez L, Holloway C, Ifejika C, Jasarevic R, Javia V, Jeter M, Joseph Y, Juarez M, Kirkpatrick C, Koumanelis A, Kozoman R, Krishnan S, Leon J, Lew V, Maier C, Makkaoui N, Maroney M, Martin C, Mbogo L, McCaslin A, McIntyre J, Moanna A, Montoya M, Morales E, Moran C, Murray C, Nelson R, Nguyen T, Ojoawo B, Osinski E, Oviedo S, Paredes-Gaitan Y, Prude M, Ramakrishnan G, Rebolledo P, Roberts M, Robinson K, Rogers C, Rouphael N, Searles C, Segall M, Shah A, Silva R, Simpson C, Simpson-Derrell K, Sirajud-Deen T, Stroud J, Suthar M, Sylber C, Sylvera A, Teunis L, Thomas K, Titanji K, Toy C, Truong A, Vaccarino V, Varney K, Vyas K, Vyas K, Walkow M, Wesley T, Winston J, Winter T, Wongtrakool C, Gander J, Neuman R, Bush P, Hudgins A, Kolailat I, Martinez M, Thompson S, Pemu P, Dandy A, Ibeawuchi C, Lawrence B, Morgan-Billingslea J, Ojemakinde E, Mullington J, Collier A, Fong T, Haack M, Hauser K, Maley J, Quintana Y, Shaughnessy L, Stephenson K, Thomas R, Torres R, Marathe J, Duffy E, Hamburg N, Kobayashi M, O'Connor G, Shepherd F, Williams C, Zhang H, Levy B, Aikawa M, Baden L, Baslet G, Bennett L, Bhattacharyya S, Buring J, Cagnina R, Chen L, Clark C, Cohen P, Czeisler C, Estill P, Gay E, Hong J, Lamas D, Levy-Carrick N, Manson J, Monafrared T, Redline S, Remis E, Schilkrut D, Sesso H, Solomon S, Sparks J, Spencer L, Systrom D, Thu P, Walt D, Washko G, Whittelsey M, Wiener R, John J, Ticotsky A, Bassett I, Alba G, Aung T, Ginns L, Haas J, Hu Y, Juelg B, Kanjilal D, Kim A, Klerman E, Lewis G, Ojikutu B, Perlis R, Rosand J, Wallace Z, Xerras D, Zionts D, Ward H, Blazey-Martin D, Ghamloush M, Jordan M, Kogelman L, Carton T, Miele L, Brown T, Sutherland E, Fuloria J, Datri P, Hagensee M, Leggio C, Perkins A, Trauth A, Trotter S, Van Deerlin A, Weiser S, Young M, Erdmann N, Levitan E, Tita A, Armstrong D, Binkley S, Blackwell K, Causey A, Cook F, Domingo J, Donahue C, Eady M, Edberg J, Garcia-McClaney N, Garner M, Gray B, Hall W, Hart C, Hebson C, Hidalgo B, Holtzapfel K, Jinright A, Judd S, Kennedy T, Kirkwood L, Maier M, McCormack P, Mitchell K, Montgomery A, Peralta-Carcelen M, Pilco J, Powell L, Shevin R, Skipworth S, Spurgeon L, Ware G, Wilson R, Woodruff D, Young B, Gillespie M, Daniel C, Hansel J, Wu J, Ashktorab H, Brim H, Laiyemo A, Sherif Z, Durrani S, Nezamloo A, Ngwa J, Njoku N, Gentil M, Mehari A, Solemani A, Chang L, Thuluvath P, Alemu M, Anderson J, Chauhan M, Cho S, Goodman K, Lanke G, Lebron R, Maheshwari A, Ok J, To C, Shellito J, Greenway F, Kirwan J, Rosen C, Arruda A, Emery I, Roelke T, Berger P, Hoover S, Black L, Tjarks B, Fonseca V, Gupta S, Longo M, Yang M, Shikuma C, Chow D, MarGangcuangco L, Castro M, Bengtson C, Howard T, Koontz B, Spikes L, Simmons C, Whiteheart S, Garvy B, Wood J, Marshall G, Garla V, Kuebler J, Nandi U, Vasey A, Warren D, Dickinson J, VanWagoner T, Bogie A, James J, Scott J, Sukhera F, Luciano Roman C, Perez Frontera S, Santana Bagur J, Hodder S, Bardes J, Dominique-Villanueva D, Juskowich J, Reece R, Sarwari A, Certa M, Chessier E, Everett E, Kindred E, Harris P, Sudhindra P, Olds L, Aponte-Soto L, Del Rios M, Diaz M, Ibanez A, Rolon C, Cranford S, Brown D, Dixon J, Gale L, Hammerl S, Hartwig K, Madineni A, Swearingen P, Hendrickson M, Noland S, Terlinde T, Hobbs B, Klein J, Krishnan J, Lin J, Muramatsu N, Prabhakar B, Prendergast H, Vanden Hoek T, Adams D, Baker A, Barbera S, Basu S, Bleasdale S, Boyd A, Breiter T, Buhimschi I, Carrithers M, Chalamalla R, Chestek D, Cook J, Darbar D, Dasgupta R, Davis Blakley F, DeLisa J, Diviak K, Donlon M, Dworkin M, Ellison A, Flanigan C, Freedman M, Gerald L, Giles W, Gordon H, Hammad B, Hasek S, Hasse W, Hryniewicka M, Illendula S, Ismail N, Jain A, Jennette K, Kadubek G, Kent D, Kent D, Kim K, Kotini-Shah P, Large L, Lash J, Lu J, Mahamed A, Malchenko S, Martinez M, Mauntel-Medici