2024
Back to Normal? Harnessing Long Short-term Memory Network to Examine the Associations Between Adolescent Social Interactions and Depressive Symptoms During Different Stages of COVID-19
Polack R, Zhang A, Kober H, Joormann J, Benisty H. Back to Normal? Harnessing Long Short-term Memory Network to Examine the Associations Between Adolescent Social Interactions and Depressive Symptoms During Different Stages of COVID-19. Research On Child And Adolescent Psychopathology 2024, 52: 1621-1633. PMID: 38922462, DOI: 10.1007/s10802-024-01208-7.Peer-Reviewed Original ResearchDepressive symptomsSocial interactionMental healthPredicting Depressive SymptomsDaily social interactionsAdolescent social interactionsAdolescents' social environmentAge differencesDevelopmental periodAdolescentsSymptomsSocial environmentPre-pandemic patternsSocial influenceMemory networkStages of COVID-19Seventy-nineChronic stageLong-short term memory recurrent networkYouthDepressionDiaryCOVID-19AssociationTesting the structural disconnection hypothesis: Myelin content correlates with memory in healthy aging
Mendez Colmenares A, Thomas M, Anderson C, Arciniegas D, Calhoun V, Choi I, Kramer A, Li K, Lee J, Lee P, Burzynska A. Testing the structural disconnection hypothesis: Myelin content correlates with memory in healthy aging. Neurobiology Of Aging 2024, 141: 21-33. PMID: 38810596, PMCID: PMC11290458, DOI: 10.1016/j.neurobiolaging.2024.05.013.Peer-Reviewed Original ResearchDisconnection hypothesisVirginia Cognitive Aging ProjectHypothesis of cognitive agingFractional anisotropyAssociated with reduced memory performanceDeterioration of white matterAge-related memory lossPrefrontal white matterGenu of the corpus callosumMyelin water fractionVoxel-wise analysisWhite matterCorpus callosumExecutive functionCognitive agingDiffusion tensor imagingMemory performancePrefrontal WMStructural equation modelingWM microstructureAge differencesProcessing speedStructural disconnectionCognitive declineHealthy participantsSearching Reproducible Brain Features using NeuroMark: Templates for Different Age Populations and Imaging Modalities
Fu Z, Batta I, Wu L, Abrol A, Agcaoglu O, Salman M, Du Y, Iraji A, Shultz S, Sui J, Calhoun V. Searching Reproducible Brain Features using NeuroMark: Templates for Different Age Populations and Imaging Modalities. NeuroImage 2024, 292: 120617. PMID: 38636639, PMCID: PMC11416721, DOI: 10.1016/j.neuroimage.2024.120617.Peer-Reviewed Original ResearchConceptsFunctional MRIStructural MRIResting-state scanSpatial similarity analysisMental health researchBrain markersDiffusion MRIAge differencesBrain featuresNeuromarkersBrain disordersYoung adult cohortBrain developmentWell-replicatedHuman brainBrainDiffusion MRI dataData-driven analysisDisordersSimilarity analysisAge cohortsGeneralizabilityPopulation-based researchAdult cohortAge-specific adaptation
2023
Correlations between APOE4 status and regional amyloid and tau burdens in cognitively normal older individuals
Hong Y, Kim C, Lee J, Sepulcre J. Correlations between APOE4 status and regional amyloid and tau burdens in cognitively normal older individuals. Alzheimer's & Dementia 2023, 19 DOI: 10.1002/alz.065023.Peer-Reviewed Original ResearchApolipoprotein epsilon 4Standardized uptake value ratioCarrier statusCortical thicknessPositron emission tomographyApolipoprotein epsilon 4 statusTau burdenCognitively normal older individualsAPOE4 carriersRegional amyloidNon-carriersCross-sectional studyNormal older individualsCognitively normal participantsFlorbetapir positron emission tomographyNormal cognitive functionAPOE4 non-carriersAssociated with amyloid depositionRegional tau burdenCognitive functionAD-related biomarkersAge differencesPhosphorylated tauNormal participantsClinical characteristicsMultimodal study of the neural sources of error monitoring in adolescents and adults