C, McCauley M, Menchaca M, Mermelstein R, Moreno D, Morrissy L, Musick H, Norwick L, Novak R, Ortiz M, Patel K, Perez N, Pliskin N, Pope S, Prasad B, Predki B, Quigley J, Ramchandran R, Ramirez A, Rappe S, Rehman J, Rowley M, Rudraraju G, Rutherfoord M, Sculley J, Smith-Mack J, Sun J, Tartt N, Villanueva L, Warfield Kelly S, Yazici C, Stewart de Ramirez S, Bolliger D, Boyineni J, Chebrolu P, Curry H, Donohue S, Edmonds S, Kelly S, Maholovich P, Sader S, Thompson T, Welter H, Woolley B, Hafner J, Hanson K, Hutton R, Charney A, Kovatch P, Merad M, Nadkarni G, Wisnivesky J, Aberg J, Ascolillo S, Bagiella E, Bartram L, Becker J, Beckmann N, Bendl A, Chen B, Civil A, Crawford G, Dhar K, Evo-Ortega L, Fierer D, Gallagher E, Garcia-Sastre A, Gnjatic S, Gray I, Guliyeva S, Harvey-Ingram L, Herrera-Moreno J, Hill M, Horowitz C, Jackson R, Kastrat D, Lala-Trindade A, Lin J, Macaluso N, Marcon K, Meyer D, Morinigo J, Natelson B, Nussenzweig M, Padua T, Putrino D, Richardson L, Russo S, Seifert A, Serri A, Walker J, Yee M, Bateman L, Vernon S, Deakyne Davies S, Gardner E, Bryan T, Buck K, Hawkins K, Oakes J, Horne B, Knowlton K, Woller S, Aguirre B, Anderson J, Bair T, Bosh L, Evans L, Garrett C, Harris D, Herrera K, Iverson L, Jensen M, Juan J, Knight S, Leither L, Maestas H, May H, Najarian G, Webb T, Zubal S, Erlandson K, Sokol R, Brightman M, Davis D, Feuerriegel E, Fudge H, Garg L, Graham P, Higgins J, Johnson B, Jolley S, Lockie T, McCandless S, Molden J, Owen M, Pitch C, Reid K, Reusch J, Thurman B, Tran H, West S, Wodushek T, Friedman N, Ludwig K, Decker L, Raissy H, Adolphi N, Archuleta D, Bradfute S, Brito R, Elifritz J, Garcia-Soberanez N, Gentry F, Harkins M, Martinez N, Montoya L, Parada A, Quinn D, Ramos A, Sheehan E, Treacher I, Hess R, Truong D, Alekhina N, Barlocker J, Brown J, Cortez M, Donohue D, Facelli J, Ford I, Gouripeddi R, Hermansen J, Johnny J, Lindsay A, Ling L, Lloyd J, Lu Y, Medina J, Morimoto S, Pace L, Powell J, Scholand M, Shah K, Sharareh N, Spivak A, Stringham C, Trinity J, Velinder M, Weaver L, Kaelber D, McComsey G, Adams C, Atieh O, Baissary J, Baloi A, Barnboym E, Boldt N, Conrad A, Consolo M, Curtis L, D’anza B, DiFrancesco K, Eteshola E, Gallagher M, Harris P, Hernandez C, Hershey M, Iqbal S, Jacob J, Kennedy O, Labbato D, Levert A, Levin J, Lim J, Malakooti S, Mouchati C, Pearman A, Pettinato K, Rivera A, Rodgers M, Rodgers T, Roy A, Scott S, Sheth N, Smith B, Tejani V, Tribout M, Yendewa G, Zhang D, Zisis S, Singer N, Ayache M, Chesnick H, Edminston M, Greenwood C, Haghiac M, Kaufman E, Lengu K, Lowenthal R, Oleson C, Smith C, Weinberger E, Chen P, Caudill A, Chopra T, Contreras F, Dahlke L, Gudipudi L, Jackman S, Modes M, Muttera N, Parimon T, Salinas N, Tadeo J, Torbati S, Heath J, Brennan C, Edmark R, Gutierrez V, Hadlock J, Li S, Magis A, McDonald C, Murray K, Rowen L, Yuan D, Tuttle K, Alicic R, Baxter J, Emerson S, Hood S, Kuykendall K, White S, Wilcox L, Goldman J, Algren H, Del Alcazar J, Duven A, Kaneko J, Kim C, Manner P, Mason C, Poussier R, Satira R, Wallick J, Chu H, Harteloo A, Kemp M, Logue J, McCaffrey K, McDonald D, Nackviseth C, Nguyen H, Watanabe K, Hasbani K, Nambiar A, Patterson T, Potter J, Salehi M, Sharma K, Verduzco-Gutierrez M, Anderson R, Arellanes A, Barajas R, Chauhan S, Clarke G, Farner C, Fischer M, Goldberg M, Hastings G, Heard P, Hernandez J, Herrera I, Infante E, Johnson H, Jones J, Kellogg D, Kraig E, Longoria L, Okafor E, Patterson J, Pinones A, Reeves W, Scholler I, Seshadri S, Shah P, Shah D, Soileau B, Solis P, Stoebner C, Sullivan M, Taylor B, Tragus R, Tsevat J, Saade G, Sharma K, Paredes C, Alvarado S, Blish C, Go M, Jagannathan P, Maldonado Y, Singh U, Utz P, Ahuja N, Blomkalns A, Bonilla H, Brotherton R, Clinton K, Dingankar V, Geng L, Haddad F, Jamero C, Jee K, Jia X, Khurana N, Kumar A, Miglis M, O'Conor E, Olszewski K, Pathak D, Quintero O, Saperia C, Scott J, Urdaneta A, Varkey M, Reiman E, Bime C, Hansen L, Hughes T, Lieberman D, Soto F, Wilson C, Lee-Iannotti J, Autry L, Borwege S, Copeland J, DiLise-Russo M, Fadden S, Gomez I, Grischo G, Hartley W, Hillier L, Ismail H, Iusim S, James M, Kala M, Kim D, Murthy G, Unzek S, Vadovicky S, Veres S, Nikolich J, Parthasarathy S, Ernst K, Esquivel D, Harris D, Harris S, Hernandez M, Hsu H, Karnafel M, Knox K, Koleski A, LaFleur B, Lambert B, LaRue S, Lutrick K, Merchant N, Morton C, Mosier J, Olorunnisola T, Peralta J, Pilling W, Pogreba-Brown K, Rischard F, Ryan L, Smith T, Snyder M, Subbian V, Suhr K, Velarde D, Deeks S, Kelly J, Martin J, Peluso M, Anderson G, Anglin K, Argueta U, Asare K, Buitrago M, Chang Song C, Clark A, Conway E, Del Castillo N, Deswal M, Durstenfeld M, Eilkhani E, Eun A, Fehrman E, Figueroa T, Flores D, Grebe H, Henrich T, Hoh R, Hsue P, Huang B, Ibrahim R, Kerbleski M, Kirtikar R, Lew M, Lombardo J, Lopez M, Luna M, Marquez C, Munter S, Ngo L, Pineda-Ramirez J, Rhoads K, Rodriguez A, Romero J, Ryder D, So M, Somsouk M, Tai V, Tran B, Uy J, Valdivieso D, Verma D, Williams M, Zamora A, Newman L, Abella J, Barnette Q, Bevc C, Beverly J, Ceger P, Croxford J, Enger M, Fain K, Farris T, Hanlon S, Hines D, Johnson-Lawrence V, Jordan K, Lefebvre C, Linas B, Luukinen B, Mandal M, McKoy N, Nance S, Pasquarelli D, Quiner C, Sembajwe R, Shaw G, Thornburg V, Tosco K, Wright H, Gross R, Hochman J, Horwitz L, Katz S, Troxel A, Adler L, Akinbo P, Almenana R, Aschalew M, Balick L, Bello O, Bhuiyan S, Blachman N, Branski R, Briscoe J, Brosnahan S, Bueler E, Burgos Y, Caplin N, Chaplin D, Chen Y, Cheng S, Choe P, Choi J, Chung A, Church R, Cobos S, Croft N, Cruz Irving A, Del Boccio P, Díaz I, Divers J, Doshi V, Dreyer B, Ebel S, Esquenazi-Karonika S, Faustin A, Febres E, Fine J, Fink S, Freeland C, Frontera J, Gallagher R, Gonzalez-Duarte A, Hasson D, Hill S, Hossain J, Islam S, Johnson S, Kansal N, Kenney R, Kershner T, Kewlani D, Kwak J, Lamendola-Essel M, Laury S, Laynor G, Lei L, Leon T, Lewczak Z, Linton J, Logan M, Malik N, Mamistvalova L, Mandel H, Maranga G, Mathews P, Mattoo A, Mei T, Mendelsohn A, Mercier E, Millar Vernetti P, Miller M, Mitchell M, Moreira A, Mudumbi P, Nahin E, Nair N, Nekulak J, Owens K, Parent B, Patibandla N, Petrov P, Postelnicu R, Pratt F, Randall I, Rao P, Rapkiewicz A, Rizzo J, Rosas J, Rose C, Saint-Jean C, Santacatterina M, Shah B, Shaukat A, Simon N, Simsir A, Stinson M, Tang W, Tatapudi V, Thawani S, Thomas M, Thorpe L, Tom M, Treiha E, Truong J, Udosen M, Valencia C, Velazquez-Perez J, Vernetti P, Vidal C, Viswanathan A, Willerford A, Williams N, Wong C, Wood M, Wuller S, Yin S, Young C, Zaretsky J, Zavlunova S, Foulkes A, Karlson E, Murphy S, Ahirwar S, Ahmed S, Ainsworth L, Atchley-Challenner R, Avilach P, Balan T, Benik N, Benoit B, Bind M, Bonaventura W, Boutin N, Brion B, Cagan A, Cai T, Cao T, Castro V, Cerretani X, Chan J, Cheng D, Chibnik L, Ciriello M, Costenbader K, Dimitrov D, Estiri H, Fayad M, Feldman C, Gainer V, Ghosh B, Gollub R, Guan Z, Harris A, Helmer K, Hendrix A, Holzbach A, Huang W, Kaufman D, Keogh D, Kerr J, Klann J, Krishnamoorthy A, Lasky-Su J, Liao K, MacFadden D, Maram A, Martel M, Mendis M, Metta R, Monteiro J, Morales E, Morse R, Nazaire M, Neils G, Nguyen A, Norman J, Paik H, Pant D, Park H, Rabideau D, Reeder H, Rossi-Roh K, Santacroce L, Schlepphorst K, Schulte C, Selvaggi C, Shinnick D, Simons W, Simpson L, St. Jean Flanders M, Strasser Z, Thakrar M, Thaweethai T, Thorn M, Trewett P, Van Fleet D, Wagholikar K, Wang T, Wattanasin N, Weber G, Williams M, Zhang R, Cicek M, Flotte T, Boysen E, Chang N, Ellingworth E, Frisch E, Welch G, Yusuf A, Zahnle N, Cerda M, Clash V, Taylor B, Zissis M, Akintonwa