Conte S, Richards J, Fox N, Valadez E, McSweeney M, Tan E, Pine D, Winkler A, Liuzzi L, Cardinale E, White L, Buzzell G. Multimodal study of the neural sources of error monitoring in adolescents and adults. Psychophysiology 2023, 60: e14336. PMID: 37212619, PMCID: PMC10524909, DOI: 10.1111/psyp.14336.Peer-Reviewed Original ResearchConceptsDorsal anterior cingulate cortexEvent-related potentialsError monitoringGoal-directed behaviorUnderlying neural mechanismsAnterior cingulate cortexAge-related differencesPerformance monitoringTemperamental riskERN componentIndividual differencesN2 componentNeural mechanismsNeural responsesAge differencesNeural generatorsCingulate cortexNeural sourcesFunctional MRIAdult participantsMultimodal studyPatterns of activityDevelopmental changesROI analysisAdult groupSymmetric data-driven fusion of diffusion tensor MRI: Age differences in white matter
Colmenares A, Hefner M, Calhoun V, Salerno E, Fanning J, Gothe N, McAuley E, Kramer A, Burzynska A. Symmetric data-driven fusion of diffusion tensor MRI: Age differences in white matter. Frontiers In Neurology 2023, 14: 1094313. PMID: 37139071, PMCID: PMC10149813, DOI: 10.3389/fneur.2023.1094313.Peer-Reviewed Original ResearchDiffusion tensor imagingAge differencesExamination of age differencesPattern of age differencesFractional anisotropyRadial diffusivityJoint independent component analysisCognitively healthy adultsWhite matterDiffusion tensor imaging parametersFluid abilitiesPrefrontal WMProcessing speedDiagnostic classificationWM pathologyDiffusion tensor imaging datasetsAging WMUnimodal analysisTensor imagingIndependent component analysisClinical samplesHealthy agingCognitionCorpus callosumHealthy adultsAging a Decade in a Day: Age Cutoff Bias in Adjuvant Therapy Allocation for Early-Stage Breast Cancer
Talcott W, Cain D, Yang D, Mougalian S, Evans S. Aging a Decade in a Day: Age Cutoff Bias in Adjuvant Therapy Allocation for Early-Stage Breast Cancer. International Journal Of Radiation Oncology • Biology • Physics 2023, 116: 747-756. PMID: 37125983, DOI: 10.1016/j.ijrobp.2022.12.057.Peer-Reviewed Original ResearchConceptsEarly-stage breast cancerAdjuvant therapy recommendationsMultivariable logistic regressionTherapy recommendationsBreast cancerAge 70Cohort 2Odds ratioCohort 1Years age differenceLogistic regressionNational Cancer DatabaseHigh-risk featuresHormone receptor positivityConfidence intervalsAdjuvant treatmentEndocrine therapyPatient ageIndependent predictorsReceptor positivityTherapy allocationAge 69Cancer DatabaseTreatment allocationAge differences
2021
Effectiveness of a Web-Based Tobacco Product use Prevention Videogame Intervention on Young Adolescents’ Beliefs and Knowledge
Hieftje KD, Fernandes CF, Lin IH, Fiellin LE. Effectiveness of a Web-Based Tobacco Product use Prevention Videogame Intervention on Young Adolescents’ Beliefs and Knowledge. Substance Abuse 2021, 42: 47-53. PMID: 31825759, DOI: 10.1080/08897077.2019.1691128.Peer-Reviewed Original ResearchConceptsTobacco product useVideogame interventionE-cigarettesElectronic cigarettesProduct useMcNemar testKnowledge questionsSingle group pre-post studyTobacco product initiationPre-post studySignificant differencesCigarette smokingProduct initiationTobacco useUse preventionHealthy beliefsPromising effectsKnowledge surveyInterventionVapingCigarettesDescriptive statisticsAdolescentsCorrect answersAge differences
2019
Identification of new biomarkers of bronchopulmonary dysplasia using metabolomics
Piersigilli F, Lam TT, Vernocchi P, Quagliariello A, Putignani L, Aghai ZH, Bhandari V. Identification of new biomarkers of bronchopulmonary dysplasia using metabolomics. Metabolomics 2019, 15: 20. PMID: 30830433, DOI: 10.1007/s11306-019-1482-9.Peer-Reviewed Original ResearchConceptsBronchopulmonary dysplasiaPreterm neonatesNew biomarkersNeonatal intensive care unitMost preterm infantsIntensive care unitNovel specific biomarkersTracheal aspirate samplesSub-group analysisGestational age differencesPreterm infantsCare unitAspirate samplesNeonatesSpecific biomarkersFirst weekC16-OHIsoleucine levelsSelect metabolitesBiomarkersDysplasiaPartial least squares discriminant analysisLeast squares discriminant analysisSquares discriminant analysisAge differences
2017
Gender and Age Differences in Sleep Problems in Children: Person-Oriented Approach With Multigroup Analysis