T, Blancero F, Brown H, Carmilani M, Copeland D, Hall Y, kondo K, Lerma L, Lindsay J, Marti H, Maughan C, Minor T, Vincent H, Aragon L, Bander B, Bishof K, Carignan E, Castro Baucom L, Clash V, Coombs K, Corchado C, Davis H, Diggs M, Dunn M, Edwards B, Fisher L, Fitzgerald M, Gage Witvliet M, Gustafson T, Holmes V, Hornig M, Hornig M, Jain N, Kochis N, Lam J, Letts R, Lewis J, Martinez T, McCorkell L, McGrath R, Nguyen K, Nichols L, O'Brien L, Peddie A, Perlowski A, Phillips-Lorenzo E, Prentiss L, Raytselis N, Regino L, Rockwell M, Rutter J, Seibert E, Sekar A, Taylor E, Wallace A, Wilensky R, Williams M, Williams N, Williams-Dawson K, Wylam A. 2024 Update of the RECOVER-Adult Long COVID Research Index. JAMA 2025, 333: 694-700. PMID: 39693079, PMCID: PMC11862971, DOI: 10.1001/jama.2024.24184.Peer-Reviewed Original ResearchConceptsLong COVIDQuality-of-life measuresStudy visitsPost-COVID-19 conditionObservational cohort studyMain OutcomesPatient communityParticipant dataParticipant-reported symptomsCohort studyPostexertional malaiseSymptom listSARS-CoV-2 infectionShortness of breathParticipantsEnhanced recoveryBrain fogAdultsResearch indexVisitsChest painSymptomsPost-COVID-19Symptom subtypesChronic coughIncidence and Prevalence of Post-COVID-19 Myalgic Encephalomyelitis: A Report from the Observational RECOVER-Adult Study
Vernon S, Zheng T, Do H, Marconi V, Jason L, Singer N, Natelson B, Sherif Z, Bonilla H, Taylor E, Mullington J, Ashktorab H, Laiyemo A, Brim H, Patterson T, Akintonwa T, Sekar A, Peluso M, Maniar N, Bateman L, Horwitz L, Hess R. Incidence and Prevalence of Post-COVID-19 Myalgic Encephalomyelitis: A Report from the Observational RECOVER-Adult Study. Journal Of General Internal Medicine 2025, 40: 1085-1094. PMID: 39804551, PMCID: PMC11968624, DOI: 10.1007/s11606-024-09290-9.Peer-Reviewed Original ResearchSARS-CoV-2 infectionLongitudinal observational cohort studyClinical diagnostic criteriaSelf-reported symptomsResultsThe incidence rateBackgroundMyalgic encephalomyelitis/chronic fatigue syndromeTiming of SARS-CoV-2 infectionPost-exertional malaiseObservational cohort studyUninfected participantsPost-AcuteSARS-CoV-2Diagnostic criteriaCohort studyHazard ratioStudy visitsFatigue syndromeParticipantsEnhanced recoveryME/CFS symptomsLong COVIDMyalgic encephalomyelitisDays of infectionPrevalenceInfected participants
2024
Measuring clinically relevant change in apathy symptoms in ADMET and ADMET 2
Tumati S, Herrmann N, Perin J, Rosenberg P, Lerner A, Mintzer J, Padala P, Brawman-Mintzer O, van Dyck C, Porsteinsson A, Craft S, Levey A, Shade D, Lanctôt K. Measuring clinically relevant change in apathy symptoms in ADMET and ADMET 2. International Psychogeriatrics 2024, 36: 1232-1244. PMID: 39297292, PMCID: PMC11695175, DOI: 10.1017/s1041610224000711.Peer-Reviewed Original ResearchDementia Apathy Interview and RatingMinimal Clinically Important DifferenceDistribution-based analysisMeasure clinically relevant changesClinically Important DifferenceClinically significant apathyAnchor-based analysesDementia careGlobal Impression of ChangeImpression of ChangeLinear mixed modelsAlzheimer's diseaseClinically relevant changesMMSE scoreImportant differenceApathy symptomsApathy ScaleControlled TrialsSignificant apathyAnchor measuresDementiaStudy visitsApathy severityMethylphenidate trialSymptom severitySex Differences in Hypertension and Its Management Throughout Life
Yeo W, Abraham R, Surapaneni A, Schlosser P, Ballew S, Ozkan B, Flaherty C, Yu B, Bonventre J, Parikh C, Kimmel P, Vasan R, Coresh J, Grams M. Sex Differences in Hypertension and Its Management Throughout Life. Hypertension 2024, 81: 2263-2274. PMID: 39229711, PMCID: PMC11483212, DOI: 10.1161/hypertensionaha.124.22980.Peer-Reviewed Original ResearchPrevalence of hypertensionUncontrolled hypertensionChronic kidney disease progressionPrevalence of uncontrolled hypertensionKidney disease progressionBody mass indexClasses of medicationsSex differencesEstimate sex differencesCoronary heart diseaseHeart failureMass indexAntihypertensive medicationsDisease progressionStudy visitsAtherosclerosis RiskHypertensionHigh riskHypertensive individualsHeart diseaseLife courseCommunity studiesPrevalenceMedicationDifferentiation of Prior SARS-CoV-2 Infection and Postacute Sequelae by Standard Clinical Laboratory Measurements in the RECOVER Cohort.
Erlandson K, Geng L, Selvaggi C, Thaweethai T, Chen P, Erdmann N, Goldman J, Henrich T, Hornig M, Karlson E, Katz S, Kim C, Cribbs S, Laiyemo A, Letts R, Lin J, Marathe J, Parthasarathy S, Patterson T, Taylor B, Duffy E, Haack M, Julg B, Maranga G, Hernandez C, Singer N, Han J, Pemu P, Brim H, Ashktorab H, Charney A, Wisnivesky J, Lin J, Chu H, Go M, Singh U, Levitan E, Goepfert P, Nikolich J, Hsu H, Peluso M, Kelly J, Okumura M, Flaherman V, Quigley J, Krishnan J, Scholand M, Hess R, Metz T, Costantine M, Rouse D, Taylor B, Goldberg M, Marshall G, Wood J, Warren D, Horwitz L, Foulkes A, McComsey G. Differentiation of Prior SARS-CoV-2 Infection and Postacute Sequelae by Standard Clinical Laboratory Measurements in the RECOVER Cohort. Annals Of Internal Medicine 2024, 177: 1209-1221. PMID: 39133923, PMCID: PMC11408082, DOI: 10.7326/m24-0737.Peer-Reviewed Original ResearchPostacute sequelae of SARS-CoV-2 infectionSARS-CoV-2 infectionLaboratory markersSARS-CoV-2Laboratory valuesUrinary albumin-creatinine ratioClinical laboratory markersStandard clinical laboratory testsAlbumin-creatinine ratioClinical laboratory valuesHemoglobin A<sub>1c</sub> (HbA<sub>1c</sub>Clinically useful biomarkersClinical laboratory testsClinical laboratory measurementsPropensity score adjustmentSequelae of SARS-CoV-2 infectionPreexisting diabetesIndex dateMeasured 6 monthsClinical significanceNational Institutes of HealthStudy visitsEnrollment siteRisk factorsClinical biomarkersPost–Acute Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) After Infection During Pregnancy
Metz T, Reeder H, Clifton R, Flaherman V, Aragon L, Baucom L, Beamon C, Braverman A, Brown J, Cao T, Chang A, Costantine M, Dionne J, Gibson K, Gross R, Guerreros E, Habli M, Hadlock J, Han J, Hess R, Hillier L, Hoffman M, Hoffman M, Hughes B, Jia X, Kale M, Katz S, Laleau V, Mallett G, Mehari A, Mendez-Figueroa H, McComsey G, Monteiro J, Monzon V, Okumura M, Pant D, Pacheco L, Palatnik A, Palomares K, Parry S, Pettker C, Plunkett B, Poppas A, Ramsey P, Reddy U, Rouse D, Saade G, Sandoval G, Sciurba F, Simhan H, Skupski D, Sowles A, Thorp J, Tita A, Wiegand S, Weiner S, Yee L, Horwitz L, Foulkes A, Jacoby V. Post–Acute Sequelae of Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) After Infection During Pregnancy. Obstetrics And Gynecology 2024, 144: 411-420. PMID: 38991216, PMCID: PMC11326967, DOI: 10.1097/aog.0000000000005670.Peer-Reviewed Original ResearchSARS-CoV-2 infectionSARS-CoV-2Clinical characteristicsSevere acute respiratory syndrome coronavirus 2Gastrointestinal symptomsAcute respiratory syndrome coronavirus 2Respiratory syndrome coronavirus 2Risk factorsPost-acute sequelae of severe acute respiratory syndrome coronavirus 2Syndrome coronavirus 2Acute SARS-CoV-2 infectionHistory of obesityMulticenter cohort studyAssociated with increased prevalenceMultivariate logistic regression modelPostexertional malaiseCoronavirus 2Median timeAcute infection severityLogistic regression modelsAcute infectionCohort studyPredominant symptomPrimary outcomeStudy visits728-P: Experience with Teplizumab in the PROTECT Type 1 Diabetes (T1D) Study during the COVID-19 Pandemic