Chen YL, Tseng WL, Yang LK, Gau SS. Gender and Age Differences in Sleep Problems in Children: Person-Oriented Approach With Multigroup Analysis. Behavioral Sleep Medicine 2017, 17: 302-313. PMID: 28753086, DOI: 10.1080/15402002.2017.1357117.Peer-Reviewed Original ResearchConceptsPerson-oriented approachSleep problemsAge groupsPrevalence ratesMultigroup analysisSleep-related breathing problemsVaried prevalence ratesAge-specific interventionsSleep Habits QuestionnaireHigh sleep problemsDifferent prevalence ratesAssociated FactorsParent reportAge differencesBreathing problemsHabits QuestionnaireEpidemiological sampleLatent class modelingSubtypesChildrenFuture studiesGenderGroupClass modelingParasomniasPREDICTORS OF CRASHES AND MOVING VIOLATIONS IN A DIVERSE SAMPLE OF OLDER WOMEN: THE WHIMS STUDIES
Marottoli R, Dugan E, Gaussoin S, Naughton M, Rapp S, Snively B, Vaughan L. PREDICTORS OF CRASHES AND MOVING VIOLATIONS IN A DIVERSE SAMPLE OF OLDER WOMEN: THE WHIMS STUDIES. Innovation In Aging 2017, 1: 650-650. PMCID: PMC6247174, DOI: 10.1093/geroni/igx004.2305.Peer-Reviewed Original ResearchSelf-reported crashesPredictors of crashesAdverse driving outcomesCognitive health outcomesLower cognitive scoresWHI Memory StudyAdverse driving eventsWHI hormone therapy trialsDriving outcomesOlder DriversAge differencesCognitive scoresHormone therapy trialsMemory studiesOlder US womenSocial supportDiverse sampleDriving eventsParticipantsTelephone questionnaireOlder womenUS womenAge 50Therapy trialsHealth outcomes
2016
A survey of skin-to-skin contact with perinatal nurses
Vittner D, Cong X, Ludington-Hoe S, McGrath J. A survey of skin-to-skin contact with perinatal nurses. Applied Nursing Research 2016, 33: 19-23. PMID: 28096017, DOI: 10.1016/j.apnr.2016.09.006.Peer-Reviewed Original ResearchConceptsImplementation of SSCNurses' responsesPerinatal nursesEducation levelPractice settingsYears of nursing practicePrimary practice settingKnowledge-practice gapCross-sectional survey designSkin-to-skin contactYears of practiceNurses' knowledgeNursing practiceOrdered logistic regressionSSC implementationNursesNurse objectsDescriptive statisticsLogistic regressionSurvey designYears experienceInfluence attitudesEducationPracticeAge differencesA Thermal Emotion Classifier for Improved Human-Robot Interaction
Boccanfuso L, Wang Q, Leite I, Li B, Torres C, Chen L, Salomons N, Foster C, Barney E, Ahn Y, Scassellati B, Shic F. A Thermal Emotion Classifier for Improved Human-Robot Interaction. 2016, 718-723. DOI: 10.1109/roman.2016.7745198.Peer-Reviewed Original ResearchHuman-robot interactionAffective responsesImproved human-robot interactionFeatures of speechDimensionality of dataEmotion statesSubtle cuesEmotional statesFacial expressionsEmotion classifierAffective changesAge differencesElectrodermal responsesSocial partnersPerformance accuracySocial engagementRobotBody postureClassifierMore productive collaborationVideo techniquesProductive collaborationEmotionsFaceTemperament
2013
Age-related differences in agenda-driven monitoring of format and task information
Mitchell KJ, Ankudowich E, Durbin KA, Greene EJ, Johnson MK. Age-related differences in agenda-driven monitoring of format and task information. Neuropsychologia 2013, 51: 2427-2441. PMID: 23357375, PMCID: PMC3664244, DOI: 10.1016/j.neuropsychologia.2013.01.012.Peer-Reviewed Original ResearchConceptsOld-new recognitionMedial prefrontal cortexOlder adultsAge-related source memory deficitsPrefrontal cortexRepresentational areaSource memory deficitsVisual processing areasAge-related deficitsPattern of resultsLateral parietal cortexYoung adultsAge-related differencesFeatures of eventsSource memoryEquivalent deficitsReflective attentionParietal functionAge differencesTask informationMemory deficitsGreater trialParietal cortexReduced itemProcessing areas
2011
Long-term Trends in Short-term Outcomes in Acute Myocardial Infarction
Nguyen HL, Saczynski JS, Gore JM, Waring ME, Lessard D, Yarzebski J, Reed G, Spencer FA, Li SX, Goldberg RJ. Long-term Trends in Short-term Outcomes in Acute Myocardial Infarction. The American Journal Of Medicine 2011, 124: 939-946. PMID: 21962314, PMCID: PMC3185241, DOI: 10.1016/j.amjmed.2011.05.023.Peer-Reviewed Original ResearchConceptsAcute myocardial infarctionShort-term outcomesOlder patientsAtrial fibrillationMyocardial infarctionAdverse short-term outcomesGreater Worcester medical centersShort-term death ratesShort-term mortality rateMen 75 yearsShort-term mortalityTargeted treatment approachCardiogenic shockHeart failureMajor complicationsAge differencesElderly menMedical CenterStudy populationMortality rateTreatment approachesPatientsDeath rateFemale residentsWomen
2010
Aversive Effects of Ethanol in Adolescent Versus Adult Rats: Potential Causes and Implication for Future Drinking
Schramm‐Sapyta N, DiFeliceantonio AG, Foscue E, Glowacz S, Haseeb N, Wang N, Zhou C, Kuhn CM. Aversive Effects of Ethanol in Adolescent Versus Adult Rats: Potential Causes and Implication for Future Drinking. Alcohol Clinical And Experimental Research 2010, 34: 2061-2069. PMID: 20860614, PMCID: PMC2988872, DOI: 10.1111/j.1530-0277.2010.01302.x.Peer-Reviewed Original ResearchConceptsAversive effectsAdolescents Versus AdultsProblem drinking behaviorDrug seeking behaviorBlood ethanol concentrationTaste aversionFuture drinkingAdolescent ratsAge differencesDrugs of abuseEthanol CTADrug takingDrinking behaviorAdolescentsPhysiologic effectsAdult ratsTeenage yearsIndividual variationRodent studiesAbuseAdultsSeeking behaviourDrug intakeEpidemiological evidenceSedative effectsAdolescent Maturation of D1 and D2 Dopamine Receptor Interactions
Dwyer J, Martinez L, Ganddini G, Perez M, Leslie F. Adolescent Maturation of D1 and D2 Dopamine Receptor Interactions. The FASEB Journal 2010, 24: 766.1-766.1. DOI: 10.1096/fasebj.24.1_supplement.766.1.Peer-Reviewed Original ResearchD1/D2 interactionsDopamine receptor interactionsMesocorticolimbic dopamine systemImmediate early gene expressionDopaminergic drugsReceptor changesD2 agonistDirect agonistsIndirect agonistsAdult ratsLimbic systemDopamine systemDirect D1Neuropsychiatric disordersEarly gene expressionFunctional connectivityNeural circuitryDA systemBehavioral responsesAgonistsC-fosAge differencesPhRMA FoundationAdolescent maturationReceptor interaction
2009
Mechanisms underlying age differences in dopaminergic drug sensitivity
Dwyer J, Buntrock L, Khalaj A, Martinez L, Leslie F. Mechanisms underlying age differences in dopaminergic drug sensitivity. The FASEB Journal 2009, 23: 745.3-745.3. DOI: 10.1096/fasebj.23.1_supplement.745.3.Peer-Reviewed Original ResearchNeural stress systemsCritical developmental periodAge differencesNeural circuitryAdolescenceDevelopmental periodBehavioral differencesBehavioral responsesStress systemDrug abuseIndirect dopamineStereotypic behaviorAdolescentsNeuropsychiatric disordersD2-like agonist quinpiroleImportant implicationsAdult male ratsImmediate early gene expressionAgonist quinpiroleReceptor changesAdulthoodMale ratsAbuseEarly gene expressionQuinpirole
2006
Age, rank, and personality effects on the cortisol sedation stress response in young chimpanzees
Anestis S, Bribiescas R, Hasselschwert D. Age, rank, and personality effects on the cortisol sedation stress response in young chimpanzees. Physiology & Behavior 2006, 89: 287-294. PMID: 16887152, DOI: 10.1016/j.physbeh.2006.06.010.Peer-Reviewed Original ResearchConceptsCortisol responseIndividual differencesPersonality effectsBaseline cortisolAge differencesYoung chimpanzeesAdolescent chimpanzeesPsychosocial stressorsStyle scoresRank-related differencesSedation measuresStress measuresCortisol changesStyle componentsHigher baseline levelsOlder individualsGreater stress responseIndividualsCortisol levelsYoung individualsPersonalityChimpanzeesMeasuresStress responseFuture studies
2000
The Mother-Child Dyad Facing Trauma
WOLMER L, LAOR N, GERSHON A, MAYES L, COHEN D. The Mother-Child Dyad Facing Trauma. The Journal Of Nervous And Mental Disease 2000, 188: 409-415. PMID: 10919698, DOI: 10.1097/00005053-200007000-00003.Peer-Reviewed Original Research
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