GITELMAN S, HEROLD K, SIMMONS K, SUMNIK Z, KNECHT L, NIEMOELLER E, TIAN W, COMER G, MILLER D, RAMOS E. 728-P: Experience with Teplizumab in the PROTECT Type 1 Diabetes (T1D) Study during the COVID-19 Pandemic. Diabetes 2024, 73 DOI: 10.2337/db24-728-p.Peer-Reviewed Original ResearchPBO groupTeplizumab groupAnti-CD3 monoclonal antibodyStudy drug discontinuationRates of overall infectionHumanized anti-CD3 monoclonal antibodyIncidence of infectionType 1 diabetesAdministered 6 monthsDrug discontinuationImmunomodulatory therapyTeplizumabAntiviral treatmentModified doseStudy visitsOverall infectionProtocol deviationsMonoclonal antibodiesTreatment groupsInfectionTherapyAged 8COVID-19COVID-19 testingTreatmentAssociations of urinary polycyclic aromatic hydrocarbon (PAH) metabolites and their mixture with thyroid hormone concentration during pregnancy in the LIFECODES cohort: A repeated measures study
Park S, Siwakoti R, Ferguson K, Cathey A, Hao W, Cantonwine D, Mukherjee B, McElrath T, Meeker J. Associations of urinary polycyclic aromatic hydrocarbon (PAH) metabolites and their mixture with thyroid hormone concentration during pregnancy in the LIFECODES cohort: A repeated measures study. Environmental Research 2024, 255: 119205. PMID: 38782334, PMCID: PMC11421857, DOI: 10.1016/j.envres.2024.119205.Peer-Reviewed Original ResearchMaternal thyroid hormonesThyroid hormone concentrationsPolycyclic aromatic hydrocarbon metabolitesThyroid hormonesPolycyclic aromatic hydrocarbonsPregnancy outcomesHormone concentrationsFetal sex-specific effectsPAH exposureBayesian kernel machine regressionPotential non-linear associationsHormone physiologyAromatic hydrocarbonsThyroid hormone physiologyPregnancy physiologyFetal growthFetal sexFetal developmentUrinary PAH metabolitesSerial measurementsPregnancyUrinary polycyclic aromatic hydrocarbonsPolycyclic aromatic hydrocarbon exposureStudy visitsThyroidThe relationship of pain intensity and opioid craving with delayed methadone dose: A preliminary study of individuals with opioid use disorder
MacLean R, Spinola S, Pittman B, Meyerovich J, Szollosy S, Wolkowicz N, Minnix S, Sofuoglu M. The relationship of pain intensity and opioid craving with delayed methadone dose: A preliminary study of individuals with opioid use disorder. British Journal Of Clinical Pharmacology 2024, 90: 2977-2984. PMID: 38439592, PMCID: PMC11613043, DOI: 10.1111/bcp.16027.Peer-Reviewed Original ResearchCold pressor testMethadone doseExperience of painOpioid cravingMethadone conditionTime course of painRelationship of pain intensityDose conditionsCourse of painAssessment of painOpioid use disorderCross-over designPain intensityPain thresholdIncreased riskPainStudy visitsPressor testDelayed dosesUse disorderCravingOpioidMethadone treatmentDoseMethadone
2023
Barriers and facilitators to recruitment of underrepresented research participants: Perspectives of clinical research coordinators
Heffernan M, Barrera L, Guzman Z, Golbeck E, Jedraszko A, Hays P, Herzog K, D’Aquila R, Ison M, McColley S. Barriers and facilitators to recruitment of underrepresented research participants: Perspectives of clinical research coordinators. Journal Of Clinical And Translational Science 2023, 7: e193. PMID: 37745931, PMCID: PMC10514687, DOI: 10.1017/cts.2023.611.Peer-Reviewed Original ResearchImplicit bias measuresCultural competency trainingClinical research coordinatorsFacilitators to recruitmentBias measuresImpact of cultural competence trainingCompetency trainingProspective participantsGeneralizability of research findingsResearch participantsResearch coordinatorsPediatric academic medical centerIn-person study visitsParticipants' languageAcademic medical centerAssociated with intentionExamined barriersImprove recruitmentParticipantsIn-personResearch literacySurvey topicsMedical CenterStudy visitsCompensate participantsAdverse birth outcomes are associated with circulating matrix metalloproteinases among pregnant women in Puerto Rico
Kim C, Cathey A, Watkins D, Mukherjee B, Rosario-Pabón Z, Vélez-Vega C, Alshawabkeh A, Cordero J, Meeker J. Adverse birth outcomes are associated with circulating matrix metalloproteinases among pregnant women in Puerto Rico. Journal Of Reproductive Immunology 2023, 159: 103991. PMID: 37454540, PMCID: PMC10726844, DOI: 10.1016/j.jri.2023.103991.Peer-Reviewed Original ResearchConceptsBirth outcomesMatrix metalloproteinasesFetal sexPregnant womenFemale fetusesNewborn lengthVisit 3Associated with increased odds of preeclampsiaVisit 1Impact of matrix metalloproteinasesCustomized Luminex assayGestational diabetes mellitusOdds of preeclampsiaAdverse birth outcomesAssociated with increased oddsGestational ageHealthy pregnancyMale fetusesUterine remodelingLuminex assayLogistic regression modelsDiabetes mellitusStudy visitsInverse associationExtracellular matrix
2022
Absence of long-term changes in urine biomarkers after AKI: findings from the CRIC study
McCoy I, Hsu J, Bonventre J, Parikh C, Go A, Liu K, Ricardo A, Srivastava A, Cohen D, He J, Chen J, Rao P, Muiru A, Hsu C. Absence of long-term changes in urine biomarkers after AKI: findings from the CRIC study. BMC Nephrology 2022, 23: 311. PMID: 36100915, PMCID: PMC9472364, DOI: 10.1186/s12882-022-02937-x.Peer-Reviewed Original ResearchConceptsChronic Renal Insufficiency CohortUrine biomarkersMCP-1/CrKIM-1/CrCKD progressionNon-AKI groupChronic Renal Insufficiency Cohort StudyEffect of AKIPre-hospital characteristicsUrine protein/creatinine ratioBanked urine samplesCohort of adultsProtein/creatinine ratioProgressive CKDStudy visitsAKICKDUrineUrine samplesAKI hospitalizationsAlbumin/CrLong-term changesNon-AKI hospitalizationsPre-hospitalBiomarkers
2021
Individual and joint effects of phthalate metabolites on biomarkers of oxidative stress among pregnant women in Puerto Rico
Cathey A, Eaton J, Ashrap P, Watkins D, Rosario Z, Vega C, Alshawabkeh A, Cordero J, Mukherjee B, Meeker J. Individual and joint effects of phthalate metabolites on biomarkers of oxidative stress among pregnant women in Puerto Rico. Environment International 2021, 154: 106565. PMID: 33882432, PMCID: PMC9923976, DOI: 10.1016/j.envint.2021.106565.Peer-Reviewed Original ResearchConceptsBayesian kernel machine regressionPhthalate metabolitesEnvironmental risk scoreBiomarkers of oxidative stressPregnant womenPhthalate mixtureBayesian kernel machine regression analysisEffects of phthalate metabolitesOxidative stressIndividual phthalate metabolitesLipid oxidative stressUrinary biomarker measurementsKernel machine regressionAdverse birth outcomesPuerto Rico TestsiteOxidative stress biomarkersChemical fractionationContamination threatLongitudinal birth cohortPhthalate compoundsLinear mixed effects modelsBirth outcomesOxidative stress mechanismsStudy visitsPhthalate exposure
2019
A repeated measures study of phenol, paraben and Triclocarban urinary biomarkers and circulating maternal hormones during gestation in the Puerto Rico PROTECT cohort
Aker A, Ferguson K, Rosario Z, Mukherjee B, Alshawabkeh A, Calafat A, Cordero J, Meeker J. A repeated measures study of phenol, paraben and Triclocarban urinary biomarkers and circulating maternal hormones during gestation in the Puerto Rico PROTECT cohort. Environmental Health 2019, 18: 28. PMID: 30940137, PMCID: PMC6444601, DOI: 10.1186/s12940-019-0459-5.Peer-Reviewed Original ResearchConceptsUrinary biomarkersAssociated with adverse birth outcomesAdverse birth outcomesPregnant womenBirth outcomesAdverse outcomesSerum hormonesStudy visitsParaben biomarkersThyroid hormonesParaben exposurePercent changeHormoneBiomarker concentrationsMaternal hormonesBiomarkersOutcomesVisitsAssociationExposureGestationRandom interceptPregnancyThyroid
2018
The associations between prenatal exposure to triclocarban, phenols and parabens with gestational age and birth weight in northern Puerto Rico
Aker A, Ferguson K, Rosario Z, Mukherjee B, Alshawabkeh A, Cordero J, Meeker J. The associations between prenatal exposure to triclocarban, phenols and parabens with gestational age and birth weight in northern Puerto Rico. Environmental Research 2018, 169: 41-51. PMID: 30412856, PMCID: PMC6347499, DOI: 10.1016/j.envres.2018.10.030.Peer-Reviewed Original ResearchConceptsAssociated with gestational ageGestational ageOdds of SGAInfant sexBirth outcomesStudy visitsVisit 1Odds of preterm birthOdds of LGAAssociated with adverse birth outcomesBirthweight z-scoreBiomarker concentrationsAdverse birth outcomesPuerto Rico TestsitePreterm birthPregnant womenBirth weightUrinary biomarker concentrationsExposure biomarkersLogistic regression modelsVisit 3SGADecreased oddsZ-scoreCalculate oddsAssociations between maternal plasma measurements of inflammatory markers and urinary levels of phenols and parabens during pregnancy: A repeated measures study
Aung M, Ferguson K, Cantonwine D, Bakulski K, Mukherjee B, Loch-Caruso R, McElrath T, Meeker J. Associations between maternal plasma measurements of inflammatory markers and urinary levels of phenols and parabens during pregnancy: A repeated measures study. The Science Of The Total Environment 2018, 650: 1131-1140. PMID: 30308801, PMCID: PMC6236678, DOI: 10.1016/j.scitotenv.2018.08.356.Peer-Reviewed Original ResearchConceptsPlasma inflammatory markersInflammatory markersC-reactive proteinInterquartile range increaseFetal developmentImmunological biomarkersRange increaseTumor necrosis factor-aCase-control studyProspective birth cohortImmune system regulationHealthy pregnancyUrinary phenolSystemic inflammationImmunological mechanismsInterleukin-10Urinary levelsInterleukin-1bPregnancyStudy visitsMultivariate linear mixed modelReproductive outcomesMeasures of exposureInverse probability weightingUrine samplesFoetal ultrasound measurement imputations based on growth curves versus multiple imputation chained equation (MICE)
Ferguson K, Yu Y, Cantonwine D, McElrath T, Meeker J, Mukherjee B. Foetal ultrasound measurement imputations based on growth curves versus multiple imputation chained equation (MICE). Paediatric And Perinatal Epidemiology 2018, 32: 469-473. PMID: 30016545, PMCID: PMC6939297, DOI: 10.1111/ppe.12486.Peer-Reviewed Original ResearchConceptsLinear mixed modelsComplete-case analysisMultiple imputationEpidemiological studies of risk factorsImputed datasetsComplete-caseDemographic factorsStudy of risk factorsLIFECODES birth cohortUltrasound measurementsCalculate associationsBirth cohortCross-sectionEpidemiological studiesRisk factorsStudy visitsLongitudinal analysisParametric linear mixed modelImputationMissing DataMixed modelsLongitudinal measurementsSample sizeCovariate dataGrowth restriction
2017
Environmental phenol associations with ultrasound and delivery measures of fetal growth
Ferguson K, Meeker J, Cantonwine D, Mukherjee B, Pace G, Weller D, McElrath T. Environmental phenol associations with ultrasound and delivery measures of fetal growth. Environment International 2017, 112: 243-250. PMID: 29294443, PMCID: PMC5899051, DOI: 10.1016/j.envint.2017.12.011.Peer-Reviewed Original ResearchConceptsInverse associationBirth weight z-scoreWeight z-scoreZ-scoreFetal weightInterquartile range differenceFetal growthBirth weightUltrasound estimationUltrasound estimation of fetal weightEstimation of fetal weightLIFECODES birth cohortStandard deviation decreaseEstimated Fetal WeightBirth cohortOutcome measuresInvestigate sex differencesWomen's HospitalPregnant womenStudy populationStudy visitsDeviation decreaseDelivery measuresPregnancyAssociation